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21. 发明申请

US20050136034A1 Uses of IL-12 in hematopoiesis 有权
标题翻译：在造血中使用IL-12
公开(公告)号：US20050136034A1
公开(公告)日：2005-06-23
申请号：US10886267
申请日：2004-07-06
申请人： Tingchao Chen , Yi Zhao , W. Anderson
发明人： Tingchao Chen , Yi Zhao , W. Anderson
IPC分类号： A61K38/20 , A61K45/00 , A61N5/00
CPC分类号： A61K38/208 , A61K31/675 , A61K38/193 , A61K45/06 , A61N5/10 , A61N2005/1098 , C07K14/53 , C07K14/5434 , A61K2300/00
摘要： Embodiments of the present invention are directed to uses of Interleukin-12 (IL-12) in enhancing or stimulating hematopoiesis to yield hematopoietic recovery in a mammal in need. Particular embodiments of the invention are directed to uses of IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other embodiments include uses of IL-12 to ameliorate various hematopoietic deficiencies. Still other embodiments are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cell, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed embodiments are directed to uses of Il-12 for bone marrow preservation or recovery.
摘要翻译：本发明的实施方案涉及白细胞介素-12（IL-12）在增强或刺激造血作用以在需要的哺乳动物中产生造血恢复的用途。本发明的具体实施方案涉及IL-12用作辅助治疗以减轻与用于对抗疾病状态的一种或多种治疗方案相关的造血毒性的用途。其它实施方案包括IL-12的用途来改善各种造血缺陷。其它实施方案涉及IL-12用于造血细胞再生细胞，造血祖细胞和造血干细胞的体内增殖的用途。其他公开的实施方案涉及II-12用于骨髓保存或回收的用途。

22. 发明授权

US06233561B1 Method for goal-oriented speech translation in hand-held devices using meaning extraction and dialogue 有权
标题翻译：使用意义提取和对话的手持设备中面向目标的语音翻译方法
公开(公告)号：US06233561B1
公开(公告)日：2001-05-15
申请号：US09290628
申请日：1999-04-12
申请人： Jean-Claude Junqua , Roland Kuhn , Matteo Contolini , Murat Karaorman , Ken Field , Michael Galler , Yi Zhao
发明人： Jean-Claude Junqua , Roland Kuhn , Matteo Contolini , Murat Karaorman , Ken Field , Michael Galler , Yi Zhao
IPC分类号： G10L1522
CPC分类号： G10L15/1822 , G10L15/1815
摘要： A computer-implemented method and apparatus is provided for processing a spoken request from a user. A speech recognizer converts the spoken request into a digital format. A frame data structure associates semantic components of the digitized spoken request with predetermined slots. The slots are indicative of data which are used to achieve a predetermined goal. A speech understanding module which is connected to the speech recognizer and to the frame data structure determines semantic components of the spoken request. The slots are populated based upon the determined semantic components. A dialog manager which is connected to the speech understanding module may determine at least one slot which is unpopulated based upon the determined semantic components and in a preferred embodiment may provide confirmation of the populated slots. A computer generated-request is formulated in order for the user to provide data related to the unpopulated slot. The method and apparatus are well-suited (but not limited) to use in a hand-held speech translation device.
摘要翻译：提供了一种用于处理来自用户的口头请求的计算机实现的方法和装置。语音识别器将口头请求转换为数字格式。帧数据结构将数字化语音请求的语义分量与预定时隙相关联。这些时隙指示用于实现预定目标的数据。连接到语音识别器和帧数据结构的语音理解模块确定语音请求的语义分量。基于确定的语义分量来填充时隙。连接到语音理解模块的对话管理器可以基于所确定的语义组件来确定未填充的至少一个时隙，并且在优选实施例中可以提供填充时隙的确认。制定计算机生成请求以便用户提供与未填充槽相关的数据。该方法和装置非常适合（但不限于）在手持语音翻译装置中使用。

23. 外观设计

USD983164S1 Audio headset 有权
公开(公告)号：USD983164S1
公开(公告)日：2023-04-11
申请号：US29785489
申请日：2021-05-26
申请人： YI ZHAO ( SHENZHEN ) CO., LIMITED
设计人： Mingxun Zheng

24. 外观设计

USD980190S1 Audio headset 有权
公开(公告)号：USD980190S1
公开(公告)日：2023-03-07
申请号：US29785491
申请日：2021-05-26
申请人： YI ZHAO (SHENZHEN) CO., LIMITED
设计人： Mingxun Zheng

25. 外观设计

USD980186S1 Audio headset 有权
公开(公告)号：USD980186S1
公开(公告)日：2023-03-07
申请号：US29785494
申请日：2021-05-26
申请人： YI ZHAO (SHENZHEN) CO., LIMITED
设计人： Mingxun Zheng

26. 发明授权

US09402882B2 Method for bone marrow preservation or recovery 有权
标题翻译：骨髓保存或恢复方法
公开(公告)号：US09402882B2
公开(公告)日：2016-08-02
申请号：US12756995
申请日：2010-04-08
申请人： Tingchao Chen , Yi Zhao , W. French Anderson
发明人： Tingchao Chen , Yi Zhao , W. French Anderson
IPC分类号： A61K38/20 , C07K14/54 , A61P35/02 , A61P7/06 , A61K45/06 , A61N5/10 , A61K31/675
CPC分类号： A61K38/208 , A61K31/675 , A61K38/193 , A61K45/06 , A61N5/10 , A61N2005/1098 , C07K14/53 , C07K14/5434 , A61K2300/00
摘要： Methods for enhancing or stimulating hematopoiesis including the step of administering Interleukin-12 (IL-12) to yield hematopoietic recovery in a mammal in need. Preferred methods include the step of administering IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other methods include administering IL-12 to ameliorate various hematopoietic deficiencies. Still other methods are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed methods are directed to uses of IL-12 for bone marrow preservation or recovery.
摘要翻译：用于增强或刺激造血的方法，包括施用白细胞介素-12（IL-12）以在需要的哺乳动物中产生造血回收的步骤。优选的方法包括施用IL-12作为辅助治疗以减轻与用于对抗疾病状态的一种或多种治疗方案相关的造血毒性的步骤。其他方法包括给予IL-12以改善各种造血缺陷。还有其它方法涉及IL-12用于造血再生细胞，造血祖细胞和造血干细胞的体内增殖的用途。其他公开的方法涉及IL-12用于骨髓保存或恢复的用途。

27. 发明授权

US09371330B2 Substituted pyrazino[1,2-a]pyrimidines useful as CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells 有权
标题翻译：可用作CBP /连环蛋白拮抗剂的取代的吡嗪并[1,2-a]嘧啶，用于增强体细胞干细胞的不对称分裂
公开(公告)号：US09371330B2
公开(公告)日：2016-06-21
申请号：US14350342
申请日：2012-05-15
申请人： Michael Kahn , Jia-Ling Teo , Michael McMillan , Yi Zhao , Yongfeng Wu
发明人： Michael Kahn , Jia-Ling Teo , Michael McMillan , Yi Zhao , Yongfeng Wu
IPC分类号： A61K31/4985 , C07D241/38 , C07D487/04
CPC分类号： C07D487/04
摘要： Provided are: composition and methods for: treating aging or an age-related condition, symptom or disease; stimulating hair growth, regrowth or pigmentation (or preventing hair loss); for increasing adenosine receptor expression in dermal cells (in combination with hair growth); for treating a condition or disease of the skin or at least one symptom thereof, including cosmetic treatment (e.g., wrinkles, hyperpigmentation, redness, rosacea, dryness, cracking, loss of firmness, loss of elasticity, thinning, and loss of vibrancy). The methods comprise administering a sufficient amount of the disclosed CBP/catenin (e.g., CBP/(β-catenin) antagonist compositions, and particularly wherein administration is in an amount and manner sufficient to provide for increasing the number of asymmetric renewing divisions relative to, or at the expense of symmetric divisions in relevant somatic stem cell population. In particular aspects, the CBP/catenin (e.g., CBP/(β-catenin) antagonist comprises an alkyl and/or fatty acid ester derivative of formula (I) as disclosed herein
摘要翻译：提供：用于治疗老化或年龄相关病症，症状或疾病的组合物和方法; 刺激头发生长，再生长或色素沉着（或防止脱发）; 用于增加真皮细胞中的腺苷受体表达（与头发生长结合）; 用于治疗皮肤或其至少一种症状的病症或疾病，包括美容治疗（例如皱纹，色素沉着过度，发红，红斑痤疮，干燥，开裂，硬度丧失，弹性丧失，变薄和活力丧失）。所述方法包括施用足量的所公开的CBP /连环蛋白（例如CBP /（＆bgr-连翘蛋白）拮抗剂组合物），特别是其中给药的量和方式足以提供增加不对称更新分隔数相对于在特定方面，CBP /连环蛋白（例如，CBP /（＆bgr-连环蛋白）拮抗剂）包含式（I）的烷基和/或脂肪酸酯衍生物，或者以相关体细胞干细胞群体的对称分裂为代价。如本文所公开的

28. 发明授权

US08897156B2 Method and apparatus for uplink synchronization control 有权
标题翻译：用于上行链路同步控制的方法和装置
公开(公告)号：US08897156B2
公开(公告)日：2014-11-25
申请号：US13320537
申请日：2010-05-11
申请人： Zhixue Wang , Guoqing Li , Yi Zhao , Jiamin Liu , Yali Zhao , Fangli Xu
发明人： Zhixue Wang , Guoqing Li , Yi Zhao , Jiamin Liu , Yali Zhao , Fangli Xu
IPC分类号： H04J3/14 , H04J3/06
CPC分类号： H04W56/0045 , H04W92/10
摘要： The present invention discloses a method for uplink synchronization control, wherein network side and a user equipment (UE) maintain a timing alignment timer (TAT) for the UE, and maintain an uplink transmission timing adjustment amount for uplink component carriers, and the method includes following steps: the network side measuring uplink component carriers of the UE, and obtaining an uplink transmission TA amount of the uplink component carriers; and before the TAT expires, the network side transmitting to the UE an adjustment command comprising information of the uplink transmission TA amount for at least one of the uplink component carriers of the UE. Also disclosed in the embodiments of the present invention are a method for uplink synchronization control at the UE side, and a base station and a UE for implementing the above methods. The solution of the present invention enables accurate adjustment of the uplink synchronization for each component carrier in a carrier aggregation mechanism.
摘要翻译：本发明公开了一种上行链路同步控制方法，其中网络侧和用户设备（UE）维护用于UE的定时对准定时器（TAT），并维持上行链路分量载波的上行链路传输定时调整量，该方法包括以下步骤：网络侧测量UE的上行链路分量载波，并获得上行链路分量载波的上行链路传输TA量; 并且在TAT到期之前，网络侧向UE发送包括UE的上行链路分量载波中的至少一个的上行链路传输TA的信息的调整命令。在本发明的实施例中也公开了一种用于UE侧的上行链路同步控制的方法，以及用于实现上述方法的基站和UE。本发明的解决方案能够准确地调整载波聚合机制中的每个分量载波的上行链路同步。

29. 发明授权

US08588195B2 Data transmission method, system and apparatus thereof 有权
标题翻译：数据传输方法，系统及其装置
公开(公告)号：US08588195B2
公开(公告)日：2013-11-19
申请号：US13375381
申请日：2010-06-09
申请人： Yi Zhao , Yu Ding , Xiaodong Yang
发明人： Yi Zhao , Yu Ding , Xiaodong Yang
IPC分类号： H04L12/26
CPC分类号： H04L1/0003 , H04L1/0025 , H04W4/06 , H04W28/18
摘要： Disclosed are a data transmission method, a system and an apparatus, which are used to meet transmission quality requirements of data on multiple kinds of logic channels in the event that multiple kinds of logic channels related to multimedia broadcast multicast service (MBMS) are mapped to the same transmission channel. The data transmission method provided by the present invention includes that: a network side determines multiple kinds of modulation and coding schemes (MCSs) needed to be adopted when multiple kinds of logic channels are mapped to the same transmission channel, and notifies a terminal of correspondence between logic channels and MCSs; using MCSs needed to be adopted, the network side performs modulation and coding for the data on logic channels mapped to the transmission channel, then transmits it to the terminal through the transmission channel.
摘要翻译：公开了一种数据传输方法，系统和装置，其用于在多媒体广播多播服务（MBMS）相关的多种逻辑信道被映射到多个逻辑信道的情况下满足多种逻辑信道上的数据的传输质量要求相同的传输通道。本发明提供的数据传输方法包括：当多个逻辑信道被映射到相同的传输信道时，网络侧确定需要采用的多种调制和编码方案（MCS），并将终端通信逻辑通道和MCS之间; 使用需要采用的MCS，网络侧对映射到传输信道的逻辑信道上的数据执行调制和编码，然后通过传输信道将其发送到终端。

30. 发明申请

US20120196559A1 Notification Method, System and Apparatus for an Emergency Area ID 有权
标题翻译：紧急区域ID的通知方法，系统和设备
公开(公告)号：US20120196559A1
公开(公告)日：2012-08-02
申请号：US13258256
申请日：2010-04-27
申请人： Yi Zhao , Tao Lu
发明人： Yi Zhao , Tao Lu
IPC分类号： H04W4/22
CPC分类号： H04W24/02 , H04W24/04 , H04W76/50 , H04W88/08
摘要： The disclosure provides a notification method for an Emergency Area ID, including: an evolution node B (eNB) acquires an eNB-supported Emergency Area ID and an E-UTRAN cell global identifier (E-CGI) list included in it, and when S1 is set up, carries the acquired emergency area ID and the E-CGI list included in it in an S1 setup request message to transmit to a mobility management entity (MME); the MME stores the received emergency area ID and the E-CGI list included in it. The disclosure further provides a notification system for an Emergency Area ID. With the disclosure, the complexity of manual operation and the error rate are decreased, the reliability and operating efficiency of the system are improved, and the stability and maintainability of the system are enhanced.
摘要翻译：本公开提供了一种紧急区域ID的通知方法，包括：演进节点B（eNB）获取包含在其中的eNB支持的紧急区域ID和E-UTRAN小区全局标识符（E-CGI）列表，并且当S1 在S1建立请求消息中携带获取的紧急区域ID和包含在其中的E-CGI列表，以发送到移动性管理实体（MME）; MME存储接收的紧急区域ID和包含在其中的E-CGI列表。本发明还提供了一种用于紧急区域ID的通知系统。据了解，手动操作的复杂性和错误率降低，提高了系统的可靠性和运行效率，提高了系统的稳定性和可维护性。

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