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21. 发明授权

US07082336B2 Implantable intravascular device for defibrillation and/or pacing 有权
标题翻译：用于除颤和/或起搏的植入式血管内装置
公开(公告)号：US07082336B2
公开(公告)日：2006-07-25
申请号：US10454223
申请日：2003-06-04
申请人： Terrance Ransbury , Michael S. Williams
发明人： Terrance Ransbury , Michael S. Williams
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/056 , A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one lead attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The lead or leads are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.
摘要翻译：本申请描述了血管内可植入起搏和/或除颤系统。所描述的系统包括脉冲发生器，该脉冲发生器可植入在血管内并且与通过血管的血液流动成比例，以及可附接到脉冲发生器的至少一个引线。在植入期间，将脉冲发生器引入患者的脉管系统中，前进到期望的血管并锚定在血管内的适当位置。根据需要将引线或引线放置在心脏或周围血管内，以将电脉冲传递到适当的位置。

22. 发明授权

US09067071B2 System and method for neuromodulation 有权
标题翻译：神经调节系统和方法
公开(公告)号：US09067071B2
公开(公告)日：2015-06-30
申请号：US13547031
申请日：2012-07-11
申请人： William E. Sanders , Stephen C. Masson , Terrance Ransbury , Richard S. Stack
发明人： William E. Sanders , Stephen C. Masson , Terrance Ransbury , Richard S. Stack
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36114 , A61N1/0551 , A61N1/056 , A61N1/36053 , A61N1/36135 , A61N1/36139
摘要： A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed in a superior vena cava of the patient to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element disposed within the superior vena cava to deliver therapy to a sympathetic cardiac nerve fiber. A neuromodulation system includes a parasympathetic therapy element adapted for positioning within a blood vessel, a sympathetic therapy element adapted for positioning within the blood vessel; and a stimulator to energize the parasympathetic therapy element to deliver parasympathetic therapy to a parasympathetic nerve fiber disposed external to the blood vessel and energize the sympathetic therapy element within the blood vessel to deliver sympathetic therapy to a sympathetic nerve fiber disposed external to the blood vessel. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.
摘要翻译：一种治疗患者自主性不平衡的方法包括激励设置在患者上腔静脉中的第一治疗元件，以将治疗递送至副交感神经纤维（例如迷走神经），以及激励位于上腔静脉内的第二治疗元件为交感神经纤维提供治疗。神经调节系统包括适于定位在血管内的副交感神经治疗元件，适于定位在血管内的交感治疗元件; 以及刺激器，用于激励所述副交感神经治疗元件以将副交感神经治疗递送到设置在所述血管外部的副交感神经纤维，并激励所述血管内的所述交感神经治疗元件，以将交感神经治疗递送至设置在所述血管外部的交感神经纤维。该疗法可降低患者的心率，提高或维持患者的血压。

23. 发明申请

US20130222139A1 HUMAN SAFETY INDICATOR 有权
标题翻译：人类安全指标
公开(公告)号：US20130222139A1
公开(公告)日：2013-08-29
申请号：US13594300
申请日：2012-08-24
申请人： Charles Mack Gouge , Kenneth Armstrong , Terrance Ransbury , Robert Smith , Darrel Self
发明人： Charles Mack Gouge , Kenneth Armstrong , Terrance Ransbury , Robert Smith , Darrel Self
IPC分类号： G08B21/02
CPC分类号： G08B21/02 , A61B5/01 , A61B5/02055 , A61B5/1118 , A61B5/6801 , A61B5/6803 , A61B5/681 , A61B5/7405 , A61B5/7455 , A61B5/746 , A61B5/7475 , A61B2560/0431 , G01K13/002
摘要： A human safety system includes a circuit including a microcontroller and at least one power source; a probe in communication with the circuit; at least one use detector in communication with the circuit; and at least one alert indicator in communication with the circuit. A method of using a human safety device, the method includes initiating operation of the human safety device; arranging the human safety device in communication with skin; and monitoring the human safety device for alert indicators. A method of monitoring a user includes waking from sleep state; sensing at least one condition of the user; determining if the sensed condition is in a human condition; continuously monitoring the condition of the user; and, returning to sleep state when the user condition is outside of the human condition for an amount of time.
摘要翻译：人体安全系统包括包括微控制器和至少一个电源的电路; 与电路通信的探头; 至少一个使用检测器与电路通信; 以及与电路通信的至少一个警报指示器。一种使用人体安全装置的方法，所述方法包括启动人体安全装置的操作; 安排人体安全装置与皮肤通信; 并监控人体安全装置的警报指示。监视用户的方法包括从睡眠状态唤醒; 感测用户的至少一个条件; 确定感测到的状况是否处于人的状况; 持续监控用户的状况; 并且当用户状态超出人类状况一段时间时返回睡眠状态。

24. 发明申请

US20110004288A1 INTRAVASCULAR IMPLANTABLE DEVICE HAVING INTEGRATED ANCHOR MECHANISM 审中-公开
标题翻译：具有集成锚固机构的血管内植入装置
公开(公告)号：US20110004288A1
公开(公告)日：2011-01-06
申请号：US12815355
申请日：2010-06-14
申请人： Terrance Ransbury
发明人： Terrance Ransbury
IPC分类号： A61F2/82 , A61F2/84
CPC分类号： A61N1/375
摘要： Devices, systems and methods are provided for an intravascular implantable device having an integrated anchor mechanism that can be deployed by compressing the anchor in an axial direction. Various embodiments address the various issues presented by the prior art and/or improve upon the prior art devices, methods and systems for anchoring an intravascular implantable device within a vessel.
摘要翻译：为具有集成锚定机构的血管内可植入装置提供了装置，系统和方法，所述锚定机构可以通过沿轴向压缩锚固部而展开。各种实施例解决现有技术提出的各种问题和/或改进用于将血管内可植入装置锚定在血管内的现有技术装置，方法和系统。

25. 发明申请

US20100318166A1 METHODS AND SYSTEMS FOR ANTI-THROMBOTIC INTRAVASCULAR IMPLANTABLE DEVICES 审中-公开
标题翻译：抗血栓性血管内植入物的方法与系统
公开(公告)号：US20100318166A1
公开(公告)日：2010-12-16
申请号：US12815210
申请日：2010-06-14
申请人： Terrance Ransbury
发明人： Terrance Ransbury
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/37205 , A61N1/3756
摘要： An implantable intravascular medical device, and methods related to the implantable intravascular device, includes a plurality of containers connected by flex couplers which are configured for implantation in such a manner as to improve vascular response and reduce thrombosis resulting from chronic implantation of the device.
摘要翻译：可植入血管内医疗装置和与可植入血管内装置相关的方法包括通过挠性联接器连接的多个容器，其被配置为以改善血管反应并减少由于装置的慢性植入引起的血栓形成的方式植入。

26. 发明授权

US07617007B2 Method and apparatus for retaining medical implants within body vessels 有权
标题翻译：保留体内血管植入物的方法和装置
公开(公告)号：US07617007B2
公开(公告)日：2009-11-10
申请号：US10977060
申请日：2004-10-29
申请人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Kevin Holbrook
发明人： Michael S. Williams , Terrance Ransbury , Richard A. Glenn , Kevin Holbrook
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译：本申请描述了用于将医疗装置锚定在脉管系统内的保持装置。该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物递送系统。

27. 发明申请

US20090198251A1 LEAD DELIVERY, FIXATION AND EXTRACTION DEVICES AND METHODS FOR USE WITH INTRAVASCULAR IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：引导输送，固定和提取装置及其与内膜可植入装置的使用方法
公开(公告)号：US20090198251A1
公开(公告)日：2009-08-06
申请号：US12367475
申请日：2009-02-06
申请人： Terrance Ransbury , Ryan McCormick
发明人： Terrance Ransbury , Ryan McCormick
IPC分类号： A61B19/00
CPC分类号： A61N1/0573 , A61M25/0068 , A61N1/056 , A61N2001/0578
摘要： A lead delivery and fixation device for use with an intravascular implantable device includes a sidecar having a selectively retractable fixation element. A lead is releasably coupled to the sidecar, with an electrode portion exposed for delivering a stimulation therapy. A manipulable catheter is coupled to the fixation element and configured to advance and withdraw a helix portion of the fixation element. The catheter and fixation element are offset from and generally parallel to the lead. The lead is separable from the sidecar in the event that extraction is required.
摘要翻译：用于与血管内可植入装置一起使用的引导输送和固定装置包括具有可选择性缩回的固定元件的侧片。引线可释放地耦合到旁边，其中暴露电极部分用于递送刺激疗法。可操纵导管联接到固定元件并且构造成前进和退出固定元件的螺旋部分。导管和固定元件偏离并大致平行于引线。在需要提取的情况下，铅可以与侧面分离。

28. 发明申请

US20090182347A1 IMPLANTATION METHODS, SYSTEMS AND TOOLS FOR CARDIAC LEADS ASSOCIATED WITH INTRAVASCULAR IMPLANTABLE DEVICES 审中-公开
标题翻译：与静脉注射装置相关的心脏病领域的植入方法，系统和工具
公开(公告)号：US20090182347A1
公开(公告)日：2009-07-16
申请号：US12327791
申请日：2008-12-03
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61B17/00
CPC分类号： A61N1/056 , A61B17/064 , A61B17/068 , A61B2017/0649 , A61M39/0613 , A61N1/0573 , A61N2001/0578
摘要： Improved methods, systems and tools for implanting cardiac leads associated with intravascular implantable devices (IID) within a patient's heart are disclosed. A method is described for implanting a cardiac lead within a patient's heart wherein the proximal end of the cardiac lead is not accessible for introduction of a steerable stylet. A delivery device is described for guiding a cardiac lead to a desired implant location, the delivery device including a grasper mechanism for releasably holding the cardiac lead. The grasper mechanism is on the distal end of an elongated flexible body, and is operated with a handle located on the proximal end of the flexible body.
摘要翻译：公开了用于植入与患者心脏内的血管内可植入装置（IID）相关的心脏引线的改进的方法，系统和工具。描述了一种用于将心脏铅注入患者心脏内的方法，其中心脏导联的近端不可用于引入可导向的心脏管。描述了用于将心脏导联引导到期望的植入位置的递送装置，所述递送装置包括用于可释放地保持心脏引线的抓紧机构。抓紧机构位于细长柔性体的远端，并且用位于柔性体的近端的把手操作。

29. 发明申请

US20080077219A1 Intravascular electrophysiological system and methods 有权
标题翻译：血管内电生理系统和方法
公开(公告)号：US20080077219A1
公开(公告)日：2008-03-27
申请号：US11980006
申请日：2007-10-30
申请人： Michael Williams , Terrance Ransbury , Richard Glenn , Daniel Fifer , Kevin Holbrook
发明人： Michael Williams , Terrance Ransbury , Richard Glenn , Daniel Fifer , Kevin Holbrook
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one electrode attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The electrode or electrodes are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.
摘要翻译：本申请描述了血管内可植入起搏和/或除颤系统。所描述的系统包括脉冲发生器，该脉冲发生器可植入在血管内并与通过血管的血液流动成比例，以及至少一个可附着到脉冲发生器的电极。在植入期间，将脉冲发生器引入患者的脉管系统中，前进到期望的血管并锚定在血管内的适当位置。根据需要将电极或电极放置在心脏或周围血管内，以将电脉冲传递到适当的位置。

30. 发明申请

US20050228471A1 Method and apparatus for retaining medical implants within body vessels 有权
标题翻译：保留体内血管植入物的方法和装置
公开(公告)号：US20050228471A1
公开(公告)日：2005-10-13
申请号：US10977060
申请日：2004-10-29
申请人： Michael Williams , Terrance Ransbury , Richard Glenn , Kevin Holbrook
发明人： Michael Williams , Terrance Ransbury , Richard Glenn , Kevin Holbrook
IPC分类号： A61M31/00 , A61N1/05 , A61N1/372 , A61N1/375
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译：本申请描述了用于将医疗装置锚定在脉管系统内的保持装置。该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物递送系统。

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