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21. 发明授权

US10709637B2 Venous bag clamping mechanism 有权
公开(公告)号：US10709637B2
公开(公告)日：2020-07-14
申请号：US15529933
申请日：2014-11-26
申请人： Sorin Group Italia S.r.l.
发明人： Stefano Spro , Stefano Reggiani , Claudio Silvestri , Francesco Benatti , Adriano Mazzoli
IPC分类号： A61J1/10 , A61J1/14 , A61M1/36 , A61M39/10 , A61M39/28 , A61M5/14
摘要： A venous reservoir including a single inlet line clamp capable of partially or completely restricting blood flow to the venous reservoir. The venous reservoir is provided with a rigid back plate or bracket that can accommodate an inlet line capable of joining to at least one blood inlet port. The rigid back plate or bracket can accommodate a clamp capable of completely or partially closing the inlet line containing both the cardiotomy line and the venous line to manually control the blood flow drained from the patient.

22. 发明申请

US20190143074A1 BI-DIRECTIONAL PERFUSION CANNULA 审中-公开
公开(公告)号：US20190143074A1
公开(公告)日：2019-05-16
申请号：US16242779
申请日：2019-01-08
申请人： Sorin Group Italia S.r.l.
发明人： Randall Moshinsky , James McMillan , Elli Tutungi
IPC分类号： A61M25/00 , A61M1/36
摘要： A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.

23. 发明申请

US20190104986A1 MONITORING SYSTEMS FOR CARDIAC SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS 审中-公开
公开(公告)号：US20190104986A1
公开(公告)日：2019-04-11
申请号：US16211444
申请日：2018-12-06
申请人： Sorin Group Italia S.r.l.
发明人： Marco Ranucci
IPC分类号： A61B5/00 , A61B5/0205 , A61M1/36 , A61B5/145 , A61M1/32 , A61B5/01 , A61M1/14 , G16H40/63 , A61B5/08
摘要： A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.

24. 发明授权

US09867695B2 Minimally-invasive cardiac-valve prosthesis 有权
公开(公告)号：US09867695B2
公开(公告)日：2018-01-16
申请号：US13963191
申请日：2013-08-09
申请人： Sorin Group Italia S.r.l.
发明人： Carla Stacchino , Giovanni Bergamasco , Gaetano Burriesci
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.

25. 发明授权

US09402943B2 Blood processing unit with modified flow path 有权
标题翻译：血液处理单元具有改进的流路
公开(公告)号：US09402943B2
公开(公告)日：2016-08-02
申请号：US14156937
申请日：2014-01-16
申请人： Sorin Group Italia S.r.l. , Politecnico di Milano
发明人： Stefano Reggiani , Gianfranco Beniamino Fiore , Alberto Redaelli , Christian Baiotto
IPC分类号： A61M1/16 , A61M1/32 , B01D63/02 , F28D7/10 , F28D7/16 , F28F21/06 , A61M1/36 , F28D21/00
CPC分类号： A61M1/1698 , A61M1/32 , A61M1/3627 , A61M1/3666 , A61M1/3667 , A61M2206/10 , A61M2206/14 , A61M2206/16 , A61M2206/18 , A61M2206/20 , B01D63/02 , B01D2313/08 , B01D2313/19 , B01D2313/32 , B01D2313/38 , F28D7/103 , F28D7/1623 , F28D21/0015 , F28D2021/005 , F28F13/06 , F28F21/06 , F28F21/062 , F28F2260/00 , Y10S128/03 , Y10S261/28
摘要： A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.
摘要翻译：血液处理装置可以包括热交换器和气体交换器。热交换器和气体交换器中的至少一个可以被配置成赋予径向分量以吹动通过热交换器和/或气体交换器。热交换器可以被配置为使血液流动遵循螺旋流动路径。

26. 发明申请

US20160193044A1 HEART VALVE PROSTHESIS 审中-公开
标题翻译：心脏瓣膜预防
公开(公告)号：US20160193044A1
公开(公告)日：2016-07-07
申请号：US14910975
申请日：2014-07-17
申请人： SORIN GROUP ITALIA S.R.L.
发明人： Monica A. ACHILUZZI
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2/2457 , A61F2220/0033 , A61F2230/0069 , A61F2250/006
摘要： A heart valve prosthesis configured to be implanted at cardiac valve annulus located at an interface between a ventricle (LV) and an atrium (LA), the heart valve prosthesis including: a first portion configured for enclosing a plurality of chordae tendineae (CT) in the ventricle (LV) and native valve leaflets (NVL) to which said chordae tendineae are connected, and a second portion including a radially expandable annular member and a prosthetic heart valve anchored to said radially expandable annular member, wherein said first portion is configured to be implanted in the ventricle (LV), and wherein said second portion is configured to be implanted and coupled to the first portion at the cardiac valve annulus.
摘要翻译：一种心脏瓣膜假体，其构造成植入位于心室（LV）和心房（LA）之间的界面处的心脏瓣膜环处，所述心脏瓣膜假体包括：第一部分，其构造成用于将多个腱索（CT）包围在所述腱索连接到的心室（LV）和天然瓣叶（NVL），以及第二部分，其包括锚定到所述可径向扩张的环形构件的可径向扩张的环形构件和假体心脏瓣膜，其中所述第一部分被配置为植入心室（LV）中，并且其中所述第二部分构造成在心脏瓣膜环处植入和联接到第一部分。

27. 发明申请

US20150374495A1 APPARATUS AND METHOD FOR CHORDAL REPLACEMENT 审中-公开
标题翻译：装置和方法进行替代
公开(公告)号：US20150374495A1
公开(公告)日：2015-12-31
申请号：US14846853
申请日：2015-09-07
申请人： Sorin Group Italia S.r.l.
发明人： Xavier Ruyra Baliarda , Monica Achiluzzi , Laura Ghione
IPC分类号： A61F2/24
CPC分类号： A61F2/2457 , A61F2/2412 , A61F2/2445 , A61F2/2448 , A61F2/2466
摘要： Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.
摘要翻译：描述了一种修复装置和修复具有环状，小叶和腱索的二尖瓣的方法。该装置包括细长带，其包括沿着细长带定位并相对于其朝向环的中心向内突出的多个参考元件，多个参考元件适于接收相应的多个被连接的人造绳到参考元件和适于被切割或移除的多个参考元件以便释放被连接的人造绳。

28. 发明授权

US09162022B2 Oxygenator with integrated arterial filter including filter frame 有权
标题翻译：具有集成动脉过滤器的氧气机，包括过滤器框架
公开(公告)号：US09162022B2
公开(公告)日：2015-10-20
申请号：US13750531
申请日：2013-01-25
申请人： Sorin Group Italia S.r.l. , Politecnico di Milano
发明人： Stefano Reggiani , Claudio Silvestri , Alberto Giri , Alberto Redaelli , Gianfranco Beniamino Fiore
IPC分类号： A61M37/00 , A61M1/16 , A61M1/36 , A61M1/32
CPC分类号： A61M1/1698 , A61M1/322 , A61M1/3627
摘要： An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger, an arterial filter, and a filter frame. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some embodiments, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood.
摘要翻译：氧合器在单个结构中结合了热交换器，气体交换器，动脉过滤器和过滤器框架。这种氧合器允许更少的流体连接，并且因此可以简化体外血液回路，包括使用它的心肺机器和血液储存器。在一些实施例中，氧合器可以被配置为包括用于在过滤血液之前和之后净化气泡的多个吹扫端口。

29. 发明授权

US09138314B2 Prosthetic vascular conduit and assembly method 有权
标题翻译：假体血管导管及装配方法
公开(公告)号：US09138314B2
公开(公告)日：2015-09-22
申请号：US14176533
申请日：2014-02-10
申请人： Sorin Group Italia S.r.l.
发明人： Giovanni Rolando , Paolo Gaschino , Monica Achiluzzi , Felice Giuseppe Carlino
IPC分类号： A61F2/24 , A61F2/06 , A61F2/95
CPC分类号： A61F2/243 , A61F2/06 , A61F2/064 , A61F2/2409 , A61F2/2427 , A61F2/2436 , A61F2002/9522 , Y10T29/49412
摘要： A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.
摘要翻译：用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。导管包括用于接收阀的端子套环构件。套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。

30. 发明授权

US09114010B2 Kit for the manipulation of implantable medical devices 有权
标题翻译：可植入医疗器械的操作套件
公开(公告)号：US09114010B2
公开(公告)日：2015-08-25
申请号：US13849461
申请日：2013-03-22
申请人： Sorin Group Italia S.r.l.
发明人： Paolo Gaschino , Andrea Mariotto , Giovanni Rolando , Massimiliano Ares
IPC分类号： A61F2/24 , A61F2/00 , A61F2/95
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2412 , A61F2002/9522
摘要： A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction. The kit further includes a holder member comprising a first disc support member that includes a central hub and a plurality of bridge elements, wherein the hub and the bridge elements extend axially from opposite sides of the disc support member; and a second ring support member that includes receptacles for coupling with the bridge elements, and a plurality of finger formations protruding axially from the ring member and extending lengthwise along at least a portion of the prosthetic aortic heart valve.
摘要翻译：一种用于促进假体心脏瓣膜的压接以用于植入人心脏中的主动脉瓣部位的试剂盒，所述主动脉瓣部位包括多个瓣膜窦，该试剂盒包括具有管状结构的假体主动脉瓣心脏瓣膜和第一中心轴线包括锚定结构，其包括环形流出构件，环形流入构件以及围绕所述中心轴线成角度地分布成对的多个轴向连接结构，以及耦合到所述锚定结构并且适于基本上允许血液流动的多个叶片第一方向并且基本上防止在第二方向上的血液流动。该套件还包括保持器构件，其包括第一盘支撑构件，该第一盘支撑构件包括中心轮毂和多个桥接元件，其中轮毂和桥接元件从盘支撑构件的相对侧轴向延伸; 以及第二环支撑构件，其包括用于与所述桥接元件联接的插座，以及从所述环构件轴向突出并沿所述假体主动脉瓣心脏的至少一部分纵向延伸的多个指状结构。

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