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11. 发明申请

US20120220691A1 PROCESS FOR THE SYNTHESIS OF METHACRYLATE-DERIVATIZED TYPE-1 COLLAGEN AND DERIVATIVES THEREOF 有权
标题翻译：合成甲基丙烯酸衍生型1型胶原及其衍生物的方法
公开(公告)号：US20120220691A1
公开(公告)日：2012-08-30
申请号：US13249134
申请日：2011-09-29
申请人： David Shreiber , Ian Gaudet
发明人： David Shreiber , Ian Gaudet
IPC分类号： C08L89/00 , C08G69/26
CPC分类号： A61L15/32 , A61L15/60 , A61L27/24 , A61L27/52 , A61L27/60 , A61L2430/34 , C08F8/10 , C08F220/06 , C08F220/34 , C08H1/06 , C08J3/075 , C08J2389/00
摘要： Methods for synthesizing a methacrylate-derivatized type-I collagen in which methacrylic acid is reacted with a carboxylic acid activating reagent in the presence of a carbodiimide to form a methacrylic acid with an activated carboxylic acid group, which is then reacted with free amino groups on type-I collagen to form a collagen methacrylamide. Methacrylate-derivatized collagen, cross-linked collagens formed therefrom and products containing the cross-linked collagen are also disclosed.
摘要翻译：合成甲基丙烯酸酯衍生的I型胶原的方法，其中甲基丙烯酸与羧酸活化剂在碳二亚胺存在下反应形成具有活化羧酸基团的甲基丙烯酸，然后与游离氨基反应， I型胶原蛋白形成胶原甲基丙烯酰胺。还公开了甲基丙烯酸酯衍生的胶原蛋白，由其形成的交联胶原和含有交联胶原的产物。

12. 发明授权

US08236425B2 Long-chain polymethylene halide telomers 有权
标题翻译：长链聚亚甲基卤衍生物
公开(公告)号：US08236425B2
公开(公告)日：2012-08-07
申请号：US12519573
申请日：2007-12-27
申请人： George G. I. Moore , Yu Yang , Richard M. Flynn
发明人： George G. I. Moore , Yu Yang , Richard M. Flynn
IPC分类号： B32B27/00
CPC分类号： C08F2/38 , C07C17/275 , C07C19/14 , C07C19/16 , C07C43/126 , C07C69/63 , C07C309/82 , C07C311/09 , C08F8/10 , C08F8/12 , C08F8/14 , C08F120/24 , C08F120/36 , C08F220/24 , C08G18/2885 , C09D175/04 , D06M15/256 , Y10T428/3154 , C08F110/02
摘要： A composition comprises a distribution of telomers of ethylene and at least one fluoroalkyl or perfluoroalkyl halide, the telomers comprising at least one polymethylene segment (—(CH2)n—) and at least one halomethyl group (—CXH2) and optionally comprising at least one non-fluorine heteroatom, and the halogen being selected from iodine and bromine; wherein the distribution has a number average ratio of methylene moieties of the polymethylene segment to the halomethyl groups of at least about 15.
摘要翻译：组合物包含乙烯和至少一种氟代烷基或全氟烷基卤化物的调聚物的分布，所述调聚物包含至少一个多亚亚乙基链段（ - （CH 2）n - ）和至少一个卤代甲基（-CXH 2），并且任选地包含至少一个非氟杂原子，卤素选自碘和溴; 其中所述分布具有至少约15的多亚甲基部分的亚甲基部分与卤代甲基的数均比例。

13. 发明申请

US20120164031A1 FLUORESCENCE QUENCHING BASED OXYGEN SENSOR 有权
标题翻译：基于荧光猝灭的氧传感器
公开(公告)号：US20120164031A1
公开(公告)日：2012-06-28
申请号：US13308992
申请日：2011-12-01
申请人： Bogdan Catalin Serban , Mihai N. Mihaila , Octavian Buiu
发明人： Bogdan Catalin Serban , Mihai N. Mihaila , Octavian Buiu
IPC分类号： G01N21/64 , C08F112/08 , B32B17/10 , C09D125/06
CPC分类号： G01N21/643 , C08F8/06 , C08F8/10 , C08F8/14 , C08F8/20 , C08F8/24 , C08F12/22 , C08F12/32 , G01N2021/6432 , Y10T428/31645 , C08F112/08
摘要： A fluorescence quenching based oxygen sensor can be prepared comprising a polystyrene polymer linked to pyrene. The fluorescence based sensor has the formula (I), Polystyrene-Y—R-Pyrene (I); wherein Y is fluorescence quenching and R is an aliphatic linking group having 1 to 11 carbon atoms. The sensor can be coated onto a support and integrated with an LED excitation source and fluorescence detector.
摘要翻译：可以制备基于荧光淬灭的氧传感器，其包含与芘连接的聚苯乙烯聚合物。基于荧光的传感器具有式（I），聚苯乙烯-Y-R-芘（I）; 其中Y是荧光淬灭，R是具有1至11个碳原子的脂族连接基团。传感器可以涂覆在支架上并与LED激发源和荧光检测器集成。

14. 发明申请

US20090316085A1 OPTICAL COMPENSATION FILMS OF BROMINATED STYRENIC POLYMERS AND RELATED METHODS 有权
标题翻译：交联苯乙烯聚合物的光学补偿膜及相关方法
公开(公告)号：US20090316085A1
公开(公告)日：2009-12-24
申请号：US12429645
申请日：2009-04-24
申请人： Dong Zhang , Jiaokai Jing , Zhikuan Lu , Thauming Kuo , Brian Michael King , Xiaoliang Zheng , Frank W. Harris , Ted Calvin Germroth
发明人： Dong Zhang , Jiaokai Jing , Zhikuan Lu , Thauming Kuo , Brian Michael King , Xiaoliang Zheng , Frank W. Harris , Ted Calvin Germroth
IPC分类号： G02F1/1335 , B32B5/00 , C08G61/12 , C08K5/00
CPC分类号： G02B1/04 , C08F8/22 , C08J5/18 , C08J2325/18 , G02B5/3016 , G02B5/3083 , G02F1/133634 , G02F1/134363 , Y10T428/31504 , Y10T428/31855 , C08L25/06 , C08F112/08 , C08F8/10
摘要： Some embodiments include compositions and/or methods related to optical compensation films. More particularly, some embodiments can include brominated polystyrene compositions, and/or methods for their preparation, suitable for forming optical compensation films. In some embodiments, suitable brominated polystyrene compositions, and/or methods for their preparation, can include aromatic rings having one or more acyl moieties.
摘要翻译：一些实施例包括与光学补偿膜相关的组合物和/或方法。更具体地，一些实施方案可以包括溴化聚苯乙烯组合物和/或其制备方法，适于形成光学补偿膜。在一些实施方案中，合适的溴化聚苯乙烯组合物和/或其制备方法可包括具有一个或多个酰基部分的芳环。

15. 发明授权

US07635734B2 Photochemical activation of surfaces for attaching biomaterial 有权
标题翻译：用于附着生物材料的表面的光化学活化
公开(公告)号：US07635734B2
公开(公告)日：2009-12-22
申请号：US11250877
申请日：2005-10-14
申请人： Ivan Alferiev , Ilia Fishbein , Michael Chorny , Robert J. Levy , Benjamin Yellen , Darryl Williams
发明人： Ivan Alferiev , Ilia Fishbein , Michael Chorny , Robert J. Levy , Benjamin Yellen , Darryl Williams
IPC分类号： A61K47/48
CPC分类号： C08G63/91 , A61K31/765 , A61K31/785 , A61L27/50 , A61L2400/18 , C07K17/02 , C08F8/10 , C08F8/32 , C08F8/34 , C08F226/02 , C08F271/02 , C08F290/00 , C08F291/00 , C08J7/18 , C08L75/04 , C08F120/06 , C08F126/02
摘要： A water-soluble photo-activatable polymer including: a photo-activatable group adapted to be activated by an irradiation source and to form a covalent bond between the water-soluble photo-activatable polymer and a matrix having at least one carbon; a reactive group adapted to covalently react with a biomaterial for subsequent delivery of the biomaterial to a cell; a hydrophilic group; and a polymer precursor. A composition including a monomolecular layer of the water-soluble photo-activatable polymer and a matrix having at least one carbon, wherein the monomolecular layer is covalently attached to the matrix by a covalent bond between the photo-activatable group and the at least one carbon. The composition further includes a biomaterial having a plurality of active groups, wherein the biomaterial is covalently attached to the monomolecular layer by covalent bonding between the active groups and reactive groups. Also provided is a method for delivery of a biomaterial to a cell.
摘要翻译：一种水溶性可光活化聚合物，其包括：适于被辐照源活化并在所述水溶性可光活化聚合物与具有至少一个碳的基质之间形成共价键的可光致活化基团; 适于与生物材料共价反应的反应性基团，用于随后将生物材料递送至细胞; 亲水基团; 和聚合物前体。一种组合物，其包含水溶性可光活化聚合物的单分子层和具有至少一个碳的基质，其中单分子层通过可光致活化基团和至少一个碳之间的共价键共价连接到基质上。组合物还包括具有多个活性基团的生物材料，其中生物材料通过活性基团和反应性基团之间的共价键共价连接到单分子层上。还提供了将生物材料递送到细胞的方法。

16. 发明授权

US07396883B1 Coated polydivinylbenzene beads 有权
标题翻译：涂布聚二乙烯基苯珠
公开(公告)号：US07396883B1
公开(公告)日：2008-07-08
申请号：US10794791
申请日：2004-03-05
申请人： Howard C. Jordi , Qiding Mi
发明人： Howard C. Jordi , Qiding Mi
IPC分类号： C08F8/18
CPC分类号： B01J20/265 , B01D15/34 , B01J20/28004 , B01J20/28033 , B01J20/28097 , B01J20/286 , B01J20/321 , B01J20/3253 , B01J2220/54 , B01J2220/58 , C08F8/10 , C08F8/22 , C08F8/32 , C08J9/40 , C08F112/36
摘要： The present invention provides novel, polymeric supports, methods of making, and methods of using the supports, that have a fluorinated, amidated surface. The supports include polymeric microbeads, thin layers or membranes, plates, monoliths and the like. The supports are useful as packing materials for normal phase, reverse phase, and size exclusion chromatography, and provide high speed separation of analytes with excellent resolution. The fluorinated, amidated surface may include a composition comprising a plurality of repeating units, for example, having the following structure:
摘要翻译：本发明提供具有氟化的酰胺化表面的新颖的聚合物载体，制备方法和使用载体的方法。载体包括聚合物微珠，薄层或膜，板，整料等。该载体可用作正相，反相和尺寸排阻层析的包装材料，并且以优异的分辨率提供分析物的高速分离。氟化的酰胺化表面可以包括包含多个重复单元的组合物，例如具有以下结构：

17. 发明申请

US20070299210A1 Crosslinked lactam polymers 审中-公开
标题翻译：交联的内酰胺聚合物
公开(公告)号：US20070299210A1
公开(公告)日：2007-12-27
申请号：US11472667
申请日：2006-06-22
申请人： Ankur S. Kulshrestha , Kevin Cooper , Walter R. Laredo
发明人： Ankur S. Kulshrestha , Kevin Cooper , Walter R. Laredo
IPC分类号： C08F126/10
CPC分类号： C08F271/02 , C08F8/00 , C08F8/10 , C08F8/14 , C08F8/30 , C08F283/00 , C08F289/00 , C08F2810/20 , C08G69/48 , C08F126/10
摘要： Crosslinked lactam polymers are disclosed. Specifically, lactam polymers having pendant acrylate groups are crosslinked via a Michael addition type acrylate reactant. The crosslinked lactam polymers are useful in medical and pharmaceutical applications.
摘要翻译：公开了交联的内酰胺聚合物。具体而言，具有丙烯酸侧基的内酰胺聚合物通过迈克尔加成型丙烯酸酯反应物进行交联。交联的内酰胺聚合物可用于医疗和药物应用。

18. 发明申请

US20070053867A1 Polymers and polymer coatings 有权
标题翻译：聚合物和聚合物涂料
公开(公告)号：US20070053867A1
公开(公告)日：2007-03-08
申请号：US11507355
申请日：2006-08-21
申请人： Christopher Ober , Sitaraman Krishnan , Qin Lin
发明人： Christopher Ober , Sitaraman Krishnan , Qin Lin
IPC分类号： A01N25/00 , C08F8/30
CPC分类号： A01N37/12 , A01N37/16 , A01N37/36 , C08F8/00 , C08F8/02 , C08F8/04 , C08F8/08 , C08F8/10 , C08F8/12 , C08F8/18 , C08F8/24 , C08F8/32 , C08F287/00 , C08F297/04 , C08L51/006 , C08L53/02 , C09D5/1637 , C09D5/1668 , C09D151/006 , C09D153/02 , Y10T428/3154 , C08L2666/02 , C08F297/026 , C08F8/14 , C08F8/30 , C08F297/046 , C08F297/02
摘要： The invention provides polymers, methods of preparing polymers, and compositions that include polymers, wherein said polymers include a plurality of two-carbon repeating units in a polymer chain, wherein one or more of the two-carbon repeating units of the polymer chain have a substituent that is covalently bonded to a semifluorinated alkyl ethoxy moiety, and the semifluorinated alkyl ethoxy moiety is attached to the polymer chain substituent through an ester, amide, ketone, carbamate, amine, or other suitable linking group. The polymers can be used to provide antifouling coatings.
摘要翻译：本发明提供聚合物，制备聚合物的方法和包括聚合物的组合物，其中所述聚合物包括聚合物链中的多个二碳重复单元，其中聚合物链中的一个或多个双碳重复单元具有共价键合到半氟代烷基乙氧基部分上的取代基，半氟代烷基乙氧基部分通过酯，酰胺，酮，氨基甲酸酯，胺或其它合适的连接基团连接到聚合物链取代基上。聚合物可用于提供防污涂料。

19. 发明申请

US20060160973A1 Process for production of a vinyl polymer terminated with a group having polymerizable carbon-carbon double bond 审中-公开
标题翻译：用具有可聚合碳 - 碳双键的基团封端的乙烯基聚合物的制备方法
公开(公告)号：US20060160973A1
公开(公告)日：2006-07-20
申请号：US10540061
申请日：2003-12-19
申请人： Hajime Harada , Kenichi Kitano , Yoshiki Nakagawa
发明人： Hajime Harada , Kenichi Kitano , Yoshiki Nakagawa
IPC分类号： C08F118/02
CPC分类号： C08F2/40 , C08F8/26 , C08F2800/20 , C08F2810/30 , C08F2810/40 , C08F8/10 , C08F120/18 , C08F2220/1808
摘要： An object of the present invention is to provide a process for producing a vinyl polymer terminated with a group having a polymerizable carbon-carbon double bond with improved stability of quality. The present invention provides a process for producing a vinyl polymer terminated with a group having a polymerizable carbon-carbon double bond, the process being characterized by adding a stable free radical compound as a polymerization inhibitor. By adding the stable free radical compound during production, it is possible to prevent an increase in viscosity and gelation of the polymer which are due to polymerization reaction of the terminal group having the polymerizable carbon-carbon double bond.
摘要翻译：本发明的目的是提供一种具有可聚合碳 - 碳双键基团的乙烯基聚合物的制造方法，其质量稳定性提高。本发明提供一种用可聚合的碳 - 碳双键封端的乙烯基聚合物的制备方法，该方法的特征在于加入稳定的自由基化合物作为聚合抑制剂。通过在制造中添加稳定的自由基化合物，可以防止由于具有可聚合碳 - 碳双键的端基的聚合反应引起的聚合物的粘度和凝胶化的增加。

20. 发明申请

US20020188072A1 Curable coating composition and coating film forming method 审中-公开
标题翻译：可固化涂料组合物和涂膜成型方法
公开(公告)号：US20020188072A1
公开(公告)日：2002-12-12
申请号：US10105272
申请日：2002-03-26
申请人： NIPPON PAINT CO., LTD.
发明人： Akihiro Kanakura , Takashi Irie , Hiroto Yoneda , Hisaki Tanabe
IPC分类号： C08L067/02
CPC分类号： C08F299/00 , C08F8/10 , C08F8/14 , C08F2800/20 , C08F2810/20 , C08F2810/30 , Y10T428/31938 , C08F2220/283 , C08F220/06
摘要： The present invention is to provide a curable coating composition having much less of a volatile organic component, and being excellent in coating film performance such as durability and scratch resistance, and a coating film forming method using the above curable coating composition capable of suppressing generation of sagging and so on. The present invention is a curable coating composition which comprises (a) a component having an active methylene group and/or an active methine group, (b) a component having a methacrylate group and/or an acrylate group, (c) a Michael reaction catalyst and (d) a photo-polymerization initiator. The present invention also provides a coating film forming method which comprises a step (1) of applying a curable coating on a substrate to be coated and a step (2) including a stage of irradiating with ultraviolet ray and a stage of heating, said curable coating comprising the above curable coating composition.
摘要翻译：本发明提供一种具有少量挥发性有机成分的固化性涂料组合物，并且涂膜性能如耐久性和耐划伤性优异的涂膜成型方法以及使用上述可抑制下垂等。本发明是一种可固化涂料组合物，其包含（a）具有活性亚甲基和/或活性次甲基的组分，（b）具有甲基丙烯酸酯基和/或丙烯酸酯基的组分，（c）迈克尔反应催化剂和（d）光聚合引发剂。本发明还提供了一种涂膜形成方法，其包括将待固化涂层涂覆在待涂布的基底上的步骤（1）和包括用紫外线照射和加热阶段的步骤（2）的步骤（2），所述可固化包含上述可固化涂料组合物的涂料。

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