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11. 发明授权

US09662117B2 Apparatus for controlling flow in a bodily organ 有权
公开(公告)号：US09662117B2
公开(公告)日：2017-05-30
申请号：US12758684
申请日：2010-04-12
申请人： Peter Forsell
发明人： Peter Forsell
IPC分类号： A61B17/12 , A61F2/00 , A61N1/05 , A61N1/36 , A61N1/365 , A61N1/40 , A61F7/02 , A61F2/04
CPC分类号： A61B17/12 , A61F2/0036 , A61F2/004 , A61F7/02 , A61F2002/045 , A61F2250/0002 , A61N1/0509 , A61N1/0551 , A61N1/36007 , A61N1/36564 , A61N1/36578 , A61N1/403
摘要： An apparatus for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ comprises an implantable constriction device for gently constricting (i.e. without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and a stimulation device for stimulating the wall portion of the tissue wall. A control device controls the stimulation device to stimulate the wall portion, as the constriction device constricts the wall portion, to cause contraction of the wall portion constricted by the constriction device to further influence the flow in the lumen. The apparatus can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ. Such an organ may be the esophagus, stomach, intestines, urine bladder, urethra, ureter, renal pelvis, aorta, corpus cavernosum, exit veins of erectile tissue, uterine tube, vas deference or bile duct, or a blood vessel.

12. 发明授权

US09656086B2 Methods and systems for lowering blood pressure through reduction of ventricle filling 有权
公开(公告)号：US09656086B2
公开(公告)日：2017-05-23
申请号：US15143742
申请日：2016-05-02
申请人： BackBeat Medical, Inc.
发明人： Yuval Mika , Darren Sherman , Robert S. Schwartz , Robert A. Van Tassel , Daniel Burkhoff
IPC分类号： A61N1/365 , A61N1/368 , A61N1/36 , A61F2/24
CPC分类号： A61N1/36564 , A61F2/2412 , A61F2/2424 , A61F2250/0013 , A61N1/36117 , A61N1/36514 , A61N1/36528 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3682 , A61N1/3684
摘要： Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.

13. 发明授权

US09649487B2 Enhancing perfusion by contraction 有权
公开(公告)号：US09649487B2
公开(公告)日：2017-05-16
申请号：US13968868
申请日：2013-08-16
申请人： Yossi Gross , Amir Dagan , Yotam Reisner , Offer Glasberg , Nitai Hanani , Gal Ariav
发明人： Yossi Gross , Amir Dagan , Yotam Reisner , Offer Glasberg , Nitai Hanani , Gal Ariav
IPC分类号： A61N1/05 , A61N1/36 , A61F2/82 , A61N1/365
CPC分类号： A61N1/05 , A61F2/82 , A61N1/0514 , A61N1/0521 , A61N1/056 , A61N1/36 , A61N1/36564
摘要： Apparatus and methods are described including a mechanical support element that is placed inside a first vein of a subject. At least one electrode disposed on the mechanical support element is placed inside the first vein, in a vicinity of a site upstream of a bifurcation with a second vein of the subject. A control unit enhances downstream blood flow from the first vein by driving the at least one electrode to divert blood downstream into the second vein by constricting the first vein at the upstream site, by driving the at least one electrode to apply a current to the vicinity of the site. The mechanical support element prevents the first vein from collapsing by providing mechanical support to the vein. Other embodiments are also described.

14. 发明申请

US20170072203A1 Methods and Systems for Treating Cardiac Malfunction 审中-公开
标题翻译：治疗心脏功能障碍的方法与系统
公开(公告)号：US20170072203A1
公开(公告)日：2017-03-16
申请号：US15259282
申请日：2016-09-08
申请人： BackBeat Medical, Inc.
发明人： Yuval Mika , Darren Sherman , Daniel Burkhoff
IPC分类号： A61N1/365 , A61N1/02 , A61N1/05 , A61N1/362
CPC分类号： A61N1/36564 , A61N1/3627 , A61N1/36571 , A61N1/36585 , A61N1/368
摘要： Methods and systems for treating cardiac malfunction are disclosed, which according to an embodiment, may involve delivering a stimulation pattern of stimulation pulses to at least one cardiac chamber of a heart, with at least one of the stimulation pulses having a first stimulation setting configured to reduce at least one of end systolic volume (ESV) and end diastolic volume (EDV) in the heart and at least one of the stimulation pulses having a second stimulation setting different from the first stimulation setting, and with the stimulation pattern being configured to reduce the at least one of end systolic volume (ESV) and end diastolic volume (EDV) by at least 5% and maintain the at least one of end systolic volume (ESV) and end diastolic volume (EDV) on average at such reduced volume for a time period of at least one hour.
摘要翻译：公开了用于治疗心脏失常的方法和系统，根据实施例，该方法和系统可以包括将刺激脉冲的刺激模式递送到心脏的至少一个心室，其中至少一个刺激脉冲具有被配置为减少心脏中的收缩末期容积（ESV）和舒张末期容积（EDV）中的至少一个，并且至少一个刺激脉冲具有不同于第一刺激设置的第二刺激设置，并且刺激模式被配置为减少末端收缩容积（ESV）和舒张末期容积（EDV）中的至少一个至少5％，并且在如此减小的体积下平均维持末端收缩容积（ESV）和舒张末期容积（EDV）中的至少一个，至少一个小时的时间。

15. 发明申请

US20160302673A1 MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE 审中-公开
标题翻译：心脏循环长度和压力测量从脉搏压力测量
公开(公告)号：US20160302673A1
公开(公告)日：2016-10-20
申请号：US15131770
申请日：2016-04-18
申请人： Medtronic, Inc.
发明人： Saul E. Greenhut
IPC分类号： A61B5/0215 , A61N1/365 , A61N1/08 , A61B5/00 , A61M5/172
CPC分类号： A61B5/4839 , A61B5/02108 , A61B5/0215 , A61B5/6869 , A61B5/7239 , A61B5/7246 , A61M5/1723 , A61N1/08 , A61N1/36564
摘要： A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold.
摘要翻译：一种用于监测医疗装置中的心血管压力信号的方法和装置，包括确定感测到的压力信号是否大于第一压力阈值，响应于感测到的压力信号确定压力信号的第一度量大于第一压力信号压力阈值，确定所感测到的压力信号是否大于不等于第一压力阈值的第二压力阈值，响应于所感测的压力信号确定压力信号的第二度量大于第一压力阈值，并且确定收缩压或舒张压中的至少一个，其中基于所述第一度量响应于所述压力信号不大于所述第二阈值来确定所述收缩压或舒张压中的至少一个，并且基于所述第二阈值响应于压力信号大于第二阈值的度量。

16. 发明申请

US20160236000A1 MODULAR ANTITACHYARRHYTHMIA THERAPY SYSTEM 审中-公开
公开(公告)号：US20160236000A1
公开(公告)日：2016-08-18
申请号：US15138734
申请日：2016-04-26
申请人： CARDIAC PACEMAKERS, INC.
发明人： Joseph M. Smith , Richard Milton Dujmovic, JR.
IPC分类号： A61N1/39 , A61N1/365 , A61N1/362 , A61N1/372 , A61N1/375
CPC分类号： A61N1/3962 , A61N1/3605 , A61N1/3621 , A61N1/3622 , A61N1/36514 , A61N1/36564 , A61N1/36585 , A61N1/372 , A61N1/37217 , A61N1/3756 , A61N1/3925 , A61N1/3956 , A61N1/3987
摘要： This document discusses, among other things, a modular antitachyarrhythmia therapy system. In an example, a modular antitachyarrhythmia system includes at least two separate modules that coordinate delivery an antitachyarrhythmia therapy, such as defibrillation therapy. In another example, a modular antitachyarrhythmia therapy system includes a sensing module, an analysis module, and a therapy module.

17. 发明申请

US20160213265A1 METHOD AND APPARATUS TO DETECT ISCHEMIA WITH A PRESSURE SENSOR 审中-公开
标题翻译：用压力传感器检测ISCHEMIA的方法和装置
公开(公告)号：US20160213265A1
公开(公告)日：2016-07-28
申请号：US15090105
申请日：2016-04-04
申请人： Medtronic, Inc.
发明人： Sarah A. Audet , James K. Carney , William J. Combs , Tommy D. Bennett , Barbro M.L. Kjellstrom
IPC分类号： A61B5/0205 , A61B5/00
CPC分类号： A61B5/02055 , A61B5/0215 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61N1/36514 , A61N1/36564 , A61N1/37258
摘要： The present disclosure provides an apparatus and method of detecting ischemia with a pressure sensor. The method can include obtaining a pressure signal and determining a pressure rate of change. The method can also include identifying at least one of impaired relaxation and impaired contractility in order to detect ischemia.
摘要翻译：本公开提供了利用压力传感器检测缺血的装置和方法。该方法可以包括获得压力信号并确定压力变化率。该方法还可以包括鉴定减轻的松弛和受损的收缩力中的至少一种以便检测缺血。

18. 发明授权

US09399138B2 Apparatus and method for programming a pacemaker 有权
标题翻译：用于编程起搏器的装置和方法
公开(公告)号：US09399138B2
公开(公告)日：2016-07-26
申请号：US12297988
申请日：2007-04-20
申请人： Zachary Whinnett , Darrel Francis
发明人： Zachary Whinnett , Darrel Francis
IPC分类号： A61N1/00 , A61N1/362 , A61N1/365 , A61N1/368 , A61N1/372
CPC分类号： A61N1/3627 , A61N1/36564 , A61N1/3682 , A61N1/3688 , A61N1/37235 , A61N1/37264
摘要： A pacemaker programming apparatus for programming a pacemaker in an individual. The apparatus comprises means for determining the sensed-paced difference of the pacemaker in the individual: first testing means for determining the optimum AV delay while the pacemaker is atrially pacing at a raised at a heart rate; and calculation means for calculating the optimum AV delay determined by the first testing means minus the sensed-paced difference.
摘要翻译：一种用于对个体起搏器进行编程的起搏器编程装置。该装置包括用于确定个体起搏器的感觉到的节奏差异的装置：第一测试装置，用于在心脏起搏器以心率升高时起搏起搏时确定最佳AV延迟; 以及计算装置，用于计算由第一测试装置确定的最佳AV延迟减去感测到的节奏差。

19. 发明授权

US09392949B2 Ventricular pacing in cardiac-related applications 有权
标题翻译：心脏相关应用中的心室起搏
公开(公告)号：US09392949B2
公开(公告)日：2016-07-19
申请号：US14433372
申请日：2013-10-02
申请人： XSynchro, Inc.
发明人： Daniel Felipe Ortega , Julio César Spinelli , Maria Paula Bonomini , Luis Dante Barja
IPC分类号： A61B5/04 , A61N1/365 , A61N1/05 , A61B5/0428 , A61B5/0472 , A61N1/368 , A61N1/372 , A61B5/042 , A61B5/0456
CPC分类号： A61N1/3682 , A61B5/04011 , A61B5/04012 , A61B5/04017 , A61B5/042 , A61B5/0428 , A61B5/0456 , A61B5/0472 , A61N1/056 , A61N1/36514 , A61N1/36542 , A61N1/36564 , A61N1/36585 , A61N1/3684 , A61N1/3688 , A61N1/37252 , G16H50/30
摘要： Various aspects of the present disclosure are directed toward an asynchrony index that is related to data of a subject's heart. The asynchrony index includes intra-ventricular or inter-ventricular electrical asynchrony data. The intra-ventricular or inter-ventricular electrical asynchrony data can be specific to a certain subject, and indicative of a different conditions specific to that subject.
摘要翻译：本公开的各个方面针对与受试者心脏的数据相关的异步指数。异步指数包括心室内或心室间电异常数据。心室内或心室间电异常数据可以是特定于某个受试者，并指示与该受试者特异的不同条件。

20. 发明申请

US20160067480A1 DELIVERY SYSTEM FOR CARDIAC PACING 审中-公开
标题翻译： CARDIAC PACING交付系统
公开(公告)号：US20160067480A1
公开(公告)日：2016-03-10
申请号：US14846648
申请日：2015-09-04
申请人： AtaCor Medical, Inc.
发明人： Rick Sanghera , Alan Marcovecchio , Sean McGeehan
IPC分类号： A61N1/05 , A61N1/365
CPC分类号： A61N1/0592 , A61B17/3468 , A61B2017/3482 , A61B2017/3488 , A61B2017/3492 , A61M25/00 , A61M25/06 , A61M2205/587 , A61N1/0504 , A61N1/0587 , A61N1/059 , A61N1/362 , A61N1/365 , A61N1/36542 , A61N1/3655 , A61N1/36564 , A61N1/37211 , A61N1/3752
摘要： A delivery device for installing a medical device in a patient comprising a body portion having a proximal end and a distal end, the distal end having a chisel shaped tip, a receptacle disposed in the distal end of the body portion for receiving a medical device for implanting in the patient, a handle disposed at the proximal end of the body portion for facilitating advancement of the proximal end of the body portion into the patient.
摘要翻译：一种用于在患者中安装医疗装置的输送装置，包括具有近端和远端的主体部分，所述远端具有凿子形尖端，设置在主体部分的远端中的接收器，用于接收用于植入患者体内，设置在主体部分的近端处的手柄，用于促进身体部分的近端进入患者体内。

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