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11. 外观设计

USD827313S1 Fabric swatch 有权
公开(公告)号：USD827313S1
公开(公告)日：2018-09-04
申请号：US29641258
申请日：2018-03-20
申请人： Edward Eng , Fang Fang
设计人： Edward Eng , Fang Fang

12. 发明授权

US08586712B2 Humanized antibodies 失效
公开(公告)号：US08586712B2
公开(公告)日：2013-11-19
申请号：US12748304
申请日：2010-03-26
申请人： Fang Fang , Lori Kohlstaedt , John Reno
发明人： Fang Fang , Lori Kohlstaedt , John Reno
IPC分类号： C07K16/28 , C12N15/13 , C12N15/63 , A61K39/395
CPC分类号： C07K16/2896 , A61K2039/505 , C07K16/2821 , C07K2317/24 , C07K2317/622 , C07K2317/92 , C07K2319/00 , Y02A50/412
摘要： Humanized antibodies that bind ICAM-1 are provided. Antibodies include those selected from: SEQ ID NO:1 and 3 (HumA); SEQ ID NO:5 and 7 (HumB); SEQ ID NO:9 and 11 (HumC); SEQ ID NO:13 and 15 (HumD); SEQ ID NO:17 and 19 (HumE); SEQ ID NO:21 and 23 (HumF); SEQ ID NO:25 and 27 (HumG); SEQ ID NO:29 and 31 (HumH); and SEQ ID NO:33 and 35 (HumI). Subsequences of the humanized antibodies capable of binding an ICAM-1 epitope are also provided. Methods of inhibiting pathogen infection (e.g., HRV) of a cell employing humanized antibodies capable of binding an ICAM-1 epitope are further provided.

13. 发明授权

US08394771B1 Multimeric proteins and methods of making and using same 失效
公开(公告)号：US08394771B1
公开(公告)日：2013-03-12
申请号：US11866960
申请日：2007-10-03
申请人： Fang Fang , Guang-Xiang Luo , Lori Allison Kohlstaedt , Catherine Helen Charles
发明人： Fang Fang , Guang-Xiang Luo , Lori Allison Kohlstaedt , Catherine Helen Charles
IPC分类号： A61K38/17 , C12P21/04 , C07K14/435
CPC分类号： C07K16/2821 , A61K38/00 , C07K14/001 , C07K14/4705 , C07K2319/00 , C07K2319/02 , C07K2319/73 , C12N15/62
摘要： The invention provides multimerization polypeptides capable of conferring formation of multimers when the multimerization polypeptide is linked to a molecule, such as a heterologous polypeptide sequence.

14. 发明申请

US20120249441A1 TOUCH PANEL AND METHOD OF MANUFACTURING A TOUCH PANEL 有权
标题翻译：触控面板和制造触控面板的方法
公开(公告)号：US20120249441A1
公开(公告)日：2012-10-04
申请号：US13311556
申请日：2011-12-06
申请人： YUH-WEN LEE , Ching-Shan Lin , Lichun yang , Fang Fang
发明人： YUH-WEN LEE , Ching-Shan Lin , Lichun yang , Fang Fang
IPC分类号： G06F3/041 , B05D5/00
CPC分类号： G06F3/044 , G06F2203/04103
摘要： The present invention discloses a touch panel and a method of manufacturing a touch panel, to reduce the visibility of the transparent etching line of the transparent electrodes on the touch panel. The touch panel comprises a plurality of transparent electrode disposed distantly on the transparent conductive layer and the passivation layer of a transparent substrate, where the passivation layer covering the transparent conductive layer, to make the refractive index of the passivation layer and the transparent electrodes match with each other. Oxide with high refractive index added in the passivation material is filled in the etched area of the transparent conductive layer, so that the optical refractive index of the etched area and ITO area on transparent conductive layer become closer, and the difference in refractive index curve between ITO area and etched area is reduced, therefore, the effect of making the transparent electrode pattern is achieved.
摘要翻译：本发明公开了触摸面板和制造触摸面板的方法，以降低触摸面板上的透明电极的透明蚀刻线的可视性。触摸面板包括多个透明电极，其设置在透明导电层上的透明电极和透明衬底的钝化层，其中钝化层覆盖透明导电层，以使钝化层和透明电极的折射率与彼此。在钝化材料中加入高折射率的氧化物被填充在透明导电层的蚀刻区域中，使得透明导电层上的蚀刻区域和ITO区域的光学折射率变得更接近，并且折射率之间的折射率差 ITO区域和蚀刻面积减少，因此，实现了形成透明电极图案的效果。

15. 发明授权

US08262283B2 Apparatus and method for determining the thermal stability of fluids 有权
标题翻译：用于确定流体热稳定性的装置和方法
公开(公告)号：US08262283B2
公开(公告)日：2012-09-11
申请号：US12838104
申请日：2010-07-16
申请人： Guoxing Yang , David G. Anderson , Larry M. Youngblood , Fang Fang , Sean E. Rick , Larry A. Spino , Scott K. Berkhous
发明人： Guoxing Yang , David G. Anderson , Larry M. Youngblood , Fang Fang , Sean E. Rick , Larry A. Spino , Scott K. Berkhous
IPC分类号： G01N33/22 , G01N25/00
CPC分类号： G01N33/2805
摘要： A thermal oxidation tester is shown for determining thermal stability of a fluid, particularly hydrocarbons when subjected to elevated temperatures. The tendency of the heated fluid to oxidize and (1) form deposits on a surface of a heater tube and (2) form solids therein, are both measured at a given flow rate, temperature and time. The measured results are used to determine whether a fluid sample passes or fails the test. Results of measurements are recorded in a memory device on one end of the heater tube on which the deposits were made.
摘要翻译：示出了热氧化测试仪，用于确定流体，特别是当受到升高的温度时的烃的热稳定性。加热的流体氧化的趋势和（1）在加热器管的表面上形成沉积物，和（2）在其中形成固体，都是在给定的流速，温度和时间下测量的。测量结果用于确定流体样品是否通过或未通过测试。测量结果记录在其上形成沉积物的加热器管的一端上的存储器件中。

16. 发明申请

US20110171132A1 Methods, Compounds, and Compositions for Treatment and Prophylaxis in the Respiratory Tract 有权
标题翻译：方法，化合物和组合物在呼吸道中的治疗和预防
公开(公告)号：US20110171132A1
公开(公告)日：2011-07-14
申请号：US12940742
申请日：2010-11-05
申请人： Fang Fang , David Wurtman , Ron Moss , Michael P. Malakhov
发明人： Fang Fang , David Wurtman , Ron Moss , Michael P. Malakhov
IPC分类号： A61K49/00 , A61K38/47 , C12Q1/02 , A61P11/12
CPC分类号： A61K38/47 , A61K9/0014 , A61K9/0019 , A61K9/0043 , A61K9/0053 , A61K9/0073 , A61K9/06 , A61K31/05 , A61K31/198 , A61K31/4172 , A61K31/7016 , A61K33/06 , A61K33/14 , A61K38/1808 , A61K45/06 , A61K47/02 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34 , A61K49/0008 , C07K14/485 , C07K2319/00 , C12N9/2402 , C12N9/2477 , C12Q1/34 , C12Y302/01018 , G01N2500/00 , G01N2800/122 , A61K2300/00
摘要： The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.
摘要翻译：本发明提供一种减少所述呼吸道中粘液水平升高的受试者呼吸道中的粘液的量的方法。该方法包括向受试者施用含有治疗有效量的包含唾液酸酶或其活性部分和锚定结构域的融合蛋白的化合物或组合物。治疗有效量包括与施用化合物或组合物之前存在的粘液的量相比，在施用化合物或组合物之后导致呼吸道中的粘液数量减少的量的融合蛋白。

17. 发明申请

US20100166874A1 Technology for Preparation of Macromolecular Microspheres 审中-公开
标题翻译：高分子微球制备技术
公开(公告)号：US20100166874A1
公开(公告)日：2010-07-01
申请号：US12633773
申请日：2009-12-08
申请人： Michael P. Malakhov , Fang Fang
发明人： Michael P. Malakhov , Fang Fang
IPC分类号： A61K38/43 , A61K9/14 , A61K39/00 , A61K38/16 , A61K31/7088 , A61K31/715 , A61K31/56 , A61K47/42 , A61P3/10 , A61P25/16 , A61P29/00 , A61P23/00 , A61P33/06 , A61P31/04 , A61P35/00 , A61P3/02
CPC分类号： A61K9/1682 , A61K9/0073 , A61K9/14 , A61K9/1617 , A61K9/1647 , A61K9/19 , A61K38/18 , A61K38/47 , A61K38/57 , C12Y302/01018 , Y02A50/385 , Y02A50/387 , Y02A50/393 , Y02A50/401 , Y02A50/402 , Y02A50/411 , Y02A50/469 , Y02A50/47 , Y02A50/471 , Y02A50/478 , Y02A50/48 , Y02A50/483 , Y02A50/491 , Y10T428/2982
摘要： Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions.
摘要翻译：通过使蛋白质或其他高分子的水溶液与有机溶剂和抗衡离子接触并冷却溶液来制备微球体。微球可用于制备具有限定尺寸的药物。

18. 发明申请

US20050004020A1 Broad spectrum anti-viral therapeutics and prophylaxis 有权
标题翻译：广谱抗病毒治疗和预防
公开(公告)号：US20050004020A1
公开(公告)日：2005-01-06
申请号：US10718986
申请日：2003-11-21
申请人： Mang Yu , Fang Fang
发明人： Mang Yu , Fang Fang
IPC分类号： A61K20060101 , A61K38/16 , A61K38/17 , A61K38/47 , A61K38/48 , A61K38/55 , A61K38/56 , A61K38/57 , A61K39/00 , A61K47/48
CPC分类号： B82Y5/00 , A61K38/47 , A61K38/57
摘要： The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of the target cell by a pathogen, such as a virus. Preferred target cells are epithelial cells. The invention provides compositions and methods for preventing viral diseases, such as influenza, using compounds having anchoring domains that can bind target cells linked to enzymatic activities that can act extracellularly to interfere with viral infection of target cells. The invention also provides compositions and methods for preventing viral diseases such as influenza using compounds having anchoring domains that can bind target cells linked to protease inhibitors that can act extracellularly to interfere with viral infection of target cells.
摘要翻译：本发明提供了用于预防和治疗病原体感染的新的组合物和方法。特别地，本发明提供具有将化合物锚定在靶细胞表面的锚定结构域的化合物，以及可以在细胞外作用以防止病原体如病毒感染靶细胞的治疗结构域。优选的靶细胞是上皮细胞。本发明提供了用于预防病毒性疾病（例如流行性感冒）的组合物和方法，使用具有锚定结构域的化合物，所述化合物具有可结合与细胞外作用以干扰靶细胞的病毒感染的酶活性连接的靶细胞。本发明还提供了用于使用具有锚定结构域的化合物来预防病毒性疾病例如流感的组合物和方法，所述化合物具有可以结合与蛋白酶抑制剂连接的靶细胞，其可以在细胞外作用以干扰靶细胞的病毒感染。

19. 外观设计

USD911039S1 Fabric 有权
公开(公告)号：USD911039S1
公开(公告)日：2021-02-23
申请号：US29706966
申请日：2019-09-25
申请人： Edward Eng , Fang Fang
设计人： Edward Eng , Fang Fang

20. 外观设计

USD866197S1 Fabric swatch 有权
公开(公告)号：USD866197S1
公开(公告)日：2019-11-12
申请号：US29659228
申请日：2018-08-07
申请人： Edward Eng , Fang Fang
设计人： Edward Eng , Fang Fang
摘要： FIG. 1 is a front isometric view of the fabric swatch showing our new invention;
FIG. 2 is a front view thereof;
FIG. 3 is a rear view thereof;
FIG. 4 is a top plan view thereof, the bottom plan view being a mirror image thereof;
FIG. 5 is a right side view thereof, the left side view being a mirror image thereof; and,
FIG. 6 is an enlarged isometric view of area 6 circled within FIG. 1.
The broken lines on the outside edges of the drawings and the edges surrounding the recessed areas within the article depict portions of the fabric swatch that form no part of the claimed design. The broken line circumscribing the area labeled 6 within FIG. 1 and surrounding FIG. 6 indicate the area of the enlarged detail and form no part of the claimed design.

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