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11. 发明授权

US07547383B2 Biosensor and method 有权
标题翻译：生物传感器和方法
公开(公告)号：US07547383B2
公开(公告)日：2009-06-16
申请号：US10861670
申请日：2004-06-04
申请人： Xiaohua Cai , Handani Winarta , Chung Chang Young
发明人： Xiaohua Cai , Handani Winarta , Chung Chang Young
IPC分类号： G01N27/327
CPC分类号： C12Q1/34 , C12Q1/004 , C12Q1/006 , C12Q1/26 , C12Q1/28 , Y10T29/49002
摘要： An improved biosensor having at least a first working electrode and a first electrode material disposed on the first working electrode. The first electrode material is a mixture made by combining at least one enzyme where the at least one enzyme is a capable of reacting with the analyte to be measured, a redox mediator capable of reacting with a product of an enzymatic reaction or a series of enzymatic reactions involving the at least one enzyme, a peroxidase capable of catalyzing a reaction involving the redox mediator where the redox mediator is oxidized, a binder and a surfactant.
摘要翻译：一种改进的生物传感器，具有至少第一工作电极和设置在第一工作电极上的第一电极材料。第一电极材料是通过将至少一种酶与待测分析物反应的至少一种酶，能够与酶反应或一系列酶反应的产物反应的氧化还原介体涉及至少一种酶的反应物，能够催化涉及氧化还原介体被氧化的氧化还原介体的反应的过氧化物酶，粘合剂和表面活性剂。

12. 发明授权

US06942770B2 Disposable sub-microliter volume biosensor with enhanced sample inlet 有权
标题翻译：具有增强的样品入口的一次性亚微升体积生物传感器
公开(公告)号：US06942770B2
公开(公告)日：2005-09-13
申请号：US10126818
申请日：2002-04-19
申请人： Xiaohua Cai , Handani Winarta , Andy Vo , Chung Chang Young
发明人： Xiaohua Cai , Handani Winarta , Andy Vo , Chung Chang Young
IPC分类号： G01N27/327 , C12M1/34 , C12Q1/00 , G01N27/30 , G01N27/416 , G01N33/487
CPC分类号： C12Q1/001 , G01N27/3272
摘要： A disposable electrode strip for testing a fluid sample including a laminated strip with a first and second end, a vent, an open path for receiving a fluid sample of less than one microliter beginning from the first end and connecting to the vent, a working electrode, a reference electrode and a pseudo-working electrode embedded in the laminated strip within the open path and proximate to the first end, a reagent matrix coextensive within the open path and covering the three electrodes, and conductive contacts located at the second end of the laminated strip.
摘要翻译：一种用于测试流体样品的一次性电极条，包括具有第一和第二端的层压条，通气口，用于接收从第一端开始并连接到通风口的小于1微升的流体样品的开放路径，工作电极，参考电极和伪工作电极，其嵌入在开放路径内并且靠近第一端的层压条中，在开放路径内共同延伸并覆盖三个电极的试剂基体和位于第二端的导电触点层压带。

13. 发明授权

US07955484B2 Glucose biosensor and method 有权
标题翻译：葡萄糖生物传感器和方法
公开(公告)号：US07955484B2
公开(公告)日：2011-06-07
申请号：US11306005
申请日：2005-12-14
申请人： Xiaohua Cai , Chung Chang Young , Jianhong Pei , Andy Vo
发明人： Xiaohua Cai , Chung Chang Young , Jianhong Pei , Andy Vo
IPC分类号： G01N27/327 , G01N27/416
CPC分类号： C12Q1/006 , G01N33/66
摘要： A system for more accurately measuring glucose in a sample includes a first glucose-sensing electrode incorporating a quantity of glucose oxidase, a second glucose-sensing electrode incorporating a quantity of PQQ-glucose dehydrogenase, a reference electrode, and means for selecting between a first glucose measurement made with the first glucose-sensing electrode and a second glucose measurement made with the second glucose-sensing electrode.
摘要翻译：用于更准确地测量样品中的葡萄糖的系统包括掺入一定数量的葡萄糖氧化酶的第一葡萄糖感测电极，掺入一定数量的PQQ-葡萄糖脱氢酶的第二葡萄糖感测电极，参比电极和用于在第一用第一葡萄糖感测电极进行葡萄糖测量，并用第二葡萄糖感测电极进行第二葡萄糖测量。

14. 发明申请

US20090223834A1 Biosensor and method 审中-公开
标题翻译：生物传感器和方法
公开(公告)号：US20090223834A1
公开(公告)日：2009-09-10
申请号：US12466767
申请日：2009-05-15
申请人： Xiaohua Cai , Handani Winarta , Chung Chang Young
发明人： Xiaohua Cai , Handani Winarta , Chung Chang Young
IPC分类号： G01N27/26
CPC分类号： C12Q1/34 , C12Q1/004 , C12Q1/006 , C12Q1/26 , C12Q1/28 , Y10T29/49002
摘要： A method of compensating for the presence of hematocrit in a blood sample when measuring a blood analyte using a disposable sensor strip. The method includes disposing a blood sample onto a working electrode and a reference electrode of the disposable sensor strip to obtain a concentration of an analyte in the blood sample, measuring a resistance value of the blood sample between the reference electrode and the working electrode, and calculating a corrected concentration of the analyte using the resistance value and a hematocrit equation to correct for the presence of hematocrit in the blood sample.
摘要翻译：当使用一次性传感器条测量血液分析物时，补偿血液样品中血细胞比容存在的方法。该方法包括将血液样本设置在一次性传感器条的工作电极和参考电极上，以获得血液样品中的分析物的浓度，测量参考电极和工作电极之间的血液样本的电阻值，以及使用电阻值和血细胞比容方程计算校正的分析物浓度以校正血液样品中血细胞比容的存在。

15. 发明授权

US06287451B1 Disposable sensor and method of making 有权
标题翻译：一次性传感器及其制作方法
公开(公告)号：US06287451B1
公开(公告)日：2001-09-11
申请号：US09324443
申请日：1999-06-02
申请人： Handani Winarta , Xiaohua Cai , Fung Seto , Chung Chang Young
发明人： Handani Winarta , Xiaohua Cai , Fung Seto , Chung Chang Young
IPC分类号： G01N2726
CPC分类号： C12Q1/002
摘要： A disposable electrode strip for testing a fluid sample including a laminated strip with a first and second end, a reference electrode embedded in the laminated strip proximate to the first end, at least two working electrodes embedded in the laminated strip proximate to the first end and the reference electrode, an open path for receiving a fluid sample beginning from the first end and being sufficiently long to expose the reference electrode and the working electrodes to the fluid sample, and conductive contacts located at the second end of the laminated strip. The laminated strip has a base layer with a conductive coating, a reagent holding layer, a channel forming layer and a cover. One of the working electrodes contains a reagent substantially similar to the reagent of the reference electrode and a second working electrode contains a reagent having an enzyme.
摘要翻译：一种用于测试流体样品的一次性电极条，包括具有第一和第二端的层压条，附接到第一端的层压条中的参考电极，嵌入层叠带中的至少两个工作电极，靠近第一端，参考电极，用于从第一端开始接收流体样品并且足够长以将参考电极和工作电极暴露于流体样品的开放路径，以及位于层压条的第二端处的导电触点。层叠带具有带有导电涂层的底层，试剂保持层，通道形成层和盖。其中一个工作电极含有与参考电极的试剂基本相似的试剂，第二工作电极含有具有酶的试剂。

16. 发明申请

US20150233861A1 TEST SENSOR WITH MULTIPLE SAMPLING ROUTES 审中-公开
标题翻译：具有多个采样路径的测试传感器
公开(公告)号：US20150233861A1
公开(公告)日：2015-08-20
申请号：US14184764
申请日：2014-02-20
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： An improved disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The novel extra wide sampling entrance of the test sensor provided by the present invention can draw blood into the chamber not only from the front of the sampling entrance as usual in convenient sensors, but also from the top, bottom, left corner and right corner of the sampling entrance. Thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
摘要翻译：改进的一次性电化学测试传感器设计用于方便采样液体样品。它具有流体室，具有新颖的超宽采样入口。该室提供储存器，通过毛细管作用，样品流体可从该储存器吸入室中。本发明提供的测试传感器的新颖的超宽采样入口，不仅可以像往常一样在便利的传感器中从血液进入采样入口的前方，还可以从上，下，左，抽样入口。因此，它允许容易地对具有小体积的样品进行定位，拾取涂抹的样品，并且对于将传感器的尖端堵塞到用户手指中的用户更容忍。

17. 发明申请

US20150198554A1 DISPOSABLE TEST SENSOR 有权
标题翻译：不可测试的传感器
公开(公告)号：US20150198554A1
公开(公告)日：2015-07-16
申请号：US14153654
申请日：2014-01-13
申请人： Xiaohua Cai , Hongli Che , Shaobo Li
发明人： Xiaohua Cai , Hongli Che , Shaobo Li
IPC分类号： G01N27/327
CPC分类号： G01N27/3272
摘要： The present invention relates to disposable test sensors having improved sample application and measuring properties and their uses for detection, preferably, quantitative measurement, of analyte in a liquid sample like blood. In particular, the invention provides for an electrochemical biosensor which has a thin-layer fluid chamber having funnel-like shape with a novel extra wide opening as sampling entrance and a vent opening at the tip of the chamber for air escape. The thin-layer fluid chamber provides a reservoir from which a sample fluid can be drawn into it through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
摘要翻译：本发明涉及一次性测试传感器，其具有改进的样品应用和测量性质及其用于检测，优选地定量测量液体样品（例如血液）中的分析物的用途。特别地，本发明提供了一种电化学生物传感器，其具有具有漏斗状形状的薄层流体室，其具有作为取样入口的新颖的宽敞开口，并且在室的顶部具有用于空气逸出的通风口。薄层流体室提供储存器，通过毛细管作用可将样品流体从该储存器吸入。本发明提供的超宽采样入口可以通过开口的任何部分将血液吸入腔室，从而容易地以小体积对准样品，拾取涂抹样品，并且对于堵塞尖端的使用者更容忍传感器进入用户的手指。

18. 发明授权

US07805597B2 Parallel link reset in link based system 有权
标题翻译：基于链路的系统并行链路复位
公开(公告)号：US07805597B2
公开(公告)日：2010-09-28
申请号：US11731064
申请日：2007-03-30
申请人： Xiaohua Cai , Yufu Li , Zhijun Liu , Geng Tian
发明人： Xiaohua Cai , Yufu Li , Zhijun Liu , Geng Tian
IPC分类号： G06F9/00 , G06F9/24 , G06F15/177
CPC分类号： G06F15/16
摘要： A link based system including a plurality of processors is reset when transitioning from a slower speed to a higher speed mode during a booting process. One processor may coordinate the simultaneous establishment of link resetting of a plurality of other processors. In one embodiment, the processors may operate beginning with the farthest processor to reset their local links. Each processor sets its local links and if it determines, based on the speed of the link that the link has already been reset, it moves on to the next link.
摘要翻译：包括多个处理器的基于链路的系统在引导过程期间从较慢速度转换到较高速度模式时被复位。一个处理器可以协调同时建立多个其他处理器的链路重置。在一个实施例中，处理器可以从最远的处理器开始操作以重置其本地链路。每个处理器设置其本地链路，并且如果它根据链路已经被重置的链路的速度来确定它移动到下一个链路。

19. 发明申请

US20070023296A1 Oxygen Sensor 有权
标题翻译：氧传感器
公开(公告)号：US20070023296A1
公开(公告)日：2007-02-01
申请号：US11161180
申请日：2005-07-26
申请人： Xiaohua Cai , Kara Alesi , Chung Young
发明人： Xiaohua Cai , Kara Alesi , Chung Young
IPC分类号： G01N27/26 , G01F1/64
CPC分类号： G01N27/3272
摘要： An oxygen sensor has a laminated body with a fluid sample inlet end and an electrical contact end, a fluid sample inlet, a substantially flat test chamber communicating with the fluid sample inlet where the test chamber is adapted to collect a fluid sample through the sample fluid inlet, a working electrode and a reference electrode within the test chamber, and a reagent matrix disposed on the working electrode where the reagent matrix contains an oxidase, a reduced form of a redox mediator and a peroxidase.
摘要翻译：氧传感器具有层流体，其具有流体样品入口端和电接触端，流体样品入口，与流体样品入口连通的基本平坦的测试室，其中测试室适于通过样品流体收集流体样品入口，测试室内的工作电极和参比电极，以及设置在工作电极上的试剂基质，其中试剂基质含有氧化酶，还原形式的氧化还原介体和过氧化物酶。

20. 发明授权

US07936703B2 Optimized cache consistency algorithm in a point-to-point interconnected multiple processor system 有权
标题翻译：在点对点互连多处理器系统中优化缓存一致性算法
公开(公告)号：US07936703B2
公开(公告)日：2011-05-03
申请号：US11995047
申请日：2006-09-20
申请人： Yufu Li , Xiaohua Cai
发明人： Yufu Li , Xiaohua Cai
IPC分类号： H04L12/28
CPC分类号： G06F12/0831
摘要： A spanning tree is assigned to a processing node for each processing node in a point-to-point network that connects a plurality of processing nodes. The spanning tree uses the processing nodes as vertices and links of the network as edges. Each processing node includes input snoop ports that can be configured as either terminating or forwarding. According to the assigned spanning trees and the configuration of the input snoop ports, the network routes snoop messages efficiently and without conflicts.
摘要翻译：生成树被分配给连接多个处理节点的点对点网络中的每个处理节点的处理节点。生成树使用处理节点作为边缘的网络的顶点和链接。每个处理节点包括可配置为终止或转发的输入侦听端口。根据分配的生成树和输入snoop端口的配置，网络可以有效且无冲突地发送snoop报文。

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