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11. 发明申请

US20130202080A1 System and Method for Denoising Medical Images Adaptive to Local Noise 有权
标题翻译：用于去噪局部噪声的医学图像的系统和方法
公开(公告)号：US20130202080A1
公开(公告)日：2013-08-08
申请号：US13762141
申请日：2013-02-07
申请人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
发明人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： G06T11/003 , A61B6/032 , A61B6/5205 , A61B6/5258 , A61B6/542 , A61B6/583
摘要： A system and method is provided for estimating the local noise of CT images and denoising the images using a modified non-local means (NLM) algorithm that is adaptive to local variations of noise levels. A strategy for efficiently estimating the local noise of CT images is also described.
摘要翻译：提供了一种用于估计CT图像的局部噪声并使用适应于噪声水平的局部变化的修改的非局部平均（NLM）算法去噪图像的系统和方法。还描述了用于有效估计CT图像的局部噪声的策略。

12. 发明申请

US20120114093A1 System and Method for Automatic Tube Potential Selection for Dose Reduction in Medical Imaging 有权
标题翻译：自动管电位选择用于医学成像降低剂量的系统和方法
公开(公告)号：US20120114093A1
公开(公告)日：2012-05-10
申请号：US13384454
申请日：2010-07-15
申请人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.
摘要翻译：一种用于CT成像的方法，其利用针对个体对象和诊断任务的自动管电位选择。该方法量化不同管电位的相对辐射剂量以实现特定的图像质量。这允许选择提供减小的辐射剂量的管电位，同时仍然提供足够质量的CT图像。

13. 发明申请

US20110286651A1 Projection-Space Denoising with Bilateral Filtering in Computed Tomography 有权
标题翻译：计算机断层扫描中双边滤波的投影空间去噪
公开(公告)号：US20110286651A1
公开(公告)日：2011-11-24
申请号：US13145461
申请日：2010-02-19
申请人： Lifeng Yu , Armando Manduca , Joshua Tizasko , Joel G. Fletcher
发明人： Lifeng Yu , Armando Manduca , Joshua Tizasko , Joel G. Fletcher
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T2207/20028
摘要： Projection data acquired with an x-ray CT system is filtered using a bilateral filter to reduce image noise and enable the acquisition at lower x-ray dose without the loss of image diagnostic quality. The bilateral filtering is performed before image reconstruction by producing a noise equivalent data set from the acquired projection data and then converting the bilateral filtered values back to a projection data set suitable for image reconstruction.
摘要翻译：用x射线CT系统获取的投影数据使用双边滤波器进行滤波，以降低图像噪声，并能够在较低X射线剂量下进行采集，而不会损失图像诊断质量。通过从获取的投影数据产生噪声等效数据集，然后将双边滤波值转换回适合于图像重建的投影数据集，在图像重构之前执行双边滤波。

14. 发明授权

US07885373B2 System and method for quantitative imaging of chemical composition to decompose multiple materials 有权
标题翻译：用于化学成分定量成像分解多种材料的系统和方法
公开(公告)号：US07885373B2
公开(公告)日：2011-02-08
申请号：US12371433
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： H05G1/60
CPC分类号： A61B6/482 , A61B5/4869 , A61B6/032 , A61B6/4014 , A61B6/4241
摘要： The present invention provides a material decomposition method capable of determining the distribution of density and constituent material concentration throughout an imaged object. The concentration, in the form of a mass fraction, mass percent, weight fraction, or weight percent, is determined from CT images acquired at different energy levels. The ratio of attenuation coefficients associated with one energy level to attenuation coefficients associated with another energy level is determined and used as an index in a lookup table to determine the concentration of a given material throughout the imaged object.
摘要翻译：本发明提供一种能够确定整个成像对象的密度和构成材料浓度分布的材料分解方法。以不同能级获得的CT图像确定以质量分数形式的质量百分比，重量分数或重量百分比的浓度。确定与一个能级相关联的衰减系数与与另一能级相关联的衰减系数的比率，并将其用作查找表中的索引，以确定整个成像对象中给定材料的浓度。

15. 发明授权

US08965078B2 Projection-space denoising with bilateral filtering in computed tomography 有权
标题翻译：计算机断层扫描中双边滤波的投影空间去噪
公开(公告)号：US08965078B2
公开(公告)日：2015-02-24
申请号：US13145461
申请日：2010-02-19
申请人： Lifeng Yu , Armando Manduca , Joshua Trzasko , Joel G. Fletcher
发明人： Lifeng Yu , Armando Manduca , Joshua Trzasko , Joel G. Fletcher
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/005 , G06T2207/20028
摘要： Projection data acquired with an x-ray CT system is filtered using a bilateral filter to reduce image noise and enable the acquisition at lower x-ray dose without the loss of image diagnostic quality. The bilateral filtering is performed before image reconstruction by producing a noise equivalent data set from the acquired projection data and then converting the bilateral filtered values back to a projection data set suitable for image reconstruction.
摘要翻译：用x射线CT系统获取的投影数据使用双边滤波器进行滤波，以降低图像噪声，并能够在较低X射线剂量下进行采集，而不会损失图像诊断质量。通过从获取的投影数据产生噪声等效数据集，然后将双边滤波值转换回适合于图像重建的投影数据集，在图像重构之前执行双边滤波。

16. 发明授权

US08903037B2 System and method for automatic tube potential selection for dose reduction in medical imaging 有权
公开(公告)号：US08903037B2
公开(公告)日：2014-12-02
申请号：US14183639
申请日：2014-02-19
申请人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.

17. 发明授权

US08280135B2 System and method for highly attenuating material artifact reduction in x-ray computed tomography 有权
标题翻译： X射线计算机断层扫描中高度衰减材料伪影减少的系统和方法
公开(公告)号：US08280135B2
公开(公告)日：2012-10-02
申请号：US12690765
申请日：2010-01-20
申请人： Cynthia H McCollough , Lifeng Yu
发明人： Cynthia H McCollough , Lifeng Yu
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/12 , A61B6/5258 , G06T5/005 , G06T7/13 , G06T11/005 , G06T2207/10081 , G06T2207/20036 , G06T2207/30004
摘要： The present invention is a method for reducing artifacts caused by highly attenuating materials in x-ray computed tomography (“CT”) images. The method includes combining projection views acquired at equivalent view angles to generate a projection plane data set, from which a reformatted projection is produced. The reformatted projection is then processed to detect and segment regions corresponding to objects composed of metals, metal alloys, or other highly attenuating materials. These segmented regions are then removed from the reformatted projection and the removed portions replaced by attenuation information interpolated from portions of the reformatted projection adjacent the removed portions. The interpolated reformatted projection is then mapped back to a projection plane data set, and an image of the subject is reconstructed from the projection views contained in that data set. The reconstructed image, therefore, is one in which artifacts caused by highly attenuating materials are substantially suppressed.
摘要翻译：本发明是一种减少由X射线计算机断层摄影（CT）图像中的高衰减材料引起的假象的方法。该方法包括组合以等同视角获得的投影视图，以产生投影平面数据集，从该投影平面数据集中产生重新格式化的投影。然后对重新格式化的投影进行处理以检测和分割对应于由金属，金属合金或其它高度衰减材料组成的物体的区域。然后将这些分段区域从重新格式化的突起中移除，并且将去除的部分替换为与邻近去除部分的重新格式化突起的部分内插的衰减信息。然后将内插的重新格式化的投影映射回到投影平面数据集，并且从包含在该数据集中的投影视图重建对象的图像。因此，重建的图像是其中由高度衰减的材料引起的伪像被基本抑制的图像。

18. 发明申请

US20110188725A1 METHOD FOR RECONSTRUCTION IN DUAL ENERGY, DUAL SOURCE HELICAL COMPUTED TOMOGRAPHY 有权
标题翻译：双能重建方法，双源螺旋计算机图
公开(公告)号：US20110188725A1
公开(公告)日：2011-08-04
申请号：US13059579
申请日：2009-09-02
申请人： Lifeng Yu , Cynthia H. Mccollough
发明人： Lifeng Yu , Cynthia H. Mccollough
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/408
摘要： A system and method for the accurate quantitative evaluation of dual-energy computed tomography (CT) projection data that is acquired in a dual-source helical scan includes employing a dual-source z-axis helical interpolation method. The method includes transforming the two helical projection data sets, where corresponding projections of high- and low-energy data sets are shifted with respect to one another by 90 degrees or another angle, into corresponding non-helical projection data sets. A dual-source helical interpolation algorithm allows for projection space dual-energy processing by realigning the high- and low-energy datasets based on the z-axis interpolation. This algorithm may be implemented using a variety of interpolation schemes and can be extended from single slice to multi-slice data acquisitions. Subsequent to the registration of the non-helical projection data sets, projection space processing allows for accurate material quantification and virtual monochromatic images in which beam hardening artifacts have been substantially suppressed.
摘要翻译：用于在双源螺旋扫描中获取的双能量计算机断层摄影（CT）投影数据的精确定量评估的系统和方法包括采用双源z轴螺旋插值方法。该方法包括对两个螺旋投影数据集进行变换，其中高能数据集和低能数据集的相应投影相对于彼此偏移了90度或另一个角度，转换为相应的非螺旋投影数据集。双源螺旋插值算法允许通过基于z轴插值重新对齐高能量和低能量数据集进行投影空间双能量处理。该算法可以使用各种插值方案来实现，并且可以从单片扩展到多片数据采集。在非螺旋投影数据集的注册之后，投影空间处理允许精确的材料量化和虚拟单色图像，其中束固化伪影已被基本上抑制。

19. 发明申请

US20090207967A1 SYSTEM AND METHOD FOR QUANTITATIVE IMAGING OF CHEMICAL COMPOSITION TO DECOMPOSE MULTIPLE MATERIALS 有权
标题翻译：用于定量成像化学成分以分解多种材料的系统和方法
公开(公告)号：US20090207967A1
公开(公告)日：2009-08-20
申请号：US12371433
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： H05G1/60
CPC分类号： A61B6/482 , A61B5/4869 , A61B6/032 , A61B6/4014 , A61B6/4241
摘要： The present invention provides a material decomposition method capable of determining the distribution of density and constituent material concentration throughout an imaged object. The concentration, in the form of a mass fraction, mass percent, weight fraction, or weight percent, is determined from CT images acquired at different energy levels. The ratio of attenuation coefficients associated with one energy level to attenuation coefficients associated with another energy level is determined and used as an index in a lookup table to determine the concentration of a given material throughout the imaged object.
摘要翻译：本发明提供一种能够确定整个成像对象的密度和构成材料浓度分布的材料分解方法。以不同能级获得的CT图像确定以质量分数形式的质量百分比，重量分数或重量百分比的浓度。确定与一个能级相关联的衰减系数与与另一能级相关联的衰减系数的比率，并将其用作查找表中的索引，以确定整个成像对象中给定材料的浓度。

20. 发明授权

US09208585B2 System and method for improved energy series of images using multi-energy CT 有权
标题翻译：使用多能量CT改进能量系列图像的系统和方法
公开(公告)号：US09208585B2
公开(公告)日：2015-12-08
申请号：US13809800
申请日：2011-07-18
申请人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
发明人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
IPC分类号： G06T11/00 , A61B6/03 , A61B6/00 , G01N23/04
CPC分类号： G06T11/003 , A61B6/032 , A61B6/4241 , A61B6/482 , A61B6/50 , A61B6/5205 , G01N23/046 , G01N2223/1016 , G01N2223/419 , G01N2223/423 , G06T5/20
摘要： A method for creating an energy series of images acquired using a multi-energy computed tomography (CT) imaging system having a plurality of energy bins includes acquiring, with the multi-energy CT imaging system, a series of energy data sets, where each energy data set is associated with at least one of the energy bins. The method includes producing a conglomerate image using at least a plurality of the energy data sets and, using the conglomerate image, reconstructing an energy series of images, each image in the energy series of images corresponding to at least one of the energy data sets.
摘要翻译：一种用于创建使用具有多个能量箱的多能量计算机断层摄影（CT）成像系统获取的能量系列图像的方法包括采用多能CT成像系统获取一系列能量数据集，其中每个能量数据集与至少一个能量箱相关联。该方法包括使用至少多个能量数据集生成聚集图像，并且使用该聚集图像重建能量系列的图像，能量系列图像中的每个图像对应于能量数据集中的至少一个。

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