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11. 发明申请

US20050027015A1 Composition comprising cysteamine for improving lactation in dairy animals 审中-公开
标题翻译：包含用于改善乳制品动物哺乳期间的半胱胺的组合物
公开(公告)号：US20050027015A1
公开(公告)日：2005-02-03
申请号：US10489700
申请日：2002-09-18
申请人： Francis Chi , Qin Wen , Tian Lu
发明人： Francis Chi , Qin Wen , Tian Lu
IPC分类号： A23K1/00 , A23K1/14 , A23K1/16 , A23K1/18 , A61K9/30 , A61K31/13 , A61K31/131 , A61K47/40 , A61P5/30 , A61P15/14
CPC分类号： A61K31/13 , A23K20/105 , A23K50/10
摘要： The use of cysteamine, a salt thereof or a composition containing cysteamine or a salt thereof for improving lactation of lactating animals.
摘要翻译：使用半胱胺，其盐或含有半胱胺或其盐的组合物来改善哺乳动物的哺乳期。

12. 发明申请

US20090048154A1 Compositions and Methods for Treating Diabetes 有权
标题翻译：治疗糖尿病的组合物和方法
公开(公告)号：US20090048154A1
公开(公告)日：2009-02-19
申请号：US12259721
申请日：2008-10-28
申请人： Bill Piu CHAN , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
发明人： Bill Piu CHAN , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
IPC分类号： A61K38/28 , A61K31/145 , A61K31/155
CPC分类号： A61K31/155 , A61K31/13 , A61K31/198 , A61K38/28 , A61K45/06 , Y10S514/866 , A61K2300/00
摘要： The subject invention provides compositions and methods for treating diabetes in patients. In a preferred embodiment, the invention provides compositions methods for treating diabetes and/or preventing or alleviating complications associated with diabetes. Specifically exemplified herein is the concurrent administration of a cysteamine compound with at least one additional therapeutic agent to prevent and/or treat diabetes as well as prevent and/or treat complications associated with diabetes. In a preferred embodiment, oral administration of cysteamine hydrochloride with Metformin to a patient diagnosed with diabetes can substantially regulate the patient's glucose metabolism and insulin sensitivity.
摘要翻译：本发明提供了治疗患者糖尿病的组合物和方法。在优选的实施方案中，本发明提供了用于治疗糖尿病和/或预防或减轻与糖尿病相关并发症的组合物方法。本文具体举例说明的是同时施用半胱胺化合物与至少一种另外的治疗剂以预防和/或治疗糖尿病以及预防和/或治疗与糖尿病相关的并发症。在优选的实施方案中，将半胱胺盐酸盐与二甲双胍口服给予诊断患有糖尿病的患者可以基本上调节患者的葡萄糖代谢和胰岛素敏感性。

13. 发明申请

US20060140906A1 Composition comprising cysteamine for improving immunity of animals 审中-公开
标题翻译：包含用于提高动物免疫力的半胱胺的组合物
公开(公告)号：US20060140906A1
公开(公告)日：2006-06-29
申请号：US10546127
申请日：2004-02-17
申请人： Francis Chi , Qin Wen
发明人： Francis Chi , Qin Wen
IPC分类号： A61K38/20 , A61K31/13 , A61K31/724
CPC分类号： A61K31/131 , A23K20/105 , A23K50/10
摘要： There is provided a new use of cysteamine, a salt thereof, or a composition containing cysteamine or a salt thereof, for improving immunity of animals.
摘要翻译：提供半胱胺，其盐或含有半胱胺或其盐的组合物的新用途，用于改善动物的免疫力。

14. 发明申请

US20050148674A1 Materials and methods for improving alcohol metabolism and alleviating the effects of hangovers 有权
标题翻译：改善酒精代谢和减轻宿醉效果的材料和方法
公开(公告)号：US20050148674A1
公开(公告)日：2005-07-07
申请号：US10982160
申请日：2004-11-05
申请人： Wen Tang , Francis Chi
发明人： Wen Tang , Francis Chi
IPC分类号： A61K31/13
CPC分类号： A61K31/145 , A61K31/13 , A61K45/06
摘要： The subject invention provides materials and methods for improving alcohol metabolism in animals. In a preferred embodiment, the invention provides methods for increasing the ability of people to consume alcohol while reducing hangovers or other effects of intoxication. Specifically exemplified herein is the use of a cysteamine compound to reduce the adverse effects of alcohol consumption. For example, the undesirable and unpleasant symptoms association with hangovers can be reduced through consumption, according to the subject invention, of cysteamine hydrochloride.
摘要翻译：本发明提供用于改善动物中的酒精代谢的材料和方法。在优选的实施方案中，本发明提供了增加人们饮用酒精的能力的方法，同时减少宿醉或其他中毒效果。具体举例说明的是使用半胱胺化合物来减少饮酒的不利影响。例如，根据本发明，通过半盐胺盐酸盐的消费可以减少与宿醉的不良和不愉快的症状相关联。

15. 发明申请

US20050143473A1 Methods for treating allergy 审中-公开
标题翻译：治疗过敏的方法
公开(公告)号：US20050143473A1
公开(公告)日：2005-06-30
申请号：US11015362
申请日：2004-12-17
申请人： Gary Wong , Francis Chi
发明人： Gary Wong , Francis Chi
IPC分类号： A61K31/095 , A61K31/13
CPC分类号： A61K31/095 , A61K31/13
摘要： The subject invention provides materials and methods for treating allergy in animals. In a preferred embodiment, the invention provides methods for alleviating an animal's hypersensitive response to allergens, including, without limitation, migraine, asthma, allergic rhinitis, digestive disturbances, coeliac disease, conjunctivitis, urticaria, eczema, drowsiness, hyperactivity (in children), tinnitus, recurrent sinusitis and ear infections. Specifically exemplified herein is the use of a cysteamine compound to reduce the hypersensitive response in animals to allergens. In a preferred embodiment, oral administration of cysteamine hydrochloride to an animal diagnosed with an allergy can substantially reduce the animal's reaction to the allergen.
摘要翻译：本发明提供了用于治疗动物过敏的材料和方法。在优选的实施方案中，本发明提供了减轻动物对变应原的过敏反应的方法，包括但不限于偏头痛，哮喘，过敏性鼻炎，消化系统紊乱，乳糜泻，结膜炎，荨麻疹，湿疹，嗜睡，多动症（儿童）耳鸣，复发性鼻窦炎和耳部感染。本文具体示例是使用半胱胺化合物来减少动物对过敏原的过敏反应。在优选的实施方案中，将半胱胺盐酸盐口服给予诊断为过敏的动物可以显着降低动物对变应原的反应。

16. 发明申请

US20050004075A1 Composition for regulating animal growth, method of manufacture and use thereof 审中-公开
标题翻译：用于调节动物生长的组合物，其制备方法和用途
公开(公告)号：US20050004075A1
公开(公告)日：2005-01-06
申请号：US10885261
申请日：2004-07-06
申请人： Francis Chi , Qin Wen , Tian Lu
发明人： Francis Chi , Qin Wen , Tian Lu
IPC分类号： A23K1/00 , A23K1/16 , A23K1/18 , A61K31/724 , A61K31/13
CPC分类号： A23K50/30 , A23K20/105 , A23K20/163 , A23K40/10 , A23K40/30
摘要： A method of preparing a composition for regulating animal growth comprising the steps of preparing cysteamine or its salt, and mixing the cysteamine or its salt with cyclodextrin or its derivative in a reactor.
摘要翻译：一种制备用于调节动物生长的组合物的方法，包括以下步骤：制备半胱胺或其盐，并将半胱胺或其盐与环糊精或其衍生物在反应器中混合。

17. 发明授权

US07759398B2 Methods for modulating metabolism 有权
标题翻译：调节代谢的方法
公开(公告)号：US07759398B2
公开(公告)日：2010-07-20
申请号：US11118737
申请日：2005-04-29
申请人： Bill Piu Chan , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
发明人： Bill Piu Chan , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
IPC分类号： A61K31/13 , A61K38/00 , A61K31/715
CPC分类号： A61K31/095 , A61K31/13 , A61K31/426 , A61K31/4439 , A61K38/28 , Y10S514/866
摘要： The subject invention provides materials and methods for modulating a variety of biological factors to treat biological conditions associated with the factors. In one embodiment of the invention, a cysteamine compound is administered to a patient to treat hypercholesterolemia and/or complications associated with hypercholesterolemia. In another embodiment, a cysteamine compound is administered to a patient to prevent the onset of diabetes in an at-risk patient and/or treat or prevent the onset of diabetes-associated complications.
摘要翻译：本发明提供用于调节各种生物因子以治疗与这些因素相关的生物学条件的材料和方法。在本发明的一个实施方案中，向患者施用半胱胺化合物以治疗高胆固醇血症和/或与高胆固醇血症相关的并发症。在另一个实施方案中，向患者施用半胱胺化合物以防止在危险患者中发生糖尿病和/或治疗或预防糖尿病相关并发症的发生。

18. 发明申请

US20090209650A1 Materials and Methods for Improving the health of Shrimp 审中-公开
标题翻译：改善虾健康的材料和方法
公开(公告)号：US20090209650A1
公开(公告)日：2009-08-20
申请号：US12372456
申请日：2009-02-17
申请人： Francis Chi
发明人： Francis Chi
IPC分类号： A61K31/145 , A61P37/00
CPC分类号： A61K31/145 , A23K20/105 , A23K50/80
摘要： The subject invention provides methods for improving shellfish health. In specific embodiments, the invention provides methods for accelerating and/or augmenting shrimp growth; improving immunity; and enhancing fertility in shellfish. To do so, the present invention provides materials and methods for administering a cysteamine compound to shrimp.
摘要翻译：本发明提供了改善贝类健康的方法。在具体实施方案中，本发明提供了用于加速和/或增加虾生长的方法; 提高免疫力并提高贝类的生殖力。为此，本发明提供了向虾提供半胱胺化合物的材料和方法。

19. 发明申请

US20090110740A1 Materials and Methods for Modulating Metabolism 有权
标题翻译：调制代谢的材料和方法
公开(公告)号：US20090110740A1
公开(公告)日：2009-04-30
申请号：US12265447
申请日：2008-11-05
申请人： Bill Piu Chan , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
发明人： Bill Piu Chan , Gary Kwan Po Wong , Jinxian Xu , Francis Chi
IPC分类号： A61K9/50 , A61K31/131 , A61K31/351 , A61P9/10 , A61P3/06 , A61K31/403
CPC分类号： A61K31/095 , A61K31/13 , A61K31/426 , A61K31/4439 , A61K38/28 , Y10S514/866
摘要： The subject invention provides materials and methods for modulating a variety of biological factors to treat biological conditions associated with the factors. In one embodiment of the invention, a cysteamine compound is administered to a patient to treat hypercholesterolemia and/or complications associated with hypercholesterolemia. In another embodiment, a cysteamine compound is administered to a patient to prevent the onset of diabetes in an at-risk patient and/or treat or prevent the onset of diabetes-associated complications.
摘要翻译：本发明提供用于调节各种生物因子以治疗与这些因素相关的生物学条件的材料和方法。在本发明的一个实施方案中，向患者施用半胱胺化合物以治疗高胆固醇血症和/或与高胆固醇血症相关的并发症。在另一个实施方案中，向患者施用半胱胺化合物以防止在危险患者中发生糖尿病和/或治疗或预防糖尿病相关并发症的发生。

20. 发明申请

US20070282001A1 Materials And Methods For Improving Shellfish Health, Immunity And Growth 审中-公开
标题翻译：提高贝类健康，免疫力和生长的材料与方法
公开(公告)号：US20070282001A1
公开(公告)日：2007-12-06
申请号：US11630454
申请日：2005-06-28
申请人： Francis Chi
发明人： Francis Chi
IPC分类号： A61K31/145 , A61K31/197
CPC分类号： A61K31/13 , A23K20/105 , A23K50/80 , Y02A40/818
摘要： The subject invention provides methods for improving shellfish health. In specific embodiments, the invention provides methods for accelerating and/or augmenting shellfish growth; improving immunity; and enhancing fertility in shellfish. To do so, the present invention provides materials and methods for administering a cysteamine compound to shellfish.
摘要翻译：本发明提供了改善贝类健康的方法。在具体实施方案中，本发明提供了用于加速和/或增加贝类生长的方法; 提高免疫力并提高贝类的生殖力。为此，本发明提供了向贝类施用半胱胺化合物的材料和方法。

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