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    • 13. 发明授权
    • Method of measuring distance using ultrasonic waves
    • 使用超声波测量距离的方法
    • US5197019A
    • 1993-03-23
    • US554420
    • 1990-07-19
    • Chantal Delon-Martinmarcel ArditiPierre-Andre FarineJean-Jacques MeisterYanik Tardy
    • Chantal Delon-Martinmarcel ArditiPierre-Andre FarineJean-Jacques MeisterYanik Tardy
    • A61B8/08G01B17/02
    • A61B8/0858G01B17/02
    • A method for measuring the distance e separating two faces (3, 4) of an object (1) employs the ultrasonic wave diffused back by said faces and received by a sensor (6). Following digitalization (11), the temporal signal is transformed (12) into a frequency spectrum. The modulus of the frequency spectrum is established (13) then the logarithmic derivative thereof is calculated (15) from whence there results a useful signal including a periodic signal onto which a linear signal is superposed. Following suppression (14, 16) of the linear signal the useful signal is applied (17) to a frequency window in order to eliminate the noise therefrom. The signal thus obtained is inversely transformed (18) to obtain a signal the amplitude of which is a function of the time and the envelope of this latter signal is determined (19). After having determined the temporal spread .DELTA.t separating the time origin from the envelope peak showing the greatest amplitude, the distance e is calculated from the relation e=c.multidot..DELTA.t/2, c representing the propagation velocity of the ultrasonic wave. The method may be employed for the non-invasive measurement of the thickness or diameter of an artery or indeed for the measurement of the thickness of thin layers.
    • 用于测量分离物体(1)的两个面(3,4)的距离e的方法采用由所述面扩散并由传感器(6)接收的超声波。 在数字化(11)之后,时间信号被变换(12)成频谱。 建立频谱的模数(13),然后计算其对数导数(15),从而产生包括重叠线性信号的周期信号的有用信号。 在线性信号的抑制(14,16)之后,将有用信号(17)施加到频率窗口以消除噪声。 如此获得的信号被逆变换(18)以获得其幅度是时间的函数的信号,并且确定后一信号的包络(19)。 在确定了显示最大幅度的包络峰值的时间原点的时间扩展DELTA t之后,根据表示超声波的传播速度的关系e = c×DELTA t / 2计算距离e。 该方法可用于非侵入性测量动脉的厚度或直径,或实际上用于测量薄层的厚度。
    • 14. 发明授权
    • Method and apparatus for establishing the pressure-diameter relationship
of an artery by non-invasive measures
    • 通过非入侵措施建立动态压力关系的方法和装置
    • US5152297A
    • 1992-10-06
    • US489034
    • 1990-03-06
    • Jean-Jacques MeisterYanik Tardy
    • Jean-Jacques MeisterYanik Tardy
    • A61B5/02A61B5/022
    • A61B5/022
    • This method for establishing the pressure-diameter relationship of an artery employs the measurement results from a non-invasive sensor (3) of the artery diameter, for instance of the humeral artery, and from a non-invasive sensor (4) of the blood pressure applied for instance to the end of a finger. The measurement locations being separated by a distance .DELTA.x, the method provides for the correction of the pressure measurements as if such measurements had been effected at the location of the diameter measurements. The method further provides a correction which takes into account the mechanical properties of the artery, defined by the parameters .alpha., .beta., .gamma., . . . and which are calculated, if necessary by successive iterations, until the pressure-diameter curve appears free from all measurement anomalies (hysteresis). The pressure-diameter relationship enables the calculation of the mechanical properties of the artery, in particular by compliance curves and the propagation velocity as a function of the pressure.
    • 用于建立动脉的压力 - 直径关系的方法使用来自例如肱动脉的动脉直径的非侵入式传感器(3)和来自血液的非侵入性传感器(4)的测量结果 例如施加到手指末端的压力。 测量位置被隔开一段距离DELTA x,该方法提供了压力测量的校正,就好像在直径测量的位置已经进行了这样的测量。 该方法进一步提供了校正,其考虑了由参数α,β,γ定义的动脉的机械性质。 。 。 如果需要,通过连续迭代计算,直到压力 - 直径曲线看起来没有所有测量异常(滞后)。 压力 - 直径关系使得能够计算动脉的机械性质,特别是通过顺应性曲线和传播速度作为压力的函数。
    • 15. 发明申请
    • Adjustable resistance valve for a cerebrospinal fluid shunt system
    • 用于脑脊液分流系统的可调阻力阀
    • US20050085763A1
    • 2005-04-21
    • US10686910
    • 2003-10-16
    • Alec GinggenYanik Tardy
    • Alec GinggenYanik Tardy
    • A61M1/00A61M27/00A61M5/00
    • A61M27/006
    • An adjustable resistance valve for a cerebrospinal fluid shunt system includes an actuator for allowing the selection of the resistance to flow of the valve, a device for selecting at least one passage traversing across the valve, and a resistance system. The resistance system includes a set of passages each defining a different resistance to flow. The passages are disposed in a circle facing the selecting device such as to guide the flow of the cerebrospinal fluid traversing the passage of the selecting device through the selected passage of the resistance system. The actuator enables one to change the relative position of the selecting device with respect to the resistance system by a rotational movement to select the desired resistance of the valve.
    • 用于脑脊液分流系统的可调节阻力阀包括用于允许选择阀的流动阻力的致动器,用于选择穿过阀的至少一个通道的装置和阻力系统。 电阻系统包括一组通道,每个通道限定不同的阻力。 通道设置在面向选择装置的圆圈中,以引导通过选择装置的通道的脑脊液的流动通过电阻系统的选定通道。 致动器使得能够通过旋转运动来改变选择装置相对于电阻系统的相对位置,以选择阀的期望电阻。
    • 16. 发明授权
    • Method for determining the arterial blood pressure in a non-invasive
manner
    • 用于确定非侵入式手术器官腔血压的方法
    • US5099852A
    • 1992-03-31
    • US489038
    • 1990-03-06
    • Jean J. MeisterYanik Tardy
    • Jean J. MeisterYanik Tardy
    • A61B5/022A61B5/021A61B5/0285A61B8/04
    • A61B8/04A61B5/021A61B5/02125A61B5/0285
    • This method for establishing blood pressure in an artery employs the measurement results from two non-invasive sensors (5, 6) of artery diameter at two closely spaced locations (3, 4) separated by a distance .DELTA.x. The method provides for measuring the time spread .DELTA.t(7) between each pair of diameter measurements and establishing the propagation velocity of the pressure wave (9). Next, this value is compared with an expression (11) of the form c(D)= c(D, .alpha., .beta., .gamma., . . . ) which takes into account the physical behavior of the artery. This comparison permits one, following adjustment (12) based on a mathematical procedure for minimizing spreads, to calculate the parameters .alpha., .beta., .gamma., . . . of the relation given hereinabove. By replacing the parameters .alpha., .beta., .gamma., . . . by their values in a relation (10) D(p)= D(p, .alpha., .beta., .gamma., . . . ) and in employing the measurement results from a diameter sensor, one may deduce the blood pressure value p(t) at each instant of the cardiac cycle. The blood pressure value together with the corresponding value of the artery diameter permit tracing a pressure-diameter curve (14) by means of which the mechanical properties of the artery may be measured.
    • 用于在动脉中建立血压的这种方法使用来自两个间隔距离DELTA x的两个紧密间隔的位置(3,4)的动脉直径的两个非侵入性传感器(5,6)的测量结果。 该方法用于测量每对直径测量之间的时间延度Δt(7),并建立压力波的传播速度(9)。 接下来,将该值与考虑到动脉的物理行为的形式c(D)= c(D,α,β,γ,...)的表达式(11)进行比较。 该比较允许一个,基于用于最小化传播的数学过程进行调整(12),以计算参数α+62,γ'。 。 。 的上述关系。 通过替换参数α,β,γ。 。 。 通过其关系式(10)D(p)= D(p,α,+ 62,γ,...)中的值,并且在使用来自直径传感器的测量结果时,可以推导出血压值p )在心动周期的每一瞬间。 血压值与动脉直径的相应值一起,可追踪压力 - 直径曲线(14),借此可以测量动脉的机械性质。