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11. 发明授权

US06461368B2 Vascular clamps and surgical retractors with directional filaments for tissue engagement 有权
标题翻译：血管夹和手术牵开器具有用于组织接合的定向细丝
公开(公告)号：US06461368B2
公开(公告)日：2002-10-08
申请号：US09810866
申请日：2001-03-16
申请人： Thomas J. Fogarty , George D. Hermann , Joshua S. Whittemore , Thomas A. Howell
发明人： Thomas J. Fogarty , George D. Hermann , Joshua S. Whittemore , Thomas A. Howell
IPC分类号： A61B1704
CPC分类号： A61B17/02 , A61B17/122 , A61B2017/0243 , A61B2017/2825 , A61B2017/2837 , A61B2017/320012
摘要： Surgical clamps, tissue retractors and surgical stabilizers are disclosed having gripping surfaces from which extend resilient filaments. The distal ends of some of the resilient filaments abut against engaged vessels, tissues or organs to restrict movement of the vessels, tissue or organs relative to the gripping surfaces. In the preferred embodiment, the resilient filaments are arranged in rows and oriented at particular angles relative to the gripping surfaces. Methods of applying resilient filaments to pads for attachment to a surgical clamp, tissue retractor or surgical stabilizer are also disclosed.
摘要翻译：公开了手术夹具，组织牵缩器和手术稳定器，其具有抓持表面，弹性细丝从该表面延伸。一些弹性细丝的远端抵靠接合的血管，组织或器官，以限制血管，组织或器官相对于抓握表面的移动。在优选实施例中，弹性细丝被排成一列并相对于抓握表面以特定角度定向。还公开了将弹性丝应用于用于附接到手术夹具，组织牵缩器或手术稳定器的垫的方法。

12. 发明授权

US5514151A Valvulotome with a laterally offset curved cutting edge 失效
标题翻译：瓣膜切开，侧向偏移弯曲切削刃
公开(公告)号：US5514151A
公开(公告)日：1996-05-07
申请号：US301324
申请日：1994-09-06
申请人： Thomas J. Fogarty , Thomas A. Howell
发明人： Thomas J. Fogarty , Thomas A. Howell
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/32075 , A61B17/320725 , A61B2017/22097
摘要： A valvulotome that cuts a vein valve leaflet from apex to edge by applying a tensile force to the leaflet. The valvulotome has a shaft, on the distal end of which is a laterally-offset extension, to the distal end of which is attached the distal end of a blade with a curved cutting edge. The blade is substantially parallel to the shaft. The cutting edge faces the extension, which shields the cutting edge. Opposite the cutting edge, the blade has a blunt back that has a substantially straight part, and a part, towards its proximal end, that curves towards the extension. The blade may be pivotally attached to the extension with an actuator that opens or closes the blade. A method of using the valvulotome to carry out a valvotomy in a vein includes piercing the valve leaflet with the valvulotome close to the apex of the leaflet, and applying a tensile force to the leaflet with the valvulotome to cut the leaflet from apex to edge.
摘要翻译：通过向小叶施加张力，从顶端到边缘切割静脉瓣叶瓣的瓣膜切开术。瓣膜切开器具有轴，其远端是横向偏移的延伸部，其远端附接有具有弯曲切割边缘的刀片的远端。刀片基本上平行于轴。切割刃面向延伸部分，其屏蔽切割边缘。与切割刃相对，刀片具有钝的后部，其具有基本上直的部分，并且朝向其近端的朝向延伸部弯曲的部分。叶片可以用打开或关闭叶片的致动器枢转地附接到延伸部。使用瓣膜切开术在静脉中进行瓣膜切开术的方法包括用接近瓣膜顶点的瓣膜切开术刺穿瓣膜小叶，并用瓣膜切开机构对小叶施加张力以从顶端到边缘切割小叶。

13. 发明授权

US06752154B2 Device for accurately marking tissue 有权
标题翻译：用于准确标记组织的装置
公开(公告)号：US06752154B2
公开(公告)日：2004-06-22
申请号：US09935477
申请日：2001-08-22
申请人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
发明人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B17/221 , A61B17/320016 , A61B17/320068 , A61B17/3211 , A61B17/34 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3468 , A61B17/3476 , A61B18/14 , A61B18/1477 , A61B18/149 , A61B2017/008 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00929 , A61B2018/1425 , A61B2090/3908
摘要： This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device. Polar and tangential deployment configurations as well as a locator element that may be cold-formed by a die in the distal portion of the deployment tube into a permanent arcuate shape are also disclosed.
摘要翻译：本发明是一种改进的组织定位装置，用于固定地可移除地标记包含可疑区域的组织的体积用于切除。本发明还包括用于部署定位装置及其切除以及标记的组织体积的方法。至少一个定位元件被部署到组织中并且呈现预定的曲线形状以限定沿着路径包含可疑组织区域的组织边界。定位元件路径优选地包围组织体积的最远部分而不穿透该体积。可以部署多个定位器元件以进一步沿着限定不穿透该体积的组织体积边界的附加路径限定组织体积。公开了本发明的其它定位线实施例，其中组织体积可以被装置的一部分穿透。还公开了极性和切向部署构造以及可以由展开管的远侧部分中的模具冷成形为永久弓形形状的定位元件。

14. 发明授权

US06564806B1 Device for accurately marking tissue 有权
公开(公告)号：US06564806B1
公开(公告)日：2003-05-20
申请号：US09507361
申请日：2000-02-18
申请人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann
发明人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B17/320068 , A61B17/3211 , A61B17/34 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3468 , A61B17/3476 , A61B18/14 , A61B18/1477 , A61B18/149 , A61B2017/008 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00929 , A61B2018/1425 , A61B2090/3908
摘要： This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision without penetrating that volume. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Polar and tangential deployment configurations as well as a locator element that may be cold-formed by a die in the distal portion of the deployment tube into a permanent arcuate shape is also disclosed.

15. 发明授权

US06206896B1 Surgical clamp pad with interdigitating teeth 有权
标题翻译：外科手术钳与交叉齿
公开(公告)号：US06206896B1
公开(公告)日：2001-03-27
申请号：US09361750
申请日：1999-07-27
申请人： Thomas A. Howell , Douglas S. Sutton , Thomas J. Fogarty
发明人： Thomas A. Howell , Douglas S. Sutton , Thomas J. Fogarty
IPC分类号： A61B1708
CPC分类号： A61B17/1227 , A61B17/122 , A61B2017/2825 , A61B2017/2837
摘要： Opposable surgical clamp members having opposable resilient pads with wedge-shaped and cylindrical protrusions extending from the surfaces of the pads and the use of such members for occluding vessels and other tubular body structures are described. The protrusions are arranged such that when the members are moved toward one another, the protrusions of one pad interdigitate with the protrusions of the other pad. Upon engagement with a vessel, portions of the vessel are forced into the interdigital spaces providing for improved gripping of the vessel. The protrusions also resist lateral or transverse movement of a clamped vessel relative to the pads. The existence of holes under the pad surface alters the relative resiliency of the pad, allowing for an overall pad resiliency that minimizes trauma to a clamped vessel while allowing the local resiliency of the protrusions themselves to be of a hardness to avoid excessive deflection and retain the desired shape and gripping ability.
摘要翻译：描述了具有可从垫的表面延伸的楔形和圆柱形突起的相对的弹性垫以及用于封闭容器和其它管状结构的这种构件的使用的相对的手术夹具。突起被布置成使得当构件彼此移动时，一个垫的突起与另一个垫的突起相互交错。在与容器接合时，容器的部分被迫进入叉指间空间，从而改善对容器的抓握。这些突起还抵抗夹持的容器相对于衬垫的横向或横向移动。衬垫表面下方的孔的存在改变了垫的相对弹性，允许整体衬垫弹性使得对夹紧的容器的创伤最小化，同时允许突起本身的局部弹性具有硬度以避免过度偏转并保持期望的形状和抓握能力。

16. 发明授权

US5618287A Methods of surgically implanting a defibrillator electrode within a patient 失效
标题翻译：在患者体内手术植入除颤器电极的方法
公开(公告)号：US5618287A
公开(公告)日：1997-04-08
申请号：US406125
申请日：1995-03-17
申请人： Thomas J. Fogarty , Thomas A. Howell
发明人： Thomas J. Fogarty , Thomas A. Howell
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/0587
摘要： Improved implantable defibrillator electrodes and methods of implanting such electrodes are disclosed. One embodiment of the defibrillator electrodes includes a flexible conductive mesh and non-conductive mesh. Another embodiment of the defibrillator electrodes includes a flexible conductive mesh, a non-conductive mesh and an insulator therebetween. A third embodiment of the defibrillator electrode compensates for the shape of a human heart.Methods for implanting the defibrillator electrodes include rolling an electrode and inserting the rolled electrode into a subxiphoid opening while thorascopically observing the insertion and manipulation of the defibrillator electrode.
摘要翻译：公开了改进的可植入除颤电极和植入这种电极的方法。除颤器电极的一个实施例包括柔性导电网和非导电网。除颤器电极的另一实施例包括柔性导电网，非导电网和它们之间的绝缘体。除颤器电极的第三实施例补偿人心脏的形状。用于植入除颤器电极的方法包括滚动电极并将卷绕的电极插入副尖端开口，同时胸部观察除颤器电极的插入和操纵。

17. 发明授权

US5584842A Valvulotome and method of using 失效
标题翻译：瓣膜切开及使用方法
公开(公告)号：US5584842A
公开(公告)日：1996-12-17
申请号：US253929
申请日：1994-06-30
申请人： Thomas J. Fogarty , Thomas A. Howell , Jan R. Wicherski , Stephen A. Sosnowski
发明人： Thomas J. Fogarty , Thomas A. Howell , Jan R. Wicherski , Stephen A. Sosnowski
IPC分类号： A61B17/22 , A61B17/32 , A61B17/34 , A61D1/02
CPC分类号： A61B17/32075 , A61B17/320725 , A61B2017/22097
摘要： A valvulotome for disrupting vein valves in in-situ procedures, and for distrupting the vein valves in vein segments to be used in CABG procedures. The valvulotome includes an elongate blade mounting member and a thin, scythe-shaped cutting blade. The cutting blade is mounted relative to the blade mounting member such that the plane defined by the blade lies on the axis defined by the blade mounting member. The cutting blade has a fixed end, a free end, a cutting edge and a blunt back edge. The fixed end is fixedly attached to a distal portion of the blade mounting member. The sharpened edge faces towards the blade mounting member, which protects the vein from the sharpened edge. The sharpened edge arcs outwards and proximally from the distal portion of the blade mounting member, and terminates in a proximal portion, spaced from the blade mounting member. The blunt back edge is opposite the sharpened edge, facing the vein. The free end is opposite the fixed end and connects the blunt back edge to the proximal portion of the sharpened edge. The free end including a blunt proximal-facing portion that forms a continuation of the blunt back edge.
摘要翻译：用于在现场手术中破坏静脉瓣的瓣膜切开术，以及用于扰乱CABG手术中使用的静脉节段中的静脉瓣。瓣膜切开机包括细长的刀片安装构件和薄的Scythe形切割刀片。切割刀片相对于刀片安装部件安装，使得由刀片限定的平面位于由刀片安装部件限定的轴线上。切割刀片具有固定端，自由端，切削刃和钝的后缘。固定端固定地附接到刀片安装构件的远端部分。锋利的边缘面向刀片安装构件，其保护静脉免受锋利的边缘的影响。锋利的边缘从叶片安装构件的远侧部分向外和近侧弧形，并且终止于与叶片安装构件间隔开的近端部分。钝的后缘与锋利的边缘相对，面向静脉。自由端与固定端相对，并将钝后缘连接到锐化边缘的近端部分。自由端包括形成钝后缘的延续的钝的近端部分。

18. 发明授权

US06953464B2 Anastomosis occlusion device 有权
标题翻译：吻合闭塞装置
公开(公告)号：US06953464B2
公开(公告)日：2005-10-11
申请号：US10058577
申请日：2002-01-28
申请人： Terrence Buelna , Adam Gold , Thomas J. Fogarty , Thomas A. Howell
发明人： Terrence Buelna , Adam Gold , Thomas J. Fogarty , Thomas A. Howell
IPC分类号： A61B17/00 , A61B17/04 , A61B17/11 , A61B17/12 , A61B17/122 , A61F2/01 , H04M1/02
CPC分类号： A61B17/122 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B17/11 , A61B17/12022 , A61B17/12036 , A61B17/1204 , A61B17/12045 , A61B17/12109 , A61B17/12131 , A61B17/12172 , A61B2017/00252 , A61B2017/00641 , A61B2017/1135 , A61F2/01
摘要： An anastomosis occlusion device having a low-profile shaft assembly configured for insertion into the lumen of a vessel and a distal perfusion system adapted to be connected to the shaft assembly. The device includes an expandable region at the shaft assembly distal end with a sealing membrane that spans the expandable region, and a corresponding clamping member moveable toward the expandable region. Once inserted into the vessel lumen the expandable region is deployed from a first low-profile position into a second expanded position, and positioned at the target site of the anastomosis. Movement of the distal end of the clamping member, which remains located outside the vessel, against the expanded region creates a seal at the target site allowing a blood-free, graft site.
摘要翻译：一种吻合闭塞装置，其具有构造成用于插入血管内腔的低轮廓轴组件和适于连接到所述轴组件的远端灌注系统。该装置包括位于轴组件远端处的可膨胀区域，其具有跨越可膨胀区域的密封膜，以及可朝向可扩张区域移动的相应的夹紧构件。一旦插入血管腔，可扩张区域从第一低调位置展开到第二扩张位置，并且位于吻合的目标位置。保持在容器外部的夹持构件的远端抵靠扩张区域的运动在目标位置产生密封，从而允许无血液的移植部位。

19. 发明授权

US06405733B1 Device for accurately marking tissue 有权
标题翻译：用于准确标记组织的装置
公开(公告)号：US06405733B1
公开(公告)日：2002-06-18
申请号：US09613686
申请日：2000-07-11
申请人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , M. Elizabeth Bush
发明人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , M. Elizabeth Bush
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B17/320068 , A61B17/3211 , A61B17/34 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3468 , A61B17/3476 , A61B18/14 , A61B18/1477 , A61B18/149 , A61B2017/008 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00929 , A61B2018/1425 , A61B2090/3908
摘要： This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision without penetrating that volume. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Polar and tangential deployment configurations as well as a locator element that may be cold-formed by a die in the distal portion of the deployment tube into a permanent arcuate shape is also disclosed.
摘要翻译：本发明是一种改进的组织定位装置，用于固定地并可移除地标记含有可疑区域的组织的体积，用于切除而不穿透该体积。本发明还包括用于部署定位装置及其切除以及标记的组织体积的方法。至少一个定位元件被部署到组织中并且呈现预定的曲线形状以限定沿着路径包含可疑组织区域的组织边界。定位元件路径优选地包围组织体积的最远部分而不穿透该体积。可以部署多个定位器元件以进一步沿着限定不穿透该体积的组织体积边界的附加路径限定组织体积。还公开了极性和切向部署构造以及可以由展开管的远侧部分中的模具冷成形为永久弓形形状的定位元件。

20. 发明授权

US06007552A Vascular clamps and surgical retractors with directional filaments for tissue engagement 失效
标题翻译：血管夹和手术牵开器具有用于组织接合的定向细丝
公开(公告)号：US06007552A
公开(公告)日：1999-12-28
申请号：US993076
申请日：1997-12-18
申请人： Thomas J. Fogarty , George D. Hermann , Joshua S. Whittemore , Thomas A. Howell
发明人： Thomas J. Fogarty , George D. Hermann , Joshua S. Whittemore , Thomas A. Howell
IPC分类号： A61B17/02 , A61B17/12 , A61B17/122 , A61B17/28 , A61B17/32 , A61B17/00
CPC分类号： A61B17/02 , A61B17/122 , A61B2017/0243 , A61B2017/2825 , A61B2017/2837 , A61B2017/320012
摘要： A surgical clamp or tissue retractor is disclosed having gripping surfaces from which extend resilient filaments. The distal ends of some of the resilient filaments abut against the engaged vessel or tissue to restrict movement of the vessel or tissue relative to the gripping surfaces. In the preferred embodiment, the resilient filaments are arranged in rows and oriented at particular angles relative to the gripping surfaces.
摘要翻译：公开了一种手术夹具或组织牵缩器，其具有夹持表面，弹性细丝从该抓握表面延伸。一些弹性细丝的远端抵靠接合的血管或组织以限制血管或组织相对于抓握表面的运动。在优选实施例中，弹性细丝被排成一列并相对于抓握表面以特定角度定向。

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