专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20090200719A1 Fluid-filled cylindrical vibration-damping device 有权
标题翻译：流体填充圆柱形减振装置
公开(公告)号：US20090200719A1
公开(公告)日：2009-08-13
申请号：US12320925
申请日：2009-02-09
申请人： Kazuhiko Kato , Takashi Kume
发明人： Kazuhiko Kato , Takashi Kume
IPC分类号： F16F13/00
CPC分类号： F16F13/1427
摘要： A fluid filled cylindrical vibration damping device having a main rubber elastic body elastically connecting an inner shaft member and an intermediate cylindrical member, wherein base wall portions of either of a pair of pocket portions are constituted by the main rubber elastic body to actively rise opposing positive/negative pressure fluctuations in a pair of fluid chambers at times of vibration input across the inner shaft member and the outer cylindrical member; a low-frequency orifice passage and a high-frequency orifice passage are provided; and the high-frequency orifice passage is provided in an aperture section thereof leading to at least one of the pair of fluid chambers with a moveable film adapted to limit fluid flow through the high-frequency orifice passage on the basis of displacement and/or deformation thereof.
摘要翻译：一种流体填充的圆柱形减振装置，其具有弹性地连接内轴构件和中间圆筒构件的主橡胶弹性体，其中一对凹部中的任一个的基壁部分由主橡胶弹性体构成，以主动地增加相对的正在穿过内轴构件和外圆柱形构件的振动输入时一对流体室中的负压波动; 提供低频孔通道和高频孔通道; 并且高频孔通道设置在其开口部分中，其通过可移动膜导向至少一个流体室，该可移动膜适于基于位移和/或变形来限制流过高频孔通道的流体其中。

12. 发明授权

US06943271B2 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same 有权
标题翻译：制备含氟聚合性苯乙烯单体的方法及其中使用的中间体
公开(公告)号：US06943271B2
公开(公告)日：2005-09-13
申请号：US10600510
申请日：2003-06-23
申请人： Shinichi Sumida , Takashi Kume , Sunao Koga , Haruhiko Komoriya
发明人： Shinichi Sumida , Takashi Kume , Sunao Koga , Haruhiko Komoriya
IPC分类号： C07C29/58 , C07B61/00 , C07C29/00 , C07C29/17 , C07C33/30 , C07F7/08 , C07C41/08 , C07F7/02
CPC分类号： C07C29/00 , C07C29/17 , C07F7/081 , C07C33/483
摘要： A fluorine-containing styrene monomer of the formula (2) is produced by a first, second or third process. The first process includes (a) reacting a compound of the formula (1) with a compound of the formula (3), in the presence of a metal catalyst; (b) reacting the product of the step (a) with a base; and (c) reacting the product of the step (b) with hydrogen, in the presence of a metal catalyst and a phosphine or amine, thereby producing the target styrene monomer. The second process includes reacting a compound of the formula (1) with a compound of the formula (12), in the presence of a metal catalyst, thereby producing the target styrene monomer. The third process includes reacting a compound of the formula (13) with a compound of the formula (14) or (15), in the presence of a base, thereby producing the target styrene monomer.
摘要翻译：通过第一，第二或第三工艺制备式（2）的含氟苯乙烯单体。第一种方法包括（a）在金属催化剂存在下使式（1）化合物与式（3）化合物反应; （b）使步骤（a）的产物与碱反应; 和（c）在金属催化剂和膦或胺的存在下，使步骤（b）的产物与氢反应，由此制备目标苯乙烯单体。第二种方法包括在金属催化剂的存在下使式（1）的化合物与式（12）的化合物反应，由此制备目标苯乙烯单体。第三种方法包括在碱的存在下使式（13）的化合物与式（14）或（15）的化合物反应，由此制备目标苯乙烯单体。

13. 发明授权

US06362372B1 Process for producing trifluoromethylbenzylamines 有权
公开(公告)号：US06362372B1
公开(公告)日：2002-03-26
申请号：US09833210
申请日：2001-04-12
申请人： Satoru Narizuka , Takashi Kume
发明人： Satoru Narizuka , Takashi Kume
IPC分类号： C07C20900
摘要： The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1), where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4. The process includes hydrogenating a trifluoromethylbenzonitrile by hydrogen in an organic solvent in the presence of ammonia and a catalyst containing a platinum group element. This trifluoromethylbenzonitrile is represented by the following general formula (2), where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine at an extremely high yield.

14. 发明授权

US08304580B2 Method for producing tris(perfluoroalkanesulfonyl)methide acid salt 有权
标题翻译：三（全氟烷基磺酰基）甲基化物酸盐的制备方法
公开(公告)号：US08304580B2
公开(公告)日：2012-11-06
申请号：US12520178
申请日：2007-12-18
申请人： Tsutomu Nanmyo , Shintaro Sasaki , Takashi Kume
发明人： Tsutomu Nanmyo , Shintaro Sasaki , Takashi Kume
IPC分类号： C07C315/00
CPC分类号： C07C315/00 , C07C315/04 , C07F3/02 , C07C317/04
摘要： There is provided a method for producing a tris(perfluoroalkanesulfonyl)methide acid salt represented by formula [1], including the steps of (a) reacting a methylmagnesium halide represented by formula [2] with a perfluoroalkanesulfonyl fluoride represented by formula [3], thereby obtaining a reaction mixture; and (b) directly reacting the obtained reaction mixture with at least one selected from the group consisting of alkali metal halides, quaternary ammonium salts, and quaternary phosphonium salts. By this method, it is possible to easily produce the target methide acid salt with high yield.
摘要翻译：提供了一种由式[1]表示的三（全氟烷基磺酰基）甲基化物酸盐的制备方法，其包括以下步骤：（a）使式[2]表示的甲基卤化镁与式[3]表示的全氟烷基磺酰氟反应，从而得到反应混合物; 和（b）使所得反应混合物与选自碱金属卤化物，季铵盐和季鏻盐中的至少一种直接反应。通过该方法，可以容易地以高产率制备目标甲基化酸盐。

15. 发明授权

US08128075B2 Fluid-filled cylindrical vibration-damping device 有权
标题翻译：流体填充圆柱形减振装置
公开(公告)号：US08128075B2
公开(公告)日：2012-03-06
申请号：US12320925
申请日：2009-02-09
申请人： Kazuhiko Kato , Takashi Kume
发明人： Kazuhiko Kato , Takashi Kume
IPC分类号： F16F5/00
CPC分类号： F16F13/1427
摘要： A fluid filled cylindrical vibration damping device having a main rubber elastic body elastically connecting an inner shaft member and an intermediate cylindrical member, wherein base wall portions of either of a pair of pocket portions are constituted by the main rubber elastic body to actively rise opposing positive/negative pressure fluctuations in a pair of fluid chambers at times of vibration input across the inner shaft member and the outer cylindrical member; a low-frequency orifice passage and a high-frequency orifice passage are provided; and the high-frequency orifice passage is provided in an aperture section thereof leading to at least one of the pair of fluid chambers with a moveable film adapted to limit fluid flow through the high-frequency orifice passage on the basis of displacement and/or deformation thereof.
摘要翻译：一种流体填充的圆柱形减振装置，其具有弹性地连接内轴构件和中间圆筒构件的主橡胶弹性体，其中一对凹部中的任一个的基壁部分由主橡胶弹性体构成，以主动地增加相对的正在穿过内轴构件和外圆柱形构件的振动输入时一对流体室中的负压波动; 提供低频孔通道和高频孔通道; 并且高频孔通道设置在其开口部分中，其通过可移动膜导向至少一个流体室，该可移动膜适于基于位移和/或变形来限制流过高频孔通道的流体其中。

16. 发明申请

US20050159896A1 Apparatus and method for analyzing data 审中-公开
标题翻译：用于分析数据的装置和方法
公开(公告)号：US20050159896A1
公开(公告)日：2005-07-21
申请号：US10509886
申请日：2003-03-31
申请人： Toshio Ishikawa , Takashi Kume
发明人： Toshio Ishikawa , Takashi Kume
IPC分类号： G06F19/20 , G06F19/24 , G06F19/00
CPC分类号： G16B25/00 , G16B40/00
摘要： In a data analysis system for determining a correlation model between biological conditions and expression levels of a plurality of genes and/or quantities of intracellular substances, A data set is constructed by using the biological conditions or changes of the biological conditions probabilistically generated with time as object variables, and the expression levels of the plural genes and/or the quantities of intracellular substances as explanatory variables. The explanatory variables contained in the data are selected, and cross validation is calculated for a correlation model containing the selected explanatory variables and object variables to assess the results. Selection of the explanatory variables, calculation of cross validation and discriminative assessment of the result is repeated until no further improvement of the cross validation is observed to determine a partial least square model. This permits an effective processing method to provide multivariable gene information.
摘要翻译：在用于确定生物学条件和多个基因和/或数量的细胞内物质的表达水平之间的相关模型的数据分析系统中，通过使用生物条件或随时间概率地产生的生物学条件的变化来构建A数据集对象变量，以及多个基因的表达水平和/或细胞内物质的量作为解释变量。选择数据中包含的解释变量，并对包含所选解释变量和对象变量的相关模型计算交叉验证，以评估结果。重复说明变量的选择，交叉验证的计算和结果的区别性评估，直到不能观察到交叉验证的进一步改进以确定偏最小二乘模型。这允许有效的处理方法提供多变量基因信息。

17. 发明授权

US06326517B1 Method of producing benzamides 失效
标题翻译：生产苯甲酰胺的方法
公开(公告)号：US06326517B1
公开(公告)日：2001-12-04
申请号：US09458079
申请日：1999-12-10
申请人： Takashi Kume , Michio Ishida , Satoru Narizuka , Yuzuru Morino , Makoto Koide
发明人： Takashi Kume , Michio Ishida , Satoru Narizuka , Yuzuru Morino , Makoto Koide
IPC分类号： C07C23100
CPC分类号： C07C231/10 , C07C233/65
摘要： A method of producing benzamides represented by the following general formula (1): where R is trifluoromethyl group, trifluoromethyloxy group, halogen (fluorine, chlorine, bromine or iodine), nitro group, acetyl group, cyano group, alkyl group having 1 to 4 carbon atoms, alkoxy group having 1 to 4 carbon atoms, or a alkoxycarbonyl group having 2 to 5 carbon atoms; and n is 0 or an integer ranging from 1 to 3. The method comprises the step of allowing an aromatic compound represented by the following general formula (2) to react with carbon monoxide and ammonia in the presence of a metal of the group VIII of the periodic table and phosphine: where X is halogen (fluorine, chlorine, bromine or iodine), trifluoromethanesulfonate group, alkylsulfonate group having 1 to 4 carbon atoms, or substituted or unsubstituted arylsulfonate group; R is trifluoromethyl group, trifluoromethyloxy group, halogen (fluorine, chlorine, bromine or iodine), nitro group, acetyl group, cyano group, alkyl group having 1 to 4 carbon atoms, alkoxy group having 1 to 4 carbon atoms, or alkoxycarbonyl group having 2 to 5 carbon atoms; and n is 0 or an integer ranging from 1 to 3.
摘要翻译：一种生产由以下通式（1）表示的苯甲酰胺的方法：其中R是三氟甲基，三氟甲氧基，卤素（氟，氯，溴或碘），硝基，乙酰基，氰基，具有1-4个碳原子数1〜4的烷氧基或碳原子数2〜5的烷氧基羰基。并且n为0或1至3的整数。该方法包括以下通式（2）表示的芳族化合物与一氧化碳和氨在VIII族金属存在下反应的步骤：周期表和膦：其中X是卤素（氟，氯，溴或碘），三氟甲磺酸酯基，具有1至4个碳原子的烷基磺酸酯基或取代或未取代的芳基磺酸酯基; R为三氟甲基，三氟甲氧基，卤素（氟，氯，溴或碘），硝基，乙酰基，氰基，碳原子数1〜4的烷基，碳原子数1〜4的烷氧基， 2至5个碳原子; n为0或1〜3的整数。

18. 发明授权

US06175041B1 Process for producing trifluoromethylbenzylamines 失效
标题翻译：制备三氟甲基苄胺的方法
公开(公告)号：US06175041B1
公开(公告)日：2001-01-16
申请号：US09521009
申请日：2000-03-07
申请人： Seiji Takasaki , Takahiro Koizumi , Takashi Kume , Michio Ishida , Satoru Narizuka , Eri Tsukada
发明人： Seiji Takasaki , Takahiro Koizumi , Takashi Kume , Michio Ishida , Satoru Narizuka , Eri Tsukada
IPC分类号： C07C20900
CPC分类号： C07C209/48 , C07C211/29
摘要： The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1). This process includes hydrogenating a trifliuoromethylbenzonitrile represented by the following general formula (2) by hydrogen in an organic solvent in the presence of ammonia, using a Raney catalyst, where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4, where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine easily and inexpensively at an extremely high yield.
摘要翻译：本发明涉及一种由以下通式（1）表示的三氟甲基苄胺的制备方法。该方法包括使用阮内催化剂，在氨的存在下，在有机溶剂中，用氢气氢化由以下通式（2）表示的三氟甲基苄腈，其中每个R独立地表示选自氟，氯，溴的卤素和碘，碳原子数为1-4的烷基，碳原子数为1-4的烷氧基，氨基，羟基或三氟甲基，n为0-4的整数其中R和n如上定义。通过该方法，可以以极高的收率容易且廉价地得到三氟甲基苄基胺。

19. 发明授权

US06878663B2 Method for producing palladium complex compound 失效
标题翻译：钯配合物的制造方法
公开(公告)号：US06878663B2
公开(公告)日：2005-04-12
申请号：US10116057
申请日：2002-04-05
申请人： Takashi Kume , Satoru Narizuka , Makoto Koide , Koichi Mikami , Manabu Hatano , Masahiro Terada
发明人： Takashi Kume , Satoru Narizuka , Makoto Koide , Koichi Mikami , Manabu Hatano , Masahiro Terada
IPC分类号： C07F15/00 , C07F17/02
CPC分类号： C07F15/006 , C07F15/0066
摘要： An aromatic compound represented by the general formula Ar1X is reacted with a palladium compound and a phosphine derivative, in the presence of a first basic substance, thereby producing a palladium-complex compound represented by the general formula Ar1—PdL2X. This palladium-complex compound is reacted with a benzoic acid represented by the general formula Ar2—COOH, in the presence of a second basic substance, thereby producing another palladium-complex compound represented by the following general formula. The above palladium-complex compounds are useful as catalysts and can be produced easily by the above reactions. In the above general formulas, Ar1 is an aryl group; and X is a halogen that is fluorine, chlorine, bromine or iodine, trifluoromethanesulfonate group, an alkylsulfonate group having a carbon atom number of 1-4, or a substituted or unsubstituted arylsulfonate group; each L is independently a phosphine ligand; and Ar2 is an aryl group.
摘要翻译：在通式Ar 1 X表示的芳香族化合物与钯化合物和膦衍生物在第一碱性物质的存在下反应，由此制备由通式Ar 1〜 PdL2X。在第二碱性物质的存在下，使该钯络合物与通式为Ar 2 -COOH表示的苯甲酸反应，由此生成由以下通式表示的另一种钯络合物。复合化合物可用作催化剂，并且可以通过上述反应容易地制备。在上述通式中，Ar 1是芳基; X是氟，氯，溴或碘的卤素，三氟甲磺酸酯基，碳原子数为1-4的烷基磺酸酯基或取代或未取代的芳基磺酸酯基; 每个L独立地是膦配体; Ar 2为芳基。

20. 发明授权

US06706905B1 Method for producing palladium complex compound 失效
标题翻译：钯配合物的制造方法
公开(公告)号：US06706905B1
公开(公告)日：2004-03-16
申请号：US09458080
申请日：1999-12-10
申请人： Takashi Kume , Satoru Narizuka , Makoto Koide , Koichi Mikami , Manabu Hatano , Masahiro Terada , Michio Ishida , Yuzuru Morino
发明人： Takashi Kume , Satoru Narizuka , Makoto Koide , Koichi Mikami , Manabu Hatano , Masahiro Terada , Michio Ishida , Yuzuru Morino
IPC分类号： C07F1702
CPC分类号： C07F15/006 , C07F15/0066
摘要： An aromatic compound represented by the general formula Ar1X is reacted with a palladium compound and a phosphine derivative, in the presence of a first basic substance, thereby producing a palladium-complex compound represented by the general formula Ar1—PdL2X. This palladium-complex compound is reacted with a benzoic acid represented by the general formula Ar2—COOH, in the presence of a second basic substance, thereby producing another palladium-complex compound represented by the following general formula. The above palladium-complex compounds are useful as catalysts and can be produced easily by the above reactions. In the above general formulas, Ar1 is an aryl group; and X is a halogen that is fluorine, chlorine, bromine or iodine, trifluoromethanesulfonate group, an alkylsulfonate group having a carbon atom number of 1-4, or a substituted or unsubstituted arylsulfonate group; each L is independently a phosphine ligand; and Ar2 is an aryl group.
摘要翻译：在通式Ar 1 X表示的芳香族化合物与钯化合物和膦衍生物在第一碱性物质的存在下反应，由此制备由通式Ar 1〜 PdL2X。在第二碱性物质的存在下，使该钯络合物与通式为Ar 2 -COOH表示的苯甲酸反应，由此生成由以下通式表示的另一种钯络合物。复合化合物可用作催化剂，并且可以通过上述反应容易地制备。在上述通式中，Ar 1是芳基; X是氟，氯，溴或碘的卤素，三氟甲磺酸酯基，碳原子数为1-4的烷基磺酸酯基或取代或未取代的芳基磺酸酯基; 每个L独立地是膦配体; Ar 2为芳基。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式