专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20110086798A1 ERYTHROPOIETIN COMPOSITIONS 失效
标题翻译：胡萝卜素组合物
公开(公告)号：US20110086798A1
公开(公告)日：2011-04-14
申请号：US12779171
申请日：2010-05-13
申请人： Natarajan Sethuraman , Juergen Nett , Robert Davidson
发明人： Natarajan Sethuraman , Juergen Nett , Robert Davidson
IPC分类号： A61K38/18 , C12N15/09 , A61P7/00
CPC分类号： C07K14/505 , C12P21/005
摘要： Methods and materials are provided for the production of compositions of erythropoietin protein, wherein said compositions comprise a pre-selected N-linked glycosylation pattern as the predominant N-glycoform.
摘要翻译：提供了用于生产促红细胞生成素蛋白质组合物的方法和材料，其中所述组合物包含预先选择的N-连接的糖基化模式作为主要的N-糖基型。

12. 发明授权

US08815544B2 Production of galactosylated glycoproteins in lower eukaryotes 有权
标题翻译：低等真核生物中半乳糖基化糖蛋白的产生
公开(公告)号：US08815544B2
公开(公告)日：2014-08-26
申请号：US12840529
申请日：2010-07-21
申请人： Robert Davidson , Tillman Gerngross , Stefan Wildt , Byung-Kwon Choi , Juergen Hermann Nett , Piotr Bobrowicz , Stephen Robin Hamilton
发明人： Robert Davidson , Tillman Gerngross , Stefan Wildt , Byung-Kwon Choi , Juergen Hermann Nett , Piotr Bobrowicz , Stephen Robin Hamilton
IPC分类号： C12P21/02 , C12P19/04 , A61K38/00
CPC分类号： C12P21/005 , C12N9/1051 , C12N15/1082 , C12N15/79 , Y10S435/911
摘要： The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal β-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.
摘要翻译：本发明提供了一种产生人类糖蛋白的新型低级真核宿主细胞，其特征在于具有末端半乳糖残基并且基本上缺乏岩藻糖和唾液酸残基。本发明还提供了一种催化将半乳糖残基从UDP-半乳糖转移到可用作治疗性糖蛋白的重组低等真核宿主细胞中的受体底物上的方法。

13. 发明授权

US07795002B2 Production of galactosylated glycoproteins in lower eukaryotes 有权
标题翻译：低等真核生物中半乳糖基化糖蛋白的产生
公开(公告)号：US07795002B2
公开(公告)日：2010-09-14
申请号：US11108088
申请日：2005-04-15
申请人： Robert Davidson , Tillman Ulf Gerngross , Stefan Wildt , Byung-Kwon Choi , Juergen Hermann Nett , Piotr Bobrowicz , Stephen Robin Hamilton
发明人： Robert Davidson , Tillman Ulf Gerngross , Stefan Wildt , Byung-Kwon Choi , Juergen Hermann Nett , Piotr Bobrowicz , Stephen Robin Hamilton
IPC分类号： C12N15/04 , A61K38/00
CPC分类号： C12P21/005 , C12N9/1051 , C12N15/1082 , C12N15/79 , Y10S435/911
摘要： The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal β-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.
摘要翻译：本发明提供了一种产生人类糖蛋白的新型低级真核宿主细胞，其特征在于具有末端半乳糖残基并且基本上缺乏岩藻糖和唾液酸残基。本发明还提供了一种催化将半乳糖残基从UDP-半乳糖转移到可用作治疗性糖蛋白的重组低等真核宿主细胞中的受体底物上的方法。

14. 发明申请

US20160376002A1 Aircraft with Rotating Outer Shell 审中-公开
标题翻译：带旋转外壳的飞机
公开(公告)号：US20160376002A1
公开(公告)日：2016-12-29
申请号：US14626209
申请日：2015-02-19
申请人： Robert Davidson
发明人： Robert Davidson
IPC分类号： B64C39/00 , B64C29/00 , B64C15/02 , B64C1/16 , B64C17/06
CPC分类号： B64C39/001
摘要： An aircraft having a main body defining a passenger compartment therein, an upper shell portion above the main body and a lower shell portion below the main body, further includes a motor assembly operatively connected between the upper shell portion, the lower shell portion and the main body so as to be arranged to drive rotation of the upper and lower shell portions relative to the main body in opposing directions relative to one another. An engine assembly is supported on the main body in communication with a central thrust opening in the lower shell portion so as to be arranged to provide upward thrust to the main body.
摘要翻译：一种具有在其中限定乘客舱的主体的飞行器，主体上方的上壳体部分和主体下方的下壳体部分，还包括可操作地连接在上壳体部分，下壳体部分和主体部分之间的马达组件主体以相对于彼此的相反方向相对于主体驱动上壳体部分和下壳体部分的旋转。发动机组件支撑在主体上，与下壳体部分中的中心推力开口连通，以便向主体提供向上的推力。

15. 发明申请

US20150337274A1 PMT2-, OCH1-, PMT5- MUTANT CELLS 审中-公开
标题翻译： PMT2-，OCH1，PMT5-突变体细胞
公开(公告)号：US20150337274A1
公开(公告)日：2015-11-26
申请号：US14652964
申请日：2013-12-13
申请人： Ming-Tang CHEN , Byung-Kwon CHOI , Robert DAVIDSON , MERCK SHARP & DOHME CORP.
发明人： Ming-Tang Chen , Byung-Kwon Choi , Robert Davidson
IPC分类号： C12N9/12 , C12P21/00
CPC分类号： C12N9/1241 , C07K16/00 , C07K16/2887 , C07K16/32 , C07K2317/14 , C07K2317/41 , C12N9/1051 , C12P21/005
摘要： The presented invention relates to the gene knockouts of the Pichia pastoris PMT2 gene in the och1-glycoengineered strain backgrounds to obtain recombinant proteins reduced amounts of O-linked glycosylation. Triple mutant, pmt2, pmt5, och1 strains are also part of the present invention. Method for making such strains and for producing heterologous polypeptides in such strains are also included in the present invention.
摘要翻译：本发明涉及Och1-糖工程菌株背景中巴斯德毕赤酵母PMT2基因的基因敲除，以获得重组蛋白质减少量的O-连接糖基化。三重突变体，pmt2，pmt5，och1菌株也是本发明的一部分。在这些菌株中制备这种菌株和产生异源多肽的方法也包括在本发明中。

16. 发明申请

US20140121191A1 Oral Energy Supplement and Related Methods 审中-公开
标题翻译：口腔能量补充和相关方法
公开(公告)号：US20140121191A1
公开(公告)日：2014-05-01
申请号：US13850292
申请日：2013-03-25
申请人： Robert Davidson , Eric Allen , Edward Maliski , Jose Bernado
发明人： Robert Davidson , Eric Allen , Edward Maliski , Jose Bernado
IPC分类号： A61K31/555 , A61K31/045 , A61K45/06 , A61K31/44 , A61K31/4985 , A61K31/455 , A61K31/522
CPC分类号： A61K31/555 , A61K9/127 , A61K31/045 , A61K31/44 , A61K31/455 , A61K31/4985 , A61K31/522 , A61K45/06 , A61K2300/00
摘要： The present invention relates to oral dosage formulations consisting of at least one active ingredient contained in a plurality of hydrophobic carriers dispersed in an aqueous medium comprising a hydrocolloid. The active ingredients include various energy supplements, such as caffeine and vitamins. The formulations may further include emulsifiers, permeation enhancers, and vasodilators. The invention further relates to methods of making the oral dosage formulations.
摘要翻译：本发明涉及由分散在包含水胶体的水性介质中的多个疏水载体中所含的至少一种活性成分组成的口服剂型。活性成分包括各种能量补充剂，如咖啡因和维生素。制剂还可以包括乳化剂，渗透促进剂和血管扩张剂。本发明还涉及制备口服剂型的方法。

17. 发明申请

US20130311267A1 METHODS FOR AND APPARATUS FOR PROVIDING USER SPECIFIC GUIDANCE 审中-公开
标题翻译：用于提供用户特定指导的方法和装置
公开(公告)号：US20130311267A1
公开(公告)日：2013-11-21
申请号：US13607761
申请日：2012-09-09
申请人： Robert Davidson
发明人： Robert Davidson
IPC分类号： G06Q30/06
CPC分类号： G06Q30/0631
摘要： The present invention provides methods and apparatus for associating Emotional Motivators with a Product. The Emotional Motivators associated with the Products are correlated with Emotional Motivators associated with a Purchaser. Advice regarding a Purchase may be provided based upon the correlated Emotional Motivators.
摘要翻译：本发明提供了将情绪动机与产品相关联的方法和装置。与产品相关的情绪动机与与买方相关的情绪动机相关。有关购买的建议可能会根据相关的情绪动机来提供。

18. 发明申请

US20130309363A1 Oral Colloidal Electrolyte Solution and Related Methods 审中-公开
标题翻译：口腔胶体电解质溶液及相关方法
公开(公告)号：US20130309363A1
公开(公告)日：2013-11-21
申请号：US13850289
申请日：2013-03-25
申请人： Robert Davidson , Eric Allen , Edward Maliski , Jose Bernado
发明人： Robert Davidson , Eric Allen , Edward Maliski , Jose Bernado
IPC分类号： A23L1/29
CPC分类号： A23L33/16 , A23L33/40
摘要： The present invention relates to oral dosage formulations consisting of at least one active ingredient contained in a plurality of hydrophobic carriers dispersed in an aqueous medium comprising a hydrocolloid. The active ingredients include various forms of electrolytes. The formulations may further include emulsifiers, permeation enhancers, and vasodilators. The invention further relates to methods of making the oral dosage formulations.
摘要翻译：本发明涉及由分散在包含水胶体的水性介质中的多个疏水载体中所含的至少一种活性成分组成的口服剂型。活性成分包括各种形式的电解质。制剂还可以包括乳化剂，渗透促进剂和血管扩张剂。本发明还涉及制备口服剂型的方法。

19. 发明申请

US20130246174A1 METHODS FOR AND APPARATUS FOR ASSOCIATING EMOTIONAL MOTIVATORS WITH PRODUCTS 审中-公开
标题翻译：用于与产品相关的EMOTIVE MOTIVATOR的方法和装置
公开(公告)号：US20130246174A1
公开(公告)日：2013-09-19
申请号：US13607757
申请日：2012-09-09
申请人： Robert Davidson , Fanny Chung Davidson , Belinda Womack , Dmitry Korobkov
发明人： Robert Davidson , Fanny Chung Davidson , Belinda Womack , Dmitry Korobkov
IPC分类号： G06Q30/06
CPC分类号： G06Q30/0631
摘要： The present invention provides methods and apparatus for associating Emotional Motivators with a Product. The Emotional Motivators associated with the Products are correlated with Emotional Motivators associated with a Purchaser. Advice regarding a Purchase may be provided based upon the correlated Emotional Motivators.
摘要翻译：本发明提供了将情绪动机与产品相关联的方法和装置。与产品相关的情绪动机与与买方相关的情绪动机相关。有关购买的建议可能会根据相关的情绪动机来提供。

20. 发明申请

US20080045620A1 Piperazino Based Photoinitiators 有权
标题翻译：基于哌嗪基的光引发剂
公开(公告)号：US20080045620A1
公开(公告)日：2008-02-21
申请号：US11718952
申请日：2005-11-09
申请人： Shaun Herlihy , Brian Rowatt , Robert Davidson
发明人： Shaun Herlihy , Brian Rowatt , Robert Davidson
IPC分类号： C07D413/02 , C07D241/02 , C07D413/14 , C08F2/48
CPC分类号： C07D295/135 , C07D295/112 , C07D295/15
摘要： Compounds of formula (I): [where: the substituents R1 are individually selected from C1-C10 alkyl groups and optionally substituted benzyl groups; the substituents R2 are individually selected from alkyl groups or, together with the nitrogen atom to which they are attached, represent a nitrogen-containing heterocyclic group; Z is selected from C6-C10 arylene groups groups of formula —(CHR3)n—, where R3 is hydrogen, hydroxy or a C1-C4 alkyl group, and n is 0 to 6; Y is carbonyl or a residue of a mono- or poly-hydroxy compound; and x is 1 to 6; and esters thereof] are useful as multi-functional photoinitiators for use in coating compositions to be cured by radiant energy.
摘要翻译：式（I）化合物：其中：取代基R 1分别选自C 1 -C 10烷基和任选取代的苄基团体取代基R 2分别选自烷基或与它们所连接的氮原子一起代表含氮杂环基; Z选自式-C（CHR 3）n N - 的C 6 -C 10亚芳基，其中R 3为氢，羟基或C 1 -C 4烷基，n为0至6; Y是羰基或单羟基或多羟基化合物的残基; x为1〜6; 及其酯]可用作多功能光引发剂，用于通过辐射能固化的涂料组合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式