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    • 16. 发明授权
    • Stable, homogeneous, extract free or nearly free form secondary reaction products
    • 稳定,均匀,无释放或几乎自由形成二次反应产物
    • US06340479B1
    • 2002-01-22
    • US09722618
    • 2000-11-28
    • Matthias H. KreuterRudolf Steiner
    • Matthias H. KreuterRudolf Steiner
    • A61K3578
    • A61K36/185A61K36/00A61K36/38A61K36/48A61K36/66A61K36/8962A61K2300/00
    • A stable, homogeneous extract of plants or plant parts prepared by a process comprising: (a) mixing plants or plant parts charged in a fresh and/or dried state with at least one solvent and at least one agent and extracting the plants or plant parts with the solvent and agent, and thereafter filtering insoluble compounds to obtain a filtrate; or (b) mixing and extracting plants or parts thereof charged in a fresh and/or dried state with at least one solvent, thereafter filtering insoluble compounds therefrom, and thereafter mixing with at least one agent to obtain a filtrate; wherein the filtrate is substantially free of secondary reaction products and contains a native compound mixture. The agent: (i) increases the solubility of at least one extracted compound contained in the filtrate; (ii) increases the viscosity of the filtrate in the presence of the solvent(s); (iii) decreases the steam pressure of volatile extracted compounds contained in the filtrate; (iv) prevents or reduces the chemical and/or enzymatic reactions between one or more extracted compounds contained in the filtrate; (v) prevents or reduces the sedimentation and/or flotation of extracted compounds contained in the filtrate when the filtrate is in liquid or semisolid form or is dissolved and/or suspended and/or emulsified in at least one solvent; and (vi) increases the stability and/or homogeneity of at least one extracted compounds contained in the filtrate.
    • 通过包括以下步骤制备的植物或植物部分的稳定的均质提取物:(a)将以新鲜和/或干燥状态装入的植物或植物部分与至少一种溶剂和至少一种试剂混合并提取植物或植物部分 用溶剂和试剂,然后过滤不溶性化合物,得到滤液; 或者(b)用至少一种溶剂混合提取新鲜和/或干燥状态的植物或其部分,然后从其中过滤不溶性化合物,然后与至少一种试剂混合以获得滤液; 其中所述滤液基本上不含次级反应产物并含有天然化合物混合物。 该试剂:(i)提高滤液中所含的至少一种萃取化合物的溶解度; (ii)在溶剂存在下增加滤液的粘度; (iii)降低滤液中含有的挥发性萃取化合物的蒸汽压力; (iv)防止或减少滤液中含有的一种或多种提取的化合物之间的化学和/或酶反应; (v)当滤液为液体或半固体形式或溶解和/或悬浮和/或在至少一种溶剂中乳化时,防止或减少滤液中所含萃取化合物的沉淀和/或浮选; 和(vi)增加滤液中所含的至少一种提取的化合物的稳定性和/或均匀性。