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11. 发明授权

US06939639B2 Fuel cell separator 失效
标题翻译：燃料电池分离器
公开(公告)号：US06939639B2
公开(公告)日：2005-09-06
申请号：US10243745
申请日：2002-09-16
申请人： Toshiyuki Inagaki , Tsuyoshi Takahashi , Tsutomu Ochi , Katsuhiro Kajio , Kouetsu Hibino , Yasuyuki Asai , Yixin Zeng , Toshiyuki Suzuki , Yuichi Yagami , Mikio Wada , Haruhisa Niimi
发明人： Toshiyuki Inagaki , Tsuyoshi Takahashi , Tsutomu Ochi , Katsuhiro Kajio , Kouetsu Hibino , Yasuyuki Asai , Yixin Zeng , Toshiyuki Suzuki , Yuichi Yagami , Mikio Wada , Haruhisa Niimi
IPC分类号： H01M2/18 , H01M8/02 , H01M8/04
CPC分类号： H01M8/0206 , H01M8/0258 , H01M8/026 , H01M8/0265 , H01M8/0267
摘要： A fuel cell separator is pressed so that one side thereof defines a gas flow channel and that the other side thereof defines a coolant flow channel. A width dG and a cross-sectional area SG of the gas flow channel and a width dW and a cross-sectional area Sw of the coolant flow channel satisfy a relationship: dG≧dW or a relationship: SG≧SW.
摘要翻译：燃料电池分离器被压制，使得其一侧限定气体流动通道，并且其另一侧限定冷却剂流动通道。气体流动通道的宽度d N G和横截面面积S N G和横截面积S 冷却剂流动通道的满足以下关系：d = d 或关系：S＆lt; > = S 。

12. 发明授权

US06828155B1 Method for evaluating lipid a analog-containing injections 失效
标题翻译：用于评估含类似物的注射液的脂质的方法
公开(公告)号：US06828155B1
公开(公告)日：2004-12-07
申请号：US09786060
申请日：2001-03-01
申请人： Kazuhiro Kaneko , Tomohiro Watanabe , Yasuyuki Asai , Yoshihisa Sano , Kiyomi Kikuchi , Ikuo Kushida , Kazuhide Ashizawa
发明人： Kazuhiro Kaneko , Tomohiro Watanabe , Yasuyuki Asai , Yoshihisa Sano , Kiyomi Kikuchi , Ikuo Kushida , Kazuhide Ashizawa
IPC分类号： G01N3300
CPC分类号： A61K9/0019 , A61K31/739 , G01N21/19 , G01N21/6445 , G01N33/92
摘要： The present invention provides an evaluation method and preparation process of injection containing a lipid A analog. Specifically, it provides, in an injection preparation containing a lipid A analog or a pharmacologically acceptable salt thereof, forecasting and evaluating methods of the pharmacokinetics of the lipid A analog, and quality evaluating method and preparation process of the injection, which each comprises measuring membrane fluidity and/or circular dichroism.
摘要翻译：本发明提供含有脂质A类似物的注射液的评价方法和制备方法。具体而言，在含有脂质A类似物或其药理学上可接受的盐的注射制剂中，提供了脂质A类似物的药代动力学的预测和评估方法以及注射的质量评估方法和制备方法，每种方法包括测量膜流动性和/或圆二色性。

13. 发明授权

US06331002B1 Sheet feeding apparatus 失效
标题翻译：送纸装置
公开(公告)号：US06331002B1
公开(公告)日：2001-12-18
申请号：US09627451
申请日：2000-07-27
申请人： Hiroshi Yoshino , Jun Katayanagi , Haruyuki Yanagi , Shinya Sonoda , Yasuyuki Asai
发明人： Hiroshi Yoshino , Jun Katayanagi , Haruyuki Yanagi , Shinya Sonoda , Yasuyuki Asai
IPC分类号： B65H306
CPC分类号： B65H3/5223 , B65H3/0661 , B65H2404/1112
摘要： The present invention provides a sheet feeding apparatus for separating and feeding sheets one by one, which has sheet stacking device for supporting sheets, a sheet feeding roller, provided at its periphery with a cylindrical surface and a cut-out portion, for feeding out the sheet stacked on the sheet stacking device by means of the cylindrical surface by rotating, separation device, capable of abutting against the sheet feeding roller, for separating the sheets one by one between the cylindrical surface of the sheet feeding roller and the separation device, spacing device for spacing apart the sheet feeding roller and the separation device when the cut-out portion of the sheet feeding roller is opposed to the separation device, biasing device for biasing the separation device to urge it against the sheet feeding roller or the spacing device, and conveying load reducing device for reducing a conveying load acting on the sheet being fed, by making an abutment force for pinching the sheet between the spacing device and the separation device smaller than an abutment force for pinching the sheet between the cylindrical surface and the separation device.
摘要翻译：本发明提供一种用于一张一张地分离和供给片材的片材进给装置，该片材进给装置具有用于支撑片材的片材堆叠装置，在其周边设置有圆柱形表面和切口部分的片材进给辊，通过旋转分离装置，通过旋转的分离装置将纸张堆叠装置堆叠在片材堆叠装置上，该装置能够抵靠供纸辊，用于在片材进给辊的圆柱形表面和分离装置之间逐个分离片材，间隔当片材进给辊的切口部分与分离装置相对时间隔开供纸辊和分离装置的装置，用于偏压分离装置以将其推压到供纸辊或间隔装置的偏置装置，以及输送减载装置，用于通过形成用于夹紧sh的邻接力来减小作用在被供给的片材上的输送负荷间隔装置和分离装置之间的距离小于用于将片材夹在圆柱形表面和分离装置之间的邻接力。

14. 发明授权

US09856210B2 Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis 有权
公开(公告)号：US09856210B2
公开(公告)日：2018-01-02
申请号：US13820420
申请日：2011-09-02
申请人： Haruhisa Inoue , Shiho Kitaoka , Kayoko Tsukita , Ryosuke Takahashi , Gaku Murakami , Norio Nakatsuji , Motonari Uesugi , Yasuyuki Asai , Ayako Asai , Yuji Amagai , Kazuhiro Aiba
发明人： Haruhisa Inoue , Shiho Kitaoka , Kayoko Tsukita , Ryosuke Takahashi , Gaku Murakami , Norio Nakatsuji , Motonari Uesugi , Yasuyuki Asai , Yuji Amagai , Kazuhiro Aiba
IPC分类号： A61K31/17 , A61K31/44 , A61K45/06 , C07C275/30
CPC分类号： C07C275/30 , A61K31/17 , A61K31/44 , A61K45/06 , A61K2300/00
摘要： The present invention provides a prophylactic or therapeutic agent for amyotrophic lateral sclerosis, containing a 1,3-diphenylurea derivative or multikinase inhibitor.

15. 发明授权

US09527828B2 Method for expanding hematopoietic stem cells using heterocyclic compound 有权
标题翻译：使用杂环化合物扩增造血干细胞的方法
公开(公告)号：US09527828B2
公开(公告)日：2016-12-27
申请号：US12746666
申请日：2008-12-06
申请人： Taito Nishino , Norihisa Ishiwata , Katsuaki Miyaji , Shunsuke Iwamoto , Yasuyuki Asai , Makiko Yui
发明人： Taito Nishino , Norihisa Ishiwata , Katsuaki Miyaji , Shunsuke Iwamoto , Yasuyuki Asai , Makiko Yui
IPC分类号： C12N5/00 , C07D333/38 , C07D409/14 , C07D413/14 , C07D417/14 , C12N5/0789 , A61K35/00
CPC分类号： C07D333/38 , A61K35/00 , C07D409/14 , C07D413/14 , C07D417/14 , C12N5/0647 , C12N2501/999
摘要： An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various hematopoietic disorders is provided.A method for expanding hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises culturing hematopoietic stem cells and/or hematopoietic progenitor cells ex vivo in the presence of a compound represented by the formula (I) (wherein X, Y, X, Ar1, R1, R2, R3, R4, R5, R6 and R7 are defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：提供了用于造血干细胞和/或造血祖细胞的扩增剂，其用于提高用于治疗各种造血障碍的用于基因治疗的造血干细胞的基因转移效率。一种用于扩增造血干细胞和/或造血祖细胞的方法，其包括在式（I）表示的化合物（其中X，Y，X，Ar）存在下离体培养造血干细胞和/或造血祖细胞 1，R 1，R 2，R 3，R 4，R 5，R 6和R 7在说明书中定义），化合物的互变异构体或药学上可接受的盐或其溶剂合物。

16. 发明授权

US09212348B2 Method for producing hematopoietic stem cells using pyrazole compounds 有权
标题翻译：使用吡唑化合物制造造血干细胞的方法
公开(公告)号：US09212348B2
公开(公告)日：2015-12-15
申请号：US13990959
申请日：2011-12-01
申请人： Taito Nishino , Makiko Yui , Yasuyuki Asai , Ayako Asai
发明人： Taito Nishino , Makiko Yui , Yasuyuki Asai
IPC分类号： C12N15/00 , C12N5/0789 , C07D231/22 , A61K35/28
CPC分类号： C12N5/0647 , A61K35/28 , C07D231/22 , C12N2501/125 , C12N2501/145 , C12N2501/26 , C12N2501/999
摘要： An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided.A method of producing hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises expanding hematopoietic stem cells by culturing hematopoietic stem cells ex vivo in the presence of a compound represented by the formula following (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof (wherein R1 to R8 are as defined in the description).
摘要翻译：提供了用作造血干细胞和/或造血祖细胞的扩增剂，其用作各种造血疾病的治疗，并且可用于提高基因转移到造血干细胞中用于基因治疗的效率。一种产生造血干细胞和/或造血祖细胞的方法，其包括通过在下列通式（I）表示的化合物存在下体外培养造血干细胞来扩大造血干细胞，其中所述化合物的互变异构体或药学上可接受的盐化合物或其溶剂化物（其中R1至R8如说明书中所定义）。

17. 发明授权

US09099693B2 Fuel cell and fuel cell separator 有权
标题翻译：燃料电池和燃料电池分离器
公开(公告)号：US09099693B2
公开(公告)日：2015-08-04
申请号：US11886292
申请日：2006-03-23
申请人： Hiroya Nakaji , Tsutomu Ochi , Chisato Kato , Tsunemasa Nishida , Manabu Takahashi , Yasuyuki Asai
发明人： Hiroya Nakaji , Tsutomu Ochi , Chisato Kato , Tsunemasa Nishida , Manabu Takahashi , Yasuyuki Asai
IPC分类号： H01M8/04 , H01M8/02 , H01M8/10
CPC分类号： H01M8/2483 , H01M8/0228 , H01M8/0258 , H01M8/0267 , H01M8/0271 , H01M8/0276 , H01M2008/1095 , Y02E60/50
摘要： In a fuel cell having a separator in which main cooling water channels are formed, a separator for another unit cell stacked on the cooling water channel formation surface side of the separator, and a second sealing member interposed between the separators and to seal a cooling medium flowing in the main cooling water channels, an outer peripheral rib for regulating the flow of cooling water to the second sealing member side is provided inside relative to the second sealing member in the separator surface direction in order to improve the efficiency of cooling with the cooling medium.
摘要翻译：在具有形成有主冷却水通道的隔板的燃料电池中，叠层在隔板的冷却水通道形成面侧的另一单元电池用隔板，以及插入在隔板之间并密封冷却介质的第二密封构件在主冷却水通道中流动，在隔板表面方向上相对于第二密封构件设置有用于调节冷却水流向第二密封构件侧的外周肋，以提高冷却效率中。

18. 发明授权

US08636278B2 Feeding device and image forming apparatus having the same 有权
标题翻译：送料装置及其成像装置
公开(公告)号：US08636278B2
公开(公告)日：2014-01-28
申请号：US12946218
申请日：2010-11-15
申请人： Yuki Emoto , Yasuyuki Asai
发明人： Yuki Emoto , Yasuyuki Asai
IPC分类号： B65H3/52
CPC分类号： B65H3/0684 , B65H3/56 , B65H2402/543 , B65H2405/1136 , B65H2511/212 , B65H2515/30 , B65H2220/02 , B65H2220/08 , B65H2220/11 , B65H2220/01
摘要： The feeding device includes a storage unit, a feeding roller which rotates while contacting the uppermost sheet stored in the storage unit to move the uppermost sheet forward, a separation plate disposed forward in the movement direction of the uppermost sheet and provided with an inclined surface inclined with respect to the movement direction, and a separation auxiliary member is disposed along the inclined surface of the separation plate and operated by a force received when the uppermost sheet comes in contact. The separation auxiliary member includes a rotation shaft parallel with the inclined surface, and a first resistance part rotating about the rotation shaft as the center from an initial position projecting from the inclined surface to an embedded position embedded in the inclined surface as a friction coefficient of the first resistance part is higher than that of the inclined surface and the received force is increased.
摘要翻译：所述进给装置包括存储单元，所述进给辊在与所述存储单元中存储的最上面的纸张接触的同时旋转，以将最上面的纸张向前移动;分隔板，其在最上面的纸张的移动方向上向前设置，并且分离辅助构件沿着分离板的倾斜表面设置并且通过当最上面的片材接触时接收的力而操作。分离辅助构件包括与倾斜表面平行的旋转轴，以及第一电阻部分，其以从倾斜表面突出到初始位置的旋转轴为中心旋转到嵌入在倾斜表面中的嵌入位置，摩擦系数为第一电阻部分高于倾斜表面，并且接收力增加。

19. 发明授权

US07641186B2 Sheet feeding/conveying method and sheet feeding/conveying apparatus 失效
标题翻译：送纸/送纸方式和送纸/送纸装置
公开(公告)号：US07641186B2
公开(公告)日：2010-01-05
申请号：US11165166
申请日：2005-06-24
申请人： Yasuyuki Asai , Noboru Shimoyama
发明人： Yasuyuki Asai , Noboru Shimoyama
IPC分类号： B65H3/06
CPC分类号： B65H9/006 , B41J13/103 , B65H3/06 , B65H3/5261 , B65H2301/331 , B65H2301/512125 , B65H2404/7231
摘要： A sheet material feeding apparatus has a rotatable pressure plate for stacking sheet materials, a pickup roller for feeding the sheet material stacked on the pressure plate, a feed roller for feeding the sheet materials fed by the pickup roller and a separation roller contactable with the feed roller. A registration roller corrects oblique feeding of the sheet material by being abutted against the separated sheet material by the feeding roller and the separation roller, and after the registration roller rotates in synchronism with the pickup roller and the feed roller to start feeding the sheet material, pressure of the pressure plate against the pickup roller is released, and thereafter the feed roller and the separation roller are spaced apart from one another.
摘要翻译：片材供给装置具有用于堆叠片材的可旋转压板，用于供给堆叠在压板上的片材的拾取辊，用于馈送由拾取辊馈送的片材的进给辊和可与进给器接触的分离辊滚筒。定位辊通过由进给辊和分离辊抵靠分离的片材来校正片材的倾斜进给，并且在定位辊与拾取辊和进给辊同步旋转以开始进给片材之后，压力板抵靠拾取辊的压力被释放，之后进给辊和分离辊彼此间隔开。

20. 发明申请

US20080265481A1 RECORDING APPARATUS 有权
标题翻译：录音设备
公开(公告)号：US20080265481A1
公开(公告)日：2008-10-30
申请号：US12107699
申请日：2008-04-22
申请人： Haruo Uchida , Kenji Kawazoe , Nozomu Nishiberi , Koichiro Kawaguchi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
发明人： Haruo Uchida , Kenji Kawazoe , Nozomu Nishiberi , Koichiro Kawaguchi , Yoshiaki Watanabe , Yasuyuki Asai , Mitsuru Kondo
IPC分类号： B41F13/64
CPC分类号： B65H3/0607 , B65H3/44 , B65H9/106 , B65H2301/23 , B65H2801/06
摘要： A recording apparatus includes moving rollers and a feeding roller. The moving rollers move a set first sheet in a direction intersecting a conveying direction. The feeding roller conveys sheets at a sheet stacking portion. After the first sheet is shifted to a parallel position by the moving roller, a second sheet at a setting position and the first sheet at the parallel position are conveyed by the feeding roller.
摘要翻译：记录装置包括移动辊和进给辊。移动辊在与输送方向相交的方向上移动设定的第一片。送纸辊在片材堆叠部分输送纸张。在通过移动辊将第一片材移动到平行位置之后，在设置位置处的第二片材和平行位置处的第一片材通过进给辊传送。

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