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11. 发明授权

US07913561B2 Ultrasonic wave vibrating apparatus 有权
标题翻译：超声波振动仪
公开(公告)号：US07913561B2
公开(公告)日：2011-03-29
申请号：US12025962
申请日：2008-02-05
申请人： Norihiro Yamada , Masashi Yamada , Yukichi Hanayama , Nobuyuki Suda
发明人： Norihiro Yamada , Masashi Yamada , Yukichi Hanayama , Nobuyuki Suda
IPC分类号： G01N29/34 , H04R1/02 , B08B3/00
CPC分类号： B08B3/12 , B06B3/00
摘要： An ultrasonic wave vibrating apparatus includes a passive element converting electric energy to ultrasonic vibration, electrodes, a horn body arranged in a forward side of the element and amplifying the vibration, a backing arranged in the base side of the element and backing the element, and a horn connecting portion having one end connected to the body and the other end connected to the backing to connect the body and the backing to each other with the element sandwiched between the body and the backing. At least one of the body, the connecting portion and the backing is formed of metallic glass. The body and the connecting portion can be formed of the metallic glass integrally with each other. A cover covering the element may be included, and the cover, the body and the connecting portion can be formed of the metallic glass integrally with each other.
摘要翻译：超声波振动装置包括将电能转换为超声波振动的无源元件，电极，布置在元件前侧的喇叭体并放大振动，布置在元件的基底侧并支撑元件的背衬，以及喇叭连接部分，其一端连接到主体，另一端连接到背衬，以将身体和背衬彼此连接，并将夹持在身体和背衬之间的元件连接。主体，连接部分和背衬中的至少一个由金属玻璃形成。主体和连接部分可以由金属玻璃彼此一体地形成。可以包括覆盖元件的盖，并且盖，主体和连接部可以由金属玻璃彼此一体地形成。

12. 发明申请

US20100144815A1 AMINO ACID COMPOSITION 审中-公开
标题翻译：氨基酸组合物
公开(公告)号：US20100144815A1
公开(公告)日：2010-06-10
申请号：US12449663
申请日：2008-02-25
申请人： Hiroshi Tsuchita , Masato Saito , Kazuo Shin , Yukihiko Kubota , Masashi Yamada , Keisuke Seki
发明人： Hiroshi Tsuchita , Masato Saito , Kazuo Shin , Yukihiko Kubota , Masashi Yamada , Keisuke Seki
IPC分类号： A61K31/4172 , A61P3/00
CPC分类号： A61K31/198 , A23L2/52 , A23L33/175 , A23L33/40 , A23V2002/00 , A61K31/401 , A61K31/4172 , A23V2200/332 , A23V2200/33 , A23V2250/061 , A23V2250/0648 , A23V2250/0642 , A23V2250/0618 , A23V2250/064 , A23V2250/0622 , A23V2250/0604 , A23V2250/0654 , A23V2250/0616 , A23V2250/0632 , A23V2250/0626 , A23V2250/0628 , A23V2250/0652 , A23V2250/0638 , A23V2250/063 , A23V2250/065 , A23V2250/0624 , A23V2250/0606
摘要： An amino acid composition is provided that can promote fat burning, improve endurance, and reduce fatigue during, for example, marathons, and that can lessen obesity and increase stress resistance.The amino acid composition comprises 3.0 to 10.0 mass parts of aspartic acid, 2.5 to 9.0 mass parts of threonine, 2.0 to 9.5 mass parts of serine, 12.0 to 40.0 mass parts of glutamic acid, 7.0 to 20.0 mass parts of proline, 0.5 to 4.5 mass parts of glycine, 1.0 to 4.5 mass parts of alanine, 3.0 to 12.0 mass parts of valine, 0.1 to 0.8 mass part of cystine, 1.5 to 5.0 mass parts of methionine, 2.0 to 8.0 mass parts of isoleucine, 5.0 to 15.0 mass parts of leucine, 3.0 to 10.0 mass parts of tyrosine, 3.0 to 10.0 mass parts of phenylalanine, 4.0 to 15.0 mass parts of lysine, 0.8 to 4.0 mass parts of tryptophan, 1.5 to 5.0 mass parts of histidine, and 2.0 to 6.0 mass parts of arginine, wherein the total amount of these amino acids is 100 mass parts.
摘要翻译：提供了可以促进脂肪燃烧，提高耐力并减少例如马拉松期间的疲劳的氨基酸组合物，并且可以减轻肥胖并增加抗压力。氨基酸组合物含有3.0〜10.0质量份的天冬氨酸，2.5〜9.0质量份的苏氨酸，2.0〜9.5质量份的丝氨酸，12.0〜40.0质量份的谷氨酸，7.0〜20.0质量份的脯氨酸，0.5〜4.5 甘氨酸的质量份，丙氨酸1.0〜4.5质量份，缬氨酸3.0〜12.0质量份，胱氨酸0.1〜0.8质量份，甲硫氨酸1.5〜5.0质量份，异亮氨酸2.0〜8.0质量份，异亮氨酸5.0〜15.0质量份的亮氨酸，3.0〜10.0质量份的酪氨酸，3.0〜10.0质量份的苯丙氨酸，4.0〜15.0质量份的赖氨酸，0.8〜4.0质量份的色氨酸，1.5〜5.0质量份的组氨酸和2.0〜6.0质量份的精氨酸，其中这些氨基酸的总量为100质量份。

13. 发明申请

US20100094061A1 Stat3 phosphorylation inhibitor and notch1 expression inhibitor 有权
标题翻译： Stat3磷酸化抑制剂和缺口1表达抑制剂
公开(公告)号：US20100094061A1
公开(公告)日：2010-04-15
申请号：US11665375
申请日：2005-10-13
申请人： Bang Luu , Ellane Mohier , Masashi Yamada , Hiroto Suzuki
发明人： Bang Luu , Ellane Mohier , Masashi Yamada , Hiroto Suzuki
IPC分类号： C07C49/543
CPC分类号： A61K31/07 , A61K31/045 , A61K31/122
摘要： The present invention relates to an agent for suppressing STATS phosphorylation and for suppressing Notch1 expression comprising as an active ingredient a compound represented by the following formula (1): wherein R1, R2 and R3 each independently represents a hydrogen atom or a methyl group; and X represents a linear or branched alkyl, alkylene or alkenylene group having 10 to 28 carbon atoms.
摘要翻译：本发明涉及用于抑制STATS磷酸化和抑制Notch1表达的药剂，其包含作为活性成分的下式（1）表示的化合物：其中R1，R2和R3各自独立地表示氢原子或甲基; X表示碳原子数为10〜28的直链或支链烷基，亚烷基或亚烯基。

14. 发明申请

US20090299395A1 ULTRASONIC VIBRATION APPARATUS 有权
标题翻译：超声波振动装置
公开(公告)号：US20090299395A1
公开(公告)日：2009-12-03
申请号：US12132041
申请日：2008-06-03
申请人： Yuji Hirai , Masashi Yamada , Machiko Koshigoe
发明人： Yuji Hirai , Masashi Yamada , Machiko Koshigoe
IPC分类号： A61B17/32
CPC分类号： H01L41/0835 , A61B17/320092 , A61B2017/320088 , B06B1/0611
摘要： An ultrasonic vibration apparatus includes a vibrator, wherein the vibrator includes at least two vibration elements to generate ultrasonic vibration when a driving voltage is applied to the vibration elements, at least three electrode portions wherein the vibration elements and the electrode portions is alternately arranged side by side in a vibrating direction, at least the three electrode portions includes at least two first electrode portions and at least one second electrode portion alternately arranged in the vibrating direction, the vibrator integrally vibrates ultrasonically in the vibrating direction when the driving voltage is applied to the first electrode portions and the second electrode portion, and a bridging portion coupling and electrically connecting two first electrode portions of at least the two first electrode portions with each other, and the ultrasonic vibration apparatus further includes an anti-vibration portion to suppress vibration of the bridging portion in any other direction except the vibrating direction.
摘要翻译：一种超声波振动装置，其特征在于，振子具有至少2个振动元件，在对振动元件施加驱动电压时产生超声波振动，至少3个电极部分，其中振动元件和电极部分交替布置在至少三个电极部分包括至少两个第一电极部分和沿振动方向交替布置的至少一个第二电极部分，当驱动电压施加到振动方向时，振动器在振动方向上一体地振动超声波第一电极部分和第二电极部分，以及将至少两个第一电极部分的两个第一电极部分彼此耦合并电连接的桥接部分，并且超声波振动装置还包括防振部分，桥接部分除振动方向外的任何其他方向。

15. 发明申请

US20090036542A1 Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same 失效
标题翻译：对苯二酚长链衍生物和/或苯氧基长链衍生物和药物组成相同
公开(公告)号：US20090036542A1
公开(公告)日：2009-02-05
申请号：US11816625
申请日：2006-02-23
申请人： Bang Luu , Dominique Bagnard , Mazen Hanbali , Masashi Yamada , Hiroto Suzuki
发明人： Bang Luu , Dominique Bagnard , Mazen Hanbali , Masashi Yamada , Hiroto Suzuki
IPC分类号： A61K31/09 , C07C43/23 , C07C39/11 , A61K31/05 , A61P25/00
CPC分类号： C07C217/84 , C07C39/08 , C07C39/11 , C07C43/2055 , C07C43/23
摘要： The present invention provides compounds represented by formula (1) shown below: (wherein R1, R2, R3, R4, and R5 are each individually selected from among a hydrogen atom, methyl group, acetyl group, hydroxyl group, and alkoxy group; and X represents an alkylene group or alkenylene group); and compounds represented by formula (2) shown below: (wherein R6, R7, R8, R9, and R10 are each individually selected from among a hydrogen atom, alkyl group, acetyl group, hydroxyl group, and alkoxy group; A represents an oxygen atom or NH, and m is 0 or 1; and Y represents an alkylene group or alkenylene group, and Z represents a hydrogen atom or hydroxyl group).The compounds of the present invention are useful for preventing or treating brain dysfunctions, motor dysfunctions, or urinary dysfunctions caused by the degeneration and/or loss of the central nervous system or peripheral nervous system cells.
摘要翻译：本发明提供下述式（1）所示的化合物：（其中R1，R2，R3，R4和R5分别选自氢原子，甲基，乙酰基，羟基和烷氧基;以及 X表示亚烷基或亚烯基）; 和式（2）表示的化合物：（其中R 6，R 7，R 8，R 9和R 10各自独立地选自氢原子，烷基，乙酰基，羟基和烷氧基; A表示氧原子或NH，m为0或1; Y表示亚烷基或亚烯基，Z表示氢原子或羟基。本发明的化合物可用于预防或治疗脑功能障碍，运动功能障碍或由中枢神经系统或周围神经系统细胞的退化和/或丧失引起的尿功能障碍。

16. 发明申请

US20080312336A1 Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder 审中-公开
标题翻译：糖尿病血管疾病和呼吸系统疾病的预防和/或治疗剂
公开(公告)号：US20080312336A1
公开(公告)日：2008-12-18
申请号：US11913256
申请日：2005-11-24
申请人： Keisuke Satoh , Motoaki Saito , Bang Luu , Masashi Yamada , Hiroto Suzuki
发明人： Keisuke Satoh , Motoaki Saito , Bang Luu , Masashi Yamada , Hiroto Suzuki
IPC分类号： A61K31/122 , A61P11/00 , A61P9/00
CPC分类号： A61K31/122
摘要： The present invention provides preventive and/or therapeutic agents for either one, or both, of a diabetic vascular disorder and a diabetic respiratory disorder comprising, as an active ingredient, a cyclohexenone long chain alcohol compound represented by the following formula (1): [wherein R1, R2, and R3 each represent a hydrogen atom or a methyl group, and X represents a linear or branched C10-C28 alkylene or alkenylene group].Since the cyclohexenone long chain alcohol of formula (1) improves diabetic vascular smooth muscle contraction and bronchial smooth muscle contraction, it is useful as a preventive and/or therapeutic agent for a diabetic vascular disorder or a respiratory disorder.
摘要翻译：本发明提供糖尿病性血管疾病和糖尿病性呼吸系统疾病中的任一种或两者的预防和/或治疗剂，其包含作为活性成分的由下式（1）表示的环己烯酮长链醇化合物：[ 其中R 1，R 2和R 3各自表示氢原子或甲基，X表示直链或支链C 10 -C 28亚烷基或亚烯基]。由于式（1）的环己烯酮长链醇改善糖尿病血管平滑肌收缩和支气管平滑肌收缩，因此它可用作糖尿病血管病或呼吸障碍的预防和/或治疗剂。

17. 发明授权

US07235700B2 Process for producing cyclohexenone long-chain alcohols 有权
标题翻译：生产环己烯酮长链醇的方法
公开(公告)号：US07235700B2
公开(公告)日：2007-06-26
申请号：US10550305
申请日：2003-03-28
申请人： Bang Luu , Patrick Neuberg , Delphine Trancard , Masashi Yamada , Yukio Ohshiba , Hiroto Suzuki
发明人： Bang Luu , Patrick Neuberg , Delphine Trancard , Masashi Yamada , Yukio Ohshiba , Hiroto Suzuki
IPC分类号： C07C45/00
CPC分类号： C07C49/753 , C07C45/511 , C07C45/513 , C07C45/68 , C07C45/71 , C07C49/713
摘要： A process for producing cyclohexenone long-chain alcohol represented by the following formula (1): (wherein A represents a C10-C18 alkylene or alkenylene group, and each of R1, R2, and R3 individually represents hydrogen or methyl), comprising reacting a 3-alkoxy-2-cyclohexen-1-one derivative represented by the following formula (2): (wherein R1, R2, and R3 have the same meanings as above, and R4 represents a C1-C5 alkyl group) with a Grignard's reagent prepared by protecting the hydroxyl groups of C10-C18 ω-halogenoalcohol through silylation, and hydrolyzing the resultant reaction product. The process of the present invention for producing cyclohexenone long-chain alcohol requires a reduced number of reaction steps, can be performed with ease and with reduced production cost, and thus finds utility in the industry
摘要翻译：由下式（1）表示的生产环己烯酮长链醇的方法：（其中A表示C 10 -C 18亚烷基或亚烯基，R 1，R 2， R 2和R 3各自独立地表示氢或甲基），包括使由下式（2）表示的3-烷氧基-2-环己烯-1-酮衍生物：其中R ^{1，R 2，R 3和R 3具有与上述相同的含义，R 4表示C 1 -C 5烷基组），通过甲硅烷基化保护C10-C18ω-卤代醇的羟基制备的格氏试剂，并水解所得的反应产物。本发明用于生产环己烯酮长链醇的方法需要减少数量的反应步骤，可以容易地进行并降低生产成本，从而在工业中发挥作用}

18. 发明申请

US20070031157A1 Optical communication transmitter, optical communication receiver, optical communication system, and communication apparatus 有权
标题翻译：光通信发射机，光通信接收机，光通信系统和通信装置
公开(公告)号：US20070031157A1
公开(公告)日：2007-02-08
申请号：US11499413
申请日：2006-08-04
申请人： Masashi Yamada , Kousuke Nakamura
发明人： Masashi Yamada , Kousuke Nakamura
IPC分类号： H04B10/04 , H04B10/12
CPC分类号： H04B10/1141 , H04B10/116
摘要： In one inventive aspect, a transmitter is provided. In the transmitter, a modulator supplies an electrical current based on a digital transmission electrical signal to a white LED, which emits light including a plurality of wavelengths into the air. A light detector separates a light signal component having a blue wavelength from the emitted light using an optical filter and converts the signal component to a monitoring electrical signal. A waveform control circuit outputs a control signal so that the time delay of the waveform of the monitoring signal with respect to the waveform of the transmission electrical signal is less than or equal to a predetermined value. The modulator corrects the amount of the electrical current supplied to the white LED on the basis of the control signal. In another inventive aspect, a receiver is provided. In the receiver, an optical filter separates a light signal component having a blue wavelength and a light detector detects substantially only the light signal component having a blue wavelength.
摘要翻译：在一个发明方面，提供一种发射机。在发射机中，调制器将基于数字传输电信号的电流提供给白光LED，该LED将多个波长的光发射到空气中。光检测器使用滤光器将具有蓝色波长的光信号分量与发射光分离，并将该信号分量转换成监视电信号。波形控制电路输出控制信号，使得监视信号的波形相对于发送电信号的波形的时间延迟小于或等于预定值。调制器根据控制信号校正提供给白色LED的电流量。在另一个发明方面，提供一种接收器。在接收机中，光学滤波器分离具有蓝色波长的光信号分量，光检测器基本上仅检测具有蓝色波长的光信号分量。

19. 发明申请

US20060203642A1 Optical information recording device, optical information recording method, and signal processing circuit 失效
标题翻译：光信息记录装置，光信息记录方法和信号处理电路
公开(公告)号：US20060203642A1
公开(公告)日：2006-09-14
申请号：US11361884
申请日：2006-02-24
申请人： Hiroya Kakimoto , Mitsuo Sekiguchi , Isao Matsuda , Masashi Yamada
发明人： Hiroya Kakimoto , Mitsuo Sekiguchi , Isao Matsuda , Masashi Yamada
IPC分类号： G11B5/09
CPC分类号： G11B20/10009 , G11B7/0062 , G11B20/10055 , G11B20/10296 , G11B20/10333 , G11B20/1816
摘要： It is an object of the present invention to provide a recording condition closer to an optimum even for a medium unknown to a drive, and more particularly to provide a method especially effective when applied to code identification methods, such as PRML, wherein codes are identified based on amplitude information of an RF signal. In order to accomplish the object, an RF signal received from a photo-receiving part 108 of a pickup is converted into sampling data by an A/D converter 300, and a Viterbi decoder 302 performs code determination using the sampling data. Codes included in a reproduction signal are then determined by synchronizing recording pulses with the reproduction signal using the result of the code determination. Then, the result is used to specify a part to be detected in the codes, and finally an amplitude of the specified part is detected.
摘要翻译：本发明的目的是提供即使对于驱动器未知的介质更接近最佳的记录条件，更具体地说，提供一种在应用于诸如PRML的代码识别方法时特别有效的方法，其中代码被识别基于RF信号的幅度信息。为了实现该目的，从A / D转换器300将从拾取器的光接收部分108接收到的RF信号转换成采样数据，维特比解码器302使用采样数据执行代码确定。然后通过使用代码确定的结果，使记录脉冲与再现信号同步来确定包含在再现信号中的代码。然后，结果用于指定要在代码中检测的部分，最后检测指定部分的幅度。

20. 发明授权

US06844453B2 1,2-Dioxetane derivatives and reagents employing them 有权
标题翻译： 1,2-二氧杂环丁烷衍生物和使用它们的试剂
公开(公告)号：US06844453B2
公开(公告)日：2005-01-18
申请号：US10798338
申请日：2004-03-12
申请人： Masakatsu Matsumoto , Nobuko Watanabe , Masashi Yamada
发明人： Masakatsu Matsumoto , Nobuko Watanabe , Masashi Yamada
IPC分类号： C07D321/00 , C07D493/04 , C07F7/18 , C07D305/14
CPC分类号： C07D493/04 , C07D321/00 , C07F7/1804
摘要： A 1,2-dioxetane derivative of the formula (I): wherein Ar is an aryl group which may have an alkyl group, an aryl group, a halogen atom, an alkoxyl group, a carboxyl group, a formyl group, an alkyl ester, an aryl ester, an alkylketone, an arylketone or a hetero ring bonded thereto, X is a substituent capable of labeling an organic compound or a biological molecule, or an ester, Y is a hydrogen atom, an acyl group or a group of the formula —Si(R4R5R6) (wherein each of R4, R5 and R6 which are independent of one another, is an alkyl group or an aryl group), Z is an alkyl group, an aryl group, an oxygen atom, a sulfur atom, a carbonyl group, —(CO)—O—, —O—(CO)—, —NH—, —NH—CO—, —CO—NH—, —OSi(R7R8)— (wherein each of R7 and R8 which are independent of each other, is an alkyl group or aryl group) or a group of the formula —(R9R10)SiO— (wherein each of R9 and R10 which are independent of each other, is an alkyl group or an aryl group), each of R1 and R2 is an alkyl group or an aryl group, and R3 is a spacer.
摘要翻译：式（I）的1,2-二氧杂环丁烷衍生物：其中Ar是可以具有烷基，芳基，卤素原子，烷氧基，羧基，甲酰基，烷基酯的芳基，芳基酯，烷基酮，芳基酮或与其结合的杂环，X是能够标记有机化合物或生物分子的取代基或酯，Y是氢原子，酰基或基团的基团式-Si（R4R5R6）（其中R4，R5和R6各自独立地为烷基或芳基），Z为烷基，芳基，氧原子，硫原子，羰基， - （CO）-O-，-O-（CO） - ， - NH - ， - NH-CO - ， - CO-NH-，-OSi（R7R8） - （其中R7和R8各自相互独立，为烷基或芳基）或式 - （R9R10）SiO - （其中R 9和R 10各自独立地为烷基或芳基）的基团， R 1和R 2各自是烷基或芳基，R 3 是间隔物。

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