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11. 发明授权

US5962978A Apparatus for automatically degaussing a color picture tube in response to a power conservation mode 失效
标题翻译：用于响应功率节省模式自动消磁彩色显像管的装置
公开(公告)号：US5962978A
公开(公告)日：1999-10-05
申请号：US943569
申请日：1997-10-03
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： H04N9/29 , H01F13/00
CPC分类号： H04N9/29
摘要： An automatic degaussing circuit for a color picture tube (CPT) capable of automatically degaussing the CPT when a power conservation mode is released in a monitor having a power conservation function. The degaussing circuit includes a degaussing coil for eliminating electromagnetic waves produced from the CPT, a power conservation mode detecting section for detecting the release of the power conservation mode in accordance with a power conservation mode signal of the CPT inputted thereto and providing a degaussing control signal for controlling the operation of the degaussing coil if the release of the power conservation mode is detected, and a degaussing coil driving section for driving the degaussing coil for a predetermined time in accordance with the degaussing control signal when the power conservation mode is released.
摘要翻译：一种用于彩色显像管（CPT）的自动消磁电路，当在具有功率节省功能的监视器中释放节能模式时，能够自动消磁CPT。消磁电路包括用于消除由CPT产生的电磁波的消磁线圈，功率节省模式检测部分，用于根据输入的CPT的功率节省模式信号来检测功率节省模式的释放，并提供消磁控制信号如果检测到省电模式的释放，则用于控制消磁线圈的操作;以及消磁线圈驱动部分，用于在释放节电模式时根据消磁控制信号驱动消磁线圈预定时间。

12. 发明授权

US09261496B2 Device for high throughput investigations of multi-cellular interactions 有权
标题翻译：用于多细胞相互作用的高通量调查的装置
公开(公告)号：US09261496B2
公开(公告)日：2016-02-16
申请号：US13876293
申请日：2011-09-29
申请人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
发明人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
IPC分类号： C12M1/34 , C12M3/00 , G01N33/50 , B01L3/00 , C12M3/06 , C12M1/00 , C12M1/12
CPC分类号： G01N33/5008 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , C12M23/16 , C12M23/22 , C12M25/14 , C12M29/04 , G01N33/5011 , G01N33/5029 , G01N33/5058 , G01N33/5064
摘要： Provided herein are microfluidic devices that can be used as a 3D bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts. As shown herein, when the device is plated with cells such as endothelial cells, new blood vessels grow in the gel, which is thick enough for the cells to grow in three dimensions. Other channels, e.g., fluid channels, allow drugs or biological material to be exposed to the 3D cell growth. Cells, such as endothelial cells, can be cultured and observed as they grow on the surface of a 3D gel scaffold, where e.g., rates of angiogenesis can be measured, as well as intervascularization and extravascularization of cancerous cells.
摘要翻译：本文提供的微流体装置可用作3D生物测定，例如用于药物筛选，个性化医学，组织工程，伤口愈合和其它应用。该装置在小聚合物嵌段中具有一系列通道（例如，小的流体通道），其中一个或多个通道可以填充生物相关凝胶，例如通过柱保持在适当位置的胶原。如本文所示，当该装置镀有诸如内皮细胞的细胞时，新的血管在凝胶中生长，其足够厚以使细胞在三维中生长。其他通道，例如流体通道，允许药物或生物材料暴露于3D细胞生长。可以在3D凝胶支架的表面上生长细胞，例如内皮细胞，并且观察细胞，其中例如可以测量血管发生的速率，以及癌细胞的血管间血管形成和血管外再造。

13. 发明授权

US08623620B2 Microorganism which produces L-amino acid and method for producing L-amino acid using the same 有权
标题翻译：产生L-氨基酸的微生物和使用其生产L-氨基酸的方法
公开(公告)号：US08623620B2
公开(公告)日：2014-01-07
申请号：US13254072
申请日：2010-02-16
申请人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
发明人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae
IPC分类号： C12N9/24
CPC分类号： C12P13/04 , C07K14/26 , C12N9/1205 , C12P13/08
摘要： The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.
摘要翻译：本发明涉及属于埃希氏菌属的微生物。以及使用其制造L-氨基酸的方法。属于埃希氏菌属的微生物具有蔗糖同化性和L-氨基酸产生能力，其通过将编码蔗糖同化微生物的蔗糖代谢酶的基因导入属于埃希氏菌属的蔗糖非同化微生物而获得。具有L-氨基酸生产能力和蔗糖PTS（磷酸烯醇丙酮酸依赖性蔗糖磷酸转移酶系统）活性。

14. 发明授权

US08574874B2 Microorganisms for producing L-amino acids and process for producing L-amino acids using them 有权
标题翻译：用于生产L-氨基酸的微生物和使用它们生产L-氨基酸的方法
公开(公告)号：US08574874B2
公开(公告)日：2013-11-05
申请号：US12743675
申请日：2010-02-11
申请人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae , Hyo Jin Kim , Keun Chul Lee , Young Bin Hwang , Kyu Soo Cho , Hye Min Park , Hyun Ah Kim
发明人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae , Hyo Jin Kim , Keun Chul Lee , Young Bin Hwang , Kyu Soo Cho , Hye Min Park , Hyun Ah Kim
IPC分类号： C12P13/22
CPC分类号： C12P13/04 , C12N9/1205 , C12N9/2488 , C12Y207/01007 , C12Y302/01048
摘要： The present invention relates to a transformed microorganism producing an L-amino acid using sucrose as a main carbon source, and a method for producing an L-amino acid using the same.
摘要翻译：本发明涉及使用蔗糖作为主要碳源生产L-氨基酸的转化微生物，以及使用该氨基酸生产L-氨基酸的方法。

15. 发明授权

US08091333B2 Flexible wire for removing scale in pipe 有权
标题翻译：用于去除管道中的垢的柔性线
公开(公告)号：US08091333B2
公开(公告)日：2012-01-10
申请号：US12675559
申请日：2008-09-02
申请人： Kwang Ho Lee
发明人： Kwang Ho Lee
IPC分类号： D02G3/02 , D02G3/22
CPC分类号： B08B9/045 , B08B7/02 , D07B5/00
摘要： Provided is a flexible wire to be inserted in a pipe and rotated in a high speed to remove scales in the pipe by striking the scales. The flexible wire includes a main wire line which is formed by alternately winding a central wire line with clockwise and counterclockwise wires along a longitudinal direction of the central wire line, an auxiliary wire line which is a single line having a diameter smaller than that of the main wire line and extends in a longitudinal direction of the main wire line, and an outermost wire which winds the auxiliary wire line so as to bind the auxiliary wire line and the main wire line.
摘要翻译：本发明提供一种插入管中的柔性线，并且高速旋转以通过冲击鳞片去除管中的鳞屑。柔性线包括主线，其通过沿着中心线线的纵向交替地绕中心线线顺时针和逆时针方向地缠绕而形成，辅助线线是直径小于主线路并且在主线路的纵向方向上延伸，并且最外面的线材缠绕辅助线路线以使辅助线路线路和主线路线路结合。

16. 发明申请

US20110189739A1 ESCHERICHIA COLI STRAIN WITH ENHANCED L-THREONINE PRODUCTIVITY AND METHOD OF PRODUCING L-THREONINE USING THE SAME 有权
标题翻译：具有增强的L-苏氨酸生产力的ESCHERICHIA COLI菌株和使用该柠檬酸生产L-赖氨酸的方法
公开(公告)号：US20110189739A1
公开(公告)日：2011-08-04
申请号：US12812203
申请日：2009-01-07
申请人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
发明人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
IPC分类号： C12P13/08 , C12N1/21
CPC分类号： C12P13/08 , C12N9/1085 , C12N9/88
摘要： An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
摘要翻译：公开了其中染色体上的磷酸烯醇式丙酮酸羧化酶（ppc）基因的启动子被半胱氨酸合成酶（cysK）基因的启动子取代的产生L-苏氨酸的大肠杆菌以及通过使用它们产生L-苏氨酸的方法。重组大肠杆菌可以以高产率生产L-苏氨酸，因此可广泛用于医药，制药和饲料工业，特别是用于动物饲料。

17. 发明申请

US20110111466A1 Microorganisms for Producing L-Amino Acids and Process for Producing L-Amino Acids Using Them 有权
标题翻译：用于生产L-氨基酸的微生物及其生产L-氨基酸的方法
公开(公告)号：US20110111466A1
公开(公告)日：2011-05-12
申请号：US12743675
申请日：2010-02-11
申请人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae , Hyo Jin Kim , Keun Chul Lee , Young Bin Hwang , Kyu Soo Cho , Hye Min Park , Hyun Ah Kim
发明人： Jae Yeong Ju , Kwang Ho Lee , Hyun Ae Bae , Hyo Jin Kim , Keun Chul Lee , Young Bin Hwang , Kyu Soo Cho , Hye Min Park , Hyun Ah Kim
IPC分类号： C12P13/22 , C12N1/21 , C12P13/08 , C12P13/06 , C12P13/12
CPC分类号： C12P13/04 , C12N9/1205 , C12N9/2488 , C12Y207/01007 , C12Y302/01048
摘要： The present invention relates to a transformed microorganism producing an L-amino acid using sucrose as a main carbon source, and a method for producing an L-amino acid using the same.
摘要翻译：本发明涉及使用蔗糖作为主要碳源产生L-氨基酸的转化微生物，以及使用该氨基酸生产L-氨基酸的方法。

18. 发明授权

US07078222B2 Microorganism for producing riboflavin and method for producing riboflavin using the same 有权
标题翻译：用于生产核黄素的微生物及使用其生产核黄素的方法
公开(公告)号：US07078222B2
公开(公告)日：2006-07-18
申请号：US10454220
申请日：2003-06-04
申请人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
发明人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
IPC分类号： C12N1/20 , C12P25/00
CPC分类号： C12R1/125 , C12P25/00
摘要： Riboflavin-producing Bacillus subtilis which is resistant to threonine analogue, and a method for producing riboflavin using the Bacillus subtilis are provided.The subject Bacillus subtilis referred to as Bacillus subtilis CJKB0002 has the accession number KCCM-10446, having been deposited in Korean Culture Center of Microorganisms (KCCM), 361-221, Yurim B/D, Hongie-1-dong, Seodaemun-gut, Seoul 120-091 Republic of Korea, on Nov. 18, 2002.
摘要翻译：提供了对苏氨酸类似物具有抗性的产生核黄素的枯草芽孢杆菌，以及使用枯草芽孢杆菌生产核黄素的方法。被称为枯草芽孢杆菌CJKB0002的枯草芽孢杆菌具有保藏在韩国微生物培养中心（KCCM），361-221，Yurim B / D，Hongie-1-dong，Seodaemun-gut的登录号KCCM-10446，汉城120-091大韩民国，2002年11月18日。

19. 发明授权

US5929083A Oxazolidinone derivatives and a method for the preparation thereof and an antibacterial composition containing the same 失效
标题翻译：恶唑烷酮衍生物及其制备方法和含有它们的抗菌组合物
公开(公告)号：US5929083A
公开(公告)日：1999-07-27
申请号：US891835
申请日：1997-07-14
申请人： Yeo Hong Yoon , Hak Sung Kim , Kwang Ho Lee , Kwang Hyuk Lee , Jin Ah Kang , Youn Ha Lee
发明人： Yeo Hong Yoon , Hak Sung Kim , Kwang Ho Lee , Kwang Hyuk Lee , Jin Ah Kang , Youn Ha Lee
IPC分类号： C07D413/10 , C07D413/14 , C07D491/10 , A61K31/435 , C07D221/20 , C07D221/22
CPC分类号： C07D413/10 , C07D491/10
摘要： An antibacterially effective compound of formula I: ##STR1## or a salt or hydrate thereof in which R1, R2, R3, R4, R5, X are as defined herein. Further, a process for producing the compound of formula I and an antibacterial composition containing antibacterially effective amount of the compound of formula I are disclosed.
摘要翻译：式I的抗菌有效化合物或其盐或水合物，其中R 1，R 2，R 3，R 4，R 5，X如本文所定义。此外，公开了制备式I化合物的方法和含有抗菌有效量的式I化合物的抗菌组合物。

20. 发明授权

US08455237B2 Escherichia coli strain with phosphoenolpyruvate carboxylase promoter replaced with cysteine synthase promoter and method of enhanced production of L-threonine using the same 有权
标题翻译：具有用半胱氨酸合成酶启动子取代的具有磷酸烯醇丙酮酸羧化酶启动子的大肠杆菌菌株和使用其同时增强L-苏氨酸生产的方法
公开(公告)号：US08455237B2
公开(公告)日：2013-06-04
申请号：US12812203
申请日：2009-01-07
申请人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
发明人： Kwang Ho Lee , Jae Yeong Ju , Ji Sun Lee , Young Bin Hwang , Sung Hoo Jhon , Eun Sung Koh , Chul Ha Kim , Soo An Shin
IPC分类号： C12N1/20
CPC分类号： C12P13/08 , C12N9/1085 , C12N9/88
摘要： An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
摘要翻译：公开了其中染色体上的磷酸烯醇式丙酮酸羧化酶（ppc）基因的启动子被半胱氨酸合成酶（cysK）基因的启动子取代的产生L-苏氨酸的大肠杆菌以及通过使用它们产生L-苏氨酸的方法。重组大肠杆菌可以以高产率生产L-苏氨酸，因此可广泛用于医药，制药和饲料工业，特别是用于动物饲料。

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