专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US6114526A Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases 有权
标题翻译：杂环化合物，其制备方法和含有它们的药物组合物及其在治疗糖尿病和相关疾病中的用途
公开(公告)号：US6114526A
公开(公告)日：2000-09-05
申请号：US353286
申请日：1999-07-14
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Ranga Madhavan Gurram , Rajagopalan Ramanujam , Ranjan Chakrabarti , Sarma K.S. Pakala
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Ranga Madhavan Gurram , Rajagopalan Ramanujam , Ranjan Chakrabarti , Sarma K.S. Pakala
IPC分类号： C07D239/36 , C07D239/46 , C07D239/88 , C07D241/34 , C07D277/34 , C07D413/12 , C07D417/12 , C07D471/04 , C07D495/04 , C07D239/02 , C07D241/00
CPC分类号： C07D239/36 , C07D239/47 , C07D239/88 , C07D277/34 , C07D413/12 , C07D417/12 , C07D471/04 , C07D495/04
摘要： The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinedione derivatives of the general formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them ##STR1##
摘要翻译：本发明涉及新的抗糖尿病化合物，其互变异构形式，其衍生物，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。本发明特别涉及通式（I）的新的唑烷二酮衍生物及其药学上可接受的盐，药学上可接受的溶剂合物和含有它们的药物组合物

12. 发明授权

US06444816B1 Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof 失效
标题翻译：融合的7-氧代 - 嘧啶基化合物，其制备，组成和用途
公开(公告)号：US06444816B1
公开(公告)日：2002-09-03
申请号：US09507373
申请日：2000-02-18
申请人： Saibal Kumar Das , Papi Reddy Purma , Venkateswarlu Akella , Rajagopalan Ramanujam , Ranjan Chakrabarti , Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli
发明人： Saibal Kumar Das , Papi Reddy Purma , Venkateswarlu Akella , Rajagopalan Ramanujam , Ranjan Chakrabarti , Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli
IPC分类号： C07D23902
CPC分类号： C07C217/22 , C07C237/32 , C07C247/04 , C07D239/36 , C07D239/90
摘要： The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their analogs, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to novel intermediates, processes for their preparation and their use in the preparation of compounds of formula (I).
摘要翻译：本发明涉及新型抗肥胖和低胆固醇血症化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。更具体地，本发明涉及通式（I）的新型β-芳基-α-氧代取代的烷基羧酸，其衍生物，它们的类似物，其互变异构形式，它们的立体异构体，它们的多晶型物，其药学上可接受的盐，它们的药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。本发明还涉及制备上述新化合物，其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的溶剂化物和含有它们的药物组合物的方法。本发明还涉及新型中间体，其制备方法及其在制备式（I）化合物中的用途。

13. 发明授权

US6130214A Benzothiazin and benzoxazin derivatives; their preparation and uses 失效
标题翻译：苯并噻嗪和苯并恶嗪衍生物; 他们的准备和使用
公开(公告)号：US6130214A
公开(公告)日：2000-10-10
申请号：US179141
申请日：1998-10-26
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
IPC分类号： C07C235/48 , C07C323/62 , C07C327/48 , C07D239/90 , C07D265/22 , C07D279/08 , A61K31/54 , A61K31/535 , C07D265/12 , C07D279/16
CPC分类号： C07C323/62 , C07C235/48 , C07C327/48 , C07D239/90 , C07D265/22 , C07D279/08
摘要： The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel .beta.-aryl-.alpha.-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. ##STR1##
摘要翻译：本发明涉及新型抗肥胖和低胆固醇血症化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。更具体地说，本发明涉及通式（I）的新型β-芳基-α-氧基取代的烷基羧酸，其衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，它们的药学上可接受的盐，它们的药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。

14. 发明授权

US6011036A Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：具有抗糖尿病降血脂降压特性的杂环化合物的制备方法和含有它们的药物组合物
公开(公告)号：US6011036A
公开(公告)日：2000-01-04
申请号：US982962
申请日：1997-12-02
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Ranga Madhavan Gurram , Rajagopalan Ramanujam , Ranjan Chakrabarti
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Ranga Madhavan Gurram , Rajagopalan Ramanujam , Ranjan Chakrabarti
IPC分类号： C07D265/22 , C07D277/20 , C07D277/34 , C07D413/12 , C07D417/12 , A61K31/50 , A61K31/535 , C07D237/30 , C07D265/02
CPC分类号： C07D417/12 , C07D265/22 , C07D277/20 , C07D277/34 , C07D413/12
摘要： The present invention relates to novel antidiabetic compounds, their tautomeric forms, their analogues, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinedione compounds of the general formula (I), and their analogues, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. ##STR1##
摘要翻译：本发明涉及新型抗糖尿病化合物，其互变异构形式，其类似物，其衍生物，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和含有它们的药学上可接受的组合物。本发明特别涉及通式（I）的新的唑烷二酮化合物及其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的溶剂化物和含有它们的药物组合物。

15. 发明授权

US06313113B1 Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：具有抗糖尿病，降血脂和抗高血压性质的杂环化合物，其制备方法和含有它们的药物组合物
公开(公告)号：US06313113B1
公开(公告)日：2001-11-06
申请号：US08982911
申请日：1997-12-02
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
IPC分类号： A61K31536
CPC分类号： C07D417/12 , C07D265/22 , C07D277/20 , C07D277/34 , C07D413/12
摘要： The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their analogues, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinediones of the general formula (I), their analogues, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them
摘要翻译：本发明涉及新型抗糖尿病化合物，其互变异构形式，其衍生物，其类似物，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和含有它们的药学上可接受的组合物。本发明特别涉及通式（I）的新型唑烷二酮类，其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的溶剂合物和含有它们的药物组合物

16. 发明授权

US06846824B2 Bicyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：双环化合物及其在药物中的用途; 其制备方法和含有它们的药物组合物
公开(公告)号：US06846824B2
公开(公告)日：2005-01-25
申请号：US09816584
申请日：2001-03-23
申请人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rajagopalan Ramanujam , Ranjan Chakrabarti , Javed Iqbal , Ranga Madhavan Gurram
发明人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rajagopalan Ramanujam , Ranjan Chakrabarti , Javed Iqbal , Ranga Madhavan Gurram
IPC分类号： A61K9/08 , A61K9/10 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/538 , A61K31/5415 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/00 , A61P9/10 , A61P13/12 , A61P17/06 , A61P19/10 , A61P25/28 , C07D265/36 , C07D279/16 , C07D413/06 , A61K31/495 , C07D241/38
CPC分类号： C07D413/06 , A61K31/5415 , C07D265/36 , C07D279/16
摘要： Compounds of formula (I) its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates can be used to prevent or treat diabetes caused by insulin resistance or impaired glucose tolerance or complications of diabetes caused by insulin resistance or impaired glucose tolerance. The compounds can also be used to reduce cholesterol, body weight, blood glucose, triglycerides and free fatty acids in the blood.
摘要翻译：式（I）化合物其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐或其药学上可接受的溶剂化物可用于预防或治疗由胰岛素抵抗或糖耐量受损或由胰岛素抵抗引起的糖尿病并发症引起的糖尿病，葡萄糖耐量降低。该化合物也可用于降低血液中的胆固醇，体重，血糖，甘油三酯和游离脂肪酸。

17. 发明授权

US06331627B1 Intermediates of benzoxazinone derivatives and preparation thereof 失效
标题翻译：苯并恶嗪酮衍生物的中间体及其制备方法
公开(公告)号：US06331627B1
公开(公告)日：2001-12-18
申请号：US09610623
申请日：2000-07-05
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
IPC分类号： C07D27916
CPC分类号： C07C323/62 , C07C235/48 , C07C327/48 , C07D239/90 , C07D265/22 , C07D279/08
摘要： The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereo-somers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their analogs, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, novel intermediates and pharmaceutical compositions containing them.
摘要翻译：本发明涉及新型抗肥胖和低胆固醇血症化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。更具体地，本发明涉及通式（I）的新型β-芳基-α-氧代取代的烷基羧酸，其衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，其药学上可接受的盐，它们的药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。本发明还涉及制备上述新化合物，其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的盐可接受的溶剂合物，新型中间体和含有它们的药物组合物。

18. 发明授权

US6030973A Heterocyclic compounds having antidiabetic hypolipidemia and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：具有抗糖尿病血脂异常和抗高血压性质的杂环化合物，其制备方法和含有它们的药物组合物
公开(公告)号：US6030973A
公开(公告)日：2000-02-29
申请号：US135566
申请日：1998-08-17
申请人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
发明人： Vidya Bhushan Lohray , Braj Bhushan Lohray , Rao Bheema Paraselli , Rajagopalan Ramanujam , Ranjan Chakrabarti
IPC分类号： C07D265/22 , C07D277/20 , C07D277/34 , C07D413/12 , C07D417/12 , A61K31/505 , C07D239/91 , C07D239/92 , C07D279/08
CPC分类号： C07D417/12 , C07D265/22 , C07D277/20 , C07D277/34 , C07D413/12
摘要： The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their analogues, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinediones of the general formula (I), their analogues, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. ##STR1##
摘要翻译：本发明涉及新型抗糖尿病化合物，其互变异构形式，其衍生物，其类似物，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂化物和含有它们的药学上可接受的组合物。本发明特别涉及通式（I）的新型氮杂二醇，其类似物，其衍生物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，药学上可接受的溶剂合物和含有它们的药物组合物。

19. 发明授权

US06548666B1 Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：三环化合物及其在药物制备中的应用及含有它们的药物组合物
公开(公告)号：US06548666B1
公开(公告)日：2003-04-15
申请号：US09853176
申请日：2001-05-10
申请人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rao Bheema Paraselli , Ranga Madhavan Gurram
发明人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rao Bheema Paraselli , Ranga Madhavan Gurram
IPC分类号： C07D2448
CPC分类号： C07D413/06 , C07C59/64 , C07C69/734 , C07D265/28 , C07D265/38 , C07D279/22 , C07D279/26 , C07D417/06
摘要： A compound of Formula (Ig) The compounds may be used, inter alia, for preparing beta aryl-alpha-oxy substituted alkylcarboxylic acids.
摘要翻译：式（Ig）的化合物该化合物尤其用于制备β芳基-α-氧取代的烷基羧酸。

20. 发明授权

US06608194B1 Tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them 失效
标题翻译：三环化合物及其在医药中的应用其制备方法和含有它们的药物组合物
公开(公告)号：US06608194B1
公开(公告)日：2003-08-19
申请号：US09853177
申请日：2001-05-10
申请人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rao Bheema Paraselli , Ranga Madhavan Gurram
发明人： Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Channaveerappa Bajji , Shivaramayya Kalchar , Rao Bheema Paraselli , Ranga Madhavan Gurram
IPC分类号： C07D26538
CPC分类号： C07D413/06 , C07C59/64 , C07C69/734 , C07D265/28 , C07D265/38 , C07D279/22 , C07D279/26 , C07D417/06
摘要： A compound of Formula (Ih) The compounds may be used, inter alia, for preparing beta aryl-alpha-oxy substituted alkylcarboxylic acids.
摘要翻译：式（Ih）的化合物该化合物尤其用于制备β芳基-α-氧取代的烷基羧酸。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式