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11. 发明授权

US06815456B2 Heterocyclyloxy-, -thioxy- and -aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands 失效
标题翻译：作为5-羟基色胺-6配体的杂环氧基 - ， - 羟基 - 和 - 氨基苯唑衍生物
公开(公告)号：US06815456B2
公开(公告)日：2004-11-09
申请号：US10126598
申请日：2002-04-19
申请人： Ping Zhou , Boyd Lynn Harrison , Yanfang Li
发明人： Ping Zhou , Boyd Lynn Harrison , Yanfang Li
IPC分类号： A61K31445
CPC分类号： C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D409/14
摘要： The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor.

12. 发明授权

US06613781B2 Heterocyclylaklylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands 失效
标题翻译：杂环基甲基吲哚或杂环化合物作为5-羟基色胺-6配体
公开(公告)号：US06613781B2
公开(公告)日：2003-09-02
申请号：US10028487
申请日：2001-12-20
申请人： Ping Zhou , Michael Gerard Kelly , Yanfang Li
发明人： Ping Zhou , Michael Gerard Kelly , Yanfang Li
IPC分类号： A61K31454
CPC分类号： C07D401/14 , C07D401/06 , C07D409/14
摘要： The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor
摘要翻译：本发明提供式I化合物及其在治疗与5-HT 6受体有关或受其影响的病症中的用途

13. 发明授权

US08990157B2 Replication support for structured data 有权
标题翻译：对结构化数据的复制支持
公开(公告)号：US08990157B2
公开(公告)日：2015-03-24
申请号：US13299931
申请日：2011-11-18
申请人： Ping Zhou , Stephen Shepherd
发明人： Ping Zhou , Stephen Shepherd
IPC分类号： G06F17/30
CPC分类号： G06F17/30575
摘要： A method, system and computer readable storage medium for replicating structured data stored in a database. The method includes identifying the stored structured data, mapping the data to an unstructured data type, and sending the mapped data to one or more replicate databases as unstructured data.
摘要翻译：一种用于复制存储在数据库中的结构化数据的方法，系统和计算机可读存储介质。该方法包括识别存储的结构化数据，将数据映射到非结构化数据类型，以及将映射的数据作为非结构化数据发送到一个或多个复制数据库。

14. 发明申请

US20120317078A1 Replication Support for Structured Data 有权
标题翻译：复制支持结构化数据
公开(公告)号：US20120317078A1
公开(公告)日：2012-12-13
申请号：US13299931
申请日：2011-11-18
申请人： Ping Zhou , Stephen Shepherd
发明人： Ping Zhou , Stephen Shepherd
IPC分类号： G06F7/00
CPC分类号： G06F17/30575
摘要： A method, system and computer readable storage medium for replicating structured data stored in a database. The method includes identifying the stored structured data, mapping the data to an unstructured data type, and sending the mapped data to one or more replicate databases as unstructured data.
摘要翻译：一种用于复制存储在数据库中的结构化数据的方法，系统和计算机可读存储介质。该方法包括识别存储的结构化数据，将数据映射到非结构化数据类型，以及将映射的数据作为非结构化数据发送到一个或多个复制数据库。

15. 发明申请

US20120284383A1 CLOUD WORKLOAD MANAGEMENT WITH AUTOMATED WORKLOAD BIDDING 审中-公开
标题翻译：具有自动工作负载的云工作负载管理
公开(公告)号：US20120284383A1
公开(公告)日：2012-11-08
申请号：US13102538
申请日：2011-05-06
申请人： Clark A. Dudek , Phillip D. Jones , David B. Roberts , Adrian X. Rodriguez , Ian C. Tewksbury , Ping Zhou
发明人： Clark A. Dudek , Phillip D. Jones , David B. Roberts , Adrian X. Rodriguez , Ian C. Tewksbury , Ping Zhou
IPC分类号： G06F15/173
CPC分类号： G06F9/5072 , G06F9/5027
摘要： A computer program product is provided for managing workload in a computer system. Computer usable program code cause a first compute node to broadcast a workload bid request to a plurality of compute nodes, wherein the workload bid request includes workload parameters. The compute nodes each receive the request from the first compute node, and each compute node uses the workload parameters to calculate a cost of running the workload. One or more individual compute nodes within the plurality of compute nodes send a workload bid to the first compute node, wherein each workload bid includes the cost of running the workload on the individual compute node sending the workload bid. The first compute node receives and uses each workload bid to select a target compute node to run the workload, wherein the target compute node is selected from the individual compute nodes and the first compute node.
摘要翻译：提供了一种用于管理计算机系统中的工作负载的计算机程序产品。计算机可用程序代码导致第一计算节点向多个计算节点广播工作负荷出价请求，其中所述工作负荷出价请求包括工作负载参数。计算节点各自接收来自第一计算节点的请求，并且每个计算节点使用工作负载参数来计算运行工作负载的成本。多个计算节点内的一个或多个单独计算节点向第一计算节点发送工作负荷出价，其中每个工作负荷出价包括在发送工作量出价的个别计算节点上运行工作负荷的成本。第一计算节点接收并使用每个工作负荷出价来选择目标计算节点来运行工作负载，其中从各个计算节点和第一计算节点中选择目标计算节点。

16. 发明授权

US08221634B2 Process and apparatus for separating and recovering waste alkali from cyclohexane oxidation solution 有权
标题翻译：从环己烷氧化溶液中分离回收废碱的工艺和设备
公开(公告)号：US08221634B2
公开(公告)日：2012-07-17
申请号：US12358004
申请日：2009-01-22
申请人： Zhishan Bai , Zhuoqun Qian , Ji Ma , Ping Zhou , Yanhong Zhang , Hualin Wang
发明人： Zhishan Bai , Zhuoqun Qian , Ji Ma , Ping Zhou , Yanhong Zhang , Hualin Wang
IPC分类号： C07C49/00 , C07C29/20 , B01D21/00 , B01D35/18 , B01D11/00
CPC分类号： C07C45/33 , B01D17/0214 , C07C2601/14 , Y10S210/908 , C07C49/403
摘要： A process and an apparatus for separating and recovering waste alkali from a cyclohexane oxidation solution are provided. A gradient combination of the gravity separation technique, the vortex separation technique and the coalescence separation technique is used to carry out fine separation of the waste alkali liquor from the cyclohexane oxidation solution. The purified cyclohexane oxidation solution is fed into a down-stream apparatus. Most of the waste alkali liquor thus separated is recycled, while the remaining is expelled. The expelled waste alkali liquor is incinerated in an incinerator, followed by recovering the molten species using a pneumatic pulverization process.
摘要翻译：提供了一种用于从环己烷氧化溶液中分离和回收废碱的方法和装置。使用重力分离技术，涡流分离技术和聚结分离技术的梯度组合进行废碱液与环己烷氧化溶液的精细分离。将纯化的环己烷氧化溶液进料到下游装置中。大部分如此分离的废碱液体被回收，而其余的被排出。将排出的废碱液在焚化炉中焚烧，然后使用气动粉碎法回收熔融物质。

17. 发明授权

US07862819B2 Diacylglycerol O-acyltransferase 2α (DGAT2α) 有权
标题翻译：二酰基甘油O-酰基转移酶2α（DGAT2α）
公开(公告)号：US07862819B2
公开(公告)日：2011-01-04
申请号：US10446441
申请日：2003-05-27
申请人： Sylvaine Cases , Robert V. Farese , Scot J. Stone , Ping Zhou
发明人： Sylvaine Cases , Robert V. Farese , Scot J. Stone , Ping Zhou
IPC分类号： A61K39/395 , C12N9/10 , C12N15/09
CPC分类号： C12N9/1029 , A01K2217/05 , A61K38/00 , A61K2039/505 , C12Y203/0102 , C12Y203/01022
摘要： Nucleic acid compositions encoding mammalian DGAT2α polypeptide products with diglyceride acyltransferase activity, as well as the mammalian DGAT2α polypeptide products encoded thereby and methods for producing the same, are provided. The subject DGAT2α polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications, as well as in treatment therapies and in the production of triacylglycerols.
摘要翻译：提供了编码具有甘油二酯酰基转移酶活性的哺乳动物DGAT2α多肽产物的核酸组合物，以及由此编码的哺乳动物DGAT2α多肽产物及其制备方法。主题DGAT2α多肽和核酸组合物可用于各种应用，包括研究，诊断和治疗剂筛选应用，以及治疗疗法和三酰基甘油的生产。

18. 发明申请

US20100126938A1 PROCESS AND APPARATUS FOR SEPARATING AND RECOVERING WASTE ALKALI FROM CYCLOHEXANE OXIDATION SOLUTION 有权
标题翻译：从环己烷氧化溶液中分离和回收废物碱的工艺和装置
公开(公告)号：US20100126938A1
公开(公告)日：2010-05-27
申请号：US12358004
申请日：2009-01-22
申请人： Zhishan BAI , Zhuoqun Qian , Ji Ma , Ping Zhou , Yanhong Zhang , Hualin Wang
发明人： Zhishan BAI , Zhuoqun Qian , Ji Ma , Ping Zhou , Yanhong Zhang , Hualin Wang
IPC分类号： B01D21/00
CPC分类号： C07C45/33 , B01D17/0214 , C07C2601/14 , Y10S210/908 , C07C49/403
摘要： The present invention relates to a process and an apparatus for separating and recovering the waste alkali from a cyclohexane oxidation solution, and provides a process and an apparatus for separating and recovering the waste alkali from a cyclohexane oxidation solution. According to the invention, a gradient combination of the gravity separation technique, the vortex separation technique and the coalescence separation technique is used to carry out fine separation of the waste alkali liquor from the cyclohexane oxidation solution. The purified cyclohexane oxidation solution is fed into a down-stream apparatus. Most of the waste alkali liquor thus separated is recycled, while the remaining is expelled. The expelled waste alkali liquor is incinerated in an incinerator, followed by recovering the molten species using a pneumatic pulverization process. According to the invention, the content of Na+ in the cyclohexane oxidation solution fed into the alkane tower can be lowered to less than 3 mg/L, and the molten species resulting from incineration can be recovered 100%. Thus, risk of environmental pollution by the waste alkali liquor is substantially eliminated. While the invention is well suited to separate and recover the waste alkali liquor from a cyclohexane oxidation solution, it may be adapted to other chemical engineering systems for separating and recovering waste alkali liquor as well.
摘要翻译：本发明涉及从环己烷氧化溶液中分离回收废碱的方法和装置，提供了从环己烷氧化溶液中分离回收废碱的方法和装置。根据本发明，使用重力分离技术，涡流分离技术和聚结分离技术的梯度组合来进行废碱液与环己烷氧化溶液的精细分离。将纯化的环己烷氧化溶液进料到下游装置中。大部分如此分离的废碱液体被回收，而其余的被排出。将排出的废碱液在焚化炉中焚烧，然后使用气动粉碎法回收熔融物质。根据本发明，进料到烷烃塔中的环己烷氧化溶液中的Na +含量可以降低到小于3mg / L，焚烧产生的熔融物质可以回收100％。因此，废碱液的环境污染的风险基本上被消除。尽管本发明非常适合于从环己烷氧化溶液中分离和回收废碱液体，但是也可以适用于用于分离和回收废碱液的其它化学工程系统。

19. 发明授权

US07705030B2 Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation 失效
标题翻译：氨基-5-（5元）杂芳基咪唑酮化合物及其用于分泌酶调节的用途
公开(公告)号：US07705030B2
公开(公告)日：2010-04-27
申请号：US12180795
申请日：2008-07-28
申请人： Michael Sotirios Malamas , Ping Zhou , William Floyd Fobare , William Ronald Solvibile , Iwan Suwandi Gunawan , James Joseph Erdei , Yinfa Yan , Patrick Michael Andrae , Dominick Anthony Quagliato
发明人： Michael Sotirios Malamas , Ping Zhou , William Floyd Fobare , William Ronald Solvibile , Iwan Suwandi Gunawan , James Joseph Erdei , Yinfa Yan , Patrick Michael Andrae , Dominick Anthony Quagliato
IPC分类号： A61K31/4178 , A61K31/4439 , A61K31/506 , C07D403/14 , C07D401/14 , C07D233/88
CPC分类号： C07D417/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D417/14
摘要： The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
摘要翻译：本发明提供式I的2-氨基-5-杂芳基-5-苯基咪唑酮化合物本发明还提供了其用于抑制和分泌（BACE）和治疗和淀粉样蛋白沉积物和神经原纤维缠结的方法。

20. 发明授权

US07482349B2 Amino-5,5-diphenylimidazolone derivatives for the inhibition of β-secretase 失效
标题翻译：用于抑制β-分泌酶的氨基-5,5-二苯基咪唑啉酮衍生物
公开(公告)号：US07482349B2
公开(公告)日：2009-01-27
申请号：US11153633
申请日：2005-06-15
申请人： Michael S. Malamas , James J. Erdei , Iwan S. Gunawan , Ping Zhou , Yinfa Yan , Dominic A. Quagliato
发明人： Michael S. Malamas , James J. Erdei , Iwan S. Gunawan , Ping Zhou , Yinfa Yan , Dominic A. Quagliato
IPC分类号： C07D401/10 , C07D403/10 , C07D405/14 , A61K31/4178
CPC分类号： C07D405/14 , C07D401/10 , C07D403/10
摘要： The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.
摘要翻译：本发明提供式I化合物及其用于治疗，预防或改善患者中β-淀粉样蛋白沉积物升高或β-淀粉样蛋白水平升高的疾病或病症的用途。

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