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11. 发明申请

US20080292684A1 Device for Delivery of Active Principles 审中-公开
标题翻译：交付活动原则的设备
公开(公告)号：US20080292684A1
公开(公告)日：2008-11-27
申请号：US11658282
申请日：2005-07-22
申请人： Paolo Colombo , Patrizia Santi , Sara Nicoli , Cristina Padula , Fabio Marra
发明人： Paolo Colombo , Patrizia Santi , Sara Nicoli , Cristina Padula , Fabio Marra
IPC分类号： A61F13/00
CPC分类号： A61K9/7053 , A61K9/7061
摘要： A device for the delivery of active principles for dermal and, in particular, transdermal application having the form of a two-layered patch consisting of a first layer having a homogeneous composition and comprising at least one active principle, a water-soluble film-forming agent and a hydrophilic adhesive polymer, and of a second layer joined in a permanent manner to the first and having a water vapour permeability of less than 500 g/m2 in 24 hours.
摘要翻译：用于递送用于皮肤的活性成分的装置，特别是经皮施用，其具有由具有均匀组成并包含至少一种活性成分的第一层组成的双层贴剂形式，水溶性成膜剂试剂和亲水性粘合剂聚合物，以及在永久性方式连接到第一层并在24小时内具有小于500g / m 2的水蒸气渗透性的第二层。

12. 发明授权

US09638152B2 Electric heater, heating device and heating system 有权
公开(公告)号：US09638152B2
公开(公告)日：2017-05-02
申请号：US13508092
申请日：2010-11-02
申请人： Mauro Zorzetto , Alberto Barbano , Paolo Colombo , Mirco Arata
发明人： Mauro Zorzetto , Alberto Barbano , Paolo Colombo , Mirco Arata
IPC分类号： F24H1/10 , H05B3/08 , F02B3/00 , F02M53/02 , F02M53/06
CPC分类号： F02M53/02 , F02M53/06
摘要： An electric heater for fuel of endothermal engines, in particular for fuel systems called “common rail” and the like, includes a heating part and a terminal adapted to be associated with one end of the hollow body of a fuel feeding duct; advantageously, the terminal is at least partly made of plastic material. A fuel feeding duct to which the heater is applied, as well as to a fuel warm-up device, are also provided.

13. 发明授权

US09109938B2 Level sensor and associated control circuit, in particular for a filter for vehicles 有权
标题翻译：液位传感器和相关的控制电路，特别是用于车辆的过滤器
公开(公告)号：US09109938B2
公开(公告)日：2015-08-18
申请号：US13322411
申请日：2010-05-25
申请人： Marco Molinaro , Mauro Zorzetto , Paolo Colombo
发明人： Marco Molinaro , Mauro Zorzetto , Paolo Colombo
IPC分类号： G01F23/24
CPC分类号： G01F23/244 , G01F23/242
摘要： A sensing device includes at least one electrode pair (2, 3, 4) and one sensing circuit (140) connected to the electrode pair (2, 3, 4). The sensing circuit (140) switches the value of its own output voltage when a substance establishes contact across the electrodes (2, 3, 4). The device further includes one output circuit (180) connected to the output of the sensing circuit (140) and adapted to provide an output signal (s7) representative of the presence of a substance across the electrode pair (2, 3, 4). The device also allows the output signal to take different voltage and/or current and/or frequency values, in particular such that values can be discerned which are representative of the presence or level of substances and/or representative of faults of the device.
摘要翻译：感测装置包括连接到电极对（2,3,4）的至少一个电极对（2,3,4）和一个感测电路（140）。当物质在电极（2,3,4）之间建立接触时，感测电路（140）切换其自身输出电压的值。该装置还包括连接到感测电路（140）的输出的一个输出电路（180），并且适于提供表示跨过电极对（2,3,4）的物质的存在的输出信号（s7）。该装置还允许输出信号采取不同的电压和/或电流和/或频率值，特别是使得可以识别代表物质的存在或水平和/或代表装置的故障的值。

14. 发明授权

US08988209B2 Device for monitoring a vehicle wheel 有权
标题翻译：用于监控车轮的装置
公开(公告)号：US08988209B2
公开(公告)日：2015-03-24
申请号：US13514844
申请日：2010-12-10
申请人： Domenico Cantarelli , Paolo Colombo
发明人： Domenico Cantarelli , Paolo Colombo
IPC分类号： B60Q1/00 , B60C23/02 , G01L27/00 , G01M17/02 , B60C23/00 , B60C23/04
CPC分类号： B60C23/0408 , B60C23/0452 , B60C23/0494
摘要： A monitoring device (20) of a vehicle wheel (11) is configured for detecting and transmitting, by a wireless connection, information relating to at least one characteristic quantity of the status of the wheel (11), such as the inflating pressure of a tire thereof. The device (20) has a casing (21-22) housing a circuit (30) adapted to transmit said information, the casing (21-22) being designed for coupling to an end portion (3a) of electrically conductive body (3) of a tire valve (2) of the wheel (11). The casing (21-22) includes a casing body (21) integrating interconnection means (28, 29, 40) prearranged to obtain both an electric connection of the circuit (30) to the end portion (3a) of the electrically conductive body (3) of the valve (2; 2′; 2″), and a mechanical coupling of the casing (21-22) to the end portion (3a) of the electrically conductive body (3) of the valve (2; 2′; 2″).
摘要翻译：车轮（11）的监视装置（20）被配置为通过无线连接来检测和发送与轮（11）的状态的至少一个特征量有关的信息，例如，其轮胎。设备（20）具有容纳适于传输所述信息的电路（30）的壳体（21-22），所述壳体（21-22）被设计成耦合到导电体（3）的端部（3a）的轮胎（11）的轮胎气门（2）。壳体（21-22）包括集成互连装置（28,29,40）的壳体（21），该互连装置预先布置成获得电路（30）到导电体的端部（3a）的电连接的阀（2; 2'; 2“）的导电体（3）的端部（3a）的机械联接， ; 2“）。

15. 发明授权

US08505386B2 Pressure sensor device 有权
标题翻译：压力传感器装置
公开(公告)号：US08505386B2
公开(公告)日：2013-08-13
申请号：US13000287
申请日：2009-06-17
申请人： Paolo Colombo , Domenico Cantarelli , Marco Bigliati , Mauro Zorzetto , Fabio Nebbia , Giorgio Martinengo
发明人： Paolo Colombo , Domenico Cantarelli , Marco Bigliati , Mauro Zorzetto , Fabio Nebbia , Giorgio Martinengo
IPC分类号： G01L19/14 , G01L19/04
CPC分类号： G01L19/0084 , G01L19/0038 , G01L19/0092 , G01L19/06 , G01L19/0609 , G01L19/141
摘要： A pressure sensor device comprises a casing (2a, 3 a) defining a chamber (20) and an inlet passage (14a, 14b) of the chamber. Accommodated in the chamber (20) is a pressure sensor (17) having a sensor body with a cavity and a membrane capable of deformation under pressure action of a fluid present in the inlet passage (14a, 14b). The device further comprises a circuit arrangement (26, 27, 30) to which the pressure sensor (17) is electrically connected, the circuit arrangement including a circuit support at least partially accommodated in the chamber (20). The sensor body is not rigidly associated to the casing (2a, 3 a) and/or to other parts of the device (26, 27, 30, 35), i.e. it is mounted elastically or in a moveable manner with respect to the casing (2a, 3 a) and/or to said other parts (26, 27, 30, 35) inside the chamber (20).
摘要翻译：压力传感器装置包括限定腔室（20）和腔室的入口通道（14a，14b）的壳体（2a，3a）。容纳在腔室（20）中的是一个压力传感器（17），该压力传感器（17）具有一个具有空腔的传感器主体和能够在入口通道（14a，14b）中存在的流体的压力作用下变形的膜。该装置还包括一个电路装置（26,27,30），压力传感器（17）被电连接到该电路装置上，电路装置包括至少部分地容纳在腔室（20）中的电路支架。传感器体不与壳体（2a，3a）和/或与装置（26,27,30,35）的其它部分刚性地相关联，即其相对于壳体弹性地或以可移动的方式安装（2a，3a）和/或所述室（20）内的所述其它部分（26,27,30,35）。

16. 发明申请

US20120011937A1 Pressure-sensor device 有权
标题翻译：压力传感器装置
公开(公告)号：US20120011937A1
公开(公告)日：2012-01-19
申请号：US13200323
申请日：2011-09-23
申请人： Marco Bigliati , Paolo Colombo , Giorgio Martinengo , Daniel Verner Mueller , Mauro Zorzetto
发明人： Marco Bigliati , Paolo Colombo , Giorgio Martinengo , Daniel Verner Mueller , Mauro Zorzetto
IPC分类号： G01L7/00
CPC分类号： G01L9/0052 , G01L19/0672 , G01L19/143 , G01L19/147
摘要： A pressure-sensor device (1) comprises: —a pressure-sensitive component (9) having a body, defined in which is a blind cavity, and having a membrane portion (9a), operatively associated to which is a detection element (R); and —a connection structure (2), which has a duct in communication with the cavity of the pressure-sensitive component (9) and is to receive a fluid, a pressure of which is to be detected. The connection structure (2) comprises a supporting body (2a) of the pressure-sensitive component (9), which defines a respective passage (2b), and a compressible element (12, 18) that is designed to be in contact with the fluid and is configured for compensating possible variations of volume thereof. The compressible element (12, 18) is positioned at least in part within the cavity (11) of the pressure-sensitive component (9) and/or in a stretch of the passage (2b) of the supporting body (2a) that is close to the cavity (11) of the pressure-sensitive component (9).
摘要翻译：一种压力传感器装置（1）包括： - 具有主体的压敏部件（9），其限定为盲腔，并且具有膜部分（9a），其可操作地与检测元件（R ）; 和 - 连接结构（2），其具有与压敏部件（9）的空腔连通的管道，并且接收要被检测的压力的流体。连接结构（2）包括限定相应通道（2b）的压敏部件（9）的支撑体（2a）和设计成与所述压力敏感部件（9）接触的可压缩元件（12,18）并且被配置为补偿其体积的可能变化。可压缩元件（12,18）至少部分地位于压敏部件（9）的空腔（11）内和/或定位在支撑体（2a）的通道（2b）靠近压敏部件（9）的空腔（11）。

17. 发明授权

US07625865B2 Insulin highly respirable microparticles 有权
标题翻译：胰岛素高度可呼吸的微粒
公开(公告)号：US07625865B2
公开(公告)日：2009-12-01
申请号：US10593861
申请日：2004-03-26
申请人： Paolo Colombo , Stefano Cagnani , Paolo Ventura
发明人： Paolo Colombo , Stefano Cagnani , Paolo Ventura
IPC分类号： A61K38/28 , A61K51/12
CPC分类号： A61K9/0075 , A61K9/1688 , A61K38/28
摘要： The invention describes novel dried powders of peptide therapeutic agent useful for producing highly respirable aerosols and the methods for their manufacture. Insulin is the peptide therapeutic agent in the preferred embodiment. The powders of insulin prepared for pulmonary administration are characterized by the peculiar structure and shape of the microparticles that allow the powder to flow and to be easy aerosolized. Typical dry powder of insulin described in this patent show corrugated, nonagglomerated microparticles with a low tapped density. The mean geometric diameter (particle size) ranges between 1.0 and 10.0 micron and the mass median aerodynamic diameter (MMAD) ranges between 1.0 and 4.0 micron. These insulin pulmonary powders exhibit in vitro a very high respirable fraction (>75%).
摘要翻译：本发明描述了用于生产高吸入性气溶胶的肽治疗剂的新颖干粉及其制备方法。胰岛素是优选实施方案中的肽治疗剂。制备用于肺部给药的胰岛素粉末的特征在于允许粉末流动并易于雾化的微粒的特殊结构和形状。在该专利中描述的典型的胰岛素干粉末显示具有低抽头密度的波纹状，非团聚微粒。平均几何直径（粒径）在1.0和10.0微米之间，质量中值空气动力学直径（MMAD）在1.0和4.0微米之间。这些胰岛素肺粉末在体外表现出非常高的可呼吸分数（> 75％）。

18. 发明授权

US07116078B2 Protection system of a vehicle battery 有权
标题翻译：汽车电池保护系统
公开(公告)号：US07116078B2
公开(公告)日：2006-10-03
申请号：US10521353
申请日：2003-07-30
申请人： Paolo Colombo , Marco Bigliati
发明人： Paolo Colombo , Marco Bigliati
IPC分类号： H02J7/00
CPC分类号： H02J7/0032
摘要： A system for protecting the battery of a vehicle includes a device (1) for electrically disconnecting of connecting the battery (BA) with respect to an electric load (CS). The device (1) includes a switch (20, 21) and a microprocessor control circuit (15). The control circuit (15) includes a unit for calculating a mean value of the voltage of the battery (BA) and comparing it with a threshold value, in order to control the switch (20, 21). The threshold value is variable as a function of the ambient temperature and the time of inactivity of the motor. The switch includes a bistable electromagnetic arrangement, capable of passing from a first to a second stable condition following a pulse generated by the control circuit (15).
摘要翻译：用于保护车辆的电池的系统包括用于相对于电负载（CS）电连接电池（BA）的装置（1）。装置（1）包括开关（20,21）和微处理器控制电路（15）。控制电路（15）包括用于计算电池（BA）的电压的平均值并将其与阈值进行比较的单元，以便控制开关（20,21）。阈值根据环境温度和电机不活动时间的变化而变化。开关包括双稳态电磁装置，能够在由控制电路（15）产生的脉冲之后从第一稳定状态通过到第二稳定状态。

19. 发明申请

US20050031631A1 Parietaria judaica ns-ltp antigen variants, uses thereof and compositions comprising them 审中-公开
标题翻译： Parietaria judaica ns-ltp抗原变体，其用途和包含它们的组合物
公开(公告)号：US20050031631A1
公开(公告)日：2005-02-10
申请号：US10380002
申请日：2001-09-11
申请人： Domenico Geraci , Paolo Colombo , Giovanni Duro , Vincenzo Izzo , Maria Costa
发明人： Domenico Geraci , Paolo Colombo , Giovanni Duro , Vincenzo Izzo , Maria Costa
IPC分类号： A61K38/095 , C07K14/415 , C12N15/28 , A61K39/00 , C12N9/00
CPC分类号： C07K14/415 , A61K38/00
摘要： The present invention relates to hypoallergenic variants of ns-LTPs allergens, to pharmaceutical compositions comprising them and to the use of such variants for the preparation of medicaments suitable in the treatment and in the prevention of the allergic forms associated with an ns-LTP allergen, in particular to the allergen corresponding to the variant used.
摘要翻译：本发明涉及ns-LTPs变应原的低变应原变体，包含它们的药物组合物以及这些变体用于制备适合于治疗和预防与ns-LTP变应原相关的过敏形式的药物的用途，特别是对应于所用变体的变应原。

20. 发明授权

US4568580A Laminated packaging films and related articles of manufacture having improved resistance to heat treatment 失效
标题翻译：具有改进的耐热处理性能的层压包装膜和相关制品
公开(公告)号：US4568580A
公开(公告)日：1986-02-04
申请号：US533190
申请日：1983-09-19
申请人： Ezio Ghirardello , Cesare Quacquarella , Paolo Colombo , Francesco Pezzana
发明人： Ezio Ghirardello , Cesare Quacquarella , Paolo Colombo , Francesco Pezzana
IPC分类号： B32B7/02 , B32B7/10 , B32B27/08 , B32B27/28 , B32B27/30 , B32B27/32 , B32B27/34 , B65D65/40 , B27N5/02
CPC分类号： B32B27/08 , B29K2027/08 , Y10T428/1328 , Y10T428/1331 , Y10T428/1334 , Y10T428/1341 , Y10T428/1345 , Y10T428/31732 , Y10T428/31743 , Y10T428/3175
摘要： The invention relates to laminated films and articles of manufacture based on such films and having improved resistance to heat treatment, wherein said films comprise a heat sealing layer of copolyamide obtained by random copolymerization of precursor monomers of at least two different polyamides. Said laminated films, or the articles of manufacture formed therefrom, such as bags or preformed containers, are useful for packaging applications, particularly in connection with food products.
摘要翻译：本发明涉及基于这种膜并且具有改进的耐热处理性能的层压薄膜和制品，其中所述薄膜包括通过至少两种不同聚酰胺的前体单体的无规共聚得到的共聚酰胺的热封层。所述层压膜或由其形成的制品例如袋或预制容器可用于包装应用，特别是与食品有关的应用。

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