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11. 发明申请

US20070106199A1 Implantable pump apparatuses 失效
标题翻译：可植入泵装置
公开(公告)号：US20070106199A1
公开(公告)日：2007-05-10
申请号：US11261739
申请日：2005-10-31
申请人： Daniel Krivoy , Mohsen Shahinpoor , David Soltanpour
发明人： Daniel Krivoy , Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61M5/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61M1/0023 , A61M5/14276 , A61M5/14586 , A61M5/14593 , A61M2205/0244 , A61M2205/0283 , A61M2210/0612 , F04B43/04 , F04B43/043
摘要： An implantable, miniature pump assembly having a flexible elastic bladder actuating assembly. The bladder, in the non-flexed state, has an elongated, substantially rectangular profile, with a predetermined internal volume or capacity. Influent and effluent conduits extend in opposite directions from respective end portions of the bladder. Each of the conduits include one way valves disposed therein to limit fluid flow to a single direction into and through the bladder. Contraction and expansion of the bladder by means of energy harvested from the dynamic environment in which it is implanted in response to ambient random dynamic motion creates alternating pressure and vacuum within the bladder, alternately drawing fluid into the bladder through the influent conduit, and forcing fluid from the bladder via the effluent conduit. The bladder pump assembly harvests its operational energy from the random dynamic motion of the surrounding organs and tissues and therefore does not require an internal or external power source.
摘要翻译：一种可植入的微型泵组件，其具有柔性弹性囊致动组件。处于非弯曲状态的囊状物具有细长的基本矩形的轮廓，具有预定的内部体积或容量。入口和流出物导管从膀胱的相应端部沿相反方向延伸。每个导管包括设置在其中的单向阀以限制流体流向单个方向进入和穿过囊。通过从动态环境中收集的能量来收集膀胱，通过其环境随机动态运动而植入膀胱，在膀胱内产生交替的压力和真空，交替地通过流体导管将液体吸入膀胱，迫使流体从膀胱经由流出物导管。膀胱泵组件从周围器官和组织的随机动态运动中获得其操作能量，因此不需要内部或外部电源。

12. 发明授权

US07060094B2 Accommodating zonular mini-bridge implants 失效
公开(公告)号：US07060094B2
公开(公告)日：2006-06-13
申请号：US09759766
申请日：2001-01-12
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/14
CPC分类号： A61F9/0017 , A61F2/08 , A61F2/14 , A61F9/007 , A61F2210/0014
摘要： Surgical correction of presbyopia and hyperopia by a circularly distributed assembly of mini-bridges implanted between the interior surfaces of the ciliary muscle and the exterior surface of the lens capsule, for augmenting the transmission of the contraction force of the ciliary muscle/zonule assembly to the lens capsule. The lens is symmetrically squeezed by mini-bridges acting in concert with the ciliary muscle thus changing the curvature of the lens. The mini-bridges are composite synthetic muscles comprising either passive biocompatible mini-bridges made with polymeric gels, silicone polymers or a composite, electromagnetically or mechanically deployable mini-bridges, inflatable balloons or synthetic muscles. The surgical procedure comprises using a ciliary muscle relaxant to stretch the lens/zonules/ciliary muscle assembly. An ultrasonic biomicroscope (UBM) is then used to enable the surgeon to see the area for implantation and the mini-bridges and thus perform endoscopic or incisional surgery to implant the mini-bridges in and around zonular cavities.

13. 发明授权

US08454691B2 Surgical correction of ptosis by polymeric artificial muscles 有权
公开(公告)号：US08454691B2
公开(公告)日：2013-06-04
申请号：US12605374
申请日：2009-10-26
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/14 , A61F2/08 , A61F2/00
CPC分类号： A61F2/08 , A61F2002/0894
摘要： A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise an eyelid. The surgical procedure includes implantation and suturing of eye drop (pH) activated and actuated fibrous contractile and expansive artificial muscles such as pH active hydrogels of polyacrylonitrile (PAN) artificial muscles that are surgically implanted and sutured under the superior palpebral conjunctiva in a serpentine parallel configuration with respect to the tarsal (meibomian) glands of the upper eyelid and anchored to the tissues of superior fornix.

14. 发明申请

US20100042146A1 SURGICAL CORRECTION OF PTOSIS BY POLYMERIC ARTIFICIAL MUSCLES 有权
标题翻译：通过聚合物人造血管对组织的外科矫正
公开(公告)号：US20100042146A1
公开(公告)日：2010-02-18
申请号：US12605374
申请日：2009-10-26
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/08 , A61B17/06
CPC分类号： A61F2/08 , A61F2002/0894
摘要： A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise an eyelid. The surgical procedure includes implantation and suturing of eye drop (pH) activated and actuated fibrous contractile and expansive artificial muscles such as pH active hydrogels of polyacrylonitrile (PAN) artificial muscles that are surgically implanted and sutured under the superior palpebral conjunctiva in a serpentine parallel configuration with respect to the tarsal (meibomian) glands of the upper eyelid and anchored to the tissues of superior fornix.
摘要翻译：描述了用于恢复患有上睑下垂或上眼睑下垂综合征的个体中的眼睑功能的外科手术，其使患者不能自愿完全抬起眼睑。外科手术包括植入和缝合眼药水（pH）激活和致动的纤维收缩和膨胀人造肌肉，例如聚丙烯腈（PAN）人造肌肉的pH活性水凝胶，其以蜿蜒平行配置手术植入和缝合在上睑结膜下相对于上眼睑的睑板腺（睑板腺）腺，并锚固于上穹窿的组织。

15. 发明申请

US20070196430A1 Synthetic muscle-based multi-powered active contact lens 失效
标题翻译：合成肌肉多动力隐形眼镜
公开(公告)号：US20070196430A1
公开(公告)日：2007-08-23
申请号：US11358530
申请日：2006-02-21
申请人： Mohsen Shahinpoor , David Soltanpour
发明人： Mohsen Shahinpoor , David Soltanpour
IPC分类号： A61F2/02
CPC分类号： G02C7/04 , G02B1/043
摘要： A novel active contact lens system configured to allow the wearer to alter the corrective features of the contact lens by means of a biasing force. The biasing force can, for example, be different eye drop solutions having different pH levels.
摘要翻译：一种新颖的主动隐形眼镜系统，其被配置为允许穿戴者借助于偏压力改变隐形眼镜的矫正特征。例如，偏置力可以是具有不同pH水平的不同的滴眼液。

16. 发明授权

US06589198B1 Implantable micro-pump assembly 失效
标题翻译：植入式微型泵组件
公开(公告)号：US06589198B1
公开(公告)日：2003-07-08
申请号：US09586962
申请日：2000-06-05
申请人： David Soltanpour , Mohsen Shahinpoor
发明人： David Soltanpour , Mohsen Shahinpoor
IPC分类号： A61M500
CPC分类号： A61M5/14586 , A61F9/00781 , A61M1/0023 , A61M5/14276 , A61M5/14593 , F04B43/04 , F04B43/043 , Y10S977/868 , Y10S977/906
摘要： Self-powered, bio- implantable, pressure adjustable mini-pump systems for medical applications including body fluid pressure control, drainage control, and drug delivery systems. The mini-pump systems include a primary mini-pump chamber having an anterior end attached to an implantable intake conduit. The device of the invention is further equipped with an adjustable variable flow valve or shunt in the form of a first cantilever slab, in combination with an anterior end one-way valve in the form of another cantilever slab. The posterior end of the mini-pump chamber is connected to a drainage conduit, via another one-way valve. Opposing diaphragm elements in the form of a pair of oscillatory flexing miniature ionic polymer metal composite IPPC artificial muscles, is used to vary the volume of the primary mini-pump chamber and thereby effect pumping action. A key feature of the invention is a secondary power generation system, which, in one embodiment of the invention comprises a relatively large piece of IPPC artificial muscle which, for certain types of implants, may be attached to local muscle tissue. Contraction and expansion of the local muscle tissue causes flexure of the IPPC artificial muscle, thereby generating a voltage for driving the diaphragm elements.
摘要翻译：用于医疗应用的自供电，生物可植入，压力可调微型泵系统，包括体液压力控制，排水控制和药物输送系统。微型泵系统包括具有连接到可植入进气管道的前端的初级小型泵室。本发明的装置还配备有可调节的可变流量阀或以第一悬臂板的形式分流，与另一悬臂板形式的前端单向阀组合。小型泵室的后端通过另一个单向阀连接到排水管道。以一对摆动弯曲微型离子聚合物金属复合IPPC人造肌的形式的相反的隔膜元件用于改变初级微型泵室的体积，从而实现泵送作用。本发明的一个关键特征是二次发电系统，其在本发明的一个实施例中包括相对较大的IPPC人造肌肉片，对于某些类型的植入物，可以将其连接到局部肌肉组织。局部肌肉组织的收缩和扩张导致IPPC人造肌肉的弯曲，由此产生用于驱动隔膜元件的电压。

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