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11. 发明申请

US20100327494A1 Electrospun Fibrous Three-Dimensional Scaffolds with Well-Defined Pore Geometry 审中-公开
标题翻译：具有良好定义孔径几何的电纺纤维三维支架
公开(公告)号：US20100327494A1
公开(公告)日：2010-12-30
申请号：US12820691
申请日：2010-06-22
申请人： Esmaiel Jabbari
发明人： Esmaiel Jabbari
IPC分类号： B29C47/36
CPC分类号： D01D5/0076 , B29C48/02 , B29C48/475 , D01D7/00 , D04H3/005 , D04H3/011 , D04H3/04
摘要： In accordance with certain embodiments of the present disclosure, a method for fabricating multi-layer fibrous scaffolds with a well-defined pore geometry is provided. The method includes electrospinning generally parallel rows of biodegradable synthetic polymer fibers onto a collector plate, wherein the fibers of each generally parallel row on the collector plate are generally aligned as they are electrospun onto the collector plate. The collector plate is rotated and additional generally parallel rows of biodegradable synthetic polymer fibers are electrospun onto the collector plate, wherein the additional fibers on the collector plate are generally aligned as they are electrospun onto the collector plate and a multi-layer scaffold is formed. The process can be continued to form a multi-layer fibrous scaffold with macropores of well-defined geometry.
摘要翻译：根据本公开的某些实施方案，提供了一种用于制备具有良好限定的孔几何形状的多层纤维支架的方法。该方法包括将大致平行的可生物降解的合成聚合物纤维的行静电纺丝到集电板上，其中集电板上的每个大致平行的排的纤维通常对齐，因为它们电纺丝到收集板上。收集器板旋转并且附加的大致平行的可生物降解的合成聚合物纤维的行电静电到集电板上，其中集电板上的附加纤维在它们电纺丝到收集板上时通常对准，并且形成多层支架。该方法可以继续形成具有明确几何形状的大孔的多层纤维支架。

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