专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08071363B2 Chip for cell electrophysiological sensor, cell electrophysiological sensor using the same, and manufacturing method of chip for cell electrophysiological sensor 有权
标题翻译：用于细胞电生理传感器的芯片，使用其的细胞电生理传感器，以及用于细胞电生理传感器的芯片的制造方法
公开(公告)号：US08071363B2
公开(公告)日：2011-12-06
申请号：US11914283
申请日：2007-05-21
申请人： Soichiro Hiraoka , Masaya Nakatani , Hiroshi Ushio , Akiyoshi Oshima
发明人： Soichiro Hiraoka , Masaya Nakatani , Hiroshi Ushio , Akiyoshi Oshima
IPC分类号： C12M1/34
CPC分类号： G01N33/48728
摘要： A chip for a cell electrophysiological sensor has a substrate. The substrate has a through-hole formed from the upside to the downside, and the opening of the through-hole is formed in a curved surface curved from the upside and downside of the substrate toward the inner side of the through-hole. In this configuration, the electrolyte solution (first electrolyte solution and second electrolyte solution) flows more smoothly, and the sample cell can be sucked accurately, and the trapping rate of the sample cells is improved.
摘要翻译：用于细胞电生理学传感器的芯片具有基底。基板具有从上侧到下侧形成的通孔，并且通孔的开口形成为从基板的上侧和下侧朝向通孔的内侧弯曲的弯曲表面。在这种结构中，电解质溶液（第一电解质溶液和第二电解质溶液）流畅地流动，可以精确地吸取样品池，提高了样品池的捕获率。

12. 发明申请

US20100126922A1 COMPONENT SEPARATION DEVICE 有权
标题翻译：组件分离装置
公开(公告)号：US20100126922A1
公开(公告)日：2010-05-27
申请号：US12532908
申请日：2008-05-14
申请人： Makoto Takahashi , Masaya Nakatani , Soichiro Hiraoka , Hiroshi Ushio , Akiyoshi Oshima
发明人： Makoto Takahashi , Masaya Nakatani , Soichiro Hiraoka , Hiroshi Ushio , Akiyoshi Oshima
IPC分类号： B01D21/28
CPC分类号： B01D21/283 , B01L3/502753 , B01L3/502761 , B01L2200/0636 , B01L2200/0652 , B01L2300/0816 , B01L2400/0436
摘要： A component separating device includes a flow channel, an acoustic wave generator for generating an acoustic wave in the flow channel, a first inlet channel for introducing a fist solution containing solid particles into the flow channel, a second inlet channel for introducing a second solution, and outlet channels for discharging a solution from the flow channel. A density grade generator is provided at the first inlet channel for forming a density grade of the solid particles. This component separating device extracts the solid particles into a high-purity solution at a high collecting rate.
摘要翻译：元件分离装置包括流路，用于在流路中产生声波的声波发生器，用于将含有固体粒子的第一溶液引入流路的第一入口通道，用于引入第二溶液的第二入口通道，以及用于从流动通道排出溶液的出口通道。在第一入口通道处设置密度级发生器，用于形成固体颗粒的密度等级。该组分分离装置以高收集速率将固体颗粒提取成高纯度溶液。

13. 发明申请

US20100019756A1 DEVICE FOR MEASURING CELLULAR POTENTIAL, SUBSTRATE USED FOR THE SAME AND METHOD OF MANUFACTURING SUBSTRATE FOR DEVICE FOR MEASURING CELLULAR POTENTIAL 审中-公开
标题翻译：用于测量细胞电位的装置，用于其的底物和制造用于测量细胞潜能的装置的基板的方法
公开(公告)号：US20100019756A1
公开(公告)日：2010-01-28
申请号：US11913116
申请日：2007-05-11
申请人： Soichiro Hiraoka , Masaya Nakatani , Hiroshi Ushio
发明人： Soichiro Hiraoka , Masaya Nakatani , Hiroshi Ushio
IPC分类号： G01N27/00 , B32B3/10 , H01B13/00
CPC分类号： G01N33/5438 , G01N33/48728 , G01N33/5005 , Y10T428/24273 , Y10T428/24298
摘要： A device for measuring cellular potential includes a substrate, a first electrode tank, a first electrode, a second electrode tank and a second electrode. The first electrode tank and the second electrode tank are disposed on the upper side and lower side of the substrate, respectively. The first electrode is disposed inside the first electrode tank and the second electrode is disposed inside the second electrode tank. The substrate includes a single crystal plate having a diamond structure with (100) plane orientation or (110) plane orientation. The substrate has a first surface provided with a depression and a second surface facing this first surface. From the depression to the second surface, a through-hole is formed. The depression has an inner wall extending from the opening of the through-hole to the outer periphery, curving and being connected to the first surface.
摘要翻译：用于测量细胞电位的装置包括基板，第一电极槽，第一电极，第二电极槽和第二电极。第一电极槽和第二电极槽分别设置在基板的上侧和下侧。第一电极设置在第一电极槽内，第二电极设置在第二电极槽的内部。衬底包括具有（100）面取向或（110）面取向的金刚石结构的单晶板。衬底具有设置有凹部的第一表面和面向该第一表面的第二表面。从凹陷到第二表面，形成通孔。凹陷具有从通孔的开口延伸到外周的内壁，弯曲并连接到第一表面。

14. 发明授权

US07927474B2 Cell electrophysiological sensor 有权
标题翻译：细胞电生理传感器
公开(公告)号：US07927474B2
公开(公告)日：2011-04-19
申请号：US12828532
申请日：2010-07-01
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
IPC分类号： C12M1/00 , C12M1/34 , C12Q1/00 , G01N27/00
CPC分类号： G01N33/48728
摘要： A cell electrophysiological sensor is provided with: a well having a wall formed by at least one curved face, with opening sections being formed on the two ends thereof; a frame substrate having a through hole and an electrode; a cell electrophysiological sensor chip that is provided with a thin plate having a second through hole; and a void substrate, and in this structure, the frame substrate has a thickness greater than the thickness of the cell electrophysiological sensor chip and the opening diameter of the third opening section is made larger than the opening diameter of the fourth opening section.
摘要翻译：细胞电生理传感器设置有：具有由至少一个曲面形成的壁的孔，其两端形成开口部分; 具有通孔和电极的框架基板; 细胞电生理传感器芯片，其具有具有第二通孔的薄板; 和空隙基板，在该结构中，框架基板的厚度大于单元电生理传感器芯片的厚度，并且第三开口部分的开口直径大于第四开口部分的开口直径。

15. 发明授权

US07776193B2 Cell electrophysiological sensor 有权
标题翻译：细胞电生理传感器
公开(公告)号：US07776193B2
公开(公告)日：2010-08-17
申请号：US11719610
申请日：2006-12-19
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
IPC分类号： C12M1/00 , C12M1/34 , C12Q1/00 , G01N27/00
CPC分类号： G01N33/48728
摘要： A cell electrophysiological sensor is provided with: a well having a wall formed by at least one curved face, with opening sections being formed on the two ends thereof; a frame substrate having a through hole and an electrode; a cell electrophysiological sensor chip that is provided with a thin plate having a second through hole; and a void substrate, and in this structure, the frame substrate has a thickness greater than the thickness of the cell electrophysiological sensor chip and the opening diameter of the third opening section is made larger than the opening diameter of the fourth opening section.
摘要翻译：细胞电生理传感器设置有：具有由至少一个曲面形成的壁的孔，其两端形成开口部分; 具有通孔和电极的框架基板; 细胞电生理传感器芯片，其具有具有第二通孔的薄板; 和空隙基板，在该结构中，框架基板的厚度大于单元电生理传感器芯片的厚度，并且第三开口部分的开口直径大于第四开口部分的开口直径。

16. 发明申请

US20090178922A1 CELL ELECTROPHYSIOLOGICAL SENSOR 有权
标题翻译：细胞电生理传感器
公开(公告)号：US20090178922A1
公开(公告)日：2009-07-16
申请号：US11719610
申请日：2006-12-19
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka
IPC分类号： G01N33/48
CPC分类号： G01N33/48728
摘要： A cell electrophysiological sensor is provided with: a well having a wall formed by at least one curved face, with opening sections being formed on the two ends thereof; a frame substrate having a through hole and an electrode; a cell electrophysiological sensor chip that is provided with a thin plate having a second through hole; and a void substrate, and in this structure, the frame substrate has a thickness greater than the thickness of the cell electrophysiological sensor chip and the opening diameter of the third opening section is made larger than the opening diameter of the fourth opening section.
摘要翻译：细胞电生理传感器设置有：具有由至少一个曲面形成的壁的孔，其两端形成开口部分; 具有通孔和电极的框架基板; 细胞电生理传感器芯片，其具有具有第二通孔的薄板; 和空隙基板，在该结构中，框架基板的厚度大于单元电生理传感器芯片的厚度，并且第三开口部分的开口直径大于第四开口部分的开口直径。

17. 发明申请

US20070108478A1 Cell electro-physiological sensor and method of manufacturing the same 有权
标题翻译：细胞电生理传感器及其制造方法
公开(公告)号：US20070108478A1
公开(公告)日：2007-05-17
申请号：US11272892
申请日：2005-11-14
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
IPC分类号： H01L23/58
CPC分类号： G01N33/48728
摘要： A cell electro-physiological sensor includes a sensor chip including a partition board having a first surface and a second surface opposite to the first surface, a member for forming a first region provided on the first surface of the partition board, and a member for forming a second region provided on the second surface of the partition board. The partition board has a through-hole provided therein, the through-hole having a first opening which opens to the first surface, a second opening which opens to the second surface, and a wall. The first region contacts the first opening of the through-hole. The first region is arranged to contain cell suspension. The atomic ratio of carbon at the first surface of the partition board is not greater than 15 atomic percent of the composition of the first surface. The cell electro-physiological sensor causes the cell to be tightly held at the first opening of the through-hole in the partition board, thereby measuring a potential of the cell efficiently.
摘要翻译：细胞电生理传感器包括传感器芯片，其包括具有第一表面和与第一表面相对的第二表面的隔板，用于形成设置在隔板的第一表面上的第一区域的构件和用于形成设置在隔板的第二表面上的第二区域。分隔板具有设置在其中的通孔，该通孔具有通向第一表面的第一开口，通向第二表面的第二开口和壁。第一区域接触通孔的第一开口。第一个区域被设置成包含细胞悬浮液。分隔板的第一表面处的碳的原子比不大于第一表面的组成的15原子％。细胞电生理传感器使细胞紧密地保持在隔板的通孔的第一开口处，从而有效地测量细胞的电位。

18. 发明授权

US07608417B2 Cell electro-physiological sensor and method of manufacturing the same 有权
标题翻译：细胞电生理传感器及其制造方法
公开(公告)号：US07608417B2
公开(公告)日：2009-10-27
申请号：US11272892
申请日：2005-11-14
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
IPC分类号： C12Q1/02
CPC分类号： G01N33/48728
摘要： A cell electro-physiological sensor includes a sensor chip including a partition board having a first surface and a second surface opposite to the first surface, a member for forming a first region provided on the first surface of the partition board, and a member for forming a second region provided on the second surface of the partition board. The partition board has a through-hole provided therein, the through-hole having a first opening which opens to the first surface, a second opening which opens to the second surface, and a wall. The first region contacts the first opening of the through-hole. The first region is arranged to contain cell suspension. The atomic ratio of carbon at the first surface of the partition board is not greater than 15 atomic percent of the composition of the first surface. The cell electro-physiological sensor causes the cell to be tightly held at the first opening of the through-hole in the partition board, thereby measuring a potential of the cell efficiently.
摘要翻译：细胞电生理传感器包括传感器芯片，其包括具有第一表面和与第一表面相对的第二表面的隔板，用于形成设置在隔板的第一表面上的第一区域的构件和用于形成设置在隔板的第二表面上的第二区域。分隔板具有设置在其中的通孔，该通孔具有通向第一表面的第一开口，通向第二表面的第二开口和壁。第一区域接触通孔的第一开口。第一个区域被设置成包含细胞悬浮液。分隔板的第一表面处的碳的原子比不大于第一表面的组成的15原子％。细胞电生理传感器使细胞紧密地保持在隔板的通孔的第一开口处，从而有效地测量细胞的电位。

19. 发明授权

US08375745B2 Process for producing cell electrophysiological sensor and apparatus for producing the cell electrophysiological sensor 有权
标题翻译：用于生产细胞电生理传感器和用于产生细胞电生理传感器的装置的方法
公开(公告)号：US08375745B2
公开(公告)日：2013-02-19
申请号：US12808499
申请日：2008-11-28
申请人： Hiroshi Ushio , Masaya Nakatani , Makoto Takahashi
发明人： Hiroshi Ushio , Masaya Nakatani , Makoto Takahashi
IPC分类号： C03B23/043 , C03B23/09
CPC分类号： G01N33/48728
摘要： A process including holding sensor chip; holding glass tube surrounding the outer periphery of the side surface of sensor chip; applying a wind pressure to the side surface of glass tube from the outside of glass tube and melting glass tube to be glass-welded to the side surface of sensor chip. Thereby, the outer periphery of sensor chip can be surrounded by a highly hydrophilic glass tube. Thus, a cell electrophysiological sensor with high measurement accuracy can be produced.
摘要翻译：一种包括保持传感器芯片的过程; 围绕传感器芯片侧面外周的玻璃管; 从玻璃管的外侧将玻璃管的侧面施加风压并将玻璃熔融的玻璃管玻璃焊接到传感器芯片的侧面。因此，传感器芯片的外周可以被高度亲水性的玻璃管包围。因此，可以制造具有高测量精度的细胞电生理传感器。

20. 发明授权

US08962248B2 Sequencer 有权
标题翻译：音序器
公开(公告)号：US08962248B2
公开(公告)日：2015-02-24
申请号：US13002691
申请日：2009-06-26
申请人： Masaya Nakatani , Makoto Takahashi , Hiroshi Ushio , Daniel Yazbeck
发明人： Masaya Nakatani , Makoto Takahashi , Hiroshi Ushio , Daniel Yazbeck
IPC分类号： C12Q1/68 , B01J19/00
CPC分类号： C12Q1/6876 , B01J19/0046 , B01J2219/00432 , B01J2219/00509 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00635 , B01J2219/00637 , B01J2219/00644 , B01J2219/00659 , B01J2219/00722 , C12Q1/6825 , C12Q1/6837 , C12Q1/6874 , C12Q2565/507
摘要： A sequencer that measures a nucleic acid sequence in a nucleic acid strand includes: a base material having a surface made of silicon, and a fibrous protrusion that is made of silicon dioxide and is directly joined to the surface of the base material made of silicon, wherein a plurality of the nucleic acid strands are fixed onto the fibrous protrusion.
摘要翻译：测量核酸链中的核酸序列的测序仪包括：具有由硅制成的表面的基材和由二氧化硅制成并直接接合到由硅制成的基材的表面的纤维状突起，其中多个核酸丝束固定在纤维突起上。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式