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11. 发明授权

US07202246B2 Spiro-rifamycin derivatives targeting RNA polymerase 有权
标题翻译：螺 - 利福霉素衍生物靶向RNA聚合酶
公开(公告)号：US07202246B2
公开(公告)日：2007-04-10
申请号：US11147520
申请日：2005-06-08
申请人： Zhenkun Ma , In Ho Kim , Jing Li
发明人： Zhenkun Ma , In Ho Kim , Jing Li
IPC分类号： C07D225/04 , A61K31/495 , A61P31/04
CPC分类号： C07D491/22
摘要： Compounds of the current invention relate to rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms. More specifically, compounds of the current invention relate to a series of novel spiro rifamycin derivatives which have demonstrated potent antimicrobial activity.
摘要翻译：本发明的化合物涉及具有抗微生物活性的利福霉素衍生物，包括抗耐药微生物的活性。更具体地，本发明的化合物涉及一系列已经证明有效的抗微生物活性的新型螺利福霉素衍生物。

12. 发明申请

US20100271485A1 IMAGE PHOTOGRAPHING APPARATUS AND METHOD OF CONTROLLING THE SAME 有权
标题翻译：图像摄影装置及其控制方法
公开(公告)号：US20100271485A1
公开(公告)日：2010-10-28
申请号：US12760697
申请日：2010-04-15
申请人： In Ho Kim
发明人： In Ho Kim
IPC分类号： H04N5/225
CPC分类号： H04N5/232 , G06K9/32 , H04N5/23245 , H04N5/23254
摘要： A method of controlling an image photographing apparatus to track a subject using a non-viewable pixel region of an image sensor includes detecting a motion vector of a subject when a moving image is photographed, determining whether a non-viewable pixel region of an image sensor is present in the direction of the detected motion vector of the subject, and moving a photographing region to the non-viewable pixel region so as to track the motion of the subject. Accordingly, the moving subject may be tracked within a range of a predetermined Field of View (FOV) of the image photographing apparatus without an additional hardware system.
摘要翻译：使用图像传感器的不可见像素区域来控制图像拍摄设备跟踪对象的方法包括：当拍摄运动图像时检测被摄体的运动矢量，确定图像传感器的不可见像素区域存在于检测到的对象的运动矢量的方向上，并且将拍摄区域移动到不可见像素区域，以便跟踪被摄体的运动。因此，可以在没有附加硬件系统的图像拍摄装置的预定视场（FOV）的范围内跟踪移动的被摄体。

13. 发明授权

US07238694B2 Rifamycin imino derivatives effective against drug-resistant microbes 有权
标题翻译：对抗耐药性微生物有效的利福霉素亚氨基衍生物
公开(公告)号：US07238694B2
公开(公告)日：2007-07-03
申请号：US11034279
申请日：2005-01-12
申请人： Charles Z. Ding , Yafei Jin , Jamie C. Longgood , Zhenkun Ma , Jing Li , In Ho Kim , Keith P. Minor , Susan Harran
发明人： Charles Z. Ding , Yafei Jin , Jamie C. Longgood , Zhenkun Ma , Jing Li , In Ho Kim , Keith P. Minor , Susan Harran
IPC分类号： C07D498/08 , C07D519/00 , A61K31/4709 , A61K31/496 , A61P31/04
CPC分类号： C07D498/08 , C07D519/00
摘要： The present invention relates to rifamycin 3-iminomethylenyl (—CH═N—) derivatives having antimicrobial activities, including activities against drug-resistant microorganisms. The claimed rifamycin derivative has a rifamycin moiety covalently linked to a linker through an iminomethylenyl (—CH═N—) group at the C-3 carbon of the rifamycin moiety and the linker is, in turn, covalently linked to a quinolone structure or its pharmacophore within the DNA gyrase and topoisomerase IV inhibitor family. The inventive rifamycins are novel and exhibit activity against both rifampin and ciprofloxacin-resistant microorganisms.
摘要翻译：本发明涉及具有抗菌活性的利福霉素3-亚氨基亚甲基（-CH-N-）衍生物，其包括抗药性微生物的活性。所要求的利福霉素衍生物具有通过利莫霉素部分的C-3碳上的亚氨基亚甲基（-CH-N-）基团与连接体共价连接的利福霉素部分，并且连接体又与喹诺酮结构共价连接或其 DNA促旋酶和拓扑异构酶IV抑制剂家族内的药效团。本发明的利福霉素是新颖的，并且表现出抵抗利福平和环丙沙星抗性微生物的活性。

14. 发明授权

US08532191B2 Image photographing apparatus and method of controlling the same 有权
标题翻译：图像摄影装置及其控制方法
公开(公告)号：US08532191B2
公开(公告)日：2013-09-10
申请号：US12760697
申请日：2010-04-15
申请人： In Ho Kim
发明人： In Ho Kim
IPC分类号： H04N7/26 , H04N7/50
CPC分类号： H04N5/232 , G06K9/32 , H04N5/23245 , H04N5/23254
摘要： A method of controlling an image photographing apparatus to track a subject using a non-viewable pixel region of an image sensor includes detecting a motion vector of a subject when a moving image is photographed, determining whether a non-viewable pixel region of an image sensor is present in the direction of the detected motion vector of the subject, and moving a photographing region to the non-viewable pixel region so as to track the motion of the subject. Accordingly, the moving subject may be tracked within a range of a predetermined Field of View (FOV) of the image photographing apparatus without an additional hardware system.
摘要翻译：使用图像传感器的不可见像素区域来控制图像拍摄设备跟踪对象的方法包括：当拍摄运动图像时检测被摄体的运动矢量，确定图像传感器的不可见像素区域存在于检测到的对象的运动矢量的方向上，并且将拍摄区域移动到不可见像素区域，以便跟踪被摄体的运动。因此，可以在没有附加硬件系统的图像拍摄装置的预定视场（FOV）的范围内跟踪移动的被摄体。

15. 发明申请

US20130020948A1 AMBIENT LIGHTING CONTROL METHOD AND AMBIENT LIGHTING CONTROL SYSTEM 审中-公开
标题翻译：环境照明控制方法和环境照明控制系统
公开(公告)号：US20130020948A1
公开(公告)日：2013-01-24
申请号：US13636688
申请日：2011-03-22
申请人： Mi Sook Han , Hyun Chul Hwang , Seok Hwan Choi , In Ho Kim , Mun Sik Kang , Joon Seok Lee , Hyon Soo Shin , Sung Woo Woo , Jae Baek Heo
发明人： Mi Sook Han , Hyun Chul Hwang , Seok Hwan Choi , In Ho Kim , Mun Sik Kang , Joon Seok Lee , Hyon Soo Shin , Sung Woo Woo , Jae Baek Heo
IPC分类号： H05B37/02
CPC分类号： H05B37/0245 , H05B37/0227 , Y02B20/48
摘要： The present disclosure provides a method of controlling a human-friendly illumination. The method includes determining a displayed object, using a control module, based on at least one data sensed by a sensor module; receiving, by the control module, from a scene database scene data corresponding to the displayed object; creating, by the control module, illumination control information based on the scene data and sending the illumination control information to a lamp control unit; and outputting, by the lamp control unit, an illumination control signal corresponding to the illumination control information to a lamp module.
摘要翻译：本公开提供了一种控制人类友好照明的方法。该方法包括：基于由传感器模块感测的至少一个数据，使用控制模块确定所显示的对象; 由所述控制模块从对应于所显示的对象的场景数据库场景数据接收; 通过所述控制模块生成基于所述场景数据的照明控制信息，并将所述照明控制信息发送到灯控制单元; 以及由所述灯控制单元将与所述照明控制信息对应的照明控制信号输出到灯模块。

16. 发明授权

US07884099B2 Quinolone carboxylic acid-substituted rifamycin derivatives 有权
标题翻译：喹诺酮羧酸取代的利福霉素衍生物
公开(公告)号：US07884099B2
公开(公告)日：2011-02-08
申请号：US12269652
申请日：2008-11-12
申请人： Charles Z. Ding , Yafei Jin , Keith Combrink , In Ho Kim
发明人： Charles Z. Ding , Yafei Jin , Keith Combrink , In Ho Kim
IPC分类号： C07D491/20 , C07D498/16 , A61K31/498 , A61K31/5383
CPC分类号： C07D491/20 , C07D498/16
摘要： The compounds include substituted rifamycin derivatives in which a quinolone carboxylic acid pharmacophore is covalently bonded to a benzoxazinorifamycin or a spiropiperidinorifamycin. The rifamycin derivatives are useful as antimicrobial agents and are effective against a number of human and veterinary Gram positive and Gram negative pathogens. The advantage of the inventive compounds is that both the rifamycin and quinolone antibacterial pharmacophores are co-delivered with matched pharmacokinetics to the targeted pathogens of interests. Delivery of multiple antibacterial pharmacophores simultaneously to the targeted pathogens has the maximum chance of achieving synergy and minimizing the development of resistance to the antibiotics given.
摘要翻译：化合物包括取代的利福霉素衍生物，其中喹诺酮羧酸药效团与苯并恶嗪利福霉素或螺哌啶利多霉素共价键合。利福霉素衍生物可用作抗微生物剂，并且对许多人和兽医革兰氏阳性和革兰氏阴性病原体有效。本发明化合物的优点在于利福霉素和喹诺酮类抗菌药代动力剂与匹配的药代动力学共同输送到感兴趣的靶向病原体。同时向目标病原体递送多个抗菌药代动力，最大限度地实现协同作用，并最大限度地减少给予抗生素的耐药性。

17. 发明授权

US07678791B2 Nitroheteroaryl-containing rifamycin derivatives 有权
标题翻译：含氮杂芳基的利福霉素衍生物
公开(公告)号：US07678791B2
公开(公告)日：2010-03-16
申请号：US11827467
申请日：2007-07-12
申请人： Charles Z. Ding , In Ho Kim , Jiancheng Wang , Zhenkun Ma , Yafei Jin , Keith D. Combrink , Genliang Lu , A. Simon Lynch
发明人： Charles Z. Ding , In Ho Kim , Jiancheng Wang , Zhenkun Ma , Yafei Jin , Keith D. Combrink , Genliang Lu , A. Simon Lynch
IPC分类号： C07D498/22 , A61K31/535 , A61P31/00
CPC分类号： C07D498/18 , C07D498/08 , C07D498/22 , C07D519/00
摘要： Substituted rifamycin derivatives in which a nitroimidazole, nitrothiazole or nitrofuran pharmacophore is covalently bonded to a rifamycin, methods of using the rifamycin derivatives, and pharmaceutical compositions containing the rifamycin derivatives are disclosed. Methods of synthesizing these substituted rifamycin derivatives are also disclosed. The rifamycin derivatives possess antibacterial activity, and are effective against a number of human and veterinary pathogens in the treatment of bacterial diseases.
摘要翻译：公开了其中硝基咪唑，硝基噻唑或硝基呋喃药效团与利福霉素共价结合的取代的利福霉素衍生物，使用利福霉素衍生物的方法和含有利福霉素衍生物的药物组合物。还公开了合成这些取代的利福霉素衍生物的方法。利福霉素衍生物具有抗菌活性，并且在治疗细菌性疾病中对许多人和兽医病原体有效。

18. 发明申请

US20080139577A1 Nitroheteroaryl-containing rifamycin derivatives 有权
标题翻译：含氮杂芳基的利福霉素衍生物
公开(公告)号：US20080139577A1
公开(公告)日：2008-06-12
申请号：US11827467
申请日：2007-07-12
申请人： Charles Z. Ding , In Ho Kim , Jiancheng Wang , Zhenkun Ma , Yafei Jin , Keith D. Combrink , Genliang Lu , A. Simon Lynch
发明人： Charles Z. Ding , In Ho Kim , Jiancheng Wang , Zhenkun Ma , Yafei Jin , Keith D. Combrink , Genliang Lu , A. Simon Lynch
IPC分类号： A61K31/497 , A61P31/04 , C07D267/00
CPC分类号： C07D498/18 , C07D498/08 , C07D498/22 , C07D519/00
摘要： Substituted rifamycin derivatives in which a nitroimidazole, nitrothiazole or nitrofuran pharmacophore is covalently bonded to a rifamycin, methods of using the rifamycin derivatives, and pharmaceutical compositions containing the rifamycin derivatives are disclosed. Methods of synthesizing these substituted rifamycin derivatives are also disclosed. The rifamycin derivatives possess antibacterial activity, and are effective against a number of human and veterinary pathogens in the treatment of bacterial diseases.
摘要翻译：公开了其中硝基咪唑，硝基噻唑或硝基呋喃药效团与利福霉素共价结合的取代的利福霉素衍生物，使用利福霉素衍生物的方法和含有利福霉素衍生物的药物组合物。还公开了合成这些取代的利福霉素衍生物的方法。利福霉素衍生物具有抗菌活性，并且在治疗细菌性疾病中对许多人和兽医病原体有效。

19. 发明授权

US07229996B2 Rifamycin derivatives 有权
标题翻译：利福霉素衍生物
公开(公告)号：US07229996B2
公开(公告)日：2007-06-12
申请号：US11186187
申请日：2005-07-21
申请人： Zhenkun Ma , Jing Li , Susan Harran , Yong He , Keith P. Minor , In Ho Kim , Charles Z. Ding , Jamie C. Longgood , Yafei Jin , Keith D. Combrink
发明人： Zhenkun Ma , Jing Li , Susan Harran , Yong He , Keith P. Minor , In Ho Kim , Charles Z. Ding , Jamie C. Longgood , Yafei Jin , Keith D. Combrink
IPC分类号： C07D498/08 , A61K31/4709 , A61P31/04
CPC分类号： C07D401/12 , C07D455/02
摘要： Novel rifamycin derivatives of formula I (both hydroquinone and corresponding quinone (C1-C4) forms): or their salts, hydrates or prodrugs thereof, wherein: a preferred R comprises hydrogen, acetyl; L is a linker, a preferred linker group elements selected from any combination of 1 to 5 groups shown FIG. 1, provided L is not wherein R1 is H, methyl or alkyl. The inventive compounds exhibit valuable antibiotic properties. Formulations having these compounds can be used in the control or prevention of infectious diseases in mammals, both humans and non-humans. In particular, the compounds exhibit a pronounced antibacterial activity, even against multiresistant strains of microbes.
摘要翻译：式I的新型利福霉素衍生物（氢醌和相应的醌（C 1 -C 4））形成）：或其盐，水合物或前药，其中：优选的R 包括氢，乙酰基; L是接头，优选的连接基团元素选自1至5个组的任何组合，如图1所示。 1，其中L不是其中R 1是H，甲基或烷基。本发明化合物显示出有价值的抗生素性质。具有这些化合物的制剂可以用于控制或预防哺乳动物，包括人和非人的感染性疾病。特别地，这些化合物甚至显示出显着的抗菌活性，即使是针对多抗菌菌株的微生物。

20. 发明申请

US20060063357A1 Singulation method used in image sensor packaging process and support for use therein 有权
标题翻译：图像传感器封装过程中使用的分割方法和其中使用的支持
公开(公告)号：US20060063357A1
公开(公告)日：2006-03-23
申请号：US10944197
申请日：2004-09-20
申请人： Jun Young Yang , In Ho Kim
发明人： Jun Young Yang , In Ho Kim
IPC分类号： H01L21/78 , H01L21/50
CPC分类号： H01L27/14618 , H01L27/14625 , H01L2224/45144 , H01L2224/48091 , H01L2924/00014 , H01L2924/00
摘要： A singulation method used in a process for making a plurality of image sensor packages is disclosed. Firstly, a semi-finished product including a plurality of package structures formed on a substrate is placed on a support having a plurality of cavities for receiving the package structures. Then, the semi-finished product is sawed into separate image sensor packages. During the sawing step, the air pressure in the cavities is decreased to create suction within the cavities such that the support abuts against at least a portion of the housing of each package structure with a gap between the transparent component and the support whereby the package structures are positioned precisely and clamped in place with the support during the sawing step.
摘要翻译：公开了一种用于制造多个图像传感器封装的工艺中的分割方法。首先，将包括形成在基板上的多个封装结构的半成品放置在具有用于接收封装结构的多个空腔的支撑件上。然后，半成品被锯成单独的图像传感器包装。在锯切步骤期间，空腔中的空气压力减小以在空腔内产生吸力，使得支撑件抵靠每个包装结构的壳体的至少一部分，在透明部件和支撑件之间具有间隙，由此包装结构在锯切步骤期间精确地定位并且与支撑件夹紧就位。

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