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    • 14. 发明申请
    • Coating for controlled release of a therapeutic agent
    • 用于治疗剂的控制释放的涂层
    • US20050033417A1
    • 2005-02-10
    • US10883328
    • 2004-07-01
    • John BorgesMaritza CarballoPallassana NarayananWilliam ShawChristopher Widenhouse
    • John BorgesMaritza CarballoPallassana NarayananWilliam ShawChristopher Widenhouse
    • A61B17/04A61B17/11A61B17/115A61F2/84A61K9/00A61K31/395A61K31/436A61L27/28A61L27/34A61L27/54A61L31/00A61L31/10A61L31/16A61P9/10A61F2/06
    • A61K9/0024A61K31/395A61L27/34A61L27/54A61L31/10A61L31/16A61L2300/416A61L2300/608A61L2420/08C08L33/10C08L27/16
    • Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
    • 可以涂覆医疗装置,特别是可植入医疗装置,以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物,药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物,药剂或化合物还可以进一步减少生物体对将生物体引入医疗装置的反应。 此外,这些治疗药物,药剂和/或化合物可用于促进愈合,包括血块的形成。 此外,可以修改装置以促进内皮化。 可以使用各种材料和涂覆方法来将药物,试剂或化合物维持在医疗装置上,直到输送和定位。 此外,可以修改用于递送可植入医疗装置的装置,以减少在展开期间损害可植入医疗装置的可能性。 医疗器械包括支架,移植物,吻合装置,血管周围包裹物,缝线和钉。 此外,可以使用各种聚合物组合来控制来自可植入医疗装置的治疗药物,药剂和/或化合物的洗脱速率。
    • 16. 发明授权
    • Door gap finger guard
    • 门间手指卫兵
    • US06434888B1
    • 2002-08-20
    • US09817537
    • 2001-03-26
    • William ShawWayne Carson
    • William ShawWayne Carson
    • E05D1100
    • E06B7/367Y10T16/5358
    • The present door gap finger guard is comprised of an elongated rigid fixed plate connected to an elongated rigid movable plate by a narrow springy strip. The fixed plate, springy strip, and movable plate are coplanar when relaxed. The fixed plate is adapted to be attached to an interior surface of a doorjamb, and the movable plate is adapted to be biased against a door hinged to the door jamb. Both plates are transparent for blending in with the surrounding architecture. The movable plate is biased against the door regardless of the door's position to cover the door gap at all times. The springy strip is significantly narrower than either the movable plate or the fixed plate, so that most of the guard is of a rigid material that cannot be collapsed when pushed upon for preventing fingers from getting into the door gap.
    • 现在的门间隙手指护罩由细长的刚性固定板组成,该固定板通过狭窄的弹性带连接到细长的刚性可移动板。 固定板,弹性带和可动板在放松时是共面的。 固定板适于附接到门框的内表面,并且可移动板适于偏压铰链到门侧柱的门。 两块板都是透明的,与周围的建筑融合。 无论门的位置何时始终覆盖门间隙,可动板偏压门。 弹性条带比可动板或固定板明显窄,使得大多数防护件是刚性材料,当被推动时不能折叠以防止手指进入门间隙。