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11. 发明授权

US4743107A Ophthalmological diagnosis method and apparatus 失效
标题翻译：眼科诊断方法及装置
公开(公告)号：US4743107A
公开(公告)日：1988-05-10
申请号：US016285
申请日：1987-02-19
申请人： Yoshihisa Aizu , Kouji Ogino
发明人： Yoshihisa Aizu , Kouji Ogino
IPC分类号： A61B3/12 , A61B3/10 , A61B5/02 , G01P3/36
CPC分类号： A61B3/12 , A61B3/1225
摘要： An ophthalmological diagnosis method and an apparatus for carrying out the method are disclosed. According to the method a region of the eye, e.g. the fundus, is illuminated with a laser beam of prescribed diameter to produce a laser speckle pattern formed by light scattered by blood cells within the tissue of the eye, movement of the laser speckle pattern is detected as fluctuation in the light intensity of the speckles at an observation point and a speckle signal corresponding to the detected movement is produced, the power spectrum distribution of the speckle signal is obtained, the power spectrum distribution configuration is evaluated from the results of a calculation of the mean frequency thereof and the blood flow state in the tissue is determined from the results of the evaluation. The apparatus for carrying out this method comprises a laser beam source, a laser beam optical system for guiding laser light from the laser beam source, adjusting it to a predetermined beam diameter and causing it to illuminate a region of eye tissue of predetermined area, means for measuring light scattered from the illuminated region of eye tissue and producing a signal corresponding to the result of the measurement, and means for processing the signal from the measuring means.
摘要翻译：公开了一种用于实施该方法的眼科诊断方法和装置。根据该方法，眼睛的区域，例如，眼底用规定直径的激光照射，产生由眼睛组织内的血细胞散射的光形成的激光斑纹图案，激光斑纹图案的运动被检测为斑点光强度的波动产生与检测到的移动相对应的观察点和散斑信号，获得散斑信号的功率谱分布，根据其平均频率和血流状态的计算结果，评价功率谱分布结构根据评价结果确定组织。用于执行该方法的装置包括激光束源，用于引导来自激光束源的激光的激光束光学系统，将其调整到预定的光束直径并使其照射预定区域的眼睛组织的区域，用于测量从眼组织的照射区域散射的光并产生对应于测量结果的信号，以及用于处理来自测量装置的信号的装置。

12. 发明授权

US5307481A Highly reliable online system 失效
标题翻译：高度可靠的在线系统
公开(公告)号：US5307481A
公开(公告)日：1994-04-26
申请号：US660633
申请日：1991-02-25
申请人： Hiroyuki Shimazaki , Masamichi Mizoguchi , Hajime Yamasaki , Kazuaki Ogawa , Shinji Tanaka , Tatsushi Yano , Takatoshi Shimizu , Yukio Kouguchi , Tetsuo Yamashita , Satoshi Murabayashi , Nobuyuki Suzuki , Yoshikuni Watanabe , Koichi Nakagawa , Daisuke Fukagawa , Kouji Ogino
发明人： Hiroyuki Shimazaki , Masamichi Mizoguchi , Hajime Yamasaki , Kazuaki Ogawa , Shinji Tanaka , Tatsushi Yano , Takatoshi Shimizu , Yukio Kouguchi , Tetsuo Yamashita , Satoshi Murabayashi , Nobuyuki Suzuki , Yoshikuni Watanabe , Koichi Nakagawa , Daisuke Fukagawa , Kouji Ogino
IPC分类号： G06F11/00 , G06F11/14 , G06F11/16 , G06F11/20 , G06F15/21
CPC分类号： G06F11/2097 , G06F11/1662 , G06F11/201 , G06F11/2033 , G06F11/2038 , G06F11/2048 , Y10S707/99953 , Y10S707/99955
摘要： A highly reliable online system is disclosed which is provided with a backup computer center (sub-online system) in addition with an original computer center (main online system) in order to improve the reliability of the online system. With respect to the database, the main online system is provided with an original database (main database) while the sub-online system is provided with a backup database (sub-database) which is a duplicate of the main database. The main online system and the sub-online system are connected through a transmission path. Information on an update performed in the main database is transferred to the sub-online system through the transmission path to thereby update the sub-database in a manner similar to the main database. Terminal units are normally connected to the main online system, wherein the main database is updated by transactions inputted from the terminals. When a failure occurs in the main online system, the terminals are changed over to be connected to the sub-online system to allow transaction processing to be continued. Further, there are provided a control system for synchronizing contents between the main database and the sub-database when the original computer center is changed over to the backup computer center, a recovery system for recovering the main database or the sub-database from failures and an integration system for integrating both the main database and the sub-database when they are independently updated due to a failure in the transmission path or the like.
摘要翻译：公开了一种高可靠性的在线系统，其中还提供了备用计算机中心（次在线系统）以及原始计算机中心（主要在线系统），以提高在线系统的可靠性。对于数据库，主要在线系统提供了原始数据库（主数据库），而在线系统配备有与主数据库重复的备份数据库（子数据库）。主要的在线系统和子在线系统通过传输路径连接。在主数据库中执行的更新的信息通过传输路径被传送到子在线系统，从而以类似于主数据库的方式更新子数据库。终端单元通常连接到主要在线系统，其中通过从终端输入的交易更新主数据库。当主要在线系统出现故障时，终端被切换为连接到在线系统，以允许继续进行事务处理。此外，提供了一种用于当原始计算机中心被切换到备用计算机中心时在主数据库和子数据库之间同步内容的控制系统，用于从故障中恢复主数据库或子数据库的恢复系统，以及一种用于在主数据库和子数据库由于传输路径等故障而独立更新时集成的集成系统。

13. 发明授权

US5090416A Ophthalmological diagnosis method and apparatus 失效
标题翻译：眼科诊断方法与装置
公开(公告)号：US5090416A
公开(公告)日：1992-02-25
申请号：US364488
申请日：1989-06-09
申请人： Kouji Ogino , Yoshihisa Aizu
发明人： Kouji Ogino , Yoshihisa Aizu
IPC分类号： A61B3/10 , A61B3/12 , A61B3/14 , A61B5/026
CPC分类号： A61B5/0261 , A61B3/1225 , A61B3/1233 , A61B3/145
摘要： An ophthalmological diagnosis method and an apparatus for carrying out the method is disclosed. According to the invention, one of a plurality of laser beams is selected depending upon the tissue layers in the eye fundus to be diagnosed, and is projected thereon. Light is scattered by blood cells within a tissue layer of the eye fundus that depends upon the wavelength of the selected laser beam. The scattered light is received and photoelectrically converted into an electrical signal, which is then evaluated to measure the blood flow state within the tissue layer of the eye fundus.

14. 发明授权

US4952050A Ophthalmological diagnosis method and apparatus 失效
标题翻译：眼科诊断方法及装置
公开(公告)号：US4952050A
公开(公告)日：1990-08-28
申请号：US337393
申请日：1989-04-13
申请人： Yoshihisa Aizu , Kouji Ogino , Toshiaki Sugita
发明人： Yoshihisa Aizu , Kouji Ogino , Toshiaki Sugita
IPC分类号： A61B3/10 , A61B3/12 , A61B3/14
CPC分类号： A61B3/1233
摘要： Disclosed is an ophthalomological diagnosis method and apparatus in which a blood vessel in the eye fundus is illuminated with a laser beam of a predetermined beam spot whose diameter is substantially equal to or smaller than that of the blood vessel in order to produce diffraction-plane speckles which are formed at a Fourier-transform plane by light scattered from the eye fundus. Boiling motion of the diffraction-plane speckle pattern thus produced is then detected through a multiple detection aperture pattern which is disposed at the Fourier-transform plane and comprised of a plurality of small apertures to obtain a speckle signal which is evaluated to measure velocity of the blood flowing through the blood vessel concerned. This arrangement makes it possible to detect the speckle signal without any effect of averaging the signal with an increase in intensity detected, thus enabling advantageous and successful measurement of the blood flow state in the eye fundus.

15. 发明授权

US4848897A Ophthalmological diagnosis apparatus 失效
标题翻译：眼科诊断仪
公开(公告)号：US4848897A
公开(公告)日：1989-07-18
申请号：US174840
申请日：1988-03-29
申请人： Yoshihisa Aizu , Kouji Ogino , Toshiaki Sugita
发明人： Yoshihisa Aizu , Kouji Ogino , Toshiaki Sugita
IPC分类号： A61B3/10 , A61B3/12
CPC分类号： A61B3/1225
摘要： An ophthalmological diagnosis apparatus is disclosed that has an optical spatial frequency filter, a double diffraction optical system whereby an eye fundus image formed at a first image plane that is conjugate with the eye fundus is again formed at a second image plane, a magnifying optical system for expanding the eye fundus image formed on the second image plane, and a detecting aperture for detecting movement of laser speckles formed at the image plane of magnifying optical system as fluctuations in the intensity of the speckle light. Advantages of the apparatus include the ease with which a single, specific blood vessel can be selected; unnecessary light components can be filtered out, improving the S/N ratio of the speckle light detection; the optical system does not need to be high-precision; good operability; and measurement results that are much more reliable and reproducible.

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