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11. 发明授权

US07837682B2 Device and method for positioning of a therapeutic device 失效
标题翻译：用于定位治疗装置的装置和方法
公开(公告)号：US07837682B2
公开(公告)日：2010-11-23
申请号：US11397519
申请日：2006-04-04
申请人： Isaac Ostrovsky , Ty Fairneny , Victor Shukhat , Alfred Intoccia , Jon T. McIntyre
发明人： Isaac Ostrovsky , Ty Fairneny , Victor Shukhat , Alfred Intoccia , Jon T. McIntyre
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B90/39 , A61B2017/00805 , A61B2034/2051 , A61B2090/3929 , A61F2/005 , A61F2250/0001
摘要： A system comprises a first signal handling unit sized and shaped for insertion to a reference distance within a first body cavity and a probe sized and shaped for insertion into a second body cavity the probe including an energy emitting head and a second signal handling unit, wherein one of the first and second signal handling units comprises a transmitter and the other of the first and second signal handling units comprises one of a receiver adapted to receive signals from the transmitter and a signal reflecting element, wherein, when the other of the first and second signal handling units comprises a signal reflecting element, the one of the first and second signal handling units comprises a receiver in combination with a controller operatively connected to the receiver, the controller generating an output varying as a distance between the first and second signal handling units varies. In addition, a system comprises a probe sized and shaped for insertion in a first body cavity and a measuring element extending from the probe to contact tissue adjacent to an opening to a second body cavity, the measuring element being movably coupled to the probe to vary a depth to which the probe may be inserted into the first body cavity before the measuring element contacts the tissue adjacent to the opening of the second body cavity.
摘要翻译：一种系统包括第一信号处理单元，其尺寸和形状适于插入第一体腔内的参考距离;以及尺寸和形状适于插入第二体腔的探针，所述探针包括能量发射头和第二信号处理单元，其中第一信号处理单元和第二信号处理单元之一包括发送器，第一和第二信号处理单元中的另一个包括适于从发送器接收信号的接收器和信号反射元件中的一个，其中，当第一和第二信号处理单元第二信号处理单元包括信号反射元件，第一和第二信号处理单元之一包括与可操作地连接到接收器的控制器组合的接收器，所述控制器产生以第一和第二信号处理之间的距离变化的输出单位不一。此外，系统包括尺寸和形状适于插入第一体腔中的探针和从探针延伸到与第二体腔的开口相邻的接触组织的测量元件，测量元件可移动地联接到探针以变化在测量元件接触与第二体腔的开口相邻的组织之前，探针可以插入到第一体腔中的深度。

12. 发明授权

US07517346B2 Radio frequency ablation system with integrated ultrasound imaging 有权
标题翻译：射频消融系统与集成超声成像
公开(公告)号：US07517346B2
公开(公告)日：2009-04-14
申请号：US11053344
申请日：2005-02-08
申请人： Todd Sloan , Isaac Ostrovsky , Jon T. McIntyre
发明人： Todd Sloan , Isaac Ostrovsky , Jon T. McIntyre
IPC分类号： A61B18/14 , A61B8/12
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432 , A61B2090/378 , A61B2090/3782
摘要： A tissue ablation system comprises a first electrode assembly adapted for insertion into a target tissue mass within a body, the first electrode assembly including a first electrode coupled to a source of RF energy in combination with an ultrasound imaging probe movably coupled to the first electrode assembly for insertion with the first electrode assembly to a desired location relative to the target tissue mass, the probe being movable relative to the first electrode assembly between an insertion configuration in which a distal end of the probe covers a distal end of the first electrode assembly and a deployed configuration in which the distal end of the first electrode assembly is uncovered. A method of ablating target tissue within a body comprises placing a distal dome of an ultrasound imaging probe in overlying alignment with a first cannula of an RF ablation device and inserting the probe and the RF ablation device through a lumen of an insertion device to a desired location adjacent to a target tissue mass in combination with moving the distal dome away from a distal end of the first cannula to expose a distal end thereof, inserting the distal end of the first cannula into the target tissue mass to position a first electrode of the RF ablation device at a first desired location within the target tissue mass, obtaining an image of the target tissue mass and the first electrode via the probe and applying RF energy to the target tissue mass via the first electrode.
摘要翻译：组织消融系统包括适于插入到体内的靶组织块中的第一电极组件，所述第一电极组件包括耦合到RF能量源的第一电极与可移动地联接到第一电极组件的超声成像探头组合为了将第一电极组件相对于目标组织块插入到期望的位置，探针可相对于第一电极组件在插入构造之间移动，其中探针的远端覆盖第一电极组件的远端和展开构造，其中第一电极组件的远端未被覆盖。消除体内靶组织的方法包括将超声成像探针的远侧圆顶放置在与RF消融装置的第一插管对齐的位置上，并将探针和RF消融装置插入穿过插入装置的内腔至期望的将目标组织块的位置与移动远端圆顶远离第一插管的远端结合以暴露其远端的位置，将第一插管的远端插入目标组织块中以将第一电极 RF消融装置，其经由所述探针获得所述目标组织质量和所述第一电极的图像，并且经由所述第一电极向所述目标组织块施加RF能量。

13. 发明授权

US09192744B2 Controlling movement of distal portion of medical device 有权
标题翻译：控制医疗器械远端部位的运动
公开(公告)号：US09192744B2
公开(公告)日：2015-11-24
申请号：US13490199
申请日：2012-06-06
申请人： Isaac Ostrovsky , Jon T. McIntyre , Jozef Slanda
发明人： Isaac Ostrovsky , Jon T. McIntyre , Jozef Slanda
IPC分类号： A61M37/00 , A61M25/01 , A61B1/005
CPC分类号： A61M25/0136 , A61B1/0052 , A61M25/0147 , Y10T16/476
摘要： A medical device allows movement control of a distal end portion of the medical device and is adapted for one-handed operation. The medical device is capable of omni-directional control of the distal end portion of the device. The device has an elongated member including a deflectable portion at a distal end portion of the elongated member. The device also has a control portion disposed on the elongated member. This control portion can be a handle for one-handed use by an operator of the medical device. The control portion comprises an elastic element and a flexible element. Angular movement of a first portion of the control portion with respect to a second portion of the control portion results in amplification of that angular movement in the deflectable portion of the device.
摘要翻译：医疗装置允许医疗装置的远端部分的移动控制，并且适于单手操作。医疗装置能够对装置的远端部进行全方位的控制。该装置具有细长构件，该细长构件包括在细长构件的远端部分处的可偏转部分。该装置还具有设置在细长构件上的控制部分。该控制部可以是由医疗装置的操作者单手使用的手柄。控制部分包括弹性元件和柔性元件。控制部分的第一部分相对于控制部分的第二部分的角运动导致装置的可偏转部分中的该角度运动的放大。

14. 发明授权

US08845522B2 Medical instrument with a deflectable distal portion 有权
标题翻译：具有可偏转远端部分的医疗器械
公开(公告)号：US08845522B2
公开(公告)日：2014-09-30
申请号：US12191485
申请日：2008-08-14
申请人： Jon T. McIntyre , Jessica Hixon , Isaac Ostrovsky , Jozef Slanda
发明人： Jon T. McIntyre , Jessica Hixon , Isaac Ostrovsky , Jozef Slanda
IPC分类号： A61B1/00 , A61B1/005 , A61B1/04
CPC分类号： A61B1/0055 , A61B1/00098 , A61B1/0052
摘要： A deflection assembly of a medical instrument (such as an endoscope or a flexible ureteroscope) allows an operator to deflect a distal portion of the instrument using one or more controls located at a proximal portion of the instrument. The instrument allows the operator to achieve multi-directional deflection of the distal portion.
摘要翻译：医疗器械（例如内窥镜或柔性输尿管镜）的偏转组件允许操作者使用位于仪器的近端部分的一个或多个控制器偏转仪器的远端部分。仪器允许操作者实现远端部分的多方向偏转。

15. 发明授权

US09533176B2 Device and method for detecting and treating lesions 有权
标题翻译：用于检测和治疗病变的装置和方法
公开(公告)号：US09533176B2
公开(公告)日：2017-01-03
申请号：US12249134
申请日：2008-10-10
申请人： Isaac Ostrovsky , Jon T. McIntyre , Ty Fairneny , Victor Shukhat , Michael Madden
发明人： Isaac Ostrovsky , Jon T. McIntyre , Ty Fairneny , Victor Shukhat , Michael Madden
IPC分类号： A61B5/05 , A61N7/02 , A61B5/00 , A61B17/00 , A61B18/00
CPC分类号： A61N7/022 , A61B5/0084 , A61B5/4325 , A61B2017/00061 , A61B2018/00023 , A61B2090/306
摘要： A device for treating tissue comprises an enlongate probe and a light delivery unit illuminating a target area with light within a first wavelength band selected to enhance identification of target tissue in combination with an ultrasound crystal mounted at a distal end of the probe, the crystal being stimulated to treat target tissue identified using the light delivery unit.
摘要翻译：一种用于治疗组织的装置，包括一个扩大的探针和一个光输送单元，用一个第一波长带内的光照射一个目标区域，以便与安装在该探头的远端的超声波晶体结合，以增强目标组织的识别，该晶体是刺激以治疗使用光输送单元鉴定的靶组织。

16. 发明申请

US20120220995A1 SYSTEM AND METHOD FOR TISSUE ABLATION 审中-公开
标题翻译：用于组织消融的系统和方法
公开(公告)号：US20120220995A1
公开(公告)日：2012-08-30
申请号：US13423207
申请日：2012-03-17
申请人： Isaac Ostrovsky , Jon T. McIntyre
发明人： Isaac Ostrovsky , Jon T. McIntyre
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/1482 , A61B18/14 , A61B18/1442 , A61B18/1815 , A61B2018/00273 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1432 , A61B2018/1435 , A61B2018/1467 , A61B2018/1475
摘要： A tissue ablation device comprises first and second electrodes of opposite polarities, the first electrode being mounted to a first elongated member for movement relative to the second electrode for separation therefrom by a desired distance. A method of ablating a tissue comprises inserting first and second electrodes to desired initial positions relative to a tissue mass to be ablated and applying electrical energy to the first and second electrodes to ablate a first portion of tissue between the first and second electrodes in combination with the step of applying electrical energy to desired second positions separated from the desired initial positions by a distance selected to transfer electrical energy around the first portion of tissue through a second portion of tissue to be ablated, the second portion of tissue surrounding the first portion of tissue.
摘要翻译：组织消融装置包括具有相反极性的第一和第二电极，第一电极被安装到第一细长构件，以相对于第二电极移动，以便将其与之隔离一段期望的距离。消融组织的方法包括将第一和第二电极相对于要消融的组织块插入所需的初始位置，并将电能施加到第一和第二电极，以将第一和第二电极之间的组织的第一部分与将电能施加到从期望的初始位置分离所需的第二位置的距离，所述距离被选择为通过待消融的组织的第二部分转移围绕组织的第一部分的电能，围绕第一部分的组织的第二部分组织。

17. 发明申请

US20110009700A1 CONTROLLING MOVEMENT OF DISTAL PORTION OF MEDICAL DEVICE 有权
标题翻译：控制医疗器械远程部位的运动
公开(公告)号：US20110009700A1
公开(公告)日：2011-01-13
申请号：US12839267
申请日：2010-07-19
申请人： Isaac OSTROVSKY , Jon T. McIntyre , Jozef Slanda
发明人： Isaac OSTROVSKY , Jon T. McIntyre , Jozef Slanda
IPC分类号： A61B1/005 , A61M25/00
CPC分类号： A61M25/0136 , A61B1/0052 , A61M25/0147 , Y10T16/476
摘要： A medical device allows movement control of a distal end portion of the medical device and is adapted for one-handed operation. The medical device is capable of omni-directional control of the distal end portion of the device. The device has an elongated member including a deflectable portion at a distal end portion of the elongated member. The device also has a control portion disposed on the elongated member. This control portion can be a handle for one-handed use by an operator of the medical device. The control portion comprises an elastic element and a flexible element. Angular movement of a first portion of the control portion with respect to a second portion of the control portion results in amplification of that angular movement in the deflectable portion of the device.
摘要翻译：医疗装置允许医疗装置的远端部分的移动控制，并且适于单手操作。医疗装置能够对装置的远端部进行全方位的控制。该装置具有细长构件，该细长构件包括在细长构件的远端部分处的可偏转部分。该装置还具有设置在细长构件上的控制部分。该控制部可以是由医疗装置的操作者单手使用的手柄。控制部分包括弹性元件和柔性元件。控制部分的第一部分相对于控制部分的第二部分的角运动导致装置的可偏转部分中的角运动的放大。

18. 发明申请

US20090240109A1 FLEXIBLE ENDOSCOPE WITH CORE MEMBER 审中-公开
标题翻译：具有核心成员的灵活内窥镜
公开(公告)号：US20090240109A1
公开(公告)日：2009-09-24
申请号：US12408881
申请日：2009-03-23
申请人： Isaac Ostrovsky , Jon T. McIntyre , Ty Fairneny , Alfred Intoccia , Jessica Hixon
发明人： Isaac Ostrovsky , Jon T. McIntyre , Ty Fairneny , Alfred Intoccia , Jessica Hixon
IPC分类号： A61B1/04
CPC分类号： A61B1/0051 , A61B1/00071 , A61B1/00078 , A61B1/00137 , A61B1/00165 , A61B1/0055 , A61B1/05
摘要： A digital imaging endoscope with an elongated shaft has a core member for imparting flexibility and column strength to the shaft. The shaft extends distally from a proximal handle, and at least part of the shaft, or the entire shaft, comprises an inner member, the core member, and an outer member. The inner member defines at least three lumens. A first lumen is for receiving an instrument, a second lumen is for receiving one or more wires for connecting a digital imaging device at a distal portion of the shaft to a display unit, and a third lumen is for receiving the core member. The core member can occupy the space within the shaft that was traditionally occupied by a fiber optic bundle in non-digital imaging endoscopes. The outer member is disposed over the inner member of the shaft, and the outer member defines a lumen through which the inner member extends.
摘要翻译：具有细长轴的数字成像内窥镜具有用于向轴赋予柔性和柱强度的芯构件。轴从近侧手柄向远侧延伸，并且轴的至少一部分或整个轴包括内部构件，芯部构件和外部构件。内部构件限定至少三个流明。第一内腔用于接收仪器，第二腔用于接收用于将轴的远端部分处的数字成像装置连接到显示单元的一个或多个导线，并且第三内腔用于容纳所述芯部件。芯构件可以占据在非数字成像内窥镜中传统上由光纤束占据的轴内的空间。外部构件设置在轴的内部构件上，并且外部构件限定内部构件，内部构件延伸穿过该内腔。

19. 发明申请

US20080275370A1 APPARATUS AND METHOD FOR TREATING VISUAL DISORDERS 审中-公开
标题翻译：用于治疗视力障碍的装置和方法
公开(公告)号：US20080275370A1
公开(公告)日：2008-11-06
申请号：US11742644
申请日：2007-05-01
申请人： Jon T. McIntyre , Isaac Ostrovsky , Victor Shukhat
发明人： Jon T. McIntyre , Isaac Ostrovsky , Victor Shukhat
IPC分类号： A61N7/00
CPC分类号： A61F9/00745
摘要： In one embodiment, an apparatus includes an elongate body having a proximal end and a distal end and an ultrasound transducer coupled to the distal end of the elongate body. A cooling member is coupled to the ultrasound transducer. The cooling member and/or the ultrasound transducer is configured to directly contact an outer surface of an eye such that ultrasound energy can be applied to a targeted portion of the eye. A method includes disposing a medical device such that a distal end of the medical device is in contact with an outer surface of an eye. The medical device includes an elongate body and an ultrasound transducer coupled to a distal end of the elongate body. Ultrasound energy is applied to a targeted portion of the eye while the medical device is disposed in contact with the outer surface of the eye to reshape the cornea of the eye.
摘要翻译：在一个实施例中，一种装置包括具有近端和远端的细长主体和耦合到细长主体的远端的超声换能器。冷却构件联接到超声换能器。冷却构件和/或超声换能器构造成直接接触眼睛的外表面，使得超声能量可以施加到眼睛的目标部分。一种方法包括设置医疗装置，使得医疗装置的远端与眼睛的外表面接触。医疗装置包括细长主体和耦合到细长主体的远端的超声换能器。将超声能量施加到眼睛的目标部分，同时将医疗装置设置成与眼睛的外表面接触以重塑眼睛的角膜。

20. 发明授权

US09675821B2 Device for thermal treatment of tissue and for temperature measurement of tissue providing feedback 有权
公开(公告)号：US09675821B2
公开(公告)日：2017-06-13
申请号：US11374811
申请日：2006-03-14
申请人： Isaac Ostrovsky , Victor Shukhat , Alfred P. Intoccia , Jon T. McIntyre , Ty Fairneny
发明人： Isaac Ostrovsky , Victor Shukhat , Alfred P. Intoccia , Jon T. McIntyre , Ty Fairneny
IPC分类号： A61N7/02 , A61B17/00 , A61N7/00 , A61B90/00
CPC分类号： A61N7/022 , A61B2017/00084 , A61B2090/378 , A61N2007/0078
摘要： A device for heating tissue, comprises a housing sized for insertion through a naturally occurring body orifice to a target location within a lumen and a heat generating element within the housing focusing thermal energy on a target area separated from an outside of the housing so that, when the housing is in the target location, the target area is within tissue surrounding the lumen at a predetermined depth from a lumenal wall in combination with a temperature sensing element sensing data corresponding to a temperature of tissue in the target area and a processor controlling the heat generating element in response to the data sensed by the sensing element.

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