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11. 发明授权

US06436046B1 Diagnostic ultrasound imaging method and system with improved frame rate 有权
标题翻译：诊断超声成像方法和系统，帧率提高
公开(公告)号：US06436046B1
公开(公告)日：2002-08-20
申请号：US09698995
申请日：2000-10-27
申请人： David J. Napolitano , Christopher R. Cole , Gregory L. Holley , John A. Hossack , Charles E. Bradley , Patrick Phillips
发明人： David J. Napolitano , Christopher R. Cole , Gregory L. Holley , John A. Hossack , Charles E. Bradley , Patrick Phillips
IPC分类号： A61B800
CPC分类号： G01S15/8963 , A61B8/00 , G01S7/52039 , G01S7/52046 , G01S7/52085 , G01S7/52095 , G01S15/8927 , G01S15/8959 , G01S15/8977
摘要： A medical diagnostic ultrasonic imaging system acquires receive beams from spatially distinct transmit beams. The receive beams alternate in type between at least first and second types across the region being imaged. The first and second types of receive beams differ in at least one scan parameter other than transmit and receive line geometry, and can for example differ in transmit phase, transmit or receive aperture, system frequency, transmit focus, complex phase angle, transmit code or transmit gain. Receive beams associated with spatially distinct ones of the transmit beams (including at least one beam of the first type and at least one beam of the second type) are then combined. In this way, many two-pulse techniques, including, for example, phase inversion techniques, synthetic aperture techniques, synthetic frequency techniques, and synthetic focus techniques, can be used while substantially reducing the frame rate penalty normally associated with such techniques.
摘要翻译：医疗诊断超声成像系统从空间上不同的发射波束获取接收波束。接收波束在被成像的区域之间在至少第一和第二类型之间交替类型。第一和第二类型的接收波束在除发射和接收线几何之外的至少一个扫描参数不同，并且例如可以在发射相位，发射或接收孔径，系统频率，发射焦点，复相位角，发射码或传输增益。然后组合与空间上不同的发射波束（包括第一类型的至少一个波束和第二类型的至少一个波束）相关联的接收波束。以这种方式，可以使用许多双脉冲技术，包括例如相位反转技术，合成孔径技术，合成频率技术和合成焦点技术，同时显着降低通常与这种技术相关联的帧速率损失。

12. 发明授权

US06241674B1 Medical ultrasound diagnostic imaging method and system with nonlinear phase modulation pulse compression 有权
标题翻译：医学超声诊断成像方法和系统具有非线性相位调制脉冲压缩
公开(公告)号：US06241674B1
公开(公告)日：2001-06-05
申请号：US09282510
申请日：1999-03-31
申请人： Patrick Phillips , Gregory L. Holley , David J. Napolitano , Kutay F. Ustuner
发明人： Patrick Phillips , Gregory L. Holley , David J. Napolitano , Kutay F. Ustuner
IPC分类号： A61B800
CPC分类号： G01S15/8959 , A61B8/08 , G01S7/52038
摘要： A medical ultrasonic diagnostic imaging method and apparatus uses a phased array transducer probe to transmit a fundamental coded ultrasonic pulse into a tissue. This pulse has a time-bandwidth product that is greater than 1 but less than 100. A receiver is coupled to the probe to receive an Nth harmonic echo signal from the tissue, and a compression filter compresses the harmonic echo signal with a compression function having a phase that varies about N times as fast as the fundamental coded ultrasonic pulse. In this way, the SNR of the resulting image is increased. The disclosed method and apparatus are particularly well adapted for use with tissue harmonic imaging, because of the typically low SNR characteristic of such imaging. Other aspects are well-suited for imaging with non-linear contrast agents.
摘要翻译：医用超声诊断成像方法和装置使用相控阵传感器探头将基本编码超声波脉冲发送到组织中。该脉冲具有大于1但小于100的时间带宽乘积。接收器耦合到探头以从组织接收第N次谐波回波信号，并且压缩滤波器以压缩函数压缩谐波回波信号，该压缩函数具有其变化大约是基本编码超声波脉冲的N倍。以这种方式，所得图像的SNR增加。由于这种成像的典型的低SNR特性，所公开的方法和装置特别适用于组织谐波成像。其他方面非常适合用非线性造影剂进行成像。

13. 发明授权

US6050944A Method and apparatus for frequency control of an ultrasound system 失效
公开(公告)号：US6050944A
公开(公告)日：2000-04-18
申请号：US904829
申请日：1997-08-01
申请人： Gregory L. Holley , Paul E. Chandler
发明人： Gregory L. Holley , Paul E. Chandler
IPC分类号： A61B8/08 , A61B8/14 , G01S7/52 , G01S15/89 , A61B8/00 , A61B8/06
CPC分类号： A61B8/14 , A61B8/461 , A61B8/467 , A61B8/488 , G01S7/52038 , G01S7/52084 , G01S15/8979
摘要： A method and system for acquiring data in an ultrasound system are provided. A transducer is operatively connected to a transmit beamformer and a receive beamformer. The receive beamformer is configured to obtain a first value associated with a fundamental frequency interleaved with a second value associated with a harmonic frequency. A first transmit signal is transmitted at a first frequency. A first echo signal is received in response to the first transmit signal. At least the first value associated with the first frequency is obtained from the first echo signal. An interleaved second transmit signal is transmitted at the first frequency or a second frequency. A second echo signal is received in response to the second transmit signal. At least the second value associated with a third frequency is obtained from the second echo signal. Images are generated and displayed based on the at least one first value and the at least one second value.

14. 发明授权

US5957845A Gated ultrasound imaging apparatus and method 有权
公开(公告)号：US5957845A
公开(公告)日：1999-09-28
申请号：US159527
申请日：1998-09-23
申请人： Gregory L. Holley , Richard M. Bennett , Edward A. Gardner , Samuel H. Maslak
发明人： Gregory L. Holley , Richard M. Bennett , Edward A. Gardner , Samuel H. Maslak
IPC分类号： A61B5/0456 , A61B8/00 , G01S7/52 , G01S15/89
CPC分类号： A61B8/481 , A61B8/543 , G01S7/52025 , G01S7/52038 , G01S7/52085 , G01S7/52087 , A61B5/0456 , G01S15/895 , G01S7/52074
摘要： An ultrasound imaging system is programmed to acquire first ultrasonic image frames intermittently. These first frames, typically triggered frames synchronized with a selected portion of an ECG cycle, are optimized for high image quality of a contrast agent included in the tissue. The imaging system automatically acquires second ultrasonic image frames between at least some of the first frames. The second image frames are typically locator frames which are optimized for reduced degradation of the contrast agent. More of the second frames are acquired per unit time than first frames, and both the first and second frames are displayed, either superimposed over one another or in side-by-side relationship. In this way the user is provided with substantially continuous transducer locating information, yet contrast agent destruction between acquisitions of the first, triggered frames is reduced or eliminated.

15. 发明授权

US06626831B2 Gated ultrasound imaging apparatus and method 有权
标题翻译：门式超声成像设备及方法
公开(公告)号：US06626831B2
公开(公告)日：2003-09-30
申请号：US09767189
申请日：2001-01-22
申请人： Gregory L. Holley , Richard M. Bennett , Edward A. Gardner , Samuel H. Maslak
发明人： Gregory L. Holley , Richard M. Bennett , Edward A. Gardner , Samuel H. Maslak
IPC分类号： A61B800
CPC分类号： A61B8/481 , A61B5/0456 , A61B8/543 , G01S7/52025 , G01S7/52038 , G01S7/52074 , G01S7/52085 , G01S7/52087 , G01S15/895
摘要： An ultrasound imaging system is programmed to acquire first ultrasonic image frames intermittently. These first frames, typically triggered frames synchronized with a selected portion of an ECG cycle, are optimized for high image quality of a contrast agent included in the tissue. The imaging system automatically acquires second ultrasonic image frames between at least some of the first frames. The second image frames are typically locator frames which are optimized for reduced degradation of the contrast agent. More of the second frames are acquired per unit time than first frames, and both the first and second frames are displayed, either superimposed over one another or in side-by-side relationship. In this way the user is provided with substantially continuous transducer locating information, yet contrast agent destruction between acquisitions of the first, triggered frames is reduced or eliminated.
摘要翻译：超声成像系统被编程为间歇地获取第一超声图像帧。这些第一帧，通常是与ECG周期的选定部分同步的触发帧，被优化用于组织中包括的造影剂的高图像质量。成像系统在至少一些第一帧之间自动获取第二超声图像帧。第二图像帧通常是定位器帧，其被优化用于造影剂的降低降低。与第一帧相比，每单位时间获取更多的第二帧，并且显示第一和第二帧，或者彼此叠加或并排关系。以这种方式，向用户提供基本上连续的换能器定位信息，但是减少或消除了第一触发帧的获取之间的造影剂破坏。

16. 发明授权

US06312379B1 Ultrasonic harmonic imaging system and method using waveform pre-distortion 失效
标题翻译：超声波谐波成像系统及方法采用波形预失真
公开(公告)号：US06312379B1
公开(公告)日：2001-11-06
申请号：US09061014
申请日：1998-04-15
申请人： Charles E. Bradley , Gregory L. Holley , Lawrence J. Newell , David J. Hedberg , Dave Napolitano
发明人： Charles E. Bradley , Gregory L. Holley , Lawrence J. Newell , David J. Hedberg , Dave Napolitano
IPC分类号： A61D800
CPC分类号： G01S7/52039 , G01S7/52038 , G01S7/52046 , G01S15/895
摘要： Improvements to a method for imaging a target, which method including the steps of (a) transmitting ultrasonic energy at a fundamental frequency, (b) receiving reflected ultrasonic energy at a harmonic of the fundamental frequency and (c) generating an image responsive to reflected energy at the harmonic, are provided. The transmitting step includes transmitting a waveform with a positive pulse spatially defined by first and second zero values. A positive peak amplitude of the positive pulse is a first distance from the first zero value that is less than half a second distance between said first and second zero values. Thus, the waveform includes a fundamental spectral component and a harmonic spectral component at the transducer. An attenuation normalized peak of the harmonic spectral component is reduced at a region spaced from the transducer as compared to the peak at a region adjacent to the transducer. A negative peak is also shifted or pre-distorted. Various pre-distortions of the waveform may compensate for propagation, scattering, or system non-linearities.
摘要翻译：用于对目标成像的方法的改进，该方法包括以下步骤：（a）以基本频率发送超声能量，（b）在基频谐波处接收反射的超声波能量，以及（c）响应于反射的提供谐波的能量。发送步骤包括以由第一和第二零值空间定义的正脉冲发送波形。正脉冲的正峰值振幅是与第一零值之间的第一距离，该第一零值小于所述第一和第二零值之间的第二距离的一半。因此，波形包括传感器处的基本频谱分量和谐波频谱分量。与与换能器相邻的区域的峰值相比，谐振频谱分量的衰减归一化峰值在与换能器间隔的区域减小。负峰也被转移或预失真。波形的各种预失真可以补偿传播，散射或系统非线性。

17. 发明授权

US06222948B1 Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US06222948B1
公开(公告)日：2001-04-24
申请号：US09502607
申请日：2000-02-11
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

18. 发明授权

US06201900B1 Multiple ultrasound image registration system, method and transducer 有权
标题翻译：多重超声图像配准系统，方法和传感器
公开(公告)号：US06201900B1
公开(公告)日：2001-03-13
申请号：US09340542
申请日：1999-06-28
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.
摘要翻译：超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。跟踪阵列横向于图像数据阵列。来自图像数据阵列的图像用于重建目标的三维表示。基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。类似的技术估计图像平面内的运动以产生扩展的视场。

19. 发明授权

US6102865A Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US6102865A
公开(公告)日：2000-08-15
申请号：US346090
申请日：1999-07-01
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： A61B8/00 , G01S7/52 , G01S15/66 , G01S15/87 , G01S15/89 , G06T7/20 , A61B8/14
CPC分类号： A61B8/145 , A61B8/483 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G01S7/52085 , G06T7/2033 , G01S15/66 , G01S15/87 , G01S7/52034 , G01S7/52065 , G01S7/52071
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

20. 发明授权

US6045505A Method and apparatus for frequency control of an ultrasound system 有权
公开(公告)号：US6045505A
公开(公告)日：2000-04-04
申请号：US156015
申请日：1998-09-17
申请人： Gregory L. Holley , Paul E. Chandler
发明人： Gregory L. Holley , Paul E. Chandler
IPC分类号： A61B8/08 , A61B8/14 , G01S7/52 , G01S15/89 , A61B8/00
CPC分类号： A61B8/14 , A61B8/461 , A61B8/467 , A61B8/488 , G01S7/52038 , G01S7/52084 , G01S15/8979
摘要： A method and system for acquiring data in an ultrasound system are provided. A transducer is operatively connected to a transmit beamformer and a receive beamformer. The receive beamformer is configured to obtain a first value associated with a fundamental frequency interleaved with a second value associated with a harmonic frequency. A first transmit signal is transmitted at a first frequency. A first echo signal is received in response to the first transmit signal. At least the first value associated with the first frequency is obtained from the first echo signal. An interleaved second transmit signal is transmitted at the first frequency or a second frequency. A second echo signal is received in response to the second transmit signal. At least the second value associated with a third frequency is obtained from the second echo signal. Images are generated and displayed based on the at least one first value and the at least one second value.

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