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11. 发明申请

US20120246278A1 DYNAMIC MEDIA SERVING INFRASTRUCTURE 有权
标题翻译：动态媒体服务基础设施
公开(公告)号：US20120246278A1
公开(公告)日：2012-09-27
申请号：US13486881
申请日：2012-06-01
申请人： Manish Gupta , John Harding , Stephen M. Lacy , Willard Rusch, II
发明人： Manish Gupta , John Harding , Stephen M. Lacy , Willard Rusch, II
IPC分类号： G06F15/16
CPC分类号： H04N21/44012 , G06Q30/0242 , H04N21/23412 , H04N21/2343 , H04N21/4325 , H04N21/6581
摘要： Systems and methods provide for dynamic generation of media content at the point that content is served. The system and method work within the bounds of simple, existing, open protocols and the media files served are playable by standard media playback clients. The method is driven by a request for media content from a client specifying an edit list. The server opens one or more source files and selects portions of one or more files to transmit based on edit list instructions, and sequentially writes those portions to an output for serving to the client. The method allows for various modifications of the content before serving.
摘要翻译：系统和方法提供在内容被服务的时刻动态生成媒体内容。系统和方法在简单，现有，开放协议的范围内工作，并且提供的媒体文件可以由标准媒体播放客户端播放。该方法由来自指定编辑列表的客户端的媒体内容的请求驱动。服务器打开一个或多个源文件，并根据编辑列表指令选择要发送的一个或多个文件的部分，并将这些部分顺序地写入到用于服务的服务的输出。该方法允许在服务之前对内容的各种修改。

12. 发明授权

US07976042B2 Retractable step 有权
标题翻译：伸缩步骤
公开(公告)号：US07976042B2
公开(公告)日：2011-07-12
申请号：US11841280
申请日：2007-08-20
申请人： Bradley E. Watson , Charles J. Chuba , Ben Yang , John Harding , Christopher J. Kuntze , Trevor Thompson
发明人： Bradley E. Watson , Charles J. Chuba , Ben Yang , John Harding , Christopher J. Kuntze , Trevor Thompson
IPC分类号： B60R3/02
CPC分类号： B60R3/02
摘要： A step assembly includes an upper housing adapted to be fixedly secured to the motor vehicle. A step is movable relative to the upper housing between a stowed position and a deployed position. A single arm is pivotal with respect to the upper housing and pivotal with respect to the step in order to form a three-bar linkage for moving the step between the stowed and deployed positions.
摘要翻译：台阶组件包括适于固定地固定在机动车辆上的上壳体。台阶可相对于上壳体在收起位置和展开位置之间移动。单臂相对于上壳体枢转并且相对于台阶枢转，以形成用于在收起位置和展开位置之间移动台阶的三杆连杆。

13. 发明授权

US07504206B2 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs 有权
标题翻译：断奶多系统消耗综合征和猪圆环病毒猪
公开(公告)号：US07504206B2
公开(公告)日：2009-03-17
申请号：US11217562
申请日：2005-09-01
申请人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly , Li Wang , Lorne A. Babiuk , Andrew A. Potter , Philip Willson
发明人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly , Li Wang , Lorne A. Babiuk , Andrew A. Potter , Philip Willson
IPC分类号： C12Q1/70 , A61K39/12
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , A61K2039/51 , A61K2039/53 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2750/10022 , C12N2750/10034 , C12N2750/10043 , C12Q1/701
摘要： The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.
摘要翻译：新型PCVII病毒基因组的克隆描述为源自PCVII基因组的蛋白质的表达。这些蛋白质可用于预防和治疗PCVII感染的疫苗组合物中，以及用于确定脊椎动物受试者中PCVII感染存在的诊断方法。衍生自病毒基因组的多核苷酸可用作诊断引物和探针。

14. 发明申请

US20090008894A1 STEP ASSIST BOX-SIDE 有权
公开(公告)号：US20090008894A1
公开(公告)日：2009-01-08
申请号：US11666722
申请日：2005-10-31
申请人： Christopher J. Kuntze , Brad E. Watson , Dan Glovak , John Harding , Randy Bolt
发明人： Christopher J. Kuntze , Brad E. Watson , Dan Glovak , John Harding , Randy Bolt
IPC分类号： B60R3/02
CPC分类号： B60R3/002 , B60R3/02
摘要： A step assembly is provided for a bumper of a motor vehicle. The step assembly includes a mounting bracket fixedly secured to the bumper. A step is operatively coupled to the mounting bracket and is movable between a retracted position disposed adjacent the bumper and a deployed position extending away from the bumper. A pivot arm is pivotally interconnected between the mounting bracket and the step. A spring is secured between the mounting bracket and the pivot arm for biasing the pivot arm. The spring creates a tensile force. A lock arm is pivotally interconnected between the mounting bracket and the step. The lock arm defines a lock surface engaging the pivot arm while the tensile force of the spring locks the step in order to retain the step in one of the retracted and deployed positions.
摘要翻译：提供了用于机动车辆的保险杠的步进组件。台阶组件包括固定地固定在保险杠上的安装支架。一个步骤可操作地联接到安装支架，并且可以在靠近保险杠设置的缩回位置和远离保险杠的展开位置之间移动。枢转臂在安装支架和台阶之间枢转地互连。弹簧被固定在安装支架和枢转臂之间，用于偏压枢转臂。弹簧产生张力。锁定臂在安装支架和台阶之间枢转地互连。锁定臂限定与枢转臂接合的锁定表面，同时弹簧的张力锁定该台阶以便将该台阶保持在缩回和展开位置之一中。

15. 发明授权

US07192594B2 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs 有权
标题翻译：断奶多系统消耗综合征和猪圆环病毒猪
公开(公告)号：US07192594B2
公开(公告)日：2007-03-20
申请号：US10653849
申请日：2003-09-02
申请人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly , Li Wang , Lorne A. Babiuk , Andrew A. Potter , Philip Willson
发明人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly , Li Wang , Lorne A. Babiuk , Andrew A. Potter , Philip Willson
IPC分类号： A61K39/12
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , A61K2039/51 , A61K2039/53 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2750/10022 , C12N2750/10034 , C12N2750/10043 , C12Q1/701
摘要： The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.
摘要翻译：新型PCVII病毒基因组的克隆描述为源自PCVII基因组的蛋白质的表达。这些蛋白质可用于预防和治疗PCVII感染的疫苗组合物中，以及用于确定脊椎动物受试者中PCVII感染存在的诊断方法。衍生自病毒基因组的多核苷酸可用作诊断引物和探针。

16. 发明申请

US20050058653A1 Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2 有权
标题翻译：预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染
公开(公告)号：US20050058653A1
公开(公告)日：2005-03-17
申请号：US10780318
申请日：2004-02-17
申请人： John Ellis , Gordon Allan , Brian Meehan , Edward Clark , Deborah Haines , Lori Hassard , John Harding , Catherine Charreyre , Gilles Chappuis , George Krakowka , Jean-Christophe Audonnet , Francis McNeilly
发明人： John Ellis , Gordon Allan , Brian Meehan , Edward Clark , Deborah Haines , Lori Hassard , John Harding , Catherine Charreyre , Gilles Chappuis , George Krakowka , Jean-Christophe Audonnet , Francis McNeilly
IPC分类号： A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , C07K14/01 , C12N7/00
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , A61K2039/51 , A61K2039/5252 , A61K2039/5256 , A61K2039/53 , A61K2039/552 , A61K2039/55566 , C12N7/00 , C12N2710/10343 , C12N2710/16743 , C12N2710/24043 , C12N2750/10022 , C12N2750/10034
摘要： Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6th and 8th and/or the 10th and 13th weeks of gestation, can lower viral titer, prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.
摘要翻译：猪圆环病毒-2（PCV-2）是最近确定的药物，其中PCV-2相关疾病的潜在谱已经通过垂直和性传播的证据以及猪群体相关的生殖失败而扩大。从经历了晚期堕胎和死胎的农场的排卵仔猪中分离出PCV-2。在与PCV-2抗原的广泛免疫组织化学染色相关的一只仔猪中存在严重的弥漫性心肌炎。不同量的PCV-2抗原也存在于多个胎儿的肝，肺和肾中。包括来自PCV-2的免疫原的组合物或来自这种免疫原的感兴趣的表位的组合物的雌性猪或在繁殖之前（例如在生命的前五周内）表达这种免疫原或感兴趣的表位的载体，或在围产期，或一生以上，或怀孕期间，例如6〜8和/或10〜13周的妊娠期间，可以降低病毒滴度，预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染。此外，可以进行具有上述组成的雄性和/或雌性猪的接种，以防止在交配期间PCV-2从雄性到雌性（或反之亦然）的传播。因此，本发明涉及用于预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染的方法和组合物。

17. 发明授权

US06660272B2 Porcine circoviruses, vaccines and diagnostic reagents 有权
公开(公告)号：US06660272B2
公开(公告)日：2003-12-09
申请号：US09884514
申请日：2001-06-19
申请人： Gordon Allan , Brian Meehan , Edward Clark , John Ellis , Deborah Haines , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly
发明人： Gordon Allan , Brian Meehan , Edward Clark , John Ellis , Deborah Haines , Lori Hassard , John Harding , Catherine Elisabeth Charreyre , Gilles Emile Chappuis , Francis McNeilly
IPC分类号： A61K3912
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , A61K2039/51 , A61K2039/5252 , A61K2039/552 , A61K2039/55566 , C12N2710/10343 , C12N2710/16043 , C12N2710/24043 , C12N2750/10021 , C12N2750/10022 , C12N2750/10034 , C12N2750/10043 , C12N2750/10063 , C12N2750/10064
摘要： The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It relates to purified preparations of these strains, conventional attenuated or inactivated vaccines, recombinant live vaccines, plasmid vaccines and subunit vaccines, as well as reagents and diagnostic methods. It also relates to the DNA fragments which can be used for the production of subunits in an in vitro expression vector or as sequences to be integrated into a virus or plasmid type in vivo expression vector.

18. 发明申请

US20170024449A1 DYNAMICALLY INTEGRATED DISPARATE COMPUTER-AIDED DISPATCH SYSTEMS 审中-公开
标题翻译：动态统一的计算机辅助发送系统
公开(公告)号：US20170024449A1
公开(公告)日：2017-01-26
申请号：US15289883
申请日：2016-10-10
申请人： Jonathan K. Wesley, SR. , Erik Cooley , Nathan Daniels , John Harding , Andrew Horlacher , Ryan McAlister , Ryan Sealy , Brian Taylor
发明人： Jonathan K. Wesley, SR. , Erik Cooley , Nathan Daniels , John Harding , Andrew Horlacher , Ryan McAlister , Ryan Sealy , Brian Taylor
IPC分类号： G06F17/30 , G06F9/445 , H04L29/08
摘要： Systems and methods for dynamically integrating disparate computer-aided dispatch (CAD) systems are disclosed. The systems and methods provide bi-directional interoperability between disparate CAD systems and maintain stateful ongoing interactions between interconnected CAD systems. Information objects in one CAD system are associated and bound to related objects in other CAD systems through a centralized information hub that transforms data items intelligently to facilitate communication and interaction between the CAD systems connected to the hub. The described systems and methods maintain complete and current perspectives of all relevant information for each CAD system connected to the information hub, thereby eliminating the need for point-to-point intelligence maintained by the CAD systems about the other interconnected CAD systems. As information updates are passed from CAD systems to the information hub and back out to other CAD systems, the information hub transforms and evaluates the information updates ensuring that only necessary information updates are forwarded.
摘要翻译：公开了用于动态集成不同计算机辅助调度（CAD）系统的系统和方法。系统和方法提供了不同的CAD系统之间的双向互操作性，并保持了互连的CAD系统之间的有状态的持续交互。一个CAD系统中的信息对象通过集中式信息中心与其他CAD系统中的相关对象相关联并将其绑定到智能地转换数据项，以促进连接到集线器的CAD系统之间的通信和交互。所描述的系统和方法对于连接到信息中心的每个CAD系统保持对所有相关信息的完整和当前的观点，从而消除对CAD系统对其他互联CAD系统所保持的点对点智能的需求。随着信息更新从CAD系统传递到信息中心并返回到其他CAD系统，信息中心将转换和评估信息更新，确保仅转发必要的信息更新。

19. 发明授权

US09465839B2 Dynamically integrating disparate computer-aided dispatch systems 有权
标题翻译：动态整合不同的计算机辅助调度系统
公开(公告)号：US09465839B2
公开(公告)日：2016-10-11
申请号：US14473896
申请日：2014-08-29
申请人： Jonathan Wesley , Erik Cooley , Nathan Daniels , John Harding , Andrew Horlacher , Ryan McAlister , Ryan Sealy , Brian Taylor
发明人： Jonathan Wesley , Erik Cooley , Nathan Daniels , John Harding , Andrew Horlacher , Ryan McAlister , Ryan Sealy , Brian Taylor
IPC分类号： G06F15/16 , G06F17/30 , G06F15/173
CPC分类号： G06F17/30569 , G06F8/65 , G06F15/173 , G06F17/30424 , H04L67/34
摘要： Systems and methods for dynamically integrating disparate computer-aided dispatch (CAD) systems are disclosed. The systems and methods provide bi-directional interoperability between disparate CAD systems and maintain stateful ongoing interactions between interconnected CAD systems. Information objects in one CAD system are associated and bound to related objects in other CAD systems through a centralized information hub that transforms data items intelligently to facilitate communication and interaction between the CAD systems connected to the hub. The described systems and methods maintain complete and current perspectives of all relevant information for each CAD system connected to the information hub, thereby eliminating the need for point-to-point intelligence maintained by the CAD systems about the other interconnected CAD systems. As information updates are passed from CAD systems to the information hub and back out to other CAD systems, the information hub transforms and evaluates the information updates ensuring that only necessary information updates are forwarded.
摘要翻译：公开了用于动态集成不同计算机辅助调度（CAD）系统的系统和方法。系统和方法提供了不同的CAD系统之间的双向互操作性，并保持了互连的CAD系统之间的有状态的持续交互。一个CAD系统中的信息对象通过集中式信息中心与其他CAD系统中的相关对象相关联并将其绑定到智能地转换数据项，以促进连接到集线器的CAD系统之间的通信和交互。所描述的系统和方法对于连接到信息中心的每个CAD系统保持对所有相关信息的完整和当前的观点，从而消除对CAD系统对其他互联CAD系统所保持的点对点智能的需求。随着信息更新从CAD系统传递到信息中心并返回到其他CAD系统，信息中心将转换和评估信息更新，确保仅转发必要的信息更新。

20. 发明授权

US08234397B2 Media article adaptation to client device 有权
标题翻译：媒体文章适应客户端设备
公开(公告)号：US08234397B2
公开(公告)日：2012-07-31
申请号：US13217791
申请日：2011-08-25
申请人： Manish Gupta , John Harding , Stephen Michael Lacy , Willard Rusch, II
发明人： Manish Gupta , John Harding , Stephen Michael Lacy , Willard Rusch, II
IPC分类号： G06F15/16 , G06F15/173 , G06F15/177
CPC分类号： H04N21/4325 , H04N21/23412 , H04N21/2343 , H04N21/44012 , H04N21/6581
摘要： Systems and methods provide for on-the-fly adaptation of a send rate for content sent to a client based on a detected read rate of the client system for data previously sent. The system and method work within the bounds of simple, existing, open protocols and the media files served are playable by standard media playback clients. The method is driven by a request for media content from a client, in response to which the server provides portions of the media content and monitors the reception rate of the content as it is sent to the client. This method allows for dynamic modification of the send rate of the content after the server has calculated an adjustment to correct for the difference between the reading rate and sending rate, thereby allowing for a send rate most compatible with the client.
摘要翻译：系统和方法提供了基于客户系统对先前发送的数据的检测到的读取速率来发送给客户端的内容的发送速率的即时适配。系统和方法在简单，现有，开放协议的范围内工作，并且提供的媒体文件可以由标准媒体播放客户端播放。该方法由来自客户端的对媒体内容的请求驱动，响应于此，服务器提供媒体内容的一部分，并且当它发送给客户端时监视内容的接收速率。该方法允许在服务器计算了调整以校正读取速率和发送速率之间的差异的情况下动态修改内容的发送速率，从而允许与客户端最相容的发送速率。

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