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11. 发明申请

US20120078096A1 APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS 有权
公开(公告)号：US20120078096A1
公开(公告)日：2012-03-29
申请号：US13216208
申请日：2011-08-23
申请人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
发明人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
IPC分类号： A61M25/10 , A61B6/00 , A61M1/00
CPC分类号： A61B17/22032 , A61B5/6853 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/22084 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M5/007 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/10185 , A61M29/02 , A61M2025/0008 , A61M2025/105 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

12. 发明授权

US09101382B2 Apparatus and methods for treating obstructions within body lumens 有权
公开(公告)号：US09101382B2
公开(公告)日：2015-08-11
申请号：US13216208
申请日：2011-08-23
申请人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
发明人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
IPC分类号： A61M25/10 , A61B17/22 , A61M25/00 , A61B17/221 , A61F2/958 , A61M29/02 , A61B17/3205 , A61B17/3207
CPC分类号： A61B17/22032 , A61B5/6853 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/22084 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M5/007 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/10185 , A61M29/02 , A61M2025/0008 , A61M2025/105 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

13. 发明申请

US20120197193A1 APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS 有权
标题翻译：用于在体内治疗梗阻的装置和方法
公开(公告)号：US20120197193A1
公开(公告)日：2012-08-02
申请号：US13444739
申请日：2012-04-11
申请人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
发明人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
IPC分类号： A61M25/10
CPC分类号： A61B17/22032 , A61B5/6853 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/22084 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M5/007 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/10185 , A61M29/02 , A61M2025/0008 , A61M2025/105 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.
摘要翻译：提供了设备和方法，用于在医疗过程中将流体输送到体腔中。装置的远端可以被引入体腔，并且可以打开远端上的阀，以将流体通过第一腔输送到体腔，例如造影剂和/或其它诊断或治疗剂。可以关闭阀，并且可以在体腔内执行程序，例如使用在远端承载的治疗元件。例如，治疗元件可以包括当阀关闭时流体通过第一内腔输送时可膨胀的球囊。任选地，假体，能量源，药物平台等可以由球囊承载以用于处理体腔。在各种实施例中，阀可以位于治疗元件的近侧或远侧。

14. 发明申请

US20100286593A1 BALLOON CATHETER WITH CUTTING FEATURES AND METHODS FOR USE 审中-公开
标题翻译：具有切割特征的气泡导管和使用方法
公开(公告)号：US20100286593A1
公开(公告)日：2010-11-11
申请号：US12778056
申请日：2010-05-11
申请人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe
发明人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe
IPC分类号： A61B17/22 , B29C47/00
CPC分类号： A61B17/320725 , A61B2017/00557 , A61B2017/22061 , A61M25/10 , A61M2025/1086 , B29C49/04 , B29L2031/7542
摘要： Apparatus and methods are provided for treating a lesion within a body lumen using a catheter including a balloon on its distal end that includes a plurality of raised structures that extend outwardly from the balloon membrane. In one embodiment, the raised structures are provided in pairs that are spaced apart from one another about the circumference of the balloon, and each pair includes two raised structures that are spaced relatively closely together compared to the distance the two raised structures are spaced apart from adjacent pairs. Optionally, the membrane between the two raised structures of each pair may be relatively thinner than the membrane between spaced apart pairs such that the distance between the raised structures in each pair increases as the balloon is expanded within a lesion.
摘要翻译：提供了用于使用包括其远端上的气囊的导管来治疗体腔内的损伤的装置和方法，该导管包括从气囊膜向外延伸的多个凸起结构。在一个实施例中，凸起结构成对设置，围绕球囊的圆周彼此间隔开，并且每对包括与两个凸起结构间隔开的距离相对靠近地间隔开的两个凸起结构相邻对。任选地，每对的两个凸起结构之间的膜可以比间隔开的对之间的膜相对薄，使得当气囊在损伤内扩张时，每对中的凸起结构之间的距离增加。

15. 发明授权

US08926649B2 Apparatus and methods for treating obstructions within body lumens 有权
标题翻译：用于治疗体腔内障碍物的装置和方法
公开(公告)号：US08926649B2
公开(公告)日：2015-01-06
申请号：US13444739
申请日：2012-04-11
申请人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
发明人： Jeffrey A. Krolik , Juan Domingo , Gwendolyn Watanabe , Ray Betelia , Lucas Fernandez
IPC分类号： A61M25/10 , A61B17/22 , A61B17/221 , A61B17/3207 , A61F2/958 , A61M29/02 , A61B17/3205 , A61M25/00
CPC分类号： A61B17/22032 , A61B5/6853 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/320725 , A61B2017/22034 , A61B2017/22061 , A61B2017/22082 , A61B2017/22084 , A61B2017/2212 , A61B2017/2215 , A61F2/958 , A61M5/007 , A61M25/0075 , A61M25/0097 , A61M25/10 , A61M25/1002 , A61M25/1011 , A61M25/10185 , A61M29/02 , A61M2025/0008 , A61M2025/105 , A61M2025/1068 , A61M2025/1077 , A61M2025/1084 , A61M2025/1086 , A61M2025/109
摘要： Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.
摘要翻译：提供了设备和方法，用于在医疗过程中将流体输送到体腔中。装置的远端可以被引入体腔，并且可以打开远端上的阀，以将流体通过第一腔输送到体腔，例如造影剂和/或其它诊断或治疗剂。可以关闭阀，并且可以在体腔内执行程序，例如使用在远端承载的治疗元件。例如，治疗元件可以包括当阀关闭时流体通过第一内腔输送时可膨胀的球囊。任选地，假体，能量源，药物平台等可以由球囊承载以用于处理体腔。在各种实施例中，阀可以位于治疗元件的近侧或远侧。

16. 发明授权

US07985240B2 Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture 有权
标题翻译：闭塞成员和张紧器设备及其用于密封血管穿刺的方法
公开(公告)号：US07985240B2
公开(公告)日：2011-07-26
申请号：US11929762
申请日：2007-10-30
申请人： Celso J. Bagaoisan , Juan Domingo , Nicanor Domingo , Farhad Khosravi , Suresh S. Pai
发明人： Celso J. Bagaoisan , Juan Domingo , Nicanor Domingo , Farhad Khosravi , Suresh S. Pai
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00557 , A61B2017/00637 , A61B2017/0065 , A61M25/10182 , A61M25/10187 , A61M2025/0681
摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.
摘要翻译：用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。

17. 发明申请

US20100168789A1 APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：用于密封血管内窥镜的装置和方法
公开(公告)号：US20100168789A1
公开(公告)日：2010-07-01
申请号：US12617693
申请日：2009-11-12
申请人： Celso J. Bagaoisan , Juan Domingo , Sieu Duong
发明人： Celso J. Bagaoisan , Juan Domingo , Sieu Duong
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/0065 , A61B2017/00654 , A61B2017/00893 , A61B2017/00898 , A61B2090/034 , A61B2090/0811
摘要： An apparatus for sealing a puncture includes a cartridge, a pusher member, a sealant, and a tamping device on a proximal end of the cartridge. During use, the cartridge, sealant, and pusher member are advanced over a positioning member and into the puncture by advancing a cartridge hub carrying the tamping device. When further distal advancement of the cartridge is limited, the cartridge hub is further advanced, activating the tamping device, and causing the pusher member to advance relative to the sealant to compress the sealant within the puncture.
摘要翻译：用于密封穿刺的装置包括在药筒的近端上的药筒，推动器构件，密封剂和捣固装置。在使用期间，盒，密封剂和推动器构件通过推进承载捣固装置的盒毂而前进到定位构件并进入穿刺。当盒的进一步的远侧前进受到限制时，盒轮毂进一步前进，启动捣固装置，并且使推动器构件相对于密封剂前进以压缩穿刺内的密封剂。

18. 发明申请

US20080082122A1 APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：用于密封血管内窥镜的装置和方法
公开(公告)号：US20080082122A1
公开(公告)日：2008-04-03
申请号：US11854534
申请日：2007-09-12
申请人： Farhad Khosravi , Suresh Pai , Celso Bagaoisan , Scott Sershen , Marlon Moreno , Juan Domingo
发明人： Farhad Khosravi , Suresh Pai , Celso Bagaoisan , Scott Sershen , Marlon Moreno , Juan Domingo
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654
摘要： An apparatus for sealing a puncture through tissue to a vessel includes an elongate occlusion member including an expandable member, a cartridge carried on the occlusion member, and a sealant carried within the cartridge. The cartridge includes an outer member and a pusher member within the outer member. The sealant is disposed within the outer member adjacent the expandable member distal to the pusher member. During use, the occlusion member is introduced into a puncture until the expandable member and the sealant extend from the puncture into the vessel. The expandable member is expanded, and withdrawn until the expanded expandable member contacts the vessel wall, thereby withdrawing the sealant back into the puncture. The outer member is withdrawn to expose the sealant within the puncture, while the pusher member prevents removal of the sealant, and then the cartridge, occlusion member, and pusher member are successively removed.
摘要翻译：用于将通过组织的穿刺密封到容器的装置包括包括可扩张构件的细长阻塞构件，承载在闭塞构件上的药筒和在药筒内承载的密封剂。该盒在外部构件内包括外部构件和推动构件。密封剂设置在外部构件中，邻近可推动构件远离推动构件。在使用期间，将阻塞构件引入穿刺中，直到可膨胀构件和密封剂从穿刺件延伸到容器中。可膨胀构件被膨胀并且被抽出直到膨胀的可膨胀构件接触血管壁，从而将密封剂抽回到穿刺中。取出外部构件以在穿刺中露出密封剂，同时推动器构件防止密封剂的移除，然后连续地移除盒，遮挡构件和推动构件。

19. 发明申请

US20120310277A1 APPARATUS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：封装血管内窥镜的装置
公开(公告)号：US20120310277A1
公开(公告)日：2012-12-06
申请号：US13587788
申请日：2012-08-16
申请人： Farhad Khosravi , Suresh S. Pai , Celso J. Bagaoisan , Scott R. Sershen , Marlon Moreno , Juan Domingo
发明人： Farhad Khosravi , Suresh S. Pai , Celso J. Bagaoisan , Scott R. Sershen , Marlon Moreno , Juan Domingo
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654
摘要： An apparatus for sealing a puncture through a vessel wall including an elongate tubular body, a balloon carried by the body, an outer tubular member carried over the tubular body, and a sealant carried by the tubular body adjacent the balloon. Retracting the outer tubular member exposes the sealant.
摘要翻译：一种用于通过容器壁密封穿刺的装置，包括细长的管状体，由身体承载的球囊，承载在管状体上的外部管状构件以及邻近气囊的管状体承载的密封剂。缩回外管状构件露出密封剂。

20. 发明申请

US20120310276A1 METHODS FOR SEALING A VASCULAR PUNCTURE 有权
标题翻译：用于密封血管的方法
公开(公告)号：US20120310276A1
公开(公告)日：2012-12-06
申请号：US13587781
申请日：2012-08-16
申请人： Farhad Khosravi , Suresh S. Pai , Celso J. Bagaoisan , Scott R. Sershen , Marlon Moreno , Juan Domingo
发明人： Farhad Khosravi , Suresh S. Pai , Celso J. Bagaoisan , Scott R. Sershen , Marlon Moreno , Juan Domingo
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/0065 , A61B2017/00654
摘要： A method for sealing a puncture through a vessel wall using a sealing device including an elongate tubular body, a balloon carried by the body, an outer tubular member carried over the elongate tubular body, and a sealant carried by the elongate tubular body adjacent the balloon. Retracting the outer tubular member exposes the sealant.
摘要翻译：一种用于通过使用包括细长管状体的密封装置，由本体承载的气囊，承载在细长管状体上的外部管状构件以及由细长管状体承载在该气囊附近的密封剂的密封装置来密封通过血管壁的穿刺的方法。缩回外管状构件露出密封剂。

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