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11. 发明申请

US20120289546A1 MONOHYDROCHLORIDE SALT OF 1-[3-[3-(4-CHLOROPHENYL) PROPOXY]PROPYL]-PIPERIDINE 有权
标题翻译： 1- [3- [3-（4-氯苯基）丙氧基]丙氧基]丙酸的单盐酸盐
公开(公告)号：US20120289546A1
公开(公告)日：2012-11-15
申请号：US13491229
申请日：2012-06-07
申请人： Manuel RAGA , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
发明人： Manuel RAGA , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
IPC分类号： A61K31/4453 , A61P25/00
CPC分类号： C07D295/088
摘要： A method is provided for the treatment of sleep apnea and other conditions wherein an effective amount of crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride of formula (I): optionally comprising water up to 6%, and having an X-ray diffractogram that comprises characteristic peaks (2θ) at 11.2°, 19.9°, 20.7° and 34.1°±0.2° is administered to a patient in need thereof.
摘要翻译：提供了一种用于治疗睡眠呼吸暂停和其它病症的方法，其中有效量的结构式（I）的1- [3- [3-（4-氯苯基）丙氧基]丙基] - 哌啶一盐酸盐：任选地包含至多 6％，并且对于有需要的患者施用包含在11.2°，19.9°，20.7°和34.1°±0.2°的特征峰（2θ）的X射线衍射图。

12. 发明授权

US08207197B2 Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl) propoxy] propyl] -piperidine 有权
标题翻译： 1- [3- [3-（4-氯苯基）丙氧基]丙基] - 哌啶的单盐酸盐
公开(公告)号：US08207197B2
公开(公告)日：2012-06-26
申请号：US11815736
申请日：2006-02-06
申请人： Manuel Raga , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
发明人： Manuel Raga , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
IPC分类号： A61K31/4453 , C07D295/088
CPC分类号： C07D295/088
摘要： The invention relates to new crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride, the respective manufacture and methods of use, and compositions containing such a compound.
摘要翻译：本发明涉及新的结晶1- [3- [3-（4-氯苯基）丙氧基]丙基] - 哌啶一盐酸盐，各自的制造和使用方法以及含有这种化合物的组合物。

13. 发明授权

US07941922B2 Method of manufacturing a lightweight valve 失效
标题翻译：制造轻型阀门的方法
公开(公告)号：US07941922B2
公开(公告)日：2011-05-17
申请号：US10579887
申请日：2004-11-06
申请人： Holger Stark , Martin Schlegl
发明人： Holger Stark , Martin Schlegl
IPC分类号： B21K1/20
CPC分类号： F01L3/20 , Y10T29/49307 , Y10T29/49314 , Y10T29/49412
摘要： A method for manufacturing a lightweight valve is provided. The lightweight valve includes a valve stem, a hollow valve cone and a valve disk closing the valve cone, the valve stem being provided with a hollow space at an end facing the valve disk, the valve disk also having a force transmission element extending through the hollow valve cone into the stem hollow space. The method includes producing a first one-piece component forming the valve disk with the force transmission element by casting, forming and/or a powder metallurgy method, producing a second component forming the valve stem and the valve cone and joining the first and second components together and connecting them by a material, non-positive and/or positive connection.
摘要翻译：提供了一种制造轻型阀的方法。轻型阀包括阀杆，中空阀锥和闭合阀锥的阀盘，阀杆在面向阀盘的端部处设置有中空空间，阀盘还具有延伸穿过阀芯的力传递元件中空阀锥进入中空空间。该方法包括通过铸造，成形和/或粉末冶金法制造形成具有力传递元件的阀盘的第一单件部件，形成形成阀杆和阀锥并且将第一和第二部件在一起并通过物质，非积极和/或积极的联系连接它们。

14. 发明申请

US20090114192A1 Injector for accumulator injector system 审中-公开
标题翻译：蓄能注射器系统注射器
公开(公告)号：US20090114192A1
公开(公告)日：2009-05-07
申请号：US12284149
申请日：2008-09-18
申请人： Stefan Espig , Bernhard Jutz , Johannes Leweux , Gregor Renner , Heiko Sass , Nicole Schlegl , Holger Stark , Thomas Stolk , Andreas Vortmeier
发明人： Stefan Espig , Bernhard Jutz , Johannes Leweux , Gregor Renner , Heiko Sass , Nicole Schlegl , Holger Stark , Thomas Stolk , Andreas Vortmeier
IPC分类号： F02M63/00
CPC分类号： F02M51/0603 , F02M63/0225
摘要： In an injector for an accumulator injection system comprising an injector having an injector housing with an injection nozzle and an actuator for operating the injection nozzle arranged in a fuel-filled pressure space of the injector housing wherein the actuator includes a piezoelectric element disposed between an actuator head and an actuator the base with a fuel-tight casing at least partially surrounding the actuator head and the actuator base, the casing is engaged in a sealing fashion by a first annular element with the actuator base and by a second annular element with the actuator head.
摘要翻译：在一种用于蓄能器注射系统的注射器中，该注射器包括具有喷射器壳体和喷射器的喷射器，以及用于操作设置在喷射器壳体的燃料填充的压力空间中的喷射喷嘴的致动器，其中致动器包括设置在致动器头部和致动器，具有至少部分地围绕致动器头部和致动器基座的燃料密封壳体的基座，壳体以密封方式与第一环形元件与致动器基座接合，并且通过第二环形元件与致动器接合头。

15. 发明申请

US20070266984A1 Lightweight Valve 审中-公开
标题翻译：轻便阀门
公开(公告)号：US20070266984A1
公开(公告)日：2007-11-22
申请号：US10579285
申请日：2004-11-09
申请人： Rudolf Reinhardt , Martin Schlegl , Holger Stark
发明人： Rudolf Reinhardt , Martin Schlegl , Holger Stark
IPC分类号： F01L3/20
CPC分类号： F01L3/20
摘要： A lightweight valve (1), in particular for internal combustion engines, is provided, with a valve stem (3), with a hollow valve cone (5) and with a valve disk (7) closing the valve cone (5), the valve disk (7) being provided with a recess (23) on its flat side facing the valve cone (5). The lightweight valve (1) has a valve cone (5) projecting with its end region of greater diameter into the recess (23).
摘要翻译：提供了一种特别用于内燃机的轻质阀（1），具有阀杆（3），带有中空阀锥（5）和与关闭阀锥（5）的阀盘（7），阀盘（7）在其与阀锥（5）相对的平坦侧上设置有凹部（23）。轻型阀（1）具有一个其锥形突出部（5），其端部区域具有较大直径的凹槽（23）。

16. 发明授权

US07862007B2 Lightweight valve 失效
标题翻译：轻便阀
公开(公告)号：US07862007B2
公开(公告)日：2011-01-04
申请号：US10579284
申请日：2004-11-04
申请人： Martin Schlegl , Holger Stark
发明人： Martin Schlegl , Holger Stark
IPC分类号： B22D41/16
CPC分类号： F01L3/20
摘要： A lightweight valve (1), in particular for internal combustion engines, is provided, with a valve stem (3), with a hollow valve cone (5) and with a valve disk (7) closing the valve cone hollow space on one side, a valve cone support being provided in the hollow space. The valve cone support is provided at a distance from the valve disk (7).
摘要翻译：提供了一种特别用于内燃机的轻质阀（1），其具有带有中空阀锥（5）的阀杆（3）和一个在一侧封闭阀锥空心空间的阀盘（7）在中空空间中设置有阀锥支架。阀瓣支撑件设置在与阀盘（7）一定距离处。

17. 发明申请

US20080272325A1 Lightweight Valve 失效
标题翻译：轻便阀门
公开(公告)号：US20080272325A1
公开(公告)日：2008-11-06
申请号：US10579284
申请日：2004-11-04
申请人： Martin Schlegl , Holger Stark
发明人： Martin Schlegl , Holger Stark
IPC分类号： F16K1/00
CPC分类号： F01L3/20
摘要： A lightweight valve (1), in particular for internal combustion engines, is provided, with a valve stem (3), with a hollow valve cone (5) and with a valve disk (7) closing the valve cone hollow space on one side, a valve cone support being provided in the hollow space. The valve cone support is provided at a distance from the valve disk (7).
摘要翻译：提供了一种特别用于内燃机的轻质阀（1），其具有带有中空阀锥（5）的阀杆（3）和一个在一侧封闭阀锥空心空间的阀盘（7）在中空空间中设置有阀锥支架。阀瓣支撑件设置在与阀盘（7）一定距离处。

18. 发明申请

US20060222503A1 Compressor and turbine wheel for a secondary air feed device 有权
标题翻译：用于二次空气供给装置的压缩机和涡轮机叶轮
公开(公告)号：US20060222503A1
公开(公告)日：2006-10-05
申请号：US11399686
申请日：2006-04-06
申请人： Peter Fledersbacher , Hans-Georg Lehmann , Martin Schlegl , Holger Stark
发明人： Peter Fledersbacher , Hans-Georg Lehmann , Martin Schlegl , Holger Stark
IPC分类号： F01D5/14
CPC分类号： F04D25/045 , F01D15/08 , F01N3/32 , Y02T10/20
摘要： In a compressor and turbine wheel for a secondary air feed device formed as a single component, a rotor which includes a center disc structure consisting of at least two discs of different materials is provided at one side with compressor blades and on the opposite side with turbine blades, and the discs consist of an alloy based on Al, Mg, Ti, Fe, or Ni and are preferably arranged in axially spaced relationship with a disc carrier of a plastic material disposed in the space between the two bladed discs.
摘要翻译：在形成为单个部件的二次空气供给装置的压缩机和涡轮机叶轮中，包括由至少两个不同材料的盘构成的中心盘结构的转子在一侧设置有压缩机叶片，并且在与涡轮相反的一侧叶片，并且盘由基于Al，Mg，Ti，Fe或Ni的合金组成，并且优选地与设置在两个叶片盘之间的空间中的塑料材料的盘式载体轴向间隔开地布置。

19. 发明授权

US08389555B2 Medicaments 有权
标题翻译：药剂
公开(公告)号：US08389555B2
公开(公告)日：2013-03-05
申请号：US12740147
申请日：2008-10-28
申请人： Holger Stark , Jukka Matti Leppanen , Britta Caroline Sasse , Oliver Saur , Tim Kottke , Michael Peter Hill
发明人： Holger Stark , Jukka Matti Leppanen , Britta Caroline Sasse , Oliver Saur , Tim Kottke , Michael Peter Hill
IPC分类号： A61K31/425 , C07D277/60 , C07D277/62
CPC分类号： C07D277/60 , C07D277/82 , C07D417/12
摘要： A compound of formal (I) is described: wherein R1 and R2 are as defined in the text and wherein the compounds are intended for use in treating medical conditions characterized by an imbalance in dopamine receptor activity.
摘要翻译：描述了形式（I）的化合物：其中R1和R2如本文中所定义，并且其中所述化合物旨在用于治疗以多巴胺受体活性不平衡为特征的医学病症。

20. 发明申请

US20130029236A1 Device for Providing Hot Exhaust Gases 审中-公开
标题翻译：提供热排气的装置
公开(公告)号：US20130029236A1
公开(公告)日：2013-01-31
申请号：US13582690
申请日：2010-12-04
申请人： Holger Stark , Ulf-Michael Mex , Gerhard Konrad , Benjamin Steinhauser , Gert Hinsenkamp
发明人： Holger Stark , Ulf-Michael Mex , Gerhard Konrad , Benjamin Steinhauser , Gert Hinsenkamp
IPC分类号： F23R3/40 , H01M8/06 , F02C7/266
CPC分类号： F23R3/40 , F23C99/006
摘要： A device used to provide hot exhaust gases for driving a turbine. The device includes a burner, the combustion zone of which is directly mounted on or integrated into the gas inlet (turbine housing) of the turbine. The burner is supplied with at least one combustible gas or gas mixture. The combustion zone includes a porous material with a large specific surface area.
摘要翻译：用于提供用于驱动涡轮机的热废气的装置。该装置包括燃烧器，其燃烧区域直接安装在涡轮机的气体入口（涡轮机壳体）上或集成在其中。燃烧器供应至少一种可燃气体或气体混合物。燃烧区包括具有大比表面积的多孔材料。

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