专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US5315610A System for controlling the flow of gas into and out of a gas laser 失效
标题翻译：用于控制气体流入和流出气体激光器的系统
公开(公告)号：US5315610A
公开(公告)日：1994-05-24
申请号：US911189
申请日：1986-09-22
申请人： Terry Alger , Dennis M. Uhlich , William J. Benett , Earl R. Ault
发明人： Terry Alger , Dennis M. Uhlich , William J. Benett , Earl R. Ault
IPC分类号： H01S3/036 , H01S3/00
CPC分类号： H01S3/036
摘要： A modularized system for controlling the gas pressure within a copper vapor or like laser is described herein. This system includes a gas input assembly which serves to direct gas into the laser in a controlled manner in response to the pressure therein for maintaining the laser pressure at a particular value, for example 40 torr. The system also includes a gas output assembly including a vacuum pump and a capillary tube arrangement which operates within both a viscous flow region and a molecular flow region for drawing gas out of the laser in a controlled manner.
摘要翻译：本文描述了用于控制铜蒸汽或类似激光器内的气体压力的模块化系统。该系统包括气体输入组件，其用于响应于其中的压力以受控的方式将气体引导到激光器中，以将激光压力保持在特定值，例如40托。该系统还包括气体输出组件，其包括真空泵和毛细管装置，其在粘性流动区域和分子流动区域内操作，用于以受控的方式将气体引出激光器。

12. 发明授权

US10010327B2 Expandable implant and implant system 有权
公开(公告)号：US10010327B2
公开(公告)日：2018-07-03
申请号：US13325906
申请日：2011-12-14
申请人： Thomas S. Wilson , Ward Small, IV , William J. Benett , Jason M. Ortega , Duncan J. Maitland , Jonathan Hartman
发明人： Thomas S. Wilson , Ward Small, IV , William J. Benett , Jason M. Ortega , Duncan J. Maitland , Jonathan Hartman
IPC分类号： A61B17/03 , A61B17/12 , A61M25/06 , A61M25/00 , A61B17/00
CPC分类号： A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12181 , A61B2017/00871 , A61B2017/12054 , A61M25/0668 , A61M2025/0042
摘要： An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.

13. 发明授权

US08778663B2 Thermal cycler 有权
标题翻译：热循环仪
公开(公告)号：US08778663B2
公开(公告)日：2014-07-15
申请号：US11901787
申请日：2007-09-18
申请人： William J. Benett , John T. Andreski , John M. Dzenitis , Anthony J. Makarewicz , Dean R. Hadley , Satinderpall S. Pannu
发明人： William J. Benett , John T. Andreski , John M. Dzenitis , Anthony J. Makarewicz , Dean R. Hadley , Satinderpall S. Pannu
IPC分类号： C12M1/00 , C12M3/00 , B01L7/00 , C12Q1/68 , B01L3/00
CPC分类号： B01L7/52 , B01L3/50851 , B01L7/525 , B01L2200/02 , B01L2200/147 , B01L2300/1805 , B01L2300/1827 , C12M41/14 , C12Q1/6844 , Y10T29/4935
摘要： A thermalcycler includes a first thermalcycler body section having a first face and a second thermalcycler body section having a second face. A cavity is formed by the first face and the second face. A thermalcycling unit is positioned in the cavity. A heater trace unit is connected to a support section, to the first thermalcycler body section, to the second thermalcycler body section, and to the thermalcycling unit. The first thermalcycler body section and the second thermalcycler body section are positioned together against the support section to enclose the thermalcycling unit and the heater trace unit.
摘要翻译：热循环器包括具有第一面的第一热循环器主体部分和具有第二面的第二热循环器主体部分。空腔由第一面和第二面形成。热循环装置位于空腔中。加热器跟踪单元连接到支撑部分，连接到第一热循环器主体部分，连接到第二热循环器主体部分，并连接到热循环单元。第一热循环器主体部分和第二热循环器主体部分一起被放置在支撑部分上以包围热循环单元和加热器跟踪单元。

14. 发明授权

US07578976B1 Sleeve reaction chamber system 失效
标题翻译：套筒反应室系统
公开(公告)号：US07578976B1
公开(公告)日：2009-08-25
申请号：US09568618
申请日：2000-05-10
申请人： M. Allen Northrup , Barton V. Beeman , William J. Benett , Dean R. Hadley , Phoebe Landre , Stacy L. Lehew , Peter A. Krulevitch
发明人： M. Allen Northrup , Barton V. Beeman , William J. Benett , Dean R. Hadley , Phoebe Landre , Stacy L. Lehew , Peter A. Krulevitch
IPC分类号： G01N33/00
CPC分类号： B01L7/52 , B01L2300/0838 , B01L2300/1822
摘要： A chemical reaction chamber system that combines devices such as doped polysilicon for heating, bulk silicon for convective cooling, and thermoelectric (TE) coolers to augment the heating and cooling rates of the reaction chamber or chambers. In addition the system includes non-silicon-based reaction chambers such as any high thermal conductivity material used in combination with a thermoelectric cooling mechanism (i.e., Peltier device). The heat contained in the thermally conductive part of the system can be used/reused to heat the device, thereby conserving energy and expediting the heating/cooling rates. The system combines a micromachined silicon reaction chamber, for example, with an additional module/device for augmented heating/cooling using the Peltier effect. This additional module is particularly useful in extreme environments (very hot or extremely cold) where augmented heating/cooling would be useful to speed up the thermal cycling rates. The chemical reaction chamber system has various applications for synthesis or processing of organic, inorganic, or biochemical reactions, including the polymerase chain reaction (PCR) and/or other DNA reactions, such as the ligase chain reaction.
摘要翻译：化学反应室系统，其组合诸如用于加热的掺杂多晶硅，对流冷却的散装硅和热电（TE）冷却器的装置，以增加反应室或室的加热和冷却速率。此外，该系统包括非硅基反应室，例如与热电冷却机构（即珀尔帖装置）结合使用的任何高导热性材料。系统的导热部分中所含的热量可以用于/再利用来加热装置，从而节省能量并加快加热/冷却速度。该系统将微加工硅反应室与例如使用珀尔帖效应进行增强加热/冷却的附加模块/装置相结合。该额外的模块在极端环境（非常热或极冷）中特别有用，其中增强的加热/冷却将有助于加快热循环速率。化学反应室系统具有用于合成或加工有机，无机或生化反应的各种应用，包括聚合酶链式反应（PCR）和/或其他DNA反应，如连接酶链式反应。

15. 发明授权

US06699713B2 Polymerase chain reaction system 有权
标题翻译：聚合酶链反应体系
公开(公告)号：US06699713B2
公开(公告)日：2004-03-02
申请号：US09752794
申请日：2000-12-29
申请人： William J. Benett , James B. Richards , Paul L. Stratton , Dean R. Hadley , Fred P. Milanovich , Phil Belgrader , Peter L. Meyer
发明人： William J. Benett , James B. Richards , Paul L. Stratton , Dean R. Hadley , Fred P. Milanovich , Phil Belgrader , Peter L. Meyer
IPC分类号： C12M134
CPC分类号： C12M1/34 , B01L7/52
摘要： A portable polymerase chain reaction DNA amplification and detection system includes one or more chamber modules. Each module supports a duplex assay of a biological sample. Each module has two parallel interrogation ports with a linear optical system. The system is capable of being handheld.
摘要翻译：便携式聚合酶链反应DNA扩增和检测系统包括一个或多个室模块。每个模块支持生物样品的双相测定。每个模块具有两个具有线性光学系统的并行询问端口。该系统能够被手持。

16. 发明授权

US06575965B1 Medical devices utilizing optical fibers for simultaneous power, communications and control 有权
标题翻译：利用光纤同时进行电力，通信和控制的医疗设备
公开(公告)号：US06575965B1
公开(公告)日：2003-06-10
申请号：US09713988
申请日：2000-11-16
申请人： Joseph P. Fitch , Dennis L. Matthews , Karla G. Hagans , Abraham P. Lee , Peter Krulevitch , William J. Benett , Robert E. Clough , Luiz B. DaSilva , Peter M. Celliers
发明人： Joseph P. Fitch , Dennis L. Matthews , Karla G. Hagans , Abraham P. Lee , Peter Krulevitch , William J. Benett , Robert E. Clough , Luiz B. DaSilva , Peter M. Celliers
IPC分类号： A61B1822
CPC分类号： A61B17/12022 , A61B5/0084 , A61B17/1214 , A61B17/29 , A61B2017/00292 , A61B2017/00345 , A61B2017/12072 , A61B2017/12077 , A61B2017/2926
摘要： A medical device is constructed in the basic form of a catheter having a distal end for insertion into and manipulation within a body and a proximal end providing for a user to control the manipulation of the distal end within the body. A fiberoptic cable is disposed within the catheter and having a distal end proximate to the distal end of the catheter and a proximal end for external coupling of laser light energy. A laser-light-to-mechanical-power converter is connected to receive light from the distal end of the fiber optic cable and may include a photo-voltaic cell and an electromechanical motor or a heat-sensitive photo-thermal material. An electronic sensor is connected to receive electrical power from said distal end of the fiberoptic cable and is connected to provide signal information about a particular physical environment and communicated externally through the fiberoptic cable to the proximal end thereof. A mechanical sensor is attached to the distal end of the fiberoptic cable and connected to provide light signal information about a particular physical environment and communicated externally through the fiberoptic cable.
摘要翻译：医疗装置构造成具有导管的基本形式，其具有用于插入体内和在体内操作的远端，并且近端为使用者提供控制体内远端的操作。光纤电缆设置在导管内并且具有靠近导管远端的远端和用于激光光能的外部耦合的近端。连接激光 - 光机械功率转换器以接收来自光纤电缆的远端的光，并且可以包括光电池和机电马达或热敏光热材料。电子传感器被连接以从光纤电缆的所述远端接收电力，并且被连接以提供关于特定物理环境的信号信息，并且通过光纤电缆向外传播到其近端。机械传感器连接到光纤电缆的远端并被连接以提供关于特定物理环境的光信号信息，并通过光纤电缆在外部通信。

17. 发明授权

US06491685B2 Laser and acoustic lens for lithotripsy 失效
标题翻译：激光和声透镜用于碎石术
公开(公告)号：US06491685B2
公开(公告)日：2002-12-10
申请号：US09516999
申请日：2000-03-01
申请人： Steven R. Visuri , Anthony J. Makarewicz , Richard A. London , William J. Benett , Peter Krulevitch , Luiz B. Da Silva
发明人： Steven R. Visuri , Anthony J. Makarewicz , Richard A. London , William J. Benett , Peter Krulevitch , Luiz B. Da Silva
IPC分类号： A61B1722
CPC分类号： A61B18/26 , A61B2018/263
摘要： An acoustic focusing device whose acoustic waves are generated by laser radiation through an optical fiber. The acoustic energy is capable of efficient destruction of renal and biliary calculi and deliverable to the site of the calculi via an endoscopic procedure. The device includes a transducer tip attached to the distal end of an optical fiber through which laser energy is directed. The transducer tip encapsulates an exogenous absorbing dye. Under proper irradiation conditions (high absorbed energy density, short pulse duration) a stress wave is produced via thermoelastic expansion of the absorber for the destruction of the calculi. The transducer tip can be configured into an acoustic lens such that the transmitted acoustic wave is shaped or focused. Also, compressive stress waves can be reflected off a high density/low density interface to invert the compressive wave into a tensile stress wave, and tensile stresses may be more effective in some instances in disrupting material as most materials are weaker in tension than compression. Estimations indicate that stress amplitudes provided by this device can be magnified more than 100 times, greatly improving the efficiency of optical energy for targeted material destruction.
摘要翻译：声波聚焦装置，其声波通过激光辐射通过光纤产生。声能能够有效地破坏肾脏和胆汁结石，并可通过内窥镜手术递送至结石部位。该装置包括附接到光纤的远端的换能器尖端，通过激光能量被引导。换能器尖端封装外源吸收染料。在适当的照射条件（高吸收能量密度，短脉冲持续时间）下，通过吸收器的热弹性膨胀产生应力波，以破坏结石。换能器尖端可以被配置成声透镜，使得发射的声波成形或聚焦。此外，压应力波可以从高密度/低密度界面反射，以将压缩波反转成拉伸应力波，并且拉伸应力在某些情况下在破坏材料中可能更有效，因为大多数材料的张力比压缩弱。估计表明，该装置提供的应力幅度可以放大100倍以上，大大提高了光能量对目标材料的破坏效率。

18. 发明授权

US06273478B1 Microfluidic interconnects 失效
标题翻译：微流控互连
公开(公告)号：US06273478B1
公开(公告)日：2001-08-14
申请号：US09281345
申请日：1999-03-30
申请人： William J. Benett , Peter A. Krulevitch
发明人： William J. Benett , Peter A. Krulevitch
IPC分类号： F16L2103
CPC分类号： F16L19/0218 , F15C5/00 , F16L21/03
摘要： A miniature connector for introducing microliter quantities of solutions into microfabricated fluidic devices, and which incorporates a molded ring or seal set into a ferrule cartridge, with or without a compression screw. The fluidic connector, for example, joins standard high pressure liquid chromatography (HPLC) tubing to 1 mm diameter holes in silicon or glass, enabling ml-sized volumes of sample solutions to be merged with &mgr;l-sized devices. The connector has many features, including ease of connect and disconnect; a small footprint which enables numerous connectors to be located in a small area; low dead volume; helium leak-tight; and tubing does not twist during connection. Thus the connector enables easy and effective change of microfluidic devices and introduction of different solutions in the devices.
摘要翻译：一种微型连接器，用于将微量的溶液引入微细加工的流体装置中，并且将带有或不带有压缩螺杆的模制环或密封件组合到套圈盒中。例如，流体连接器将标准高压液相色谱（HPLC）管道连接到硅或玻璃中的1mm直径的孔中，使得能够将大小体积的样品溶液与多种尺寸的装置合并。连接器具有许多功能，包括易于连接和断开连接; 小的占地面积，使许多连接器位于一个小区域; 死亡体积小氦密封; 并且管道在连接期间不扭曲。因此，连接器能够简单有效地改变微流体装置并在装置中引入不同的解决方案。

19. 发明授权

US06240630B1 Apparatus for loading shape memory gripper mechanisms 失效
标题翻译：装载形状记忆夹持机构的装置
公开(公告)号：US06240630B1
公开(公告)日：2001-06-05
申请号：US08984624
申请日：1997-12-03
申请人： Abraham P. Lee , William J. Benett , Daniel L. Schumann , Peter A. Krulevitch , Joseph P. Fitch
发明人： Abraham P. Lee , William J. Benett , Daniel L. Schumann , Peter A. Krulevitch , Joseph P. Fitch
IPC分类号： B21D3904
CPC分类号： A61B17/221 , A61B17/1219 , A61B2017/00345 , A61B2017/00867 , A61B2017/00871 , A61B2017/1205 , A61B2017/12068 , A61B2017/12072 , Y10T29/49865 , Y10T29/49929 , Y10T29/53439 , Y10T29/53987
摘要： A method and apparatus for loading deposit material, such as an embolic coil, into a shape memory polymer (SMP) gripping/release mechanism. The apparatus enables the application of uniform pressure to secure a grip by the SMP mechanism on the deposit material via differential pressure between, for example, vacuum within the SMP mechanism and hydrostatic water pressure on the exterior of the SMP mechanism. The SMP tubing material of the mechanism is heated to above the glass transformation temperature (Tg) while reshaping, and subsequently cooled to below Tg to freeze the shape. The heating and/or cooling may, for example, be provided by the same water applied for pressurization or the heating can be applied by optical fibers packaged to the SMP mechanism for directing a laser beam, for example, thereunto. At a point of use, the deposit material is released from the SMP mechanism by reheating the SMP material to above the temperature Tg whereby it returns to its initial shape. The reheating of the SM material may be carried out by injecting heated fluid (water) through an associated catheter or by optical fibers and an associated beam of laser light, for example.
摘要翻译：一种用于将诸如栓塞线圈的沉积材料装载到形状记忆聚合物（SMP）夹持/释放机构中的方法和装置。该装置能够通过例如SMP机构中的真空和SMP机构的外部上的静水压力之间的压差来施加均匀的压力，以通过SMP机构来确保在沉积材料上的握持。将机构的SMP管材料加热至高于玻璃化转变温度（Tg），同时重塑，随后冷却至Tg以下以冻结形状。加热和/或冷却可以例如由施加加压的相同的水提供，或者可以通过包封在SMP机构中的光纤施加加热，以引导例如激光束。在使用时，通过将SMP材料再加热到高于Tg的温度Tg，沉积材料从SMP机制释放，由此其恢复到初始形状。 SM材料的再加热可以通过例如通过相关联的导管或通过光纤和相关的激光束注入加热的流体（水）来进行。

20. 发明授权

US06209928B1 Microfluidic interconnects 失效
标题翻译：微流控互连
公开(公告)号：US06209928B1
公开(公告)日：2001-04-03
申请号：US09090769
申请日：1998-06-04
申请人： William J. Benett , Peter A. Krulevitch
发明人： William J. Benett , Peter A. Krulevitch
IPC分类号： F16L3900
CPC分类号： F16L37/025
摘要： A miniature connector for introducing microliter quantities of solutions into microfabricated fluidic devices. The fluidic connector, for example, joins standard high pressure liquid chromatography (HPLC) tubing to 1 mm diameter holes in silicon or glass, enabling ml-sized volumes of sample solutions to be merged with &mgr;l-sized devices. The connector has many features, including ease of connect and disconnect; a small footprint which enables numerous connectors to be located in a small area; low dead volume; helium leak-tight; and tubing does not twist during connection. Thus the connector enables easy and effective change of microfluidic devices and introduction of different solutions in the devices.
摘要翻译：用于将微量数量的溶液引入微制造流体装置的微型连接器。例如，流体连接器将标准高压液相色谱（HPLC）管道连接到硅或玻璃中的1mm直径的孔中，使得能够将大小体积的样品溶液与多种尺寸的装置合并。连接器具有许多功能，包括易于连接和断开连接; 小的占地面积，使许多连接器位于一个小区域; 死亡体积小氦密封; 并且管道在连接期间不扭曲。因此，连接器能够简单有效地改变微流体装置并在装置中引入不同的解决方案。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式