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11. 发明申请

US20210110419A1 SYSTEMS AND METHODS FOR MANAGEMENT OF THROMBOSIS 有权
公开(公告)号：US20210110419A1
公开(公告)日：2021-04-15
申请号：US17130586
申请日：2020-12-22
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： G06Q30/02 , A61B17/22 , A61B17/3203 , A61M1/00 , G06Q30/06
摘要： An aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.

12. 发明授权

US10702292B2 Aspiration monitoring system and method 有权
公开(公告)号：US10702292B2
公开(公告)日：2020-07-07
申请号：US15245124
申请日：2016-08-23
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61M31/00 , A61M1/00 , A61B17/22 , A61M25/00 , A61M27/00 , A61B17/00 , A61B90/00
摘要： A system for real time monitoring of catheter aspiration includes a pressure sensor configured for placement in fluid communication with a lumen which at least partially includes an aspiration lumen of a catheter, the aspiration lumen configured to couple to a vacuum source, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate a continuous signal which is proportional to measured fluid pressure.

13. 发明申请

US20190328410A1 SYSTEMS AND METHODS FOR MANAGEMENT OF THROMBOSIS 审中-公开
公开(公告)号：US20190328410A1
公开(公告)日：2019-10-31
申请号：US16504768
申请日：2019-07-08
申请人： INCUVATE, LLC
发明人： DAVID M. Look , Bradley S. Culbert
IPC分类号： A61B17/22
摘要： An aspiration system includes an aspiration catheter including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of an elongate tubular member and into the vasculature of a subject, an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, a high pressure injection lumen extending within the elongate support member and having a distal end including a curved portion configured to change a direction of fluid flow by at least about 90°, at least one orifice located at the distal end of the high pressure injection lumen configured to allow liquid to be released into the lumen of the tubular aspiration member, and an annular seal carried by the tubular aspiration member and configured to create a liquid seal against the inner surface of the elongate tubular member.

14. 发明授权

US10192230B2 Systems and methods for management of thrombosis 有权
公开(公告)号：US10192230B2
公开(公告)日：2019-01-29
申请号：US15881529
申请日：2018-01-26
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61B17/22 , G06Q30/02 , A61M1/00 , A61B17/3203 , G06Q30/06 , A61B17/00
摘要： An aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.

15. 发明授权

US09913936B2 Systems and methods for management of thrombosis 有权
公开(公告)号：US09913936B2
公开(公告)日：2018-03-13
申请号：US15209989
申请日：2016-07-14
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61B17/22 , A61M1/00 , A61B17/3203 , A61B17/00
CPC分类号： G06Q30/0207 , A61B17/22 , A61B17/32037 , A61B2017/00022 , A61B2017/00119 , A61B2017/22001 , A61B2017/22039 , A61B2017/22067 , A61B2017/22079 , A61B2017/22094 , A61B2217/005 , A61M1/0088 , G06Q30/02 , G06Q30/0601
摘要： A method for aspirating material from a patient includes providing an elongate tubular member having a lumen having a first diameter adjacent its distal end, providing an aspiration catheter including a tubular aspiration member having an aspiration lumen and configured to at least partially extend out of the lumen of the elongate tubular member, an elongate support member coupled to the tubular aspiration member, and at least one annular sealing member coupled to the tubular aspiration member and configured to seal against the first diameter, placing the distal end of the elongate tubular member into vasculature, inserting the aspiration catheter into the lumen of the elongate tubular member, extending the distal end of the tubular aspiration member out of the distal end of the elongate tubular member such that the at least one annular sealing member is aligned with the first diameter of the lumen of the elongate tubular member, and applying a vacuum to the lumen of the elongate tubular member at the such that material is aspirated through the tubular aspiration member and into the lumen of the elongate tubular member.

16. 发明申请

US20160317726A1 SYSTEMS AND METHODS FOR MANAGEMENT OF THROMBOSIS 审中-公开
标题翻译：用于管理血栓形成的系统和方法
公开(公告)号：US20160317726A1
公开(公告)日：2016-11-03
申请号：US15209989
申请日：2016-07-14
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61M1/00
CPC分类号： G06Q30/0207 , A61B17/22 , A61B17/32037 , A61B2017/00022 , A61B2017/00119 , A61B2017/22001 , A61B2017/22039 , A61B2017/22067 , A61B2017/22079 , A61B2017/22094 , A61B2217/005 , A61M1/0088 , G06Q30/02 , G06Q30/0601
摘要： A method for aspirating material from a patient includes providing an elongate tubular member having a lumen having a first diameter adjacent its distal end, providing an aspiration catheter including a tubular aspiration member having an aspiration lumen and configured to at least partially extend out of the lumen of the elongate tubular member, an elongate support member coupled to the tubular aspiration member, and at least one annular sealing member coupled to the tubular aspiration member and configured to seal against the first diameter, placing the distal end of the elongate tubular member into vasculature, inserting the aspiration catheter into the lumen of the elongate tubular member, extending the distal end of the tubular aspiration member out of the distal end of the elongate tubular member such that the at least one annular sealing member is aligned with the first diameter of the lumen of the elongate tubular member, and applying a vacuum to the lumen of the elongate tubular member at the such that material is aspirated through the tubular aspiration member and into the lumen of the elongate tubular member.
摘要翻译：用于从患者吸出材料的方法包括提供细长管状构件，其具有邻近其远端的具有第一直径的内腔，提供吸入导管，其包括管状抽吸构件，其具有抽吸腔并构造成至少部分地延伸出管腔细长管状构件的细长支撑构件，以及联接到管状抽吸构件的细长支撑构件，以及联接到管状抽吸构件并被配置为密封抵靠第一直径的至少一个环形密封构件，将细长管状构件的远端放置成脉管系统将吸入导管插入细长管状构件的内腔中，将管状抽吸构件的远端从细长管状构件的远端延伸出来，使得至少一个环形密封构件与第一直径对准细长管状构件的腔，以及对细管的内腔施加真空以使得材料通过管状抽吸构件被吸入并进入细长管状构件的内腔。

17. 发明授权

US11678896B2 Aspiration monitoring system and method 有权
公开(公告)号：US11678896B2
公开(公告)日：2023-06-20
申请号：US16792817
申请日：2020-02-17
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61B17/22 , A61M1/00 , A61B17/00
CPC分类号： A61B17/22 , A61M1/732 , A61M1/74 , A61M1/84 , A61B2017/00119 , A61B2017/00221 , A61B2217/005 , A61M2205/15 , A61M2205/18 , A61M2205/3327 , A61M2205/3331 , A61M2205/3355 , A61M2205/50 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.

18. 发明授权

US11051832B2 Aspiration monitoring system and method 有权
公开(公告)号：US11051832B2
公开(公告)日：2021-07-06
申请号：US16239679
申请日：2019-01-04
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61B17/221 , A61B17/22 , A61M1/00 , A61B17/3207 , A61B17/00 , A61B90/00
摘要： A system for removal of blood or thrombus includes an aspiration catheter having an elongate shaft including an aspiration lumen having proximal end configured to couple to a vacuum source, and a distal end having an orifice, an elongate member configured for placement through the aspiration lumen and having a distal portion including a disruption element configured to disrupt thrombus within the aspiration lumen, and a monitoring device configured for removable connection in between the aspiration catheter and the vacuum source, and including a housing, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold.

19. 发明授权

US10603415B2 Aspiration monitoring system and method 有权
公开(公告)号：US10603415B2
公开(公告)日：2020-03-31
申请号：US15866414
申请日：2018-01-09
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61B17/22 , A61M1/00 , A61B17/00
摘要： In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.

20. 发明申请

US20180126049A1 ASPIRATION MONITORING SYSTEM AND METHOD 审中-公开
公开(公告)号：US20180126049A1
公开(公告)日：2018-05-10
申请号：US15866414
申请日：2018-01-09
申请人： INCUVATE, LLC
发明人： David M. Look , Bradley S. Culbert
IPC分类号： A61M1/00 , A61B17/22 , A61B17/00
CPC分类号： A61M1/0027 , A61B17/22 , A61B2017/00119 , A61B2017/00221 , A61B2217/005 , A61M1/0031 , A61M1/008 , A61M1/0086 , A61M2205/15 , A61M2205/18 , A61M2205/3327 , A61M2205/3331 , A61M2205/3355 , A61M2205/50 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.

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