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11. 发明授权

US5180666A Method and cell line for testing mutagenicity of a chemical 失效
标题翻译：用于测试化学品致突变性的方法和细胞系
公开(公告)号：US5180666A
公开(公告)日：1993-01-19
申请号：US721775
申请日：1991-06-27
申请人： J. Christopher States , Ronald N. Hines , Raymond F. Novak
发明人： J. Christopher States , Ronald N. Hines , Raymond F. Novak
IPC分类号： C12N5/22 , C12N9/02 , G01N33/50
CPC分类号： C12N9/0077 , G01N33/5017
摘要： A method of testing the mutagenicity of a chemical includes the steps of exposing test cells to the chemical in vitro, intracellularly metabolizing the chemical into a mutagenic or cytotoxic metabolite and then detecting gene/protein/cell damage in the test cells as an indication of the mutagenicity/cytotoxicity of the chemical.A cell line is provided for testing mutagenicity of the chemicals, the cell line consisting essentially of fibroblasts normally having no detectable cytochrome P450 mixed function oxidase enzyme activity. The fibroblasts are transformed with chimeric gene constructs containing cytochrome P450 coding sequences and have intracellular cytochrome P450 oxidative metaboli zing activity.
摘要翻译：测试化学品的致突变性的方法包括以下步骤：将测试细胞在体外暴露于化学物质，将细胞内代谢化学物质转化为诱变或细胞毒性代谢物，然后检测测试细胞中的基因/蛋白质/细胞损伤，作为化学品的致突变性/细胞毒性。提供了用于测试化学品致突变性的细胞系，细胞系基本上由通常不具有可检测的细胞色素P450混合功能氧化酶活性的成纤维细胞组成。用包含细胞色素P450编码序列的嵌合基因构建体转化成纤维细胞，并具有细胞内细胞色素P450氧化代谢活性。

12. 发明授权

US4320864A Muffler for fastener driving tool 失效
标题翻译：消声器用于紧固件驱动工具
公开(公告)号：US4320864A
公开(公告)日：1982-03-23
申请号：US152198
申请日：1980-05-22
申请人： Raymond F. Novak , Bernard W. Geist
发明人： Raymond F. Novak , Bernard W. Geist
IPC分类号： B25C1/04 , B25C9/00 , F01N1/10
CPC分类号： B25C1/047 , Y10S173/02
摘要： A tool for driving fasteners includes a housing defining a handle portion and a nose portion. A driver is reciprocally mounted within the housing as is an assembly for driving the driver through a fastener driving stroke. A muffler is mounted in the housing adjacent and in fluid communication with the nose portion. The muffler includes a chamber defined within the housing and a tubular muffler element mounted within the chamber. The tubular muffler element includes a plurality of holes therein and communicates with at least one exhaust port. A second muffler element is mounted within the chamber and encircles the tubular muffler element.
摘要翻译：用于驱动紧固件的工具包括限定手柄部分和鼻部部分的壳体。驾驶员可以相互安装在壳体内，如通过紧固件驱动行程驱动驾驶员的组件。消声器安装在壳体中，与鼻部相邻并且与鼻部流体连通。消声器包括限定在壳体内的腔室和安装在腔室内的管状消声器元件。管状消声器元件包括多个孔，并与至少一个排气口连通。第二消声器元件安装在腔室内并且环绕管状消音器元件。

13. 发明授权

US4319705A Fastener driving tool 失效
标题翻译：紧固件驱动工具
公开(公告)号：US4319705A
公开(公告)日：1982-03-16
申请号：US90009
申请日：1979-10-31
申请人： Bernard W. Geist , Raymond F. Novak
发明人： Bernard W. Geist , Raymond F. Novak
IPC分类号： B25C1/00 , B25C1/04
CPC分类号： B25C1/003 , B25C1/044 , B25C1/047 , Y10T29/4984
摘要： A tool for driving fasteners includes a casing defining a nose portion and a handle portion within which is a reservoir for pressurized fluid. A driver is mounted in the nose portion that is reciprocated by a piston attached thereto and an assembly for returning the piston to a static position after a driving stroke is also included. The return assembly includes a chamber in fluid communication through an inlet with pressurized air and with an outlet that is in communication with a location beneath the return piston. A diaphragm is mounted within the chamber and is biased by a shoe and spring into sealing engagement with the inlet and the outlet. Another metered inlet is also included in the chamber that is in fluid communication with the source of pressurized fluid and controls the sealing action of the diaphragm. The chamber for the return assembly is also in fluid communication with a second chamber within which is mounted a differential area piston. The piston includes a feed pawl for feeding fasteners to the driver from a magazine. The magazine is defined by two identical portions that are reversed upon assembly. Fasteners for the tool are fed from the magazine to the driver on a tape and each fastener is held by at least one tab. To prevent the fasteners from dislodging from the tape, the tool includes a shoe biased into engagement with the fastener and the tab.
摘要翻译：用于驱动紧固件的工具包括限定鼻部和手柄部分的壳体，在该部分内是用于加压流体的储存器。驱动器安装在通过附接到其上的活塞往复运动的鼻部中，并且还包括用于在驱动冲程之后将活塞返回到静止位置的组件。返回组件包括通过具有加压空气的入口流体连通的室和与回流活塞下方的位置连通的出口。隔膜安装在室内，并被鞋和弹簧偏压成与入口和出口密封接合。另外计量入口还包括在腔室中，其与加压流体源流体连通并且控制隔膜的密封作用。用于返回组件的腔室还与第二腔室流体连通，在其中安装有差动区域活塞。活塞包括用于从夹具将紧固件供给到驾驶员的进给爪。杂志由两个相同的部分限定，在组装时反向。用于工具的紧固件从盒子送到驱动器上，并且每个紧固件由至少一个接片保持。为了防止紧固件从带子上移开，工具包括一个与扣件和突片接合的鞋子。

14. 发明授权

US4304349A Fastener driving tool 失效
标题翻译：紧固件驱动工具
公开(公告)号：US4304349A
公开(公告)日：1981-12-08
申请号：US82916
申请日：1979-10-09
申请人： Raymond F. Novak , Chester A. Berry
发明人： Raymond F. Novak , Chester A. Berry
IPC分类号： B25C1/00 , B25C1/04 , B25C5/06 , B25C5/13 , B25C5/16
CPC分类号： B25C1/005 , B25C1/047
摘要： A fastener driving tool including a body having a handle and a head portion. A drive assembly includes a driver blade movable along a drive path defined by a nose assembly located below the head portion. A magazine assembly extends from the nose assembly and includes a frame member fixed relative to the tool body, a first track member slidably movable relative to the frame member and a second track member slidably movable relative to the first track member. The track members define a fastener slideway opened for loading of fasteners by movement of the second track member. The nose assembly includes a nose member mounted on the first track member, and movement of the first track member opens the feed path for removal of a jammed fastener. One track member is J-shaped for slidably supporting points of the fasteners and one side of the fastener shanks. The other track member slidably supports the opposite side of the fastener shanks.
摘要翻译：一种紧固件驱动工具，包括具有手柄和头部的本体。驱动组件包括可沿着位于头部下方的鼻部组件限定的驱动路径移动的驱动器刀片。弹匣组件从鼻部组件延伸并且包括相对于工具主体固定的框架构件，相对于框架构件可滑动地移动的第一轨道构件和相对于第一轨道构件可滑动地移动的第二轨道构件。轨道构件限定了通过第二轨道构件的移动来打开用于装载紧固件的紧固件滑道。鼻部组件包括安装在第一轨道构件上的鼻部构件，并且第一轨道构件的运动打开用于移除卡住的紧固件的进给路径。一个轨道构件是J形的，用于可滑动地支撑紧固件的点和紧固件柄的一侧。另一个轨道构件可滑动地支撑紧固件柄的相对侧。

15. 发明授权

US4005812A Electric fastener driving tool 失效
标题翻译：电动紧固件驱动工具
公开(公告)号：US4005812A
公开(公告)日：1977-02-01
申请号：US583847
申请日：1975-06-04
申请人： Richard H. Doyle , Salvatore L. Morabito , Andrew I. Yohana , Raymond F. Novak
发明人： Richard H. Doyle , Salvatore L. Morabito , Andrew I. Yohana , Raymond F. Novak
IPC分类号： B25C1/06 , B25C5/15
CPC分类号： B25C5/15 , B25C1/06
摘要： An electric fastener driving tool includes a body of clamshell construction formed of two, similar, molded plastic body parts. The body includes a head portion and a handle portion, and a magazine for supplying fasteners to be driven is supported by the base of the head portion and by the handle. Walls and projections integral with the body parts define a solenoid chamber within the head cavity and support a switch and circuit board within the handle. The body is held in assembled condition and the magazine is attached to the body by bolts of equal length. A solenoid with a central axial opening is mounted in the solenoid chamber. An armature formed of magnetic and nonmagnetic, electrically insulated segments is slidably mounted in the axial solenoid opening. A spring contacting an integral body wall and the insulating armature segment biases the armature in the return direction. A driver blade carried by the armature may be attached in electrically insulated fashion, and moves in a drive path into which fasteners are supplied from the magazine. A circuit including a switch controls energization of the solenoid, and a switch operating assembly provides for fail-safe operation and prevents unintentional multiple firing.
摘要翻译：电动紧固件驱动工具包括由两个类似的模制塑料体部分形成的蛤壳结构体。主体包括头部和把手部分，并且用于提供被驱动的紧固件的盒子由头部的基部和手柄支撑。与主体部分成一体的墙壁和突起在头腔内限定了一个电磁阀腔，并在手柄内支撑开关和电路板。主体被保持在组装状态，并且通过相等长度的螺栓将盒子附接到主体。具有中心轴向开口的螺线管安装在螺线管室中。由磁性和非磁性的电绝缘段形成的电枢可滑动地安装在轴向螺线管开口中。接触整体体壁的弹簧和绝缘电枢段沿着返回方向偏压衔铁。由电枢承载的驱动器刀片可以以电绝缘的方式附接，并且在从刀库供应紧固件的驱动路径中移动。包括开关的电路控制螺线管的通电，并且开关操作组件提供故障安全操作并且防止无意的多次点火。

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