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11. 发明申请

US20060247259A1 Nitrogen-containing aromatic derivatives 有权
公开(公告)号：US20060247259A1
公开(公告)日：2006-11-02
申请号：US11293785
申请日：2005-12-02
申请人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto
发明人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto
IPC分类号： A61K31/519 , A61K31/517 , A61K31/4745 , A61K31/4706 , C07D487/02 , C07D471/02
CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
摘要： Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.

12. 发明授权

US06486149B2 Composition comprising a crystallographically stable, amorphous cephalosporin and processes for the preparation thereof 有权
公开(公告)号：US06486149B2
公开(公告)日：2002-11-26
申请号：US09991694
申请日：2001-11-26
申请人： Masahiro Onodera , Masamichi Sukegawa , Kiyoshi Yasui , Tatsuo Watanabe , Toyomi Sato , Yasushi Murai , Katsuharu Iinuma
发明人： Masahiro Onodera , Masamichi Sukegawa , Kiyoshi Yasui , Tatsuo Watanabe , Toyomi Sato , Yasushi Murai , Katsuharu Iinuma
IPC分类号： A61K31545
CPC分类号： C07D501/00 , A61K9/146 , A61K31/545 , A61K31/546 , Y10S514/96
摘要： Processes are provided for the preparation of orally administrable, yellow and powdery compositions essentially consisting of particles composed of a homogeneous mixture of an amorphous Cefditoren pivoxil substance with a water soluble high-molecular additive. These compositions can be produced by dissolving crystalline Cefditoren pivoxil substance and the water-soluble high-molecular additive in an aqueous solution of an acid, then neutralizing the resultant solution, to co-precipitate the product, and drying the thus precipitated product, followed by recovering the product in the form of the above-mentioned particles.

13. 发明授权

US06342493B1 Crystallographically stable amorphous cephalosporin compositions and process for producing the same 有权
标题翻译：晶体学稳定的无定型头孢菌素组合物及其制备方法
公开(公告)号：US06342493B1
公开(公告)日：2002-01-29
申请号：US09582937
申请日：2000-07-07
申请人： Masahiro Onodera , Masamichi Sukegawa , Kiyoshi Yasui , Tatsuo Watanabe , Toyomi Sato , Yasushi Murai , Katsuharu Iinuma
发明人： Masahiro Onodera , Masamichi Sukegawa , Kiyoshi Yasui , Tatsuo Watanabe , Toyomi Sato , Yasushi Murai , Katsuharu Iinuma
IPC分类号： A61K31545
CPC分类号： C07D501/00 , A61K9/146 , A61K31/545 , A61K31/546 , Y10S514/96
摘要： Processes are provided for the preparation of orally administrable, yellow and powdery compositions essentially consisting of particles composed of a homogeneous mixture of an amorphous Cefditoren pivoxil substance with a water soluble high-molecular additive. These compositions can be produced by dissolving crystalline Cefditoren pivoxil substance and the water-soluble high-molecular additive in an aqueous solution of an acid, then neutralizing the resultant solution, to co-precipitate the product, and drying the thus precipitated product, followed by recovering the product in the form of the above-mentioned particles.
摘要翻译：提供了制备可口服的黄色和粉末状组合物的方法，其基本上由由无定形头孢托仑匹酯与水溶性高分子添加剂的均匀混合物组成的颗粒组成。这些组合物可以通过将结晶性匹戊头孢托仑物质和水溶性高分子添加剂溶解在酸的水溶液中，然后中和所得溶液，使产物共沉淀并干燥沉淀的产物，然后以上述颗粒的形式回收产物。

14. 发明授权

US4748622A Satellite communication system 失效
标题翻译：卫星通信系统
公开(公告)号：US4748622A
公开(公告)日：1988-05-31
申请号：US890235
申请日：1986-07-29
申请人： Takuro Muratani , Tatsuo Watanabe , Michihisa Ohkawa , Keiichiro Koga
发明人： Takuro Muratani , Tatsuo Watanabe , Michihisa Ohkawa , Keiichiro Koga
IPC分类号： H04B7/15 , H04B7/185 , H04J3/06
CPC分类号： H04B7/18578 , H04J3/0626
摘要： A satellite communication among a plurality of small earth stations (very small aperture terminal;VSAT) through a satellite is performed by using a relay earth station which has higher power than a small earth station. A signal goes from an originating small earth station to a destination small earth station, through a satellite, a relay earth station, and a satellite by using two hops propagation. Communication is carried out in digital form. The relay earth station regenerates digital signals from small earth stations. In the process of the regeneration of the digital signals, the error correction technique is applied to reduce the error rate, and a frequency compensation technique is also employed. Thus, a small simple earth station can provide high quality of communication with high C/N. A reference clock signal for operating a small earth station is derived from a reception signal from a satellite.
摘要翻译：通过使用具有比小地球站更高的功率的中继地球站，通过卫星进行多个小地球站（非常小的孔径终端; VSAT）之间的卫星通信。信号通过卫星，中继地球站和卫星通过使用两个跳传播从原始的小地球站到达目的地小地球站。沟通以数字形式进行。中继地球站从小地球站再生数字信号。在数字信号的再生过程中，采用纠错技术来降低误码率，并采用频率补偿技术。因此，一个小型简单的地球站可以提供高C / N的高质量通信。用于操作小型地球站的参考时钟信号是从卫星的接收信号导出的。

15. 发明授权

US4629996A Feed-forward microwave power amplifier with difference signal distortion cancellation circuit 失效
标题翻译：前馈微波功率放大器，具有差分信号失真消除电路
公开(公告)号：US4629996A
公开(公告)日：1986-12-16
申请号：US671849
申请日：1984-11-15
申请人： Tatsuo Watanabe , Kiyohiko Suzuki
发明人： Tatsuo Watanabe , Kiyohiko Suzuki
IPC分类号： H03F1/32 , H03F1/26
CPC分类号： H03F1/3229
摘要： A feed forward microwave power amplifier having a divider for dividing an input signal into two parts, a first main amplifier for amplifying one of the divided signals, means for providing a part of the output of the first amplifier as a signal S.sub.1, means for providing a signal S.sub.2 by another output of the divider, a subtractor for providing the difference between S.sub.2 and S.sub.1, a second amplifier having the same gain as that of the first amplifier for amplifying this difference, a 3 dB coupler for coupling an output S.sub.4 of the first amplifier and an output S.sub.4 e, where e is a constant, of the second amplifier to provide coupled power which is free from distortion, and adjusting means for adjusting the level of signals S.sub.1 and S.sub.2 so that S.sub.2 is higher than S.sub.1, and the value e is in the range between 0.2 and 0.5. The particular features of the present invention, compared with a prior feed forward amplifier, are the use of a 3 dB coupler, and the configuration of the second amplifier which accepts not only the distortion component but also some desired component of the output of the first amplifier.
摘要翻译：一种前馈微波功率放大器，具有用于将输入信号分成两部分的分频器，用于放大所分割信号中的一个的第一主放大器，用于将第一放大器的输出的一部分提供为信号S1的装置，通过分频器的另一输出的信号S2，用于提供S2和S1之间的差的减法器，具有与用于放大该差的第一放大器相同的增益的第二放大器，用于耦合第一放大器的输出S4的3dB耦合器第一放大器和第二放大器的e为常数的输出S4e，以提供没有失真的耦合功率，以及用于调整信号S1和S2的电平以使S2高于S1的调整装置，并且该值 e在0.2和0.5之间。与现有的前馈放大器相比，本发明的特征是使用3dB耦合器，并且第二放大器的配置不仅接受失真分量，而且还接受第一放大器的输出的一些期望分量放大器

16. 发明授权

US4580263A Signal quality monitoring device 失效
标题翻译：信号质量监控装置
公开(公告)号：US4580263A
公开(公告)日：1986-04-01
申请号：US544192
申请日：1983-10-21
申请人： Tatsuo Watanabe , Toshio Mizuno , Makoto Miyake , Tadashi Fujino
发明人： Tatsuo Watanabe , Toshio Mizuno , Makoto Miyake , Tadashi Fujino
IPC分类号： H04L1/00 , H04L1/24 , H04L25/02 , G06F11/00
CPC分类号： H04L1/241
摘要： The error rate of a signal is monitored by sampling an input signal with a first clock and also with second and third clocks phase delayed in equal but opposite directions with respect to the first clock, and then logically combining the first through third sampled outputs in order to obtain an error signal.
摘要翻译：通过用第一时钟采样输入信号以及相对于第一时钟以相等但相反的方向相位延迟的第二和第三时钟来监视信号的误码率，然后按顺序逻辑地组合第一至第三采样输出以获得错误信号。

17. 发明授权

US08629821B2 Display device with faster changing side image 失效
标题翻译：具有更快更换侧面图像的显示设备
公开(公告)号：US08629821B2
公开(公告)日：2014-01-14
申请号：US13229858
申请日：2011-09-12
申请人： Charlotte Wendy Michele Borgers , Benjamin John Broughton , Kenji Maeda , Tatsuo Watanabe
发明人： Charlotte Wendy Michele Borgers , Benjamin John Broughton , Kenji Maeda , Tatsuo Watanabe
IPC分类号： G09G3/00 , G09G5/00 , G06F3/038
CPC分类号： G09G3/3648 , G09G2320/0242 , G09G2320/028
摘要： A display device is provided which includes a liquid crystal display panel including a plurality of pixels each having one or more sub-pixels; and control electronics configured to provide, in response to image data, signal voltages to the pixels in a first mode whereby an on-axis viewer and an off-axis viewer perceive substantially a same main image, and signal voltages to the pixels in a second mode whereby the on-axis viewer perceives the main image and the off-axis viewer perceives a side image different from the main image.
摘要翻译：提供了一种显示装置，其包括：液晶显示面板，包括具有一个或多个子像素的多个像素; 以及控制电子设备，被配置为响应于图像数据向第一模式中的像素提供信号电压，由此轴上观看者和离轴观看者感知到基本相同的主图像，并且在第二模式中向像素提供信号电压模式，其中在轴观看者感知主图像，而离轴观看者感知到与主图像不同的侧面图像。

18. 发明授权

US07612092B2 Nitrogen-containing aromatic derivatives 有权
标题翻译：含氮芳香族衍生物
公开(公告)号：US07612092B2
公开(公告)日：2009-11-03
申请号：US11293785
申请日：2005-12-02
申请人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui
发明人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui
IPC分类号： A61K31/47
CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
摘要： Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.
摘要翻译：由以下通式表示的化合物：其中Ag是任选取代的5至14元杂环基等; Xg为-O-，-S-等; Yg是任选取代的C 6-14芳基，任选取代的5至14元杂环基等; Tg1为下列通式表示的基团：（其中Eg为单键或-N（Rg2） - ，Rg1和Rg2各自独立地表示氢原子，可以具有取代基的C1-6烷基等，Zg 表示C 1-8烷基，C 3-8脂环族烃基，C 6-14芳基等）]，其盐或前述的水合物。

19. 发明授权

US07414075B2 Composition for lowering internal lipid content 有权
标题翻译：用于降低内部脂质含量的组合物
公开(公告)号：US07414075B2
公开(公告)日：2008-08-19
申请号：US11107745
申请日：2005-04-18
申请人： Yumiko Tani , Tatsuo Watanabe , Masanori Kamei , Masatoshi Kato , Koji Yanae
发明人： Yumiko Tani , Tatsuo Watanabe , Masanori Kamei , Masatoshi Kato , Koji Yanae
IPC分类号： A61K31/22 , A61K31/23
CPC分类号： A61K31/222 , A23L33/105
摘要： A composition for lowering internal lipid in a subject which contains a capsinoid substance represented by the following formula wherein n is an integer from 0 to 10. Methods of using the compositions are disclosed and include administering to a subject in need of such treatment.
摘要翻译：用于降低受试者内部脂质的组合物，其含有由下式表示的类毒素物质，其中n为0至10的整数。使用所述组合物的方法包括给予需要这种治疗的受试者。

20. 发明授权

US06649367B2 Human cancer cell line malignantly altered by expression of angiogenic factor 失效
标题翻译：人类癌细胞系通过血管生成因子的表达恶性改变
公开(公告)号：US06649367B2
公开(公告)日：2003-11-18
申请号：US10084686
申请日：2002-02-26
申请人： Yuji Yamamoto , Yasuhiro Funahashi , Kenichi Nomoto , Tatsuo Watanabe
发明人： Yuji Yamamoto , Yasuhiro Funahashi , Kenichi Nomoto , Tatsuo Watanabe
IPC分类号： C12Q102
CPC分类号： G01N33/5011 , G01N2500/20
摘要： A method for producing a cell to which angiogenesis-inducing ability has been imparted, comprising the steps of introducing a gene of an angiogenic factor into a human or animal cell having low angiogenesis-inducing ability, and selecting a cell that overexpresses the angiogenic factor; and a method for screening for an angiogenesis inhibitor or a substance having anticancer activity by using the produced cell.
摘要翻译：一种生产具有血管发生诱导能力的细胞的方法，包括以下步骤：将血管生成因子的基因导入具有低血管发生诱导能力的人或动物细胞中，并选择过表达血管生成因子的细胞; 以及通过使用所制造的细胞筛选血管生成抑制剂或具有抗癌活性的物质的方法。

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