专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08343350B2 Membrane, device and method for removing proteases from liquids 有权
标题翻译：从液体中去除蛋白酶的膜，装置和方法
公开(公告)号：US08343350B2
公开(公告)日：2013-01-01
申请号：US10516405
申请日：2003-06-17
申请人： Wolfgang Demmer , Dietmar Nussbaumer , Hans-Heinrich Hörl
发明人： Wolfgang Demmer , Dietmar Nussbaumer , Hans-Heinrich Hörl
IPC分类号： B01D15/00
CPC分类号： C07K14/81 , B01D15/00 , B01D15/3814 , B01D61/00 , B01D67/0093 , B01D69/14 , B01J20/28033 , B01J20/2808 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/3274 , C07K14/8107
摘要： The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
摘要翻译：本发明包括用于从流体，特别是从生物流体和药物溶液中去除蛋白酶的膜和装置和方法，其使用微孔膜体，由此通过化学活化的基团将选择性结合蛋白酶的抑制剂偶联到膜体上。

12. 发明授权

US06911148B1 Adsorptive membrane device for treating particle-laden liquid feeds 失效
标题翻译：用于处理含有颗粒的液体进料的吸附膜装置
公开(公告)号：US06911148B1
公开(公告)日：2005-06-28
申请号：US09936065
申请日：2000-09-06
申请人： Wolfgang Demmer , Dietmar Nussbaumer
发明人： Wolfgang Demmer , Dietmar Nussbaumer
IPC分类号： B01D63/08 , B01D15/08 , B01D61/00 , B01D61/18 , B01J20/28 , C07K1/16 , B01D63/00
CPC分类号： B01J20/28033 , B01D61/00 , B01D61/18 , B01J20/28052 , B01J20/28085
摘要： There is disclosed a device for the simultaneous separation of particles and target substances from liquid feeds by adsorption membranes having particle-passing apertures therein.
摘要翻译：公开了一种用于通过其中具有颗粒通过孔的吸附膜从液体进料同时分离颗粒和目标物质的装置。

13. 发明授权

US06491869B1 Method for preparing assay supports having an ordered set of reaction zones 失效
标题翻译：用于制备具有有序的反应区组的测定载体的方法
公开(公告)号：US06491869B1
公开(公告)日：2002-12-10
申请号：US09214244
申请日：1999-05-10
申请人： Wolfgang Demmer , Dietmar Nussbaumer , Khuong To Vinh , Thang Thuong Nguyen , Edwige Bonfils , Daniel Dupret
发明人： Wolfgang Demmer , Dietmar Nussbaumer , Khuong To Vinh , Thang Thuong Nguyen , Edwige Bonfils , Daniel Dupret
IPC分类号： G01N3348
CPC分类号： G01N33/543
摘要： The abstract discloses a method for preparing supports for the assay of chemical or biological substances, consisting in preparing N different supports, each being homogeneous for a type of reaction, then in mutually combining, according to a predetermined arrangement, all or part of the said homogenous N supports to constitute assay supports having each an ordered set of reaction zones of N different types or less. The invention also concerns the assay supports prepared by this method and their use in processes of immunological hybridisation assays.
摘要翻译：该摘要公开了一种制备用于化学或生物物质测定的载体的方法，其包括制备N种不同的载体，每种载体对于一种反应是均匀的，然后根据预定的布置相互组合，全部或部分所述均质N载体构成测定载体，其具有N个不同类型或更少种类的有序反应区组。本发明还涉及通过该方法制备的测定载体及其在免疫杂交测定方法中的应用。

14. 发明授权

US06294090B1 Adsorptive substance separation device 有权
标题翻译：吸附物分离装置
公开(公告)号：US06294090B1
公开(公告)日：2001-09-25
申请号：US09397456
申请日：1999-09-16
申请人： Dietmar Nussbaumer , Khoung To Vinh , Abdul Weiss , Wolfgang Demmer , Hans-Heinrich Hörl , Andreas Graus , Günter Pradel
发明人： Dietmar Nussbaumer , Khoung To Vinh , Abdul Weiss , Wolfgang Demmer , Hans-Heinrich Hörl , Andreas Graus , Günter Pradel
IPC分类号： B01D6310
CPC分类号： C07K14/805 , B01D61/00 , G01N30/60
摘要： An adsorptive separation device is disclosed having at least one spiral wound adsorption membrane situated around the periphery of a core mandrel wherein the flow is radial from a feed plenum situated between the core mandrel and the membrane, through the membrane to a permeate plenum located between the membrane and a housing for both the core mandrel and the spiral wound membrane. An array of such separation devices is also disclosed showing connections in parallel, in series, in both parallel and in series and in tandem.
摘要翻译：公开了一种吸附分离装置，其具有位于芯心周边周围的至少一个螺旋缠绕的吸附膜，其中流动是从位于芯心轴和膜之间的进料气室径向通过膜到位于膜和用于芯心轴和螺旋缠绕膜的壳体。还公开了这样的分离装置的阵列，它们并联地串联并联并串联并串联连接。

15. 发明授权

US06287461B1 Tandem system for adsorptive separation 有权
标题翻译：用于吸附分离的串联系统
公开(公告)号：US06287461B1
公开(公告)日：2001-09-11
申请号：US09397457
申请日：1999-09-16
申请人： Wolfgang Demmer , Dietmar Nussbaumer , Abdul Weiss
发明人： Wolfgang Demmer , Dietmar Nussbaumer , Abdul Weiss
IPC分类号： B01D1500
CPC分类号： B01D61/00
摘要： Adsorptive separation is performed on liquid media by directing the media containing a target substance through an adsorber stage A whereby the target substance is adsorbed; in the last phase of loading stage A and prior to breakthrough of the target substance in the stage A permeate, the stage A permeate is directed to a second adsorber stage B. Upon completion of the stage A loading, the target substance from stage A is eluted with buffer solution, which buffer solution is introduced to stage B, and liquid medium is directed to the preloaded stage A, while stage A is eluted so as both recover the target substance and regenerate the adsorptive capacity of stage A.
摘要翻译：通过将含有目标物质的介质引导通过吸附器阶段A来吸附目标物质，对液体介质进行吸附分离; 在装载阶段A的最后阶段和在阶段A渗透物中的目标物质的穿透之前，阶段A渗透物被引导到第二吸附阶段B.在阶段A装载完成后，来自阶段A的目标物质为用缓冲溶液洗脱，将该缓冲溶液引入阶段B，将液体培养基导入预加载阶段A，同时洗脱阶段A，同时回收目标物质并再生阶段A的吸附能力。

16. 发明授权

US6001974A Method of separating albumin from serum by ion-exchange chromatography with membrane adsorbers 失效
标题翻译：通过离子交换色谱法用膜吸附器从血清中分离白蛋白的方法
公开(公告)号：US6001974A
公开(公告)日：1999-12-14
申请号：US41082
申请日：1998-03-10
申请人： Wolfgang Demmer , Heinrich Klaus Gebauer , Maria-Regina Kula , Dietmar Nussbaumer , Jorg Thoemmes
发明人： Wolfgang Demmer , Heinrich Klaus Gebauer , Maria-Regina Kula , Dietmar Nussbaumer , Jorg Thoemmes
IPC分类号： C07K1/18 , C07K14/765
CPC分类号： C07K14/765
摘要： A method of separating albumin from serum by ion exchange chromatography with membrane adsorbers characterized by high productivity and yields of high purity albumin. The separation of the albumin is carried out on highly basic anion exchange membranes and on highly acidic cation exchange membranes. The albumin fraction can be eluted from the anion exchange membrane such that it can be fed directly to the cation exchange membrane without any special conditioning and the albumin can be extracted therefrom as an end product.
摘要翻译：通过离子交换色谱法分离白蛋白的方法，其中膜吸附剂的特征在于高生产率和高纯度白蛋白的产率。白蛋白的分离是在高度碱性的阴离子交换膜和高度酸性的阳离子交换膜上进行的。白蛋白部分可以从阴离子交换膜中洗脱出来，使得其可以直接进料至阳离子交换膜而无需任何特殊的调理，并且可以从其中提取白蛋白作为终产物。

17. 发明授权

US08343351B2 Membrane for removing proteases from liquids 有权
标题翻译：从液体中除去蛋白酶的膜
公开(公告)号：US08343351B2
公开(公告)日：2013-01-01
申请号：US11436861
申请日：2006-05-17
申请人： Wolfgang Demmer , Dietmar Nussbaumer , Hans-Heinrich Hörl
发明人： Wolfgang Demmer , Dietmar Nussbaumer , Hans-Heinrich Hörl
IPC分类号： B01D15/00
CPC分类号： C07K14/81 , B01D15/00 , B01D15/3814 , B01D61/00 , B01D67/0093 , B01D69/14 , B01J20/28033 , B01J20/2808 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/3274 , C07K14/8107
摘要： The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
摘要翻译：本发明包括用于从流体，特别是从生物流体和药物溶液中去除蛋白酶的膜和装置和方法，其使用微孔膜体，由此通过化学活化的基团将选择性结合蛋白酶的抑制剂偶联到膜体上。

18. 发明授权

US06235892B1 Process for the purification of nucleic acids 有权
标题翻译：核酸纯化方法
公开(公告)号：US06235892B1
公开(公告)日：2001-05-22
申请号：US09468706
申请日：1999-12-21
申请人： Wolfgang Demmer , Dietmar Nussbaumer
发明人： Wolfgang Demmer , Dietmar Nussbaumer
IPC分类号： C07H2100
CPC分类号： C12N15/1017
摘要： There is disclosed a membrane process for the purification of nucleic acids in aqueous solutions whereby a lasting reduction of endotoxin content is achieved. The process is suitable for small or large volumes and can be carried out quickly and with simple apparatus.
摘要翻译：公开了一种用于在水溶液中纯化核酸的膜方法，由此实现了内毒素含量的持续降低。该方法适用于小型或大容量，可以快速，简单的装置进行。

19. 发明申请

US20070006734A1 Membrane holder for membrane adsorber chromotography 有权
标题翻译：薄膜吸附器色谱膜支架
公开(公告)号：US20070006734A1
公开(公告)日：2007-01-11
申请号：US11454047
申请日：2006-06-15
申请人： Wolfgang Demmer , Rene Faber
发明人： Wolfgang Demmer , Rene Faber
IPC分类号： B01D53/02
CPC分类号： B01D15/22 , B01J20/28033
摘要： Membrane holder for membrane adsorber chromatography comprising a housing body (12) with a reception space for at least one layer of adsorber membranes (22) and at least one first housing cap (34) for closing a first reception space opening, which can be fixed to the housing body (12), a liquid stream being introducible via first liquid guide means (36) through the first housing cap (34) and the first reception opening into the reception opening, so that it passes through the adsorber membranes (22) and flows away through a second reception space opening. The first housing cap (34) can be screwed as a first union nut onto the housing body (12) and a first brace element (24), which can be clamped between the first cap (34) and the housing body (12) via a flange (32) extending beyond the first reception space opening, can be fixed leaktightly in a basket-like insert (14) with a liquid-tight wall and a perforated bottom (18), which is used to receive the adsorber membranes (22). The outer contour of the basket-like insert (14) being fitted in a leaktight fashion onto an inner contour of the reception space.
摘要翻译：用于膜吸附器色谱的膜支架包括具有用于至少一层吸附膜（22）的接收空间的壳体（12）和用于封闭第一接收空间开口的至少一个第一壳体盖（34），该第一容纳帽可固定通过第一液体引导装置（36）可以通过第一壳体盖（34）和第一接收孔引入到容纳体（12）中的液体流，使其通过吸附膜（22），并通过第二接收空间开口流出。第一壳体盖（34）可以作为第一联接螺母旋拧到壳体（12）上，第一支撑元件（24）可以通过第一支承元件（24）夹紧在第一盖（34）和壳体（12）之间延伸超过第一接收空间开口的凸缘（32）可以用液体密封壁和穿孔底部（18）密封地固定在篮状插入件（14）中，用于接收吸附膜（22））。篮状插入件（14）的外轮廓以密封方式装配到接收空间的内轮廓上。

20. 发明授权

US08969094B2 Method for qualifying a non-particulate ion-exchanger adsorber 有权
标题翻译：非微粒离子交换吸附剂的鉴定方法
公开(公告)号：US08969094B2
公开(公告)日：2015-03-03
申请号：US13517153
申请日：2010-11-10
申请人： Wolfgang Demmer , Rene Faber , Hans-Heinrich Hoerl , Axel Thiefes
发明人： Wolfgang Demmer , Rene Faber , Hans-Heinrich Hoerl , Axel Thiefes
IPC分类号： G01N31/16 , G01N30/88 , G01N30/96
CPC分类号： G01N30/88 , G01N30/96 , G01N2030/889
摘要： The present invention relates to a method for the validation of a non-particulate ion exchange adsorber and a kit for the validation of a non-particulate ion exchange adsorber.
摘要翻译：本发明涉及非微粒离子交换吸附剂的验证方法和非微粒离子交换吸附剂验证试剂盒。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式