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11. 发明申请

US20080057265A1 Electromagnetic Interference Shielding Structure Including Carbon Nanotubes and Nanofibers 审中-公开
标题翻译：包括碳纳米管和纳米纤维的电磁干扰屏蔽结构
公开(公告)号：US20080057265A1
公开(公告)日：2008-03-06
申请号：US11751655
申请日：2007-05-22
申请人： Zhiyong Liang , Ben Wang , Chun Zhang
发明人： Zhiyong Liang , Ben Wang , Chun Zhang
IPC分类号： B05D5/12 , B29C65/00 , B29C65/02 , B29C65/48 , B32B33/00 , B32B5/12
CPC分类号： B32B5/02 , B32B33/00 , H05K9/009 , Y10T156/10 , Y10T428/24132 , Y10T428/249953 , Y10T428/265 , Y10T428/31504 , Y10T428/8305
摘要： Electromagnetic interference (EMI) shielding structure and methods of making such structures are provided. In one case, a method is provided for making a lightweight composite structure for electromagnetic interference shielding, including the steps of providing a nanoscale fiber film which comprises a plurality of nanoscale fibers; and combining the nanoscale fiber film with one or more structural materials to form a composite material which is effective as an electromagnetic interference shielding structure. In another case, a method is provided for shielding a device which includes an electrical circuit from electromagnetic interference comprising the steps of providing a nanoscale fiber film which comprises a plurality of nanoscale fibers; and incorporating the nanoscale fiber film into an exterior portion of the device to shield an interior portion of the device from electromagnetic interference.
摘要翻译：提供电磁干扰（EMI）屏蔽结构和制造这种结构的方法。在一种情况下，提供了一种用于制造用于电磁干扰屏蔽的轻质复合结构的方法，包括提供包括多个纳米级纤维的纳米级纤维膜的步骤; 并且将纳米级纤维膜与一种或多种结构材料结合以形成作为电磁干扰屏蔽结构有效的复合材料。在另一种情况下，提供了一种用于屏蔽包括电磁干扰电路的设备的方法，包括以下步骤：提供包括多个纳米级纤维的纳米级纤维膜; 并将纳米尺度纤维膜并入设备的外部部分以屏蔽设备的内部免受电磁干扰。

12. 发明申请

US20070012856A1 Auto-eject foot stand assembly with multi-viewing angles 失效
标题翻译：具有多视角自动排出脚架组件
公开(公告)号：US20070012856A1
公开(公告)日：2007-01-18
申请号：US11455443
申请日：2006-06-19
申请人： Kwai Nam Chan , Chun Zhang , Sin Cheah
发明人： Kwai Nam Chan , Chun Zhang , Sin Cheah
IPC分类号： F16M7/00
CPC分类号： F16M11/10 , F16M13/005 , F16M2200/041 , G06F1/1626 , G06F1/166
摘要： An auto-eject foot stand assembly with multi-viewing angles for a visual device includes a foot having an axle perpendicular to the foot. The axle rotatably extends in a bracket. A gear is securely provided outside the axle and between the bracket and the foot. A spring is provided between the gear and the bracket. An elasticity plate is engaged with the gear. A locker is pivotally mounted on the bracket and operated by a metal spring plate to lock the gear. When the metal spring plate is pressed, the gear is released from the locker and the foot can be ejected under the elastic force of the spring. By the engagement between the gear and elasticity plate, the foot can be rotated and positioned at various desired viewing angels.
摘要翻译：具有用于视觉装置的多视角的自动弹出脚架组件包括具有垂直于脚的轴的脚。轴可旋转地延伸在支架中。齿轮牢固地设置在车轴的外侧，并且在支架和脚之间。在齿轮和支架之间设有弹簧。弹性板与齿轮啮合。储物柜枢转地安装在支架上并由金属弹簧板操作以锁定齿轮。当金属弹簧板被按压时，齿轮从储物柜释放，并且脚可以在弹簧的弹力下弹出。通过齿轮和弹性板之间的接合，脚可以旋转并定位在各种所需的观看天使。

13. 发明申请

US20060207931A1 Method for continuous fabrication of carbon nanotube networks or membrane materials 有权
标题翻译：连续制造碳纳米管网络或膜材料的方法
公开(公告)号：US20060207931A1
公开(公告)日：2006-09-21
申请号：US11185513
申请日：2005-07-20
申请人： Zhiyong Liang , Ben Wang , Chun Zhang , Jonnattan Ugarte , Chih-Yen Lin , James Thagard
发明人： Zhiyong Liang , Ben Wang , Chun Zhang , Jonnattan Ugarte , Chih-Yen Lin , James Thagard
IPC分类号： B01D71/00
CPC分类号： B01D69/10 , B01D67/0046 , B01D71/021 , B01D2323/22 , B01D2323/35 , B01D2323/46 , B82Y30/00 , Y10S264/902 , Y10S977/742 , Y10S977/755
摘要： Methods and devices are provided for the continuous production of a network of nanotubes or other nanoscale fibers. The method includes making a suspension of nanoscale fibers dispersed in a liquid medium, optionally with surfactant and/or sonication, and filtering the suspension by moving a filter membrane through the suspension, such that the nanoscale fibers are deposited directly on the filter membrane as the fluid medium flows through the filter membrane, thereby forming a continuous membrane of the nanoscale fibers. The deposition of the nanoscale fibers can occur when and where the filter membrane moves into contact with a static, porous filter element or a dynamic, porous filter element. The filtering can be conducted within a magnetic field effective to align the nanoscale fibers, and/or with the aid of vacuum to pull water through the filter membrane, applied pressure to press water though the filter membrane, or a combination thereof.
摘要翻译：提供了用于连续生产纳米管或其他纳米级纤维网络的方法和装置。该方法包括制备分散在液体介质中的纳米尺度纤维的悬浮液，任选地用表面活性剂和/或超声处理，并且通过移动过滤膜通过悬浮液来过滤悬浮液，使得纳米级纤维直接沉积在过滤膜上作为流体介质流过过滤膜，从而形成纳米级纤维的连续膜。纳米尺度纤维的沉积可以在滤膜与静止的多孔过滤元件或动态多孔过滤元件接触时发生。过滤可以在有效地对准纳米尺度纤维的磁场中和/或借助于真空来进行，以将水通过过滤膜，施加压力以通过过滤膜压制水或其组合。

14. 发明授权

US09475806B2 Complement factor B inhibitors and uses there of 有权
标题翻译：补体因子B抑制剂及其用途
公开(公告)号：US09475806B2
公开(公告)日：2016-10-25
申请号：US14774430
申请日：2014-03-13
申请人： Christopher Michael Adams , Charles Babu , Michael Paul Capparelli , Jian Ding , Takeru Ehara , Keith Jendza , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Liang Xue , Nello Mainolfi , James J. Powers , Michael H. Serrano-Wu , Chun Zhang
发明人： Christopher Michael Adams , Charles Babu , Michael Paul Capparelli , Jian Ding , Takeru Ehara , Keith Jendza , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Liang Xue , Nello Mainolfi , James J. Powers , Michael H. Serrano-Wu , Chun Zhang
IPC分类号： C07D401/14 , A61K31/4353 , A61K31/437 , C07D471/04
CPC分类号： C07D471/04
摘要： The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents.

15. 发明授权

US09193967B2 Pegylated analogue protein or canine urate oxidase, preparation method and use thereof 有权
标题翻译：聚乙二醇化类似蛋白或犬尿酸氧化酶，其制备方法和用途
公开(公告)号：US09193967B2
公开(公告)日：2015-11-24
申请号：US13985273
申请日：2012-02-14
申请人： Chun Zhang , Kai Fan , Xuefeng Ma , Li Yang , Chunlan Hu , Hua Luo , Xiang Mei
发明人： Chun Zhang , Kai Fan , Xuefeng Ma , Li Yang , Chunlan Hu , Hua Luo , Xiang Mei
IPC分类号： A61K48/00 , C12N9/96 , A61K47/48 , C12N9/06 , A61K38/00
CPC分类号： C12N9/96 , A61K38/00 , A61K47/60 , C12N9/0048 , C12Y107/03003
摘要： Provided are a PEGylated analogue protein of canine urate oxidase, preparation method and use thereof. The analogue protein of canine urate oxidase is a canine urate oxidase, or a chimeric protein comprising part of the amino acid sequence of a canine urate oxidase and part of the amino acid sequence of a human urate oxidase, or a mutant protein thereof. The PEGylated analogue protein of canine urate oxidase and pharmaceutical compositions thereof according to the present invention can be used for the prevention and/or treatment of hyperuricemia and chronic gout.
摘要翻译：提供犬尿酸氧化酶的聚乙二醇化类似蛋白，其制备方法和用途。犬尿酸氧化酶的类似蛋白是犬尿酸氧化酶，或包含犬尿酸氧化酶的部分氨基酸序列和人尿酸氧化酶的部分氨基酸序列的嵌合蛋白或其突变蛋白。犬尿酸氧化酶的聚乙二醇化类似物蛋白及其药物组合物可用于预防和/或治疗高尿酸血症和慢性痛风。

16. 发明授权

US08784603B2 Actuator device including nanoscale fiber films 有权
标题翻译：执行机构包括纳米纤维膜
公开(公告)号：US08784603B2
公开(公告)日：2014-07-22
申请号：US12430455
申请日：2009-04-27
申请人： Zhiyong Liang , Ben Wang , Chun Zhang , Szu-Yuan Tsai , Leslie Kramer
发明人： Zhiyong Liang , Ben Wang , Chun Zhang , Szu-Yuan Tsai , Leslie Kramer
IPC分类号： B32B37/00 , B82Y15/00 , H01L41/45
CPC分类号： B82Y15/00 , H01L41/45 , Y10T156/1092 , Y10T428/249924
摘要： A method for making an actuator capable of dry actuation is provided. The method includes providing a first nanoscale fiber film, providing a second nanoscale fiber film, positioning a solid polymer electrolyte at least partially between and adjacent to the first nanoscale fiber film and the second nanoscale fiber film, and then affixing the solid polymer electrolyte to the first nanoscale fiber film and the second nanoscale fiber film. The nanoscale fiber films may be buckypapers, made of carbon nanotubes. The actuator is capable of dry actuation.
摘要翻译：提供了一种用于制造能够进行干式致动的致动器的方法。该方法包括提供第一纳米尺度纤维膜，提供第二纳米级纤维膜，将固体聚合物电解质至少部分地定位在第一纳米尺度纤维膜和第二纳米尺度纤维膜之间和之后，然后将固体聚合物电解质固定在第一纳米级纤维膜和第二纳米纤维膜。纳米尺度的纤维膜可以是由碳纳米管制成的压缩纸。执行器能够干式启动。

17. 发明授权

US08703355B2 Catalytic electrode with gradient porosity and catalyst density for fuel cells 有权
标题翻译：催化电极具有梯度孔隙率和燃料电池的催化剂密度
公开(公告)号：US08703355B2
公开(公告)日：2014-04-22
申请号：US12839124
申请日：2010-07-19
申请人： Chun Zhang , Wei Zhu , Jian-ping Zheng , Zhiyong Liang , Ben Wang
发明人： Chun Zhang , Wei Zhu , Jian-ping Zheng , Zhiyong Liang , Ben Wang
IPC分类号： H01M8/10 , H01M4/88
CPC分类号： H01M4/8642 , B82Y30/00 , C04B2235/5288 , H01M4/8657 , H01M4/8807 , H01M4/8892 , H01M4/92 , H01M4/926 , H01M8/0234 , H01M8/0245 , H01M8/1004 , Y02P70/56
摘要： A membrane electrode assembly (MEA) for a fuel cell comprising a gradient catalyst structure and a method of making the same. The gradient catalyst structure can include a plurality of catalyst nanoparticles, e.g., platinum, disposed on layered buckypaper. The layered buckypaper can include at least a first layer and a second layer and the first layer can have a lower porosity compared to the second layer. The gradient catalyst structure can include single-wall nanotubes, carbon nanofibers, or both in the first layer of the layered buckypaper and can include carbon nanofibers in the second layer of the layered buckypaper. The MEA can have a catalyst utilization efficiency of at least 0.35 gcat/kW or less.
摘要翻译：一种用于燃料电池的膜电极组件（MEA），其包括梯度催化剂结构及其制备方法。梯度催化剂结构可以包括设置在分层压滤纸上的多个催化剂纳米颗粒，例如铂。所述分层消音器可以包括至少第一层和第二层，并且与第二层相比，第一层可以具有较低的孔隙率。梯度催化剂结构可以包括单层纳米管，碳纳米纤维或层状降压纸的第一层中的两者，并且可以在层叠的消泡剂的第二层中包括碳纳米纤维。 MEA的催化剂利用效率至少为0.35gcat / kW以下。

18. 发明授权

US08586535B2 Humanized recombinant uricase and mutants thereof 有权
标题翻译：人源化重组尿酶及其突变体
公开(公告)号：US08586535B2
公开(公告)日：2013-11-19
申请号：US13504065
申请日：2010-03-12
申请人： Kai Fan , Chun Zhang , Xuefeng Ma , Xiang Mei , Chunlan Hu
发明人： Kai Fan , Chun Zhang , Xuefeng Ma , Xiang Mei , Chunlan Hu
IPC分类号： A61K38/00 , C07K1/00 , C12N9/06
CPC分类号： C12Y107/03003 , A61K38/00 , C12N9/0012 , C12N9/0048
摘要： The present invention provides a humanized recombinant uricase and mutants thereof, wherein the humanized recombinant uricase is a chimeric protein which comprises amino acids of non-human mammal uricase and amino acids of human uricase. The humanized recombinant unease and mutants thereof have reduced immunogenicity in human, and can be used for the treatment of hyperuricemia and gout.
摘要翻译：本发明提供人源化重组尿酸酶及其突变体，其中人源化重组尿酶是包含非人哺乳动物尿酸酶氨基酸和人尿酸酶氨基酸的嵌合蛋白。人源化重组不安及其突变体在人体中具有降低的免疫原性，可用于治疗高尿酸血症和痛风。

19. 发明授权

US08557771B2 Homodimer of insulinotropic peptide analogues and method for preparation thereof and use thereof 有权
标题翻译：促胰岛素肽类似物的同型二聚体及其制备方法及其用途
公开(公告)号：US08557771B2
公开(公告)日：2013-10-15
申请号：US13391097
申请日：2010-03-15
申请人： Kai Fan , Zhiquan Zhao , Yong Chen , Chun Zhang , Lin Wang
发明人： Kai Fan , Zhiquan Zhao , Yong Chen , Chun Zhang , Lin Wang
IPC分类号： C07K19/00 , A61P3/00 , A61K38/26 , C07K14/43
CPC分类号： C07K14/43 , A61K38/00 , C07K14/50 , C07K14/605 , C07K2319/00
摘要： Provided is a homodimer of insulinotropic peptide analogues and method for preparation thereof and use thereof, wherein the insulinotropic peptide analogue comprises GLP-1 and Exendin-4. The homodimer of insulinotropic peptide analogues of the invention is made by conjugating two identical insulinotropic peptide analogue molecules at the C-terminal Cys residues via disulfide bond or PEG molecule. The homodimer of insulinotropic peptide analogues of the invention has superior stability and biological activity in vivo, and prolonged half-life in the circulation, and can be used for the preparation of hypoglycemic drugs.
摘要翻译：提供促胰岛素肽类似物的同型二聚体及其制备方法及其应用，其中促胰岛素肽类似物包含GLP-1和毒蜥外泌肽-4。本发明的促胰岛素肽类似物的同型二聚体通过在C末端Cys残基上通过二硫键或PEG分子缀合两个相同的促胰岛素肽类似物分子来制备。本发明的促胰岛素肽类似物的同型二聚体在体内具有优异的稳定性和生物活性，并且循环中的半衰期延长，并且可用于制备降血糖药物。

20. 发明授权

US08351220B2 Electromagnetic interference shielding structure including carbon nanotube or nanofiber films and methods 有权
标题翻译：包括碳纳米管或纳米纤维膜的电磁干扰屏蔽结构及方法
公开(公告)号：US08351220B2
公开(公告)日：2013-01-08
申请号：US12695850
申请日：2010-01-28
申请人： Zhiyong Liang , Ben Wang , Chun Zhang , Jin Gyu Park
发明人： Zhiyong Liang , Ben Wang , Chun Zhang , Jin Gyu Park
IPC分类号： H05K9/00
CPC分类号： H05K9/0088 , B82Y30/00 , H01B1/04 , H05K9/009 , Y10S977/832
摘要： A composite material for electromagnetic interference shielding is provided. The composite material comprises a stack including at least two electrically conductive nanoscale fiber films, which are spaced apart from one another by at least one insulating gap positioned between the at least two nanoscale fiber films. The stack is effective to provide a substantial multiple internal reflection effect. An electromagnetic interference shielded apparatus and a method for shielding an electrical circuit from electromagnetic interference is provided.
摘要翻译：提供了一种用于电磁干扰屏蔽的复合材料。所述复合材料包括包括至少两个导电纳米级纤维膜的叠层，它们通过位于所述至少两个纳米级纤维膜之间的至少一个绝缘间隙彼此间隔开。该堆叠对于提供实质的多重内部反射效果是有效的。提供一种电磁干扰屏蔽装置和一种屏蔽电路免受电磁干扰的方法。

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