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    • 17. 发明授权
    • Automatic adjustment of detection rate threshold in an implantable
antitachycardia therapy device
    • 在植入式抗心律失常治疗装置中自动调整检测率阈值
    • US5882352A
    • 1999-03-16
    • US449970
    • 1995-05-25
    • James L. DuncanBruce WilkoffJames D. Causey, III
    • James L. DuncanBruce WilkoffJames D. Causey, III
    • A61N1/362A61N1/365A61N1/39
    • A61N1/36514A61N1/3621A61N1/3962
    • An antitachycardia stimulation device that automatically adjusts its detection rate threshold as a function of a sensed physiological parameter indicative of cardiac rate. The implantable antitachycardia stimulation device includes heart rate detection circuitry and antitachycardia therapy circuitry for applying a specific antitachycardia therapy in the event that the detected heart rate falls within at least one tachycardia rate zone. The tachycardia rate zone is defined by a lower threshold limit, and may also be defined by an upper threshold limit if more than one rate zone is used. The lower threshold limit is automatically adjusted as a function of an independently sensed physiological parameter that predicts a normal or natural change in the heart rate. If more then one rate zone is used, other threshold limits may also be adjusted automatically as a separate function of the same sensed physiological parameter. In one embodiment of the invention, the implantable stimulation device comprises a rate-responsive pacemaker, and the sensed physiological parameter used to adjust the rate threshold limit(s) is also used to define a sensor indicated rate signal to control the pacing rate of the pacemaker.
    • 一种抗心动过速刺激装置,其自动调整其检测率阈值作为指示心率的感测生理参数的函数。 可植入的抗心动过速刺激装置包括心率检测电路和用于在检测到的心率落入至少一个心动过速率区域的情况下应用特异性抗心动过速治疗的抗心动过速治疗电路。 心动过速速率区域由较低的阈值限制定义,如果使用多个速率区域,也可以通过上限阈值来定义。 根据预测心率正常或自然变化的独立感知的生理参数的函数自动调整下限阈值。 如果使用多于一个速率区域,则其他阈值限制也可以被自动调整为相同感测生理参数的分离函数。 在本发明的一个实施例中,可植入刺激装置包括速率响应起搏器,并且用于调整速率阈值极限的感测生理参数也用于定义传感器指示的速率信号,以控制起搏速率 起搏器。
    • 19. 发明授权
    • Adaptive refractory period within implantable cardioverter-defibrillator
    • 植入式心律转复除颤器内适应性不适期
    • US5470342A
    • 1995-11-28
    • US226787
    • 1994-04-12
    • Brian M. MannJames D. Causey, III
    • Brian M. MannJames D. Causey, III
    • A61N1/39
    • A61N1/3962
    • An implantable cardioverter-defibrillator (ICD) adaptively adjusts the refractory period and sensitivity setting of its sensing channel in order to optimally detect depolarization signals indicative of intrinsic cardiac rhythm or tachycardias, or depolarization signals indicative of fibrillation. In one embodiment, the ICD utilizes first and second depolarization signal processing channels, each having first and second refractory periods and first and second sensitivity settings, respectively. The sensitivity settings of the first processing channel are adaptively adjusted to sense normal depolarization signals and tachycardias. The sensitivity settings of the second processing channel are adaptively adjusted to sense fibrillation. Both the first and second refractory periods begin following either a paced depolarization or a sensed depolarization.
    • 植入式心脏复律除颤器(ICD)自适应地调节其感测通道的不适期和灵敏度设置,以便最佳地检测指示内在心律或心动过速的去极化信号,或指示原纤化的去极化信号。 在一个实施例中,ICD利用第一和第二去极化信号处理通道,每个信号处理通道分别具有第一和第二不适周期以及第一和第二灵敏度设置。 自适应地调整第一处理通道的灵敏度设置以感测正常去极化信号和心动过速。 自适应地调整第二处理通道的灵敏度设置以感测原纤维化。 第一和第二不应期都开始跟随起搏去极化或感觉去极化。