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11. 发明授权

US08591425B2 Pulse detection using patient physiological signals 有权
公开(公告)号：US08591425B2
公开(公告)日：2013-11-26
申请号：US13279048
申请日：2011-10-21
申请人： James M. Owen , Cynthia P. Jayne , William E. Crone
发明人： James M. Owen , Cynthia P. Jayne , William E. Crone
IPC分类号： A61B5/02
CPC分类号： A61N1/36557 , A61B5/0059 , A61B5/02 , A61B5/0205 , A61B5/02108 , A61B5/02416 , A61B5/02427 , A61B5/082 , A61B5/4836 , A61B5/4848 , A61B5/746 , A61B8/06 , A61B8/488 , A61N1/3625 , A61N1/365 , A61N1/39 , A61N1/3987
摘要： The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates optical characteristics of light transmitted into a patient to ascertain physiological signals, such as pulsatile changes in general blood volume proximate a light detector module. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.

12. 发明授权

US08202268B1 Method and multiple-mode device for high-power short-pulse laser ablation and CW cauterization of bodily tissues 有权
标题翻译：用于大功率短脉冲激光烧蚀和身体组织连续烧灼的方法和多模器件
公开(公告)号：US08202268B1
公开(公告)日：2012-06-19
申请号：US12050937
申请日：2008-03-18
申请人： Jonathon D. Wells , Mark P. Bendett , Matthias P. Savage-Leuchs , James M. Owen
发明人： Jonathon D. Wells , Mark P. Bendett , Matthias P. Savage-Leuchs , James M. Owen
IPC分类号： A61B18/20
CPC分类号： A61B18/22 , A61B2018/00488 , A61B2018/00494 , A61B2018/00517 , A61B2018/00577 , A61B2018/00589 , A61B2018/00595 , A61B2018/00922 , A61B2018/00958
摘要： An apparatus and process using a high-power, short-pulsed thulium laser to output infrared laser pulses delivered through an optical fiber, for cutting and ablating biological tissue. In some embodiments, the pulse length is shortened sufficiently to keep inside the stress-confined ablation region of operation. In some embodiments, the pulse is shortened to near the stress-confined ablation region of operation, while being slightly in the thermal-constrained region of operation. In some embodiments, the laser is coupled to a small low —OH optical fiber (˜100 μm diameter). In some embodiments, the device has a pulse duration of about 100 ns for efficient ablation; however in some embodiments, this parameter is adjustable.
摘要翻译：一种使用大功率短脉冲ium激光器输出通过光纤传送的红外激光脉冲，用于切割和消融生物组织的装置和过程。在一些实施例中，脉冲长度被充分地缩短以保持在应力限制的消融操作区域内。在一些实施例中，脉冲被缩短到接近应力限制的消融操作区域，同时在热约束的操作区域中略微。在一些实施例中，激光器耦合到小的低-OH光纤（〜100μm直径）。在一些实施例中，器件具有大约100ns的脉冲持续时间以用于有效的消融; 然而，在一些实施例中，该参数是可调整的。

13. 发明申请

US20110236867A1 PROMPTING SYSTEM FOR CPR DELIVERY 审中-公开
标题翻译： CPR交付提供系统
公开(公告)号：US20110236867A1
公开(公告)日：2011-09-29
申请号：US13105768
申请日：2011-05-11
申请人： Ronald E. Stickney , Robert E. Smith , James M. Owen , Alidene Doherty
发明人： Ronald E. Stickney , Robert E. Smith , James M. Owen , Alidene Doherty
IPC分类号： G09B23/28
CPC分类号： G09B23/288 , A61B5/046 , A61B5/0535 , A61B5/742 , A61N1/39 , A61N1/3993
摘要： A method of providing instruction on the performance of chest compressions includes providing a series of signals of a first type corresponding to the desired rhythm of delivery of chest compressions in a chest compression series, and providing signals of a second type which indicate a desired point in the first series. The desired point may be a point near the end of the chest compression series. The signals of the second type may be a voiced countdown to the end of the compression series. The signals of the first type may be a series of identical sounds delivered in the desired rhythm for chest compressions, and the signals of the second type may be sounds distinct from those of the first type which correspond to the rhythm of the last N compressions in the series. The desired point in the first series may include a first point at a desired interval from the first compression, where the interval is measured in number of compressions or elapsed time. A protocol may be chosen between a protocol for a patient with a secured airway and one for a patient with an unsecured airway.
摘要翻译：提供关于胸部按压的表现的指导的方法包括提供与胸部按压序列中胸部按压的期望节奏对应的第一类型的一系列信号，以及提供第二类型的信号，其指示所需的点第一个系列。所需要的点可以是接近胸部压缩系列末端的点。第二类型的信号可以是压缩序列结束时的有声倒计时。第一类型的信号可以是用于胸部按压的期望节奏中递送的一系列相同的声音，并且第二类型的信号可以是与第一类型的声音不同的声音，其对应于最后N次按压的节奏该系列。第一系列中的期望点可以包括以第一压缩的期望间隔的第一点，其中间隔以压缩次数或经过的时间被测量。在具有安全气道的患者的协议之间可以选择协议，一个用于具有不安全气道的患者。

14. 发明授权

US06374138B1 Defibrillation system 有权
标题翻译：除颤系统
公开(公告)号：US06374138B1
公开(公告)日：2002-04-16
申请号：US09652329
申请日：2000-08-31
申请人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
发明人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
IPC分类号： A61N139
CPC分类号： A61N1/3993 , A61N1/0452 , A61N1/0456 , A61N1/046 , A61N1/0468 , A61N1/0472 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/39 , A61N1/3918 , A61N1/3925 , A61N1/3937 , A61N1/3987
摘要： A method of treating a patient for ventricular tachycardia using a wearable defibrillator includes monitoring the patient for a predetermined condition via one or more electrodes on the defibrillator, sending a message to the patient in response to the predetermined condition, activating the defibrillator so that the defibrillator delivers defibrillation energy to the patient, and storing at least one of the results of the monitoring, sending and activating steps in a memory on the defibrillator. The method also includes downloading information stored in the memory of the defibrillator to a base station having an external interface, and transmitting the information downloaded from the memory of the base station to an external location via the external interface of the base station.
摘要翻译：使用可穿戴除颤器治疗患者心室性心动过速的方法包括通过去纤维性颤动器上的一个或多个电极监测患者的预定状况，响应于预定条件向患者发送消息，激活除颤器，使除颤器向患者提供除颤能量，并将监测，发送和激活步骤的结果中的至少一个存储在除颤器上的存储器中。该方法还包括将存储在除颤器的存储器中的信息下载到具有外部接口的基站，并且经由基站的外部接口将从基站的存储器下载的信息发送到外部位置。

15. 发明授权

US06304780B1 External defibrillator system with diagnostic module 有权
标题翻译：外部除颤器系统带诊断模块
公开(公告)号：US06304780B1
公开(公告)日：2001-10-16
申请号：US09653174
申请日：2000-08-31
申请人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
发明人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
IPC分类号： A61N139
CPC分类号： A61N1/3993 , A61N1/0452 , A61N1/0456 , A61N1/046 , A61N1/0468 , A61N1/0472 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/39 , A61N1/3918 , A61N1/3925 , A61N1/3937 , A61N1/3987
摘要： A method of treating a patient for ventricular tachycardia using a wearable defibrillator includes monitoring the patient for a predetermined condition via one or more electrodes on the defibrillator, sending a message to the patient in response to the predetermined condition, activating the defibrillator so that the defibrillator delivers defibrillation energy to the patient, and storing at least one of the results of the monitoring, sending and activating steps in a memory on the defibrillator. The method also includes downloading information stored in the memory of the defibrillator to a base station having an external interface, and transmitting the information downloaded from the memory of the base station to an external location via the external interface of the base station.
摘要翻译：使用可穿戴除颤器治疗患者心室性心动过速的方法包括通过去纤维性颤动器上的一个或多个电极监测患者的预定状况，响应于预定条件向患者发送消息，激活除颤器，使除颤器向患者提供除颤能量，并将监测，发送和激活步骤的结果中的至少一个存储在除颤器上的存储器中。该方法还包括将存储在除颤器的存储器中的信息下载到具有外部接口的基站，并且经由基站的外部接口将从基站的存储器下载的信息发送到外部位置。

16. 发明授权

US09061135B1 Apparatus and method for managing chronic pain with infrared and low-level light sources 有权
标题翻译：用红外和低级光源管理慢性疼痛的装置和方法
公开(公告)号：US09061135B1
公开(公告)日：2015-06-23
申请号：US13234102
申请日：2011-09-15
申请人： Matthew D. Keller , James M. Owen , Shuming Yuan
发明人： Matthew D. Keller , James M. Owen , Shuming Yuan
IPC分类号： A61N5/06 , A61N1/05
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0551 , A61N1/056 , A61N1/36017 , A61N1/3605 , A61N1/36071 , A61N5/0601 , A61N5/0622 , A61N5/0625 , A61N2005/0659 , A61N2005/067
摘要： Method and apparatus for infrared-light nerve stimulation plus low-level light therapy (INS-plus-LLLT) that includes providing an infrared-light nerve stimulation plus low-level light therapy (INS-plus-LLLT) device; implanting the INS-plus-LLLT device in the animal; emitting a plurality of infrared laser-light nerve-stimulation signals from the INS-plus-LLLT device and directing the plurality of infrared laser-light nerve stimulation signals toward a neural tissue of the animal in order to trigger an action potential response in the neural tissue; and generating a plurality of low-level light therapy signals using the INS-plus-LLLT device and directing the low-level light therapy signals toward the neural tissue of the animal, wherein the low-level light therapy signals are configured to be efficacious for pain management in order to reduce an acute pain of the animal.
摘要翻译：包括提供红外光神经刺激加低级光疗（INS-plus-LLLT）装置的红外光神经刺激加低级光疗法（INS-plus-LLLT）的方法和装置; 在动物体内植入INS-plus-LLLT装置; 从INS-plus-LLLT装置发射多个红外激光神经刺激信号，并将多个红外激光神经刺激信号引导到动物的神经组织，以触发神经中的动作电位响应组织; 以及使用所述INS-plus-LLLT装置产生多个低级光疗信号，并将所述低级光疗信号引向所述动物的神经组织，其中所述低级光疗信号被配置为对疼痛管理，以减少动物的急性疼痛。

17. 发明授权

US08792978B2 Laser-based nerve stimulators for, E.G., hearing restoration in cochlear prostheses and method 有权
标题翻译：基于激光的神经刺激器，E.G.，耳蜗矫形器中的听力恢复和方法
公开(公告)号：US08792978B2
公开(公告)日：2014-07-29
申请号：US12890602
申请日：2010-09-24
申请人： Jonathon D. Wells , Andrew Xing , Mark P. Bendett , Matthew D. Keller , Bryan J. Norton , James M. Owen , Shuming Yuan , Robert W. Royse , Charles A. Lemaire
发明人： Jonathon D. Wells , Andrew Xing , Mark P. Bendett , Matthew D. Keller , Bryan J. Norton , James M. Owen , Shuming Yuan , Robert W. Royse , Charles A. Lemaire
IPC分类号： A61N1/08 , A61N1/36 , A61N5/06 , A61N1/05 , A61N5/067
CPC分类号： A61N5/0613 , A61N1/0541 , A61N1/36036 , A61N1/361 , A61N5/0601 , A61N5/0603 , A61N5/0622 , A61N2005/005 , A61N2005/0605 , A61N2005/063 , A61N2005/0631 , A61N2005/0652 , A61N2005/0659 , A61N2005/0665 , A61N2005/0666 , A61N2005/067
摘要： Apparatus and method for optical- or optical-and-electrical stimulation of e.g., auditory nerve pathways, for example spiral ganglion in the cochlea or neurons in the cochlear nerve. Several configurations for guiding and directing the optical stimulation are disclosed. Several configurations for guiding and directing the electrical field (used in some embodiments, for sensitization) in and through the destination tissue to which the optical stimulation is directed are disclosed. In some embodiments, and array of IR VCSELs emit stimulation light, in particular to tissue in the cochlea for restoring hearing. In some embodiments, an electrical signal is also applied in a manner that reduces the amount of light in a pulse that is otherwise needed to elicit a NAP. In some embodiments, a heat dissipater is used to spread the heat generated by operation of the lasers and their circuits, to avoid heat damage to the tissue.
摘要翻译：用于例如听觉神经通路的光学或光学和电学刺激的装置和方法，例如耳蜗中的螺旋神经节或耳蜗神经中的神经元。公开了用于引导和引导光刺激的几种配置。公开了用于引导和引导在光刺激所指向的目的地组织中的电场（用于一些实施例中用于敏化）的几种配置。在一些实施例中，并且IR VCSEL的阵列发射刺激光，特别是耳蜗中的组织以恢复听觉。在一些实施例中，电信号也以减少另外需要引导NAP的脉冲中的光量的方式施加。在一些实施例中，散热器用于扩散由激光器及其电路的操作产生的热量，以避免对组织的热损伤。

18. 发明申请

US20100094365A9 Method and system for responding to non-perfusing and non-shockable heart rhythms 有权
标题翻译：用于应对非灌注和不可震荡心律的方法和系统
公开(公告)号：US20100094365A9
公开(公告)日：2010-04-15
申请号：US11591194
申请日：2006-10-31
申请人： Robert G. Walker , James M. Owen
发明人： Robert G. Walker , James M. Owen
IPC分类号： A61N1/18
CPC分类号： A61N1/3925 , A61B5/0464
摘要： A system and method are disclosed for prompting emergency medical personnel who are attending to a patient. When the patient presents a heart rhythm that is a non-perfusing and non-shockable rhythm or perfusing but unstable, the attending personnel are prompted to administer therapy, such as reestablishing perfusion by performing CPR. The attending personnel may also be urged to defer taking the pulse of the patient.
摘要翻译：公开了一种系统和方法，用于促使正在接受病人的紧急医务人员。当患者出现心跳不节律或不可撼动的节律或灌注但不稳定时，会引导参加人员进行治疗，如通过进行CPR重建灌注。也可以督促出席人员延期服用患者的脉搏。

19. 发明授权

US06944498B2 Method of utilizing an external defibrillator by replacing its electrodes 有权
标题翻译：通过更换其电极来利用外部除颤器的方法
公开(公告)号：US06944498B2
公开(公告)日：2005-09-13
申请号：US10235171
申请日：2002-09-05
申请人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
发明人： James M. Owen , Randall W. Fincke , James P. O'Leary , Mark H. Totman
IPC分类号： A61N1/04 , A61N1/39
CPC分类号： A61N1/3993 , A61N1/0452 , A61N1/0456 , A61N1/046 , A61N1/0468 , A61N1/0472 , A61N1/0476 , A61N1/0492 , A61N1/0496 , A61N1/39 , A61N1/3918 , A61N1/3925 , A61N1/3937 , A61N1/3987
摘要： A method of treating a patient for ventricular tachycardia using a wearable defibrillator includes monitoring the patient for a predetermined condition via one or more electrodes on the defibrillator, sending a message to the patient in response to the predetermined condition, activating the defibrillator so that the defibrillator delivers defibrillation energy to the patient, and storing at least one of the results of the monitoring, sending and activating steps in a memory on the defibrillator. The method also includes downloading information stored in the memory of the defibrillator to a base station having an external interface, and transmitting the information downloaded from the memory of the base station to an external location via the external interface of the base station.
摘要翻译：使用可穿戴除颤器治疗患者心室性心动过速的方法包括通过去纤维性颤动器上的一个或多个电极监测患者的预定状况，响应于预定条件向患者发送消息，激活除颤器，使除颤器向患者提供除颤能量，并将监测，发送和激活步骤的结果中的至少一个存储在除颤器上的存储器中。该方法还包括将存储在除颤器的存储器中的信息下载到具有外部接口的基站，并且经由基站的外部接口将从基站的存储器下载的信息发送到外部位置。

20. 发明授权

US08992432B2 Pulse detection using patient physiological signals 有权
公开(公告)号：US08992432B2
公开(公告)日：2015-03-31
申请号：US13279030
申请日：2011-10-21
申请人： James M. Owen , Cynthia P. Jayne , William E. Crone
发明人： James M. Owen , Cynthia P. Jayne , William E. Crone
IPC分类号： A61B5/02 , A61N1/39 , A61B5/024 , A61B5/0205 , A61N1/365
CPC分类号： A61N1/36557 , A61B5/0059 , A61B5/02 , A61B5/0205 , A61B5/02108 , A61B5/02416 , A61B5/02427 , A61B5/082 , A61B5/4836 , A61B5/4848 , A61B5/746 , A61B8/06 , A61B8/488 , A61N1/3625 , A61N1/365 , A61N1/39 , A61N1/3987
摘要： The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates optical characteristics of light transmitted into a patient to ascertain physiological signals, such as pulsatile changes in general blood volume proximate a light detector module. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.

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