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11. 发明授权

US5256647A Compositions comprising 1-substituted azacycloalkanes 失效
标题翻译：包含1-取代的氮杂环烷烃的组合物
公开(公告)号：US5256647A
公开(公告)日：1993-10-26
申请号：US611612
申请日：1990-11-13
申请人： Gevork Minaskanian , James V. Peck , Eric L. Nelson
发明人： Gevork Minaskanian , James V. Peck , Eric L. Nelson
IPC分类号： A01N25/02 , A01N43/36 , A01N43/40 , A01N43/62 , A61K9/00 , A61K47/22 , B01J31/02 , C05G3/00 , C07D223/10 , D06P1/642 , A01N43/04 , A61K7/42 , A61K7/44 , A61K9/02 , A61K9/06 , A61K9/10 , A61K9/12 , A61K31/70
CPC分类号： A61K9/0014 , A01N25/02 , A01N43/36 , A01N43/40 , A01N43/62 , A61K47/22 , C05G3/00 , C07D223/10 , D06P1/6426 , Y10S424/05 , Y10S424/10 , Y10S424/13 , Y10S514/844 , Y10S514/846 , Y10S514/858 , Y10S514/859 , Y10S514/861 , Y10S514/862 , Y10S514/863 , Y10S514/864 , Y10S514/88
摘要： This invention provides compositions comprising a physiologically-active agent and a compound having the structural formula ##STR1## wherein X may represent sulfur or two hydrogen atoms; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n is 0-18 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen, in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.
摘要翻译：本发明提供了包含生理活性剂和具有结构式的化合物的组合物，其中X可以表示硫或两个氢原子; R'是H或具有1-4个碳原子的低级烷基; m为2-6; n是0-18，R是-CH 3，或者，其中R“是H或卤素，其量可以有效地增强生理活性剂通过身体的皮肤或其他膜的渗透的动物

12. 发明授权

US4917688A Bandage for transdermal delivery of systemically-active drug 失效
标题翻译：用于经皮递送系统活性药物的绷带
公开(公告)号：US4917688A
公开(公告)日：1990-04-17
申请号：US211833
申请日：1988-06-27
申请人： Eric L. Nelson , Rajaram Vaidyanathan
发明人： Eric L. Nelson , Rajaram Vaidyanathan
IPC分类号： A61F13/02 , A61K9/70
CPC分类号： A61K9/703 , A61F13/00063 , A61F13/0226 , A61F13/0246 , A61F13/0259 , A61K9/7084
摘要： A transdermal delivery bandage and system is provided which includes a supply of topically and/or systemically-active drug, an adhesive for releasably securing the bandage to a dermal surface and control means which are separate from the supply of topical and/or systemically-active drug for adjustably controlling surface contact area between the topical and/or systemically-active drug and the dermal surface. The control means are manually operable by a user of the bandage for adjustably controlling the dose of drug to be administered. Alternatively, the maximum available dose from a given bandage may be preselected by a dispensing pharmacist.
摘要翻译：提供透皮递送绷带和系统，其包括局部和/或全身活性药物的供应，用于将绷带可释放地固定到皮肤表面的粘合剂和与局部和/或系统活性的供应分开的控制装置可调节地控制局部和/或全身活性药物与皮肤表面之间的表面接触面积的药物。控制装置可由绷带的使用者手动操作，以可调节地控制待施用的药物的剂量。或者，来自给定绷带的最大可用剂量可以由配药药剂师预先选择。

13. 发明授权

US4316888A Method and composition of reducing pain 失效
标题翻译：减轻疼痛的方法和组成
公开(公告)号：US4316888A
公开(公告)日：1982-02-23
申请号：US140493
申请日：1980-04-15
申请人： Eric L. Nelson
发明人： Eric L. Nelson
IPC分类号： C07D221/28 , A61K31/47 , A61K31/485 , A61K33/06 , A61P25/04 , A61K33/00 , A61K33/08 , A61K33/10
CPC分类号： A61K33/06 , A61K31/485
摘要： A method for temporarily reducing pain in animals including humans, and especially pain associated with gastrointestinal dysfunction, by administering to an animal having pain an effective, pain reducing amount of dextromethorphan, preferably as the hydrobromide.
摘要翻译：通过对具有疼痛的动物施用有效的减少疼痛的右美沙芬的量，优选作为氢溴酸盐，暂时减少包括人在内的动物的疼痛，特别是与胃肠功能障碍相关的疼痛的方法。

14. 发明授权

US4310525A Method of treatment of inflammation 失效
标题翻译：治疗炎症的方法
公开(公告)号：US4310525A
公开(公告)日：1982-01-12
申请号：US227628
申请日：1981-01-23
申请人： Eric L. Nelson
发明人： Eric L. Nelson
IPC分类号： A61K31/55 , A61P29/00 , C07D223/10 , C07D233/10 , A61K31/33
CPC分类号： A61K31/55 , C07D223/10
摘要： There is disclosed a method of treatment of inflammation in humans and animals comprising contacting the inflamed area with an effective, anti-inflammatory amount of 1-dodecylazacycloheptan-2-one.
摘要翻译：公开了一种治疗人和动物炎症的方法，包括使发炎区域与有效的抗炎量的1-十二烷基氮杂环庚烷-2-酮接触。

15. 发明授权

US07738252B2 Method and apparatus for thermal management of computer memory modules 有权
标题翻译：计算机内存模块热管理方法和装置
公开(公告)号：US07738252B2
公开(公告)日：2010-06-15
申请号：US11621396
申请日：2007-01-09
申请人： Franz Michael Schuette , Ryan M. Petersen , Eric L. Nelson , Bhulinder Sethi
发明人： Franz Michael Schuette , Ryan M. Petersen , Eric L. Nelson , Bhulinder Sethi
IPC分类号： H05K7/20 , G06F1/20
CPC分类号： G06F1/206
摘要： A heat spreader and method for thermal management of a computer memory module by promoting natural convection cooling of the memory module. The heat spreader includes a frame surrounding a planar body adapted to be mounted to a memory module of a computer, and a grid defined in the planar body by a plurality of uniformly distributed perforations. The perforations extend through the planar body to allow natural convention between an interior space beneath the planar body and an exterior space above the planar body.
摘要翻译：一种用于通过促进存储器模块的自然对流冷却来对计算机存储器模块进行热管理的散热器和方法。散热器包括围绕适于安装到计算机的存储器模块的平面主体的框架，以及通过多个均匀分布的穿孔限定在平面主体中的格栅。穿孔延伸穿过平面体，以允许平面体下面的内部空间与平面体上方的外部空间之间的自然约定。

16. 发明授权

US06473899B1 Field configurable embedded computer system 有权
标题翻译：现场可配置嵌入式计算机系统
公开(公告)号：US06473899B1
公开(公告)日：2002-10-29
申请号：US09327410
申请日：1999-06-07
申请人： Eric L. Nelson , Michael L. Evans , Lance N. Shelton , Jared C. Roundy
发明人： Eric L. Nelson , Michael L. Evans , Lance N. Shelton , Jared C. Roundy
IPC分类号： G06F945
CPC分类号： G06F9/4411 , G06F8/65
摘要： An apparatus and method for downloading firmware upgrades to a targeted remote field configurable embedded computer system over a computer network. The targeted device need not be disconnected from the network and requires no human intervention at the remote side. The entire firmware, including the downloading mechanism, can be updated in an efficient manner.
摘要翻译：一种用于通过计算机网络将固件升级下载到目标远程现场可配置嵌入式计算机系统的装置和方法。目标设备不需要与网络断开连接，并且不需要在远端进行人为干预。可以有效地更新整个固件，包括下载机制。

17. 发明授权

US06394343B1 System for card to card transfer of monetary values 失效
标题翻译：卡转卡系统的货币价值
公开(公告)号：US06394343B1
公开(公告)日：2002-05-28
申请号：US09418059
申请日：1999-10-14
申请人： Jon N. Berg , Eric L. Nelson
发明人： Jon N. Berg , Eric L. Nelson
IPC分类号： G06F1760
CPC分类号： G07F7/1008 , G06K7/0008 , G06K7/0021 , G06K19/04 , G06K19/0728 , G06K19/077 , G06K19/07703 , G06K19/07749 , G06Q20/3415
摘要： A smart card stores monetary values and selectively transfers monetary values to and receives monetary values from a compatible smart card. The smart card includes a data storage device that stores data representing monetary values. Control circuitry controls the transfer of the monetary values into the data storage device and controls the transfer of the monetary values out of the data storage device. A data transfer interface couples directly to a like interface on the compatible card to enable data to be transferred between the smart card and the compatible card. A system for electronic transfer of monetary values includes first and second smart cards. Each of the first and second smart cards includes a data storage device that stores data representing monetary values.
摘要翻译：智能卡存储货币价值，并选择性地将货币价值转移到兼容智能卡并从其获取货币价值。智能卡包括存储表示货币值的数据的数据存储装置。控制电路控制货币值转移到数据存储装置中并控制货币值从数据存储装置传出。数据传输接口直接耦合到兼容卡上的类似接口，以使数据能够在智能卡和兼容卡之间传输。电子货币转移系统包括第一和第二智能卡。第一和第二智能卡中的每一个包括存储表示货币值的数据的数据存储装置。

18. 发明授权

US5270346A Penetration enhancers for transdermal delivery of systemic agents 失效
标题翻译：用于透皮递送全身药物的渗透增强剂
公开(公告)号：US5270346A
公开(公告)日：1993-12-14
申请号：US973239
申请日：1992-11-06
申请人： Gevork Minaskanian , James V. Peck , Eric L. Nelson
发明人： Gevork Minaskanian , James V. Peck , Eric L. Nelson
IPC分类号： A01N25/02 , A01N43/36 , A01N43/40 , A01N43/62 , A61K9/00 , A61K47/22 , B01J31/02 , C05G3/00 , C07D223/10 , D06P1/642 , A61K9/06 , A61K9/12 , A61K31/445 , A61K31/70
CPC分类号： A61K9/0014 , A01N25/02 , A01N43/36 , A01N43/40 , A01N43/62 , A61K47/22 , C05G3/00 , C07D223/10 , D06P1/6426 , Y10S514/944 , Y10S514/969
摘要： This invention relates to a method for administering systemically active agents, including therapeutic agents, through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent a non-toxic, effective, penetrating amount of a membrane penetration enhancer having the structural formula ##STR1## wherein X represents sulfur or two hydrogen atoms; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n is 0-18 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen.
摘要翻译：本发明涉及通过透皮装置或制剂通过人和动物的皮肤或粘膜施用全身活性剂（包括治疗剂）的方法，所述方法包括与所述全身药剂局部给药无毒，有效的穿透量的具有结构式“IMAGE”的膜渗透增强剂，其中X表示硫或两个氢原子; R'是H或具有1-4个碳原子的低级烷基; m为2-6; n为0-18，R为-CH 3，其中R“为H或卤素。

19. 发明授权

US4148879A Inhibition of platelet aggregation with selected phosphonic and phosphinic acid esters 失效
标题翻译：用选择的膦酸和次膦酸酯抑制血小板聚集
公开(公告)号：US4148879A
公开(公告)日：1979-04-10
申请号：US864017
申请日：1977-12-23
申请人： Eric L. Nelson
发明人： Eric L. Nelson
IPC分类号： A61K31/66 , A61K35/14 , A61K31/685
CPC分类号： A61K31/685 , A61K31/66
摘要： A process for inhibiting platelet aggregation or thrombus formation by the addition of a member selected from the group consisting of a compound of the formula: ##STR1## WHEREIN X is an alkyl or alkenyl chain having 2-8 carbon atoms, one of which carbon atoms may be in the form of a carbonyl group, Y is H, alkyl, dialkylaminoethyl, aryl, aralkyl or aryl and aralkyl substituted with one or more R, and R is H, lower alkyl, lower alkoxy, halogen, CF.sub.3, NO.sub.2, OH, CN, COOR.sub.1, ##STR2## NHCOR.sub.1, NR.sub.1 R.sub.2 or ##STR3## where R.sub.1 and R.sub.2 are each selected from the group consisting of H and lower alkyl; R, R.sub.1 and R.sub.2 being the same or different, T is selected from the group consisting of O, NH, S and CH.sub.2 with the proviso that only one T is O, Z is 0 or 1 and n is 0-5; and pharmaceutically acceptable salts thereof, to in vivo and in vitro platelet systems.
摘要翻译：通过添加选自下列化合物的成员来抑制血小板聚集或血栓形成的方法：其中X是具有2-8个碳原子的烷基或链烯基链，其中一个碳原子可以是羰基的形式，Y是H，烷基，二烷基氨基乙基，芳基，芳烷基或芳基，被一个或多个R取代的芳烷基，R是H，低级烷基，低级烷氧基，卤素，CF 3，NO 2，OH ，CN，COOR1，NHCOR1，NR1R2或，其中R1和R2各自选自H和低级烷基; R，R 1和R 2相同或不同，T选自O，NH，S和CH 2，条件是仅一个T为O，Z为0或1，n为0-5; 和其药学上可接受的盐，用于体内和体外血小板系统。

20. 发明申请

US20100296240A1 METHOD AND APPARATUS FOR THERMAL MANAGEMENT OF COMPUTER MEMORY MODULES 审中-公开
标题翻译：计算机存储器模块热管理方法与装置
公开(公告)号：US20100296240A1
公开(公告)日：2010-11-25
申请号：US12783632
申请日：2010-05-20
申请人： Franz Michael Schuette , Ryan M. Petersen , Eric L. Nelson , Bhulinder Sethi
发明人： Franz Michael Schuette , Ryan M. Petersen , Eric L. Nelson , Bhulinder Sethi
IPC分类号： H05K7/20
CPC分类号： G06F1/206
摘要： A heat spreader and method for thermal management of a computer memory module by promoting natural convection cooling of the memory module. The heat spreader includes a frame surrounding a planar body adapted to be mounted to a memory module of a computer, and a grid defined in the planar body by a plurality of uniformly distributed perforations. The perforations extend through the planar body to allow natural convention between an interior space beneath the planar body and an exterior space above the planar body.
摘要翻译：一种用于通过促进存储器模块的自然对流冷却来对计算机存储器模块进行热管理的散热器和方法。散热器包括围绕适于安装到计算机的存储器模块的平面主体的框架，以及通过多个均匀分布的穿孔限定在平面主体中的格栅。穿孔延伸穿过平面体，以允许平面体下面的内部空间与平面体上方的外部空间之间的自然约定。

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