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11. 发明申请

US20130108013A1 SYSTEM AND METHOD FOR IMPROVED ENERGY SERIES OF IMAGES USING MULTI-ENERGY CT 有权
标题翻译：使用多功能CT改进图像能量系列的系统和方法
公开(公告)号：US20130108013A1
公开(公告)日：2013-05-02
申请号：US13809800
申请日：2011-07-18
申请人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
发明人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
IPC分类号： G06T11/00 , G01N23/04
CPC分类号： G06T11/003 , A61B6/032 , A61B6/4241 , A61B6/482 , A61B6/50 , A61B6/5205 , G01N23/046 , G01N2223/1016 , G01N2223/419 , G01N2223/423 , G06T5/20
摘要： A method for creating an energy series of images acquired using a multi-energy computed tomography (CT) imaging system having a plurality of energy bins includes acquiring, with the multi-energy CT imaging system, a series of energy data sets, where each energy data set is associated with at least one of the energy bins. The method includes producing a conglomerate image using at least a plurality of the energy data sets and, using the conglomerate image, reconstructing an energy series of images, each image in the energy series of images corresponding to at least one of the energy data sets.
摘要翻译：一种用于创建使用具有多个能量箱的多能量计算机断层摄影（CT）成像系统获取的能量系列图像的方法包括采用多能CT成像系统获取一系列能量数据集，其中每个能量数据集与至少一个能量箱相关联。该方法包括使用至少多个能量数据集生成聚集图像，并且使用该聚集图像重建能量系列的图像，能量系列图像中的每个图像对应于能量数据集中的至少一个。

12. 发明授权

US08280135B2 System and method for highly attenuating material artifact reduction in x-ray computed tomography 有权
标题翻译： X射线计算机断层扫描中高度衰减材料伪影减少的系统和方法
公开(公告)号：US08280135B2
公开(公告)日：2012-10-02
申请号：US12690765
申请日：2010-01-20
申请人： Cynthia H McCollough , Lifeng Yu
发明人： Cynthia H McCollough , Lifeng Yu
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/12 , A61B6/5258 , G06T5/005 , G06T7/13 , G06T11/005 , G06T2207/10081 , G06T2207/20036 , G06T2207/30004
摘要： The present invention is a method for reducing artifacts caused by highly attenuating materials in x-ray computed tomography (“CT”) images. The method includes combining projection views acquired at equivalent view angles to generate a projection plane data set, from which a reformatted projection is produced. The reformatted projection is then processed to detect and segment regions corresponding to objects composed of metals, metal alloys, or other highly attenuating materials. These segmented regions are then removed from the reformatted projection and the removed portions replaced by attenuation information interpolated from portions of the reformatted projection adjacent the removed portions. The interpolated reformatted projection is then mapped back to a projection plane data set, and an image of the subject is reconstructed from the projection views contained in that data set. The reconstructed image, therefore, is one in which artifacts caused by highly attenuating materials are substantially suppressed.
摘要翻译：本发明是一种减少由X射线计算机断层摄影（CT）图像中的高衰减材料引起的假象的方法。该方法包括组合以等同视角获得的投影视图，以产生投影平面数据集，从该投影平面数据集中产生重新格式化的投影。然后对重新格式化的投影进行处理以检测和分割对应于由金属，金属合金或其它高度衰减材料组成的物体的区域。然后将这些分段区域从重新格式化的突起中移除，并且将去除的部分替换为与邻近去除部分的重新格式化突起的部分内插的衰减信息。然后将内插的重新格式化的投影映射回到投影平面数据集，并且从包含在该数据集中的投影视图重建对象的图像。因此，重建的图像是其中由高度衰减的材料引起的伪像被基本抑制的图像。

13. 发明申请

US20110188725A1 METHOD FOR RECONSTRUCTION IN DUAL ENERGY, DUAL SOURCE HELICAL COMPUTED TOMOGRAPHY 有权
标题翻译：双能重建方法，双源螺旋计算机图
公开(公告)号：US20110188725A1
公开(公告)日：2011-08-04
申请号：US13059579
申请日：2009-09-02
申请人： Lifeng Yu , Cynthia H. Mccollough
发明人： Lifeng Yu , Cynthia H. Mccollough
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/408
摘要： A system and method for the accurate quantitative evaluation of dual-energy computed tomography (CT) projection data that is acquired in a dual-source helical scan includes employing a dual-source z-axis helical interpolation method. The method includes transforming the two helical projection data sets, where corresponding projections of high- and low-energy data sets are shifted with respect to one another by 90 degrees or another angle, into corresponding non-helical projection data sets. A dual-source helical interpolation algorithm allows for projection space dual-energy processing by realigning the high- and low-energy datasets based on the z-axis interpolation. This algorithm may be implemented using a variety of interpolation schemes and can be extended from single slice to multi-slice data acquisitions. Subsequent to the registration of the non-helical projection data sets, projection space processing allows for accurate material quantification and virtual monochromatic images in which beam hardening artifacts have been substantially suppressed.
摘要翻译：用于在双源螺旋扫描中获取的双能量计算机断层摄影（CT）投影数据的精确定量评估的系统和方法包括采用双源z轴螺旋插值方法。该方法包括对两个螺旋投影数据集进行变换，其中高能数据集和低能数据集的相应投影相对于彼此偏移了90度或另一个角度，转换为相应的非螺旋投影数据集。双源螺旋插值算法允许通过基于z轴插值重新对齐高能量和低能量数据集进行投影空间双能量处理。该算法可以使用各种插值方案来实现，并且可以从单片扩展到多片数据采集。在非螺旋投影数据集的注册之后，投影空间处理允许精确的材料量化和虚拟单色图像，其中束固化伪影已被基本上抑制。

14. 发明申请

US20090207967A1 SYSTEM AND METHOD FOR QUANTITATIVE IMAGING OF CHEMICAL COMPOSITION TO DECOMPOSE MULTIPLE MATERIALS 有权
标题翻译：用于定量成像化学成分以分解多种材料的系统和方法
公开(公告)号：US20090207967A1
公开(公告)日：2009-08-20
申请号：US12371433
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： H05G1/60
CPC分类号： A61B6/482 , A61B5/4869 , A61B6/032 , A61B6/4014 , A61B6/4241
摘要： The present invention provides a material decomposition method capable of determining the distribution of density and constituent material concentration throughout an imaged object. The concentration, in the form of a mass fraction, mass percent, weight fraction, or weight percent, is determined from CT images acquired at different energy levels. The ratio of attenuation coefficients associated with one energy level to attenuation coefficients associated with another energy level is determined and used as an index in a lookup table to determine the concentration of a given material throughout the imaged object.
摘要翻译：本发明提供一种能够确定整个成像对象的密度和构成材料浓度分布的材料分解方法。以不同能级获得的CT图像确定以质量分数形式的质量百分比，重量分数或重量百分比的浓度。确定与一个能级相关联的衰减系数与与另一能级相关联的衰减系数的比率，并将其用作查找表中的索引，以确定整个成像对象中给定材料的浓度。

15. 发明授权

US07885373B2 System and method for quantitative imaging of chemical composition to decompose multiple materials 有权
标题翻译：用于化学成分定量成像分解多种材料的系统和方法
公开(公告)号：US07885373B2
公开(公告)日：2011-02-08
申请号：US12371433
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： H05G1/60
CPC分类号： A61B6/482 , A61B5/4869 , A61B6/032 , A61B6/4014 , A61B6/4241
摘要： The present invention provides a material decomposition method capable of determining the distribution of density and constituent material concentration throughout an imaged object. The concentration, in the form of a mass fraction, mass percent, weight fraction, or weight percent, is determined from CT images acquired at different energy levels. The ratio of attenuation coefficients associated with one energy level to attenuation coefficients associated with another energy level is determined and used as an index in a lookup table to determine the concentration of a given material throughout the imaged object.
摘要翻译：本发明提供一种能够确定整个成像对象的密度和构成材料浓度分布的材料分解方法。以不同能级获得的CT图像确定以质量分数形式的质量百分比，重量分数或重量百分比的浓度。确定与一个能级相关联的衰减系数与与另一能级相关联的衰减系数的比率，并将其用作查找表中的索引，以确定整个成像对象中给定材料的浓度。

16. 发明申请

US20100183214A1 System and Method for Highly Attenuating Material Artifact Reduction in X-Ray Computed Tomography 有权
标题翻译： X射线计算机断层扫描中高度减弱材料人造物减少的系统和方法
公开(公告)号：US20100183214A1
公开(公告)日：2010-07-22
申请号：US12690765
申请日：2010-01-20
申请人： Cynthia H. McCollough , Lifeng Yu
发明人： Cynthia H. McCollough , Lifeng Yu
IPC分类号： G06K9/00 , H05G1/60
CPC分类号： A61B6/032 , A61B6/027 , A61B6/12 , A61B6/5258 , G06T5/005 , G06T7/13 , G06T11/005 , G06T2207/10081 , G06T2207/20036 , G06T2207/30004
摘要： The present invention is a method for reducing artifacts caused by highly attenuating materials in x-ray computed tomography (“CT”) images. The method includes combining projection views acquired at equivalent view angles to generate a projection plane data set, from which a reformatted projection is produced. The reformatted projection is then processed to detect and segment regions corresponding to objects composed of metals, metal alloys, or other highly attenuating materials. These segmented regions are then removed from the reformatted projection and the removed portions replaced by attenuation information interpolated from portions of the reformatted projection adjacent the removed portions. The interpolated reformatted projection is then mapped back to a projection plane data set, and an image of the subject is reconstructed from the projection views contained in that data set. The reconstructed image, therefore, is one in which artifacts caused by highly attenuating materials are substantially suppressed.
摘要翻译：本发明是一种减少由x射线计算机断层摄影（“CT”）图像中的高衰减材料引起的伪像的方法。该方法包括组合以等同视角获得的投影视图，以产生投影平面数据集，从该投影平面数据集中产生重新格式化的投影。然后对重新格式化的投影进行处理以检测和分割对应于由金属，金属合金或其它高度衰减材料组成的物体的区域。然后将这些分段区域从重新格式化的突起中移除，并且将去除的部分替换为与邻近去除部分的重新格式化突起的部分内插的衰减信息。然后将内插的重新格式化的投影映射回到投影平面数据集，并且从包含在该数据集中的投影视图重建对象的图像。因此，重建的图像是其中由高度衰减的材料引起的伪像被基本抑制的图像。

17. 发明授权

US08705822B2 Method for creating images indicating material decomposition in dual energy, dual source helical computed tomography 有权
标题翻译：用于创建指示双能量双源螺旋计算机断层扫描中材料分解的图像的方法
公开(公告)号：US08705822B2
公开(公告)日：2014-04-22
申请号：US13059579
申请日：2009-09-02
申请人： Lifeng Yu , Cynthia H. McCollough
发明人： Lifeng Yu , Cynthia H. McCollough
IPC分类号： G06T11/00 , G01N29/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/408
摘要： A system and method for the accurate quantitative evaluation of dual-energy computed tomography (CT) projection data that is acquired in a dual-source helical scan includes employing a dual-source z-axis helical interpolation method. The method includes transforming the two helical projection data sets, where corresponding projections of high- and low-energy data sets are shifted with respect to one another by 90 degrees or another angle, into corresponding non-helical projection data sets. A dual-source helical interpolation algorithm allows for projection space dual-energy processing by realigning the high- and low-energy datasets based on the z-axis interpolation. This algorithm may be implemented using a variety of interpolation schemes and can be extended from single slice to multi-slice data acquisitions. Subsequent to the registration of the non-helical projection data sets, projection space processing allows for accurate material quantification and virtual monochromatic images in which beam hardening artifacts have been substantially suppressed.
摘要翻译：用于在双源螺旋扫描中获取的双能量计算机断层摄影（CT）投影数据的精确定量评估的系统和方法包括采用双源z轴螺旋插值方法。该方法包括对两个螺旋投影数据集进行变换，其中高能数据集和低能数据集的相应投影相对于彼此偏移了90度或另一个角度，转换为相应的非螺旋投影数据集。双源螺旋插值算法允许通过基于z轴插值重新对齐高能量和低能量数据集进行投影空间双能量处理。该算法可以使用各种插值方案来实现，并且可以从单片扩展到多片数据采集。在非螺旋投影数据集的注册之后，投影空间处理允许精确的材料量化和虚拟单色图像，其中束固化伪影已被基本上抑制。

18. 发明授权

US08290232B2 System and method for quantitative imaging of chemical composition to decompose more than two materials 有权
标题翻译：用于化学成分定量成像分解两种以上材料的系统和方法
公开(公告)号：US08290232B2
公开(公告)日：2012-10-16
申请号：US12371425
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： G06K9/00
CPC分类号： G01N23/046 , A61B6/032 , A61B6/4014 , A61B6/4241 , A61B6/482 , G01N2223/419 , G01N2223/423
摘要： A system and method for decomposing more than two materials in an imaging object includes performing a CT imaging acquisition of a portion of an imaging object using at least two energy levels to acquire imaging data associated with each of the at least two energy levels. A total mass attenuation of the imaging data is expressed as a weighted sum of constituent element mass attenuation coefficients and an effective atomic number and density of the constituent elements in the portion of the imaging object is determined by one of a number of methods. Accordingly, concentration of the constituent elements in imaged object is determined by solve the expression using known material attenuation coefficients and the measured CT data.
摘要翻译：用于在成像对象中分解两种以上材料的系统和方法包括使用至少两个能级来执行对成像对象的一部分的CT成像采集，以获取与所述至少两个能级中的每一个相关联的成像数据。成像数据的总质量衰减表示为构成元素质量衰减系数的加权和，并且成像对象的该部分中的组成元素的有效原子数和密度由多种方法之一确定。因此，通过使用已知材料衰减系数和测量的CT数据求解表达式来确定成像对象中的组成元素的浓度。

19. 发明授权

US07801265B2 System and method for creating mixed image from dual-energy CT data 有权
标题翻译：用于从双能CT数据创建混合图像的系统和方法
公开(公告)号：US07801265B2
公开(公告)日：2010-09-21
申请号：US12276501
申请日：2008-11-24
申请人： Lifeng Yu , Cynthia H. McCollough
发明人： Lifeng Yu , Cynthia H. McCollough
IPC分类号： A61B6/00
CPC分类号： A61B6/405 , A61B6/032 , A61B6/482 , A61B6/5235
摘要： A system and method for creating a combined or mixed-energy image using both low- and high-energy CT data sets acquired using a dual-energy CT system. The low- and high-energy datasets are mixed using desired weighting factors to mimic a “single-energy” image. The low-energy dataset provides data with improved contrast enhancement, but with increased noise level. The high-energy dataset provides data with lower contrast enhancement, but with better noise properties. By combining the low- and high-energy datasets in accordance with the present method, the resulting mixed-energy images utilize the information of full dose of radiation used in the dual-energy scan. A plurality of weighting metrics can be selected, including patient size, dose partitioning, or image quality, to determine the desired weighting factors based on the weighting metrics. By selecting the proper weight factors, image noise can be reduced and/or the contrast to noise ratio can be increased in the mixed-energy image.
摘要翻译：一种使用双能量CT系统获得的使用低能量和高能量CT数据集创建组合或混合能量图像的系统和方法。低能量和高能量数据集使用所需的加权因子进行混合，以模拟“单能量”图像。低能量数据集为数据提供了改进的对比度增强，但噪声水平提高。高能数据集提供的数据具有较低的对比度增强，但噪声性能更好。通过根据本方法组合低能量和高能量数据集，所得到的混合能量图像利用在双能量扫描中使用的全剂量辐射的信息。可以选择多个加权度量，包括患者大小，剂量分配或图像质量，以基于加权度量确定期望的加权因子。通过选择适当的重量因子，在混合能量图像中可以降低图像噪声和/或对比度噪声比。

20. 发明申请

US20090208084A1 SYSTEM AND METHOD FOR QUANTITATIVE IMAGING OF CHEMICAL COMPOSITION TO DECOMPOSE MORE THAN TWO MATERIALS 有权
标题翻译：用于量化成像化学成分的系统和方法，用于分解多于两种材料
公开(公告)号：US20090208084A1
公开(公告)日：2009-08-20
申请号：US12371425
申请日：2009-02-13
申请人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
发明人： Xin Liu , Lifeng Yu , Cynthia H. McCollough
IPC分类号： G06K9/00
CPC分类号： G01N23/046 , A61B6/032 , A61B6/4014 , A61B6/4241 , A61B6/482 , G01N2223/419 , G01N2223/423
摘要： A system and method for decomposing more than two materials in an imaging object includes performing a CT imaging acquisition of a portion of an imaging object using at least two energy levels to acquire imaging data associated with each of the at least two energy levels. A total mass attenuation of the imaging data is expressed as a weighted sum of constituent element mass attenuation coefficients and an effective atomic number and density of the constituent elements in the portion of the imaging object is determined by one of a number of methods. Accordingly, concentration of the constituent elements in imaged object is determined by solve the expression using known material attenuation coefficients and the measured CT data.
摘要翻译：用于在成像对象中分解两种以上材料的系统和方法包括使用至少两个能级来执行对成像对象的一部分的CT成像采集，以获取与所述至少两个能级中的每一个相关联的成像数据。成像数据的总质量衰减表示为构成元素质量衰减系数的加权和，并且成像对象的该部分中的组成元素的有效原子数和密度由多种方法之一确定。因此，通过使用已知材料衰减系数和测量的CT数据求解表达式来确定成像对象中的组成元素的浓度。

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