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11. 发明申请

US20120163557A1 METHODS AND PHANTOMS FOR CALIBRATING AN IMAGING SYSTEM 审中-公开
标题翻译：用于校准成像系统的方法和方法
公开(公告)号：US20120163557A1
公开(公告)日：2012-06-28
申请号：US12977400
申请日：2010-12-23
申请人： Jiang Hsieh , Naveen Stephan Chandra , Xiaoye Wu , Suresh Narayanan , Dan Xu , Meghan Lynn Yue
发明人： Jiang Hsieh , Naveen Stephan Chandra , Xiaoye Wu , Suresh Narayanan , Dan Xu , Meghan Lynn Yue
IPC分类号： G01D18/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/583
摘要： A method for calibrating a medical imaging system includes performing an initial calibration of the imaging system, at a manufacturing site fabricating the imaging system, using a plurality of phantoms, shipping one of the phantoms to an installation site installing the imaging system, and performing a final calibration, at an installation site of the imaging system, using the shipped phantom. A set of calibration phantoms is also described herein.
摘要翻译：用于校准医学成像系统的方法包括在制造成像系统的制造现场使用多个幻影来执行成像系统的初始校准，将一个幻影运送到安装成像系统的安装地点，以及执行在成像系统的安装地点使用运送的幻影进行最终校准。本文还描述了一组校准模体。

12. 发明授权

US08315352B2 System and method of spectral calibration and basis material decomposition for X-ray CT systems 有权
标题翻译： X射线CT系统的光谱校准和基材分解的系统和方法
公开(公告)号：US08315352B2
公开(公告)日：2012-11-20
申请号：US12883631
申请日：2010-09-16
申请人： Xiaoye Wu , Dan Xu , Naveen Chandra , Zhanyu Ge , Jiang Hsieh , Daniel David Harrison , Mary Sue Kulpins
发明人： Xiaoye Wu , Dan Xu , Naveen Chandra , Zhanyu Ge , Jiang Hsieh , Daniel David Harrison , Mary Sue Kulpins
IPC分类号： A61B6/00 , H05G1/64 , G06K9/00
CPC分类号： A61B6/583 , A61B6/032 , A61B6/482 , A61B6/585
摘要： An imaging system includes an x-ray source that emits a beam of x-rays toward an object, a detector that receives high frequency electromagnetic energy attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to compute detector coefficients based on a static low kVp measurement and a static high kVp measurement, capture incident spectra at high and low kVp during fast kVp switching, compute effective X-ray incident spectra at high and low kVp during fast kVp switching using the captured incident spectra, scan a water phantom and normalize the computed detector coefficients to water, adjust the computed effective X-ray incident spectra based on the normalized detector coefficients, compute basis material decomposition functions using the adjusted X-ray incident spectra, and generate one or more basis material density images using the computed basis material decomposition functions.
摘要翻译：成像系统包括：x射线源，其朝向物体发射X射线束;接收被物体衰减的高频电磁能的检测器;可操作地连接到检测器的数据采集系统（DAS）;以及计算机可操作地连接到DAS。计算机被编程为基于静态低kVp测量和静态高kVp测量来计算检测器系数，在快速kVp切换期间在高和低kVp处捕获入射光谱，在快速kVp期间计算高和低kVp处的有效X射线入射光谱使用捕获的入射光谱切换，扫描水体模型并将计算的检测器系数归一化为水，基于归一化的检测器系数调整计算的有效X射线入射光谱，使用调整的X射线入射光谱计算基础材料分解函数，并使用所计算的基础材料分解函数生成一个或多个基础材料密度图像。

13. 发明授权

US09135728B2 System and method for multi-energy computed tomography imaging 有权
标题翻译：多能计算机断层成像系统和方法
公开(公告)号：US09135728B2
公开(公告)日：2015-09-15
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： G06T11/00 , A61B6/06 , A61B6/00 , G21K1/02 , A61B6/03 , G21K1/10 , H01J35/26 , H01J35/30
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

14. 发明申请

US20130266115A1 SYSTEM AND METHOD FOR MULTI-ENERGY COMPUTED TOMOGRAPHY IMAGING 有权
标题翻译：多功能计算机图像成像系统与方法
公开(公告)号：US20130266115A1
公开(公告)日：2013-10-10
申请号：US13439245
申请日：2012-04-04
申请人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
发明人： Jiahua Fan , Jiang Hsieh , Naveen Chandra , Suresh Narayanan Narayanan , Dan Xu
IPC分类号： A61B6/08 , A61B6/03
CPC分类号： G06T11/005 , A61B6/032 , A61B6/06 , A61B6/4021 , A61B6/4035 , A61B6/4241 , A61B6/4291 , A61B6/482 , A61B6/582 , G06T2211/408 , G21K1/025 , G21K1/10 , H01J35/26 , H01J35/30
摘要： A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.
摘要翻译： CT系统包括台架，X射线源，检测器和包括交替的第一和第二材料的光栅准直器。该系统包括控制器，该控制器被配置为从第一焦点和第一检测器像素发射第一X射线束，其中第一射线束沿着光线并通过光栅准直器的第一材料之一并且随后从第二焦点和第一检测器像素发射第二射线束，其中所述第二光束X射线基本上沿着所述光线并通过所述光栅准直器的所述第二材料之一通过。该系统包括被编程为使用从第一光束和第二光束获得的数据来生成第一和第二kVp图像数据集的计算机，并重构对象的基础材料图像。

15. 发明申请

US20120008842A1 SYSTEM AND METHOD OF IMAGE ARTIFACT REDUCTION USING SELF-NAVIGATED REAL-TIME PHASE CORRECTION IN ECHO PLANAR IMAGING 有权
标题翻译：使用自主导航的实时相位校正在ECHO平面图像中的图像艺术减少的系统和方法
公开(公告)号：US20120008842A1
公开(公告)日：2012-01-12
申请号：US12831562
申请日：2010-07-07
申请人： Richard Scott Hinks , Dan Xu
发明人： Richard Scott Hinks , Dan Xu
IPC分类号： G06K9/00 , G01R33/48
CPC分类号： G01R33/56554 , A61B5/055 , A61B5/7285 , G01R33/56563
摘要： An apparatus and method include a computer programmed to implement a scan sequence configured to elicit scan data, wherein the scan sequence comprises an echo planar imaging (EPI) sequence configured to elicit the image data and to acquire the scan data. The computer is also programmed to manipulate the scan data to determine a first plurality of phase errors in the image data responsible for a Nyquist ghost, wherein the manipulated scan data is free of navigator echo data, remove the first plurality of phase errors from the image data, and reconstruct an image based on the image data having the first plurality of phase errors removed therefrom.
摘要翻译：一种装置和方法包括被编程为实现被配置为引出扫描数据的扫描序列的计算机，其中扫描序列包括被配置为引出图像数据并获取扫描数据的回波平面成像（EPI）序列。计算机还被编程为操纵扫描数据以确定负责奈奎斯特幽灵的图像数据中的第一多个相位误差，其中所述被操纵的扫描数据没有导航回波数据，从图像中去除第一多个相位误差数据，并且基于从其中移除了第一多个相位误差的图像数据重建图像。

16. 发明申请

US20090082243A1 DETERGENT PARTICLE 审中-公开
标题翻译：洗涤颗粒
公开(公告)号：US20090082243A1
公开(公告)日：2009-03-26
申请号：US12211982
申请日：2008-09-17
申请人： Anju Deepali Massey Brooker , Alberto Martinez-Becares , David William York , Dan Xu , Gillian Margaret Hardy
发明人： Anju Deepali Massey Brooker , Alberto Martinez-Becares , David William York , Dan Xu , Gillian Margaret Hardy
IPC分类号： C11D7/02 , B32B1/00
CPC分类号： C11D3/126 , C11D17/06 , Y10T428/2982
摘要： A particle having a size of from about 50 to about 1,000 μm comprising a low-shear exfoliable nanoclay, the nanoclay having a primary particle size of from about 10 to about 300 nm. The invention also includes detergents comprising the particle and a process for making the particle.
摘要翻译：尺寸为约50至约1,000μm的颗粒包含低剪切可剥离的纳米粘土，所述纳米粘土具有约10至约300nm的初级粒度。本发明还包括包含颗粒的洗涤剂和制备颗粒的方法。

17. 发明申请

US20090082242A1 DISHWASHING METHOD 审中-公开
标题翻译：洗衣方法
公开(公告)号：US20090082242A1
公开(公告)日：2009-03-26
申请号：US12211968
申请日：2008-09-17
申请人： Anju Deepali Massey Brooker , Alberto Martinez-Becares , David William York , Dan Xu
发明人： Anju Deepali Massey Brooker , Alberto Martinez-Becares , David William York , Dan Xu
IPC分类号： C11D3/02
CPC分类号： C11D3/1253
摘要： A method of cleaning a soiled load in an automatic dishwasher comprising the step of contacting the load with a phosphate free wash liquor comprising exfoliated nanoclay, the liquor having a pH of from about 9 to about 12 and an ionic strength of from about 0.001 to about 0.02 moles/l.
摘要翻译：一种在自动洗碗机中清洁污染负载的方法，包括使负载与含有剥离的纳米粘土的无磷酸盐洗涤液接触的步骤，所述液体的pH为约9至约12，离子强度为约0.001至约 0.02摩尔/升。

18. 发明授权

US07466131B1 System and method for designing multi-channel RF pulses for MR imaging 有权
标题翻译：用于MR成像设计多通道RF脉冲的系统和方法
公开(公告)号：US07466131B1
公开(公告)日：2008-12-16
申请号：US11738225
申请日：2007-04-20
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01V3/00
CPC分类号： G01R33/4836 , G01R33/4824 , G01R33/4833
摘要： A system and method are provided for designing RF pulses for multi-channel and/or multi-dimensional spatially-selective applications using a linear approximation. Embodiments of the system and method may use a generalized linear-class large tip angle approximation to design RF pulses for multi-channel and parallel transmission. Further, some of these approximations allow for the design of arbitrarily large flip angles, irregularly-shaped flip angle profiles, or arbitrary initial magnetization values. Embodiments of the system and method may also provide for the design of k-space trajectories which aid in maintaining assumptions of the various linear class approximations.
摘要翻译：提供了一种系统和方法，用于使用线性近似来设计用于多通道和/或多维空间选择性应用的RF脉冲。该系统和方法的实施例可以使用广义线性级大尖角近似来设计用于多通道和并行传输的RF脉冲。此外，这些近似中的一些允许设计任意大的翻转角，不规则形状的翻转轮廓或任意的初始磁化值。系统和方法的实施例还可以提供有助于维持各种线性类近似的假设的k空间轨迹的设计。

19. 发明申请

US20080238425A1 SYSTEM AND METHOD FOR DESIGNING IMPROVED RF PULSE PROFILES 有权
标题翻译：用于设计改进的RF脉冲轮廓的系统和方法
公开(公告)号：US20080238425A1
公开(公告)日：2008-10-02
申请号：US11694617
申请日：2007-03-30
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01R33/32
CPC分类号： G01R33/4833
摘要： A system and method are provided for designing RF pulses which have improved magnetization profiles. By utilizing an optimal control approach as an alternative to, or in combination with, non-iterative approximations, RF pulses generated by the system and method described herein will exhibit less deviation from that of “ideal” Bloch solutions. Consequently, the magnetization profiles produced by the RF pulses generated by the system and method described herein will be closer to the desired profiles. In addition, limitations of non-iterative approximations, such as maximum tip angle limits and linearity constraints, can be avoided.
摘要翻译：提供了一种用于设计具有改进的磁化分布的RF脉冲的系统和方法。通过利用最优控制方法作为非迭代近似的替代方案或与非迭代近似组合，由本文描述的系统和方法产生的RF脉冲将表现出与“理想”Bloch解决方案的偏差较小的偏差。因此，由本文所述的系统和方法产生的RF脉冲产生的磁化曲线将更接近所需的轮廓。此外，可以避免非迭代近似的限制，例如最大尖角限制和线性约束。

20. 发明授权

US08483457B2 System and method of image artifact reduction using self-navigated real-time phase correction in echo planar imaging 有权
标题翻译：在回波平面成像中使用自导航实时相位校正的图像伪像减少的系统和方法
公开(公告)号：US08483457B2
公开(公告)日：2013-07-09
申请号：US12831562
申请日：2010-07-07
申请人： Richard Scott Hinks , Dan Xu
发明人： Richard Scott Hinks , Dan Xu
IPC分类号： G06K9/00
CPC分类号： G01R33/56554 , A61B5/055 , A61B5/7285 , G01R33/56563
摘要： An apparatus and method include a computer programmed to implement a scan sequence configured to elicit scan data, wherein the scan sequence comprises an echo planar imaging (EPI) sequence configured to elicit the image data and to acquire the scan data. The computer is also programmed to manipulate the scan data to determine a first plurality of phase errors in the image data responsible for a Nyquist ghost, wherein the manipulated scan data is free of navigator echo data, remove the first plurality of phase errors from the image data, and reconstruct an image based on the image data having the first plurality of phase errors removed therefrom.
摘要翻译：一种装置和方法包括被编程为实现被配置为引出扫描数据的扫描序列的计算机，其中扫描序列包括被配置为引出图像数据并获取扫描数据的回波平面成像（EPI）序列。计算机还被编程为操纵扫描数据以确定负责奈奎斯特幽灵的图像数据中的第一多个相位误差，其中所述被操纵的扫描数据没有导航回波数据，从图像中去除第一多个相位误差数据，并且基于从其中移除了第一多个相位误差的图像数据重建图像。

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