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11. 发明授权

US11285294B2 Introducer with sheath having a withdrawal support wire 有权
公开(公告)号：US11285294B2
公开(公告)日：2022-03-29
申请号：US16454459
申请日：2019-06-27
申请人： Cook Medical Technologies LLC
发明人： Patrick G. McElhaney , Thomas A. Osborne
IPC分类号： A61M25/06 , A61M25/00 , A61M29/00 , G05B19/4155 , A61M25/01 , A01G25/16
摘要： An introducer includes a dilator received in a lumen defined by an introducer sheath and including a dilation end extending distally beyond a distal end of the introducer sheath. The introducer sheath includes a flat wire reinforcement having a hollow cylindrical shape sandwiched between an inner PTFE tube and an outer nylon tube. The outer nylon tube includes a distal segment that extends distally beyond the PTFE tube, which extends distally beyond the PTFE tube, which extends distally beyond the flat wire reinforcement. A withdrawal support wire has a distal end attached to a distal end turn of the flat wire reinforcement and extends in a proximal direction in parallel with a longitudinal axis between an outer surface of the nylon tube and an inner surface of the PTFE tube. The withdrawal support wire is configured to be in tension when the sheath is placed in tension to inhibit distal stretch separation breakage.

12. 发明授权

US09555215B2 Treatment fluid delivery method, and turbulator for promoting uptake of a treatment agent 有权
标题翻译：处理液输送方法和用于促进处理剂吸收的湍流器
公开(公告)号：US09555215B2
公开(公告)日：2017-01-31
申请号：US14938906
申请日：2015-11-12
申请人： Cook Medical Technologies LLC
发明人： James R. Randolph , Thomas A. Osborne
IPC分类号： A61M25/00 , A61M25/01 , A61B17/22
CPC分类号： A61M25/0023 , A61B17/22 , A61M25/0021 , A61M25/0043 , A61M25/0067 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0102 , A61M2025/0057 , A61M2025/0063 , A61M2025/0073
摘要： A turbulator for promoting mixing of fluids passing through a body lumen includes an elongate flow perturbing component and an elongate shape controlling component freely slidable within the flow perturbing component. The turbulator is adjustable from a low profile, lumen access configuration to a deployed configuration via sliding the shape controlling component within the flow perturbing component. Adjusting the turbulator within a body lumen of a patient induces turbulence within a flow of fluid passing through the body lumen to increase mixing of a treatment fluid with the body fluid by way of the induced turbulence.
摘要翻译：用于促进通过体腔的流体的混合的湍流器包括细长的流动扰动部件和在流动扰动部件内可自由滑动的细长形状控制部件。通过在流动扰动部件内滑动形状控制部件，可以将紊流器从低轮廓，内腔存取配置调整到展开配置。调节患者体腔内的湍流器在通过体腔的流体流中引起湍流，以通过诱导的湍流增加治疗流体与体液的混合。

13. 发明申请

US20160262737A1 DEVICES AND METHODS USEFUL FOR SEALING BODILY OPENINGS 审中-公开
标题翻译：用于密封裸露开口的装置和方法
公开(公告)号：US20160262737A1
公开(公告)日：2016-09-15
申请号：US15062749
申请日：2016-03-07
申请人： Cook Medical Technologies LLC , Cook Biotech Incorporated
发明人： Ram H. Paul, JR. , Cleon Stanley , Brian L. Bates , F. Joseph Obermiller , Thomas A. Osborne , Sean D. Chambers
IPC分类号： A61B17/00
摘要： Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.
摘要翻译：除此之外，还公开了用于医疗密封容器或壁中的开口的装置和方法。例如，在医疗应用中，提供输送管用于通过护套插入血管（例如血管）中。固定在细丝上的圆顶形密封件，吸收性和/或可压缩缓冲器以及锁定构件设置在输送管中。输送管被构造成使得其可以通过护套插入到容器中。在灯丝上保持张力以将密封件保持在管或鞘上。护套被拉出，同时拉出管子，将密封件留在血管壁的开口处。锁定构件将缓冲器压靠在容器的外部，并且灯丝将密封件保持在与容器内部的适当位置。

14. 发明申请

US20150367098A1 CATHETER OR SHEATH ASSEMBLY 审中-公开
标题翻译：导管或护套组件
公开(公告)号：US20150367098A1
公开(公告)日：2015-12-24
申请号：US14725093
申请日：2015-05-29
申请人： Cook Medical Technologies, LLC
发明人： Steen Aggerholm , David Drewes , Thomas A. Osborne , Brett Baker
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0012 , A61M25/0045 , A61M2025/0059
摘要： A catheter or sheath includes an inner layer made of a relatively hard material, an intermediate layer formed of a strengthening member and being provided with interstitial material in the spaces between the elements of the strengthening member. Overlying the intermediate layer is an outer layer of, for example, polyamide. The interstitial material is relatively soft, which allows the catheter to be bent to smaller radii of curvature than prior art catheters with reduced risk of kinking.
摘要翻译：导管或护套包括由相对硬的材料制成的内层，由加强构件形成的中间层，并且在加强构件的元件之间的空间中设置间隙材料。覆盖中间层是例如聚酰胺的外层。间隙材料相对较软，其允许导管弯曲成比现有技术导管更小的曲率半径，具有降低的扭结风险。

15. 发明申请

US20200054860A1 INTRODUCER WITH SHEATH HAVING A WITHDRAWAL SUPPORT WIRE 审中-公开
公开(公告)号：US20200054860A1
公开(公告)日：2020-02-20
申请号：US16454459
申请日：2019-06-27
申请人： Cook Medical Technologies LLC
发明人： Patrick G. McElhaney , Thomas A. Osborne
IPC分类号： A61M25/06 , A61M29/00 , A61M25/00
摘要： An introducer includes a dilator received in a lumen defined by an introducer sheath and including a dilation end extending distally beyond a distal end of the introducer sheath. The introducer sheath includes a flat wire reinforcement having a hollow cylindrical shape sandwiched between an inner PTFE tube and an outer nylon tube. The outer nylon tube includes a distal segment that extends distally beyond the PTFE tube, which extends distally beyond the PTFE tube, which extends distally beyond the flat wire reinforcement. A withdrawal support wire has a distal end attached to a distal end turn of the flat wire reinforcement and extends in a proximal direction in parallel with a longitudinal axis between an outer surface of the nylon tube and an inner surface of the PTFE tube. The withdrawal support wire is configured to be in tension when the sheath is placed in tension to inhibit distal stretch separation breakage.

16. 发明授权

US10441256B2 Devices and methods useful for sealing bodily openings 有权
公开(公告)号：US10441256B2
公开(公告)日：2019-10-15
申请号：US15062749
申请日：2016-03-07
申请人： Cook Medical Technologies LLC , Cook Biotech Incorporated
发明人： Ram H. Paul, Jr. , Cleon Stanley , Brian L. Bates , F. Joseph Obermiller , Thomas A. Osborne , Sean D. Chambers
IPC分类号： A61B17/00 , A61B17/04 , A61B17/34 , A61B17/06
摘要： Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.

17. 发明授权

US10213209B2 Occluding device and method of occluding fluid flow through a body vessel 有权
公开(公告)号：US10213209B2
公开(公告)日：2019-02-26
申请号：US15054682
申请日：2016-02-26
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： Robert I. White, Jr. , Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B17/12
摘要： An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.

18. 发明授权

US09414892B2 Device for controlling marker wire 有权
标题翻译：用于控制标记线的装置
公开(公告)号：US09414892B2
公开(公告)日：2016-08-16
申请号：US13802979
申请日：2013-03-14
申请人： Cook Medical Technologies LLC
发明人： Grant S. Ritter , Thomas W. McGhie , Thomas A. Osborne
IPC分类号： A61B19/00 , A61B17/00
CPC分类号： A61B90/39 , A61B2017/00951 , A61B2090/3908 , A61B2090/3987 , A61B2090/3991
摘要： Arrangements are disclosed in which proximal portions of a marker wire are effectively secured. In one embodiment, a proximal portion of the marker wire is positioned inside a tubular member that allows for slidable movement of the marker wire within the tubular member. In some embodiments, a proximal portion of the marker wire is coupled to a spring member. Some embodiments also disclose a movement-resisting member having flaps that contact the surface of the marker wire and resist movement of the marker wire in one or more directions.
摘要翻译：公开了一种标记线的近端部分被有效地固定的布置。在一个实施例中，标记线的近端部分位于允许标记线在管状构件内滑动移动的管状构件内。在一些实施例中，标记线的近端部分联接到弹簧构件。一些实施例还公开了具有与标记线的表面接触并且阻止标记线在一个或多个方向上移动的折片的运动抵抗构件。

19. 发明申请

US20160174990A1 OCCLUDING DEVICE AND METHOD OF OCCLUDING FLUID FLOW THROUGH A BODY VESSEL 审中-公开
标题翻译：通过身体血管堵塞流体的装置和方法
公开(公告)号：US20160174990A1
公开(公告)日：2016-06-23
申请号：US15054682
申请日：2016-02-26
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： Robert I. White, JR. , Thomas A. Osborne , Kurt J. Tekulve
IPC分类号： A61B17/12
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B2017/1205
摘要： An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.
摘要翻译：用于阻塞流体流过身体血管的内腔的闭塞装置。该装置包括线圈和附接到线圈的纤维。线圈具有约5至60克的初始张力，以方便线圈在展开时折叠。纤维从线圈延伸一段长度。

20. 发明授权

US09308347B2 Treatment fluid delivery method, and turbulator for promoting uptake of a treatment agent 有权
标题翻译：处理液输送方法和用于促进处理剂吸收的湍流器
公开(公告)号：US09308347B2
公开(公告)日：2016-04-12
申请号：US14187748
申请日：2014-02-24
申请人： Cook Medical Technologies LLC
发明人： James R. Randolph , Thomas A. Osborne
IPC分类号： A61M25/00 , A61M25/01 , A61B17/22
CPC分类号： A61M25/0023 , A61B17/22 , A61M25/0021 , A61M25/0043 , A61M25/0067 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0102 , A61M2025/0057 , A61M2025/0063 , A61M2025/0073
摘要： A turbulator for promoting mixing of fluids passing through a body lumen includes an elongate flow perturbing component and an elongate shape controlling component freely slidable within the flow perturbing component. The turbulator is adjustable from a low profile, lumen access configuration to a deployed configuration via sliding the shape controlling component within the flow perturbing component. Adjusting the turbulator within a body lumen of a patient induces turbulence within a flow of fluid passing through the body lumen to increase mixing of a treatment fluid with the body fluid by way of the induced turbulence.
摘要翻译：用于促进通过体腔的流体的混合的湍流器包括细长的流动扰动部件和在流动扰动部件内可自由滑动的细长形状控制部件。通过在流动扰动部件内滑动形状控制部件，可以将紊流器从低轮廓，内腔存取配置调整到展开配置。调节患者体腔内的湍流器在通过体腔的流体流中引起湍流，以通过诱导的湍流增加治疗流体与体液的混合。

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