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11. 发明授权

US08058620B2 Method for improving clinical data quality in positron emission tomography 失效
标题翻译：正电子发射断层扫描技术提高临床资料质量的方法
公开(公告)号：US08058620B2
公开(公告)日：2011-11-15
申请号：US12917701
申请日：2010-11-02
申请人： Bernard Bendriem , Michael E. Casey , Charles C. Watson
发明人： Bernard Bendriem , Michael E. Casey , Charles C. Watson
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , G01T7/005
摘要： A method for improving clinical data quality in Positron Emission Tomography (PET). The method provides for the processing of PET data to accurately and efficiently determine a data signal-to-noise (SNR) corresponding to each individual clinical patient scan, as a function of a singles rate in a PET scanner. The method relates an injected dose to the singles rate to determine SNR(Dinj), and provides an accurate estimate of quantity proportional to SNR, similar in function to SNR(Dinj). Knowledge of SNR(Dinj) permits determination of peak SNR, optimal dose, SNR deficit, dose deficit, and differential dose benefit. The patient dose is fractionated, with a small calibration dose given initially. After a short uptake, the patient is pre-scanned to determine T, S, and R. An optimal dose is then determined and the remainder is injected.
摘要翻译：一种改善正电子发射断层扫描（PET）临床数据质量的方法。该方法提供PET数据的处理，以便根据PET扫描仪中的单打率来准确有效地确定与每个单独的临床患者扫描相对应的数据信噪比（SNR）。该方法将注射剂量与单打率相关联以确定SNR（Dinj），并提供与SNR成比例的量的准确估计，其功能类似于SNR（Dinj）。 SNR（Dinj）的知识允许确定峰值SNR，最佳剂量，SNR赤字，剂量缺陷和差异剂量效益。对患者剂量进行分级，最初给予较小的校准剂量。经过短暂摄取后，患者被预先扫描以确定T，S和R.然后确定最佳剂量，并注射剩余部分。

12. 发明申请

US20090072155A1 TIME-OF-FLIGHT (TOF) POSITRON EMISSION TOMOGRAPHY (PET) RECONSTRUCTION FROM TIME-TRUNCATED PROJECTION DATA 有权
标题翻译：从时间截断投影数据中的飞行时间（TOF）POSITRON排放测量（PET）重建
公开(公告)号：US20090072155A1
公开(公告)日：2009-03-19
申请号：US12212130
申请日：2008-09-17
申请人： Charles C. Watson , Vladimir Panin , Bernard Bendriem , Michael E. Casey
发明人： Charles C. Watson , Vladimir Panin , Bernard Bendriem , Michael E. Casey
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037
摘要： A method of TOF-PET image reconstruction using time-truncated TOF-PET projection data. The time-truncated TOF-PET data is obtained by narrowing the scanner time window to a smaller “time window field of view,” which reduces the field of view of a TOF-PET scanner. This results in a lower list mode stream transfer rate, which can be useful in high count rate data acquisitions, in particular 82Rb cardiac studies.
摘要翻译：使用时间截断的TOF-PET投影数据的TOF-PET图像重建方法。通过将扫描仪时间窗缩小到更小的“时间窗视野”来获得时间截断的TOF-PET数据，这减少了TOF-PET扫描仪的视场。这导致较低的列表模式流传输速率，其可用于高计数率数据采集，特别是82Rb心脏研究。

13. 发明授权

US09217795B2 Integrated digital discriminator for a silicon photomultiplier 有权
标题翻译：用于硅光电倍增管的集成数字鉴别器
公开(公告)号：US09217795B2
公开(公告)日：2015-12-22
申请号：US13556331
申请日：2012-07-24
申请人： Peter Hansen , Michael E. Casey , Stefan B. Siegel
发明人： Peter Hansen , Michael E. Casey , Stefan B. Siegel
IPC分类号： G01F15/06 , G01T1/24
CPC分类号： G01J1/44 , G01T1/248 , G01T1/2985 , H03K3/037 , H03K5/135 , H03K2005/00078
摘要： Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.
摘要翻译：提供了使暗电流脉冲的影响最小化的装置和方法。例如，在本发明的一个实施例中，提供了一种方法，其中第一像素被撞击（即，主像素）。在主要像素被击打之后的固定时间帧内撞击的像素被称为次要像素。在短的固定时间段到期后，添加主要和次要像素的数量。如果计数超过阈值，则主像素由来自真实伽马事件的第一（或早）光子激活。如果阈值不满足，则主要像素可能产生应忽略的暗脉冲。

14. 发明授权

US08913810B2 Simultaneous reconstruction of emission activity and attenuation coefficient distribution from TOF data, acquired with external shell source 有权
标题翻译：从TOF数据同时重建排放活动和衰减系数分布，采用外壳来源采集
公开(公告)号：US08913810B2
公开(公告)日：2014-12-16
申请号：US13555308
申请日：2012-07-23
申请人： Vladimir Y. Panin , Michael E. Casey
发明人： Vladimir Y. Panin , Michael E. Casey
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/424
摘要： Methods, and systems therefrom, for generating images from time of flight (TOF) data associated with a scan of at least one object using a positron emission tomography system are provided. The method includes providing initial values for an activity image to yield a current activity image. The method also includes estimating initial values for an attenuation map (μ-map) image based on the TOF data to yield a current μ-map image. The method further includes repeating, until at least one termination condition is met, the steps of updating the current activity image based on at least the current μ-map and a first update algorithm and updating the current μ-map image based on at least on the updated activity image and a second update algorithm. The method also includes outputting an image of the at least one object based on the current μ-map and the current activity image.
摘要翻译：提供了用于使用正电子发射断层摄影系统从与至少一个物体的扫描有关的飞行时间（TOF）数据生成图像的方法和系统。该方法包括提供活动图像的初始值以产生当前活动图像。该方法还包括基于TOF数据估计衰减映射（μ映射）图像的初始值以产生当前的μ映射图像。该方法还包括重复直到至少一个终止条件被满足为基于至少基于当前μ映射和第一更新算法来更新当前活动图像的步骤，并且至少基于上述步骤更新当前的μ映射图像更新的活动图像和第二更新算法。该方法还包括基于当前μ图和当前活动图像输出至少一个对象的图像。

15. 发明授权

US08352811B2 Method and apparatus for reducing positron emission tomography (PET) event losses by effective bandwidth utilization 有权
标题翻译：通过有效带宽利用减少正电子发射断层扫描（PET）事件损失的方法和装置
公开(公告)号：US08352811B2
公开(公告)日：2013-01-08
申请号：US12560048
申请日：2009-09-15
申请人： Michael E. Casey , Andrew P. Moor , Kenneth Puterbaugh
发明人： Michael E. Casey , Andrew P. Moor , Kenneth Puterbaugh
IPC分类号： G06F11/07 , G06F11/25
CPC分类号： G01T1/00
摘要： An event data transmission scheme is provided for reducing positron emission tomography event losses. The event data transmission scheme employs a more effective use of available data bandwidth. Each of a plurality of detector data slots is connected directly to a data aggregation control interface, and the control interface is connected to a coincidence processor.
摘要翻译：提供一种用于减少正电子发射断层摄影事件损失的事件数据传输方案。事件数据传输方案更有效地利用可用的数据带宽。多个检测器数据时隙中的每一个直接连接到数据聚合控制接口，并且控制接口连接到重合处理器。

16. 发明申请

US20100070808A1 METHOD AND APPARATUS FOR REDUCING POSITRON EMISSION TOMOGRAPHY (PET) EVENT LOSSES BY EFFECTIVE BANDWIDTH UTILIZATION 有权
标题翻译：通过有效的带宽利用减少POSITRON排放TOMOGRAPHY（PET）事件损失的方法和装置
公开(公告)号：US20100070808A1
公开(公告)日：2010-03-18
申请号：US12560048
申请日：2009-09-15
申请人： Michael E. Casey , Andrew P. Moor , Kenneth PUTERBAUGH
发明人： Michael E. Casey , Andrew P. Moor , Kenneth PUTERBAUGH
IPC分类号： G06F11/00
CPC分类号： G01T1/00
摘要： An event data transmission scheme is provided for reducing positron emission tomography event losses. The event data transmission scheme employs a more effective use of available data bandwidth. Each of a plurality of detector data slots is connected directly to a data aggregation control interface, and the control interface is connected to a coincidence processor.
摘要翻译：提供一种用于减少正电子发射断层摄影事件损失的事件数据传输方案。事件数据传输方案更有效地利用可用的数据带宽。多个检测器数据时隙中的每一个直接连接到数据聚合控制接口，并且控制接口连接到重合处理器。

17. 发明申请

US20090076379A1 Ultrasonic Imager for Motion Measurement in Multi-Modality Emission Imaging 有权
标题翻译：超声波成像仪用于多模式发射成像中的运动测量
公开(公告)号：US20090076379A1
公开(公告)日：2009-03-19
申请号：US12125329
申请日：2008-05-22
申请人： James J. Hamill , Gunther Platsch , Michael E. Casey
发明人： James J. Hamill , Gunther Platsch , Michael E. Casey
IPC分类号： A61B8/14 , A61B5/05
CPC分类号： A61B8/08 , A61B5/7285 , A61B6/032 , A61B6/5247 , A61B6/541 , A61B8/4245 , A61B8/5238 , A61B8/543 , G01T1/1603
摘要： A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.
摘要翻译：一种医疗成像装置具有发射断层摄影机，至少一个超声波（US）探头，用于提供给出关于被检体的内部器官的位置的实时信息的图像，用于相对于空间定位至少一个超声波探头的跟踪系统以及图像处理单元，其中由超声波探头获得的位置信息用于由发射断层摄影机获得的图像信息的衰减校正。

18. 发明申请

US20090072131A1 Estimation of Crystal Efficiency With Axially Compressed Sinogram 有权
公开(公告)号：US20090072131A1
公开(公告)日：2009-03-19
申请号：US12212457
申请日：2008-09-17
申请人： Mu Chen , Vladimir Panin , Michael E. Casey
发明人： Mu Chen , Vladimir Panin , Michael E. Casey
IPC分类号： G01D18/00
CPC分类号： G01T1/2985 , A61B6/037 , G01T7/005
摘要： The present invention provides a method for estimating crystal efficiency in a PET detector that takes axial compression into account. It does so via an iterative methodology in which a μ-map is first generated and then is used to obtain a solution for the equation L  ( ɛ i ) = ∑ n ∈ N   y n  log  ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij - ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij , wherein gij is a geometric factor for LOR(i,j), εi and εj are the efficiencies for crystal i and crystal j, and xij is the line integral of the source distribution along LOR(i,j). Once efficiencies are determined, they are used to calibrate the PET detector.

19. 发明授权

US07465927B2 Attenuation correction for nuclear medical imaging scanners with simultaneous transmission and emission acquisition 失效
标题翻译：具有同时传输和发射采集的核医学成像扫描仪的衰减校正
公开(公告)号：US07465927B2
公开(公告)日：2008-12-16
申请号：US11387263
申请日：2006-03-23
申请人： Vladimir Panin , Maurizio Conti , Michael E. Casey
发明人： Vladimir Panin , Maurizio Conti , Michael E. Casey
IPC分类号： G01T1/164
CPC分类号： G01T1/1617
摘要： For patient transmission data acquired simultaneously with patient emission data, blank transmission data are acquired in the absence of the patient emission and therefore under count rate conditions different from the count rate conditions of the patient transmission data. To prevent the different count rate conditions from causing artifacts in reconstructed tomographic images, a correction is made for spatially varying count rate effects on the attenuation correction. For example, the blank scan data are adjusted according to the count rate at which the patient emission data are acquired, and the adjusted blank scan data and the patient transmission data are used for attenuation correction of the patient emission data used for reconstructing a tomographic image.
摘要翻译：对于与患者发射数据同时获得的患者传输数据，在不存在患者发射的情况下获取空白传输数据，因此在与患者传输数据的计数速率条件不同的计数速率条件下获取。为了防止不同的计数率条件在重建的断层图像中造成伪像，对空间变化的计数率对衰减校正的影响进行了校正。例如，根据获取患者发射数据的计数率来调整空白扫描数据，并且将经调整的空白扫描数据和患者传输数据用于用于重建断层图像的患者排放数据的衰减校正。

20. 发明授权

US06565489B2 Angled-adjustable rowing exerciser 失效
公开(公告)号：US06565489B2
公开(公告)日：2003-05-20
申请号：US09956378
申请日：2001-09-18
申请人： Sung-Cho Ho , Michael E. Casey
发明人： Sung-Cho Ho , Michael E. Casey
IPC分类号： A63B21068
CPC分类号： A63B23/0211 , A63B21/068 , A63B22/0076 , A63B22/0089 , A63B23/0222 , A63B2022/0084 , A63B2208/02
摘要： An angle-adjustable rowing exerciser, which includes a wheeled base frame, a fixed mattress and a pivoted mattress supported on the base frame, a transverse frame bar pivotally mounted on the base frame at the bottom, two handlebars respectively adjustably connected to two adjustable ratchet connectors at the ends of the transverse frame bar for turning by hand to rotate the transverse frame bar, and two actuating bars perpendicularly and fixedly connected to the transverse frame bar and forced to tilt the base frame or the movable mattress up and down upon turning of the handlebars.

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