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11. 发明申请

US20050045914A1 Flip chip device assembly machine 审中-公开
标题翻译：倒装芯片装配机
公开(公告)号：US20050045914A1
公开(公告)日：2005-03-03
申请号：US10888520
申请日：2004-07-08
申请人： Edward Agranat , Matthew Bouche , Dennis Carew , Nicholas Celia , Michael Chalsen , Cyriac Devasia , Brian Evans , David Greco , Gheorghe Pascariu , Russell Wheeler
发明人： Edward Agranat , Matthew Bouche , Dennis Carew , Nicholas Celia , Michael Chalsen , Cyriac Devasia , Brian Evans , David Greco , Gheorghe Pascariu , Russell Wheeler
IPC分类号： H01L20060101 , H01L21/00 , H01L29/739
CPC分类号： H01L21/67144 , H01L21/67132 , H01L2224/11822 , H01L2224/81011 , H01L2924/00013 , H05K3/3436 , H05K3/3489 , H01L2224/29099
摘要： A flip chip assembly machine (FCAM) (30) includes a main gantry (50) and a substrate camera gantry (40) that are configured to operate independently of each other and, respectively, support a die (12) and a substrate camera (38) for alignment purposes. The FCAM further includes a fluxer (130) for applying flux to the die. A flip-to-flux pick and place subassembly (116) picks up a die and places it in flux (46) independently of the operation of the main gantry, which may perform another task during the flux dwell time. A substrate carrier conveyor (154) includes a walking beam (260) to rapidly accelerate and decelerate substrate carrier movement into and out of the FCAM.
摘要翻译：倒装芯片组装机（FCAM）（30）包括主机架（50）和基板相机机架（40），其被配置为彼此独立地操作，并且分别支撑模具（12）和基板相机 38）用于对齐目的。 FCAM还包括用于向模具施加通量的助熔剂（130）。反向通量拾取和放置子组件（116）拾取模具并将其放置在通量（46）中，独立于主机架的操作，其可以在通量驻留时间期间执行另一任务。衬底载体传送器（154）包括步进梁（260），用于快速加速和减速衬底载体运动进入和离开FCAM。

12. 发明授权

US5843966A Piperidine derivatives 失效
标题翻译：哌啶衍生物
公开(公告)号：US5843966A
公开(公告)日：1998-12-01
申请号：US899190
申请日：1997-07-23
申请人： Duncan Robert Armour , Brian Evans , David Middlemiss , Tania Hubbard , Michael Menteith Hann , Xiao-Qing Lewell , Stephen Paul Watson , Alan Naylor , Neil Anthony Pegg , Maria Victoria Vinader , Gerard Martin Paul Giblin
发明人： Duncan Robert Armour , Brian Evans , David Middlemiss , Tania Hubbard , Michael Menteith Hann , Xiao-Qing Lewell , Stephen Paul Watson , Alan Naylor , Neil Anthony Pegg , Maria Victoria Vinader , Gerard Martin Paul Giblin
IPC分类号： A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4523 , A61K31/454 , A61P1/00 , A61P1/08 , A61P25/04 , A61P29/00 , A61P43/00 , C07D20060101 , C07D211/56 , C07D401/10 , C07D401/12
CPC分类号： C07D401/12
摘要： The present invention relates to piperidine derivatives of formula (I) ##STR1## wherein R.sup.1 is a C.sub.1-4 alkoxy group; R.sup.2 is ##STR2## R.sup.3 is a hydrogen or halogen atom; R.sup.4 and R.sup.5 may each independently represent a hydrogen or halogen atom, or a C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl group; R.sup.6 is a hydrogen atom, a C.sub.1-4 alkyl, (CH.sub.2).sub.m cyclopropyl, --S(O).sub.n C.sub.1-4 alkyl, phenyl, NR.sup.7 R.sub.8, CH.sub.2 C(O)CF.sub.3 or trifluoromethyl group; R.sup.7 and R.sup.8 may each independently represent a hydrogen atom, or a C.sub.1-4 alkyl or acyl group; x represents zero or 1; n represents zero, 1 or 2; m represents zero or 1; and pharmaceutically acceptable salts and solvates thereof; to processes for their preparation; and their use in the treatment of conditions mediated by tachykinins.
摘要翻译：本发明涉及式（I）的哌啶衍生物其中R 1为C 1-4烷氧基; R 2是氢或卤素原子; R 4和R 5可各自独立地表示氢或卤素原子，或C 1-4烷基，C 1-4烷氧基或三氟甲基; R6是氢原子，C1-4烷基，（CH2）环丙基，-S（O）nC1-4烷基，苯基，NR7R8，CH2C（O）CF3或三氟甲基; R 7和R 8可各自独立地表示氢原子或C 1-4烷基或酰基; x表示零或1; n表示0，1或2; m表示0或1; 及其药学上可接受的盐和溶剂合物; 进行准备; 及其用于治疗由速激肽介导的病症。

13. 发明授权

US4833153A Indole derivatives 失效
标题翻译：吲哚衍生物
公开(公告)号：US4833153A
公开(公告)日：1989-05-23
申请号：US928037
申请日：1986-11-07
申请人： Michael D. Dowle , Brian Evans , Peter Clark
发明人： Michael D. Dowle , Brian Evans , Peter Clark
IPC分类号： C07D209/16 , C07D403/06
CPC分类号： C07D403/06 , C07D209/16
摘要： Compounds are disclosed of formula (I): ##STR1## wherein one of R.sup.1, R.sup.2 and R.sup.3 represents hydrogen, C.sub.1-6 alkyl C.sub.3-6 alkenyl, hydroxy, C.sub.1-4 alkoxy or a C.sub.2-5 alkoxycarbonyl group, a phenyl or substituted phenyl group or a phen(C.sub.1-4)alkyl or substituted phen(C.sub.1-4)alkyl group; and the other two each independently represents hydrogen, C.sub.1-6 alkyl, or R.sup.2 and R.sup.3 together form an alkylene chain --(CH.sub.2).sub.n --where n is 2 or 3, bridging the nitrogen atoms to which they are attached; R.sup.4 and R.sup.5, each independently represents hydrogen, C.sub.1-3 alkyl or propenyl; R.sup.6 represents hydrogen, C.sub.1-3 alkyl, and the physiologically acceptable salts and solvates thereof.The compounds (I) have potent and selective vasoconstrictor activity and are potentially useful for the treatment of migraine. The compounds (I) may be formulated in conventional manner as pharmaceutical compositions for administration by any convenient route.
摘要翻译：公开了式（I）的化合物：其中R 1，R 2和R 3中的一个表示氢，C 1-6烷基C 3-6烯基，羟基，C 1-4烷氧基或C 2-5烷氧基羰基，苯基或取代的苯基或苯基（C 1-4）烷基或取代的苯基（C 1-4）烷基; 而另外两个独立地表示氢，C 1-6烷基或R 2和R 3一起形成亚烷基链 - （CH 2）n - ，其中n为2或3，桥接与它们相连的氮原子; R 4和R 5各自独立地表示氢，C 1-3烷基或丙烯基; R6代表氢，C1-3烷基及其生理上可接受的盐和溶剂合物。化合物（I）具有有效和选择性的血管收缩剂活性，并且可用于治疗偏头痛。化合物（I）可以以常规方式配制为用于通过任何方便途径给药的药物组合物。

14. 发明申请

US20120208189A1 METHODS FOR ISOLATION, IDENTIFICATION, AND QUANTIFICATION OF MIRNAS 审中-公开
标题翻译： MIRNAS的隔离，识别和定量方法
公开(公告)号：US20120208189A1
公开(公告)日：2012-08-16
申请号：US13350277
申请日：2012-01-13
申请人： Tom Xu , Christopher Trinh , Carole Bornarth , Brian Evans , Mousumi Rath , Kathy Tran
发明人： Tom Xu , Christopher Trinh , Carole Bornarth , Brian Evans , Mousumi Rath , Kathy Tran
IPC分类号： C12Q1/68 , C07H1/08 , C07H21/02
CPC分类号： C07H21/02 , C12N15/1006 , C12Q1/6809 , C12Q1/6834 , C12Q1/6876 , C12Q2600/178 , C12Q2525/207 , C12Q2563/149
摘要： Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.
摘要翻译：公开了用于分离，鉴定和定量miRNA和其它小RNA（包括但不限于siRNA，mRNA和snRNA）的方法和组合物和试剂盒。还公开了诊断疾病或其进展的方法。

15. 发明申请

US20090312325A1 Quinoline Derivatives As Phosphodiesterase Inhibitors 审中-公开
标题翻译：喹啉衍生物作为磷酸二酯酶抑制剂
公开(公告)号：US20090312325A1
公开(公告)日：2009-12-17
申请号：US12474324
申请日：2009-05-29
申请人： Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
发明人： Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
IPC分类号： A61K31/4709 , C07D401/12 , C07D417/12 , C07D403/12 , C07D215/38 , A61K31/47 , A61K31/5377 , A61P29/00 , A61P37/08
CPC分类号： C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要： There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译：根据本发明提供新的式（I）化合物或其药学上可接受的盐，其中R1，R2，R19，R20和R34如说明书中所述，其制备方法，含有它们的制剂及其在治疗炎症性疾病。

16. 发明授权

US07572915B2 Quinoline derivatives as phosphodiesterase inhibitors 失效
公开(公告)号：US07572915B2
公开(公告)日：2009-08-11
申请号：US11349677
申请日：2006-02-08
申请人： Michael David Barker , Anthony William Dean , Brian Evans , Stuart Holman , Michael Woodrow
发明人： Michael David Barker , Anthony William Dean , Brian Evans , Stuart Holman , Michael Woodrow
IPC分类号： C07D215/38
CPC分类号： C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要： There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.

17. 发明申请

US20070185878A1 TRANSCRYPTION OF DIGITAL CONTENT BETWEEN CONTENT PROTECTION SYSTEMS 有权
标题翻译：内容保护系统之间的数字内容的传输
公开(公告)号：US20070185878A1
公开(公告)日：2007-08-09
申请号：US11276496
申请日：2006-03-02
申请人： Scott Fierstein , Brian Evans , Geoffrey Dunbar , James Alkove , Daniel Rosenstein , Matthew Howard , Ming Ma , Alexandre Grigorovitch
发明人： Scott Fierstein , Brian Evans , Geoffrey Dunbar , James Alkove , Daniel Rosenstein , Matthew Howard , Ming Ma , Alexandre Grigorovitch
IPC分类号： G06F17/30
CPC分类号： G06F21/10 , G06F2221/0728
摘要： Technology for protecting a digital content including a first content protection system capable of decrypting the digital content, the digital content including an inclusion list; a linkable library providing access for an application to the functionality of the first content protection system, the application including a second content protection system; and a means for evaluating the second content protection system to determine if the second content protection system is on the inclusion list.
摘要翻译：用于保护数字内容的技术，包括能够解密数字内容的第一内容保护系统，数字内容包括列表; 提供对第一内容保护系统的功能的应用访问的可链接库，所述应用包括第二内容保护系统; 以及用于评估第二内容保护系统以确定第二内容保护系统是否在包含列表上的装置。

18. 发明申请

US20060242078A1 Rights management system for streamed multimedia content 有权
标题翻译：流媒体内容的权限管理系统
公开(公告)号：US20060242078A1
公开(公告)日：2006-10-26
申请号：US11113160
申请日：2005-04-22
申请人： Brian Evans , Clifford Strom , Daniel Rosenstein
发明人： Brian Evans , Clifford Strom , Daniel Rosenstein
IPC分类号： G06F17/60
CPC分类号： G06Q10/06
摘要： A computing device segregates licenses for corresponding content according to relatively short lived licenses for relatively short lived content and relatively long lived licenses for relatively long lived content. The computing device stores the relatively short lived licenses in a more temporary and volatile license store, and the relatively long lived licenses in a more permanent and non-volatile license store. Thus, the relatively short lived licenses are deleted when the temporary license store is turned off and do not create disorder in the permanent license store.
摘要翻译：计算设备根据相对较短寿命的内容相对较短的许可证和相对较长寿命内容的相对长寿命的许可证，对相应的内容进行许可。计算设备将相对较短的许可证存储在更临时和易失性的许可证存储中，以及在更永久和非易失性许可证存储中的相对长寿命的许可证。因此，当临时许可证存储关闭并且不会在永久许可证存储中产生混乱时，相对较短的寿命许可证被删除。

19. 发明申请

US20060085646A1 Device certificate self-individualization 有权
标题翻译：设备证书自身个性化
公开(公告)号：US20060085646A1
公开(公告)日：2006-04-20
申请号：US10968462
申请日：2004-10-18
申请人： Benjamin Cutter , Clifford Strom , Brian Evans , Amit Jain , Michael Siu
发明人： Benjamin Cutter , Clifford Strom , Brian Evans , Amit Jain , Michael Siu
IPC分类号： H04L9/00
CPC分类号： G06F21/10 , H04L9/3265 , H04L2209/603
摘要： Generating a device certificate. A method of generating a device certificate comprising forming a template that will generate a device certificate upon the occurrence of a triggering event, filling in an authorization root certificate section of the template; filling in an authorization certificate section of the template, filling in a group certificate section of the template, and forming a device certificate section of the template.
摘要翻译：生成设备证书。一种生成设备证书的方法，包括形成在发生触发事件时将生成设备证书的模板，填写模板的授权根证书部分; 填写模板的授权证书部分，填写模板的组合证书部分，并形成模板的设备证书部分。

20. 发明授权

US5703240A Piperidine derivatives 失效
标题翻译：哌啶衍生物
公开(公告)号：US5703240A
公开(公告)日：1997-12-30
申请号：US612843
申请日：1996-03-21
申请人： Duncan Robert Armour , Brian Evans , David Middlemiss , Alan Naylor , Neil Anthony Pegg , Maria Victoria Vinader , Gerard Martin Paul Giblin , Tania Hubbard , Michael Menteith Hann , Xiao-Qing Lewell , Stephen Paul Watson
发明人： Duncan Robert Armour , Brian Evans , David Middlemiss , Alan Naylor , Neil Anthony Pegg , Maria Victoria Vinader , Gerard Martin Paul Giblin , Tania Hubbard , Michael Menteith Hann , Xiao-Qing Lewell , Stephen Paul Watson
IPC分类号： A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4523 , A61K31/454 , A61P1/00 , A61P1/08 , A61P25/04 , A61P29/00 , A61P43/00 , C07D20060101 , C07D211/56 , C07D401/10 , C07D401/12
CPC分类号： C07D401/12
摘要： The present invention relates to piperidine derivatives of formula (I) ##STR1## wherein R.sup.1 is a C.sub.1-4 alkoxy group; R.sup.2 is ##STR2## R.sup.3 is a hydrogen or halogen atom; R.sup.4 and R.sup.5 may each independently represent a hydrogen or halogen atom, or a C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl group; R.sup.6 is a hydrogen atom, a C.sub.1-4 alkyl, (CH.sub.2).sub.m cyclopropyl, --S(O).sub.n C.sub.1-4 alkyl, phenyl, NR.sup.7 R.sup.8, CH.sub.2 C(O)CF.sub.3 or trifluoromethyl group; R.sup.7 and R.sup.8 may each independently represent a hydrogen atom, or a C.sub.1-4 alkyl or acyl group; x represents zero or 1; n represents zero, 1 or 2; m represents zero or 1; and pharmaceutically acceptable salts and solvates thereof; to processes for their preparation; and their use in the treatment of conditions mediated by tachykinins.
摘要翻译： PCT No.PCT / EP94 / 03129 Sec。 371日期1996年3月21日 102（e）1996年3月21日PCT PCT 1994年9月20日PCT公布。第WO95 / 08549号公报日期：1995年3月30日本发明涉及式（I）的哌啶衍生物其中R 1为C 1-4烷氧基; R 2是氢或卤素原子; R 4和R 5可各自独立地表示氢或卤素原子，或C 1-4烷基，C 1-4烷氧基或三氟甲基; R6是氢原子，C1-4烷基，（CH2）环丙基，-S（O）nC1-4烷基，苯基，NR7R8，CH2C（O）CF3或三氟甲基; R 7和R 8可各自独立地表示氢原子或C 1-4烷基或酰基; x表示零或1; n表示0，1或2; m表示0或1; 及其药学上可接受的盐和溶剂合物; 进行准备; 及其用于治疗由速激肽介导的病症。

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