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11. 发明授权

US07804986B2 System and method for detecting intervertebral disc alignment using vertebrae segmentation 有权
标题翻译：使用椎骨分割检测椎间盘对齐的系统和方法
公开(公告)号：US07804986B2
公开(公告)日：2010-09-28
申请号：US11468852
申请日：2006-08-31
申请人： Shang-Hong Lai , Benjamin Odry , Li Zhang
发明人： Shang-Hong Lai , Benjamin Odry , Li Zhang
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/103 , A61B5/4504 , G06T7/0012 , G06T7/136 , G06T7/187 , G06T2207/10088 , G06T2207/20016 , G06T2207/20036 , G06T2207/20101 , G06T2207/30012
摘要： A computer-implemented method for intervertebral disc alignment includes providing a spine image and a click point on the spine image, applying an adaptive thresholding technique to segment vertebrae regions at the click point from the spine image, and filtering segmented vertebrae regions with a morphological operation. The method further includes estimating a multi-scale orientation field from filtered segmented vertebrae regions, extracting an intervertebral disc region by applying region growing for each scale, integrating the multi-scale orientation field in a locally segmented intervertebral disc region based on the intervertebral disc region, estimating a disc centerline from the filtered segmented vertebrae regions, and fusing an integrated multi-scale orientation field with the disc centerline based on associated confidence measures to provide an intervertebral disc alignment.
摘要翻译：用于椎间盘对准的计算机实现的方法包括在脊柱图像上提供脊柱图像和点击点，应用自适应阈值技术来从脊柱图像在点击点处分割椎骨区域，以及用形态学操作来过滤分割的椎骨区域。该方法还包括从过滤的分段椎骨区域估计多尺度取向场，通过应用针对每个鳞片的生长区域来提取椎间盘区域，基于椎间盘区域将局部分割的椎间盘区域中的多尺度取向场积分从滤波的分段椎骨区域估计椎间盘中心线，并且基于相关联的置信度量度将整合的多尺度取向场与椎间盘中心线融合以提供椎间盘对准。

12. 发明申请

US20070127802A1 Method and System for Automatic Lung Segmentation 有权
标题翻译：自动肺分割方法与系统
公开(公告)号：US20070127802A1
公开(公告)日：2007-06-07
申请号：US11565711
申请日：2006-12-01
申请人： Benjamin Odry , Shuping Qing , Hong Shen
发明人： Benjamin Odry , Shuping Qing , Hong Shen
IPC分类号： G06K9/00
CPC分类号： G06K9/4638 , G06K2209/05 , G06T7/11 , G06T7/12 , G06T2207/10081 , G06T2207/30061
摘要： Disclosed is a systematic way of automatically segmenting lung regions. To increase the efficiency of a lung segmentation technique, a region-based technique, such as region growing, is performed by a computer on a middle slice of the CT volume. A contour-based technique is then used for a plurality of non-middle slices of the CT volume. This allows the implementation to be multithreaded and results in an improvement in the segmentation algorithm's efficiency.
摘要翻译：公开了一种自动分割肺部区域的系统方法。为了提高肺分割技术的效率，基于区域生长的区域技术由计算机在CT体积的中间切片上进行。然后将基于轮廓的技术用于CT体积的多个非中间切片。这允许实现是多线程的，并且导致分段算法的效率的改进。

13. 发明申请

US20070071301A1 SYSTEM AND METHOD FOR VISUALIZING AIRWAYS FOR ASSESSMENT 有权
标题翻译：用于可视化航空的评估系统和方法
公开(公告)号：US20070071301A1
公开(公告)日：2007-03-29
申请号：US11470287
申请日：2006-09-06
申请人： Atilla Kiraly , Benjamin Odry , Carol Novak
发明人： Atilla Kiraly , Benjamin Odry , Carol Novak
IPC分类号： G06K9/00 , A61B5/05 , A61B5/08
CPC分类号： G06T7/11 , G06T2207/10081 , G06T2207/20164 , G06T2207/30061
摘要： A method for visualizing airways in chest images, includes: computing a distance map of a segmented bronchial tree; extracting data from the segmented bronchial tree using the distance map; and visualizing a three-dimensional (3D) image of the segmented bronchial tree color-coded according to the extracted data.
摘要翻译：一种可视化胸部图像气道的方法，包括：计算分段支气管树的距离图; 使用距离图从分段支气管树提取数据; 以及根据提取的数据可视化经分段的支气管树的三维（3D）图像。

14. 发明申请

US20070049839A1 SYSTEM AND METHOD FOR AUTOMATED AIRWAY EVALUATION FOR MULTI-SLICE COMPUTED TOMOGRAPHY (MSCT) IMAGE DATA USING AIRWAY LUMEN DIAMETER, AIRWAY WALL THICKNESS AND BRONCHO-ARTERIAL RATIO 审中-公开
标题翻译：自动航空评估系统和方法，用于使用航空公司的直径，航空公司的墙壁厚度和BRONCHO-ARTERIAL比例的多层次计算机图像（MSCT）图像数据
公开(公告)号：US20070049839A1
公开(公告)日：2007-03-01
申请号：US11465548
申请日：2006-08-18
申请人： Benjamin Odry , Atilla Kiraly , Carol Novak
发明人： Benjamin Odry , Atilla Kiraly , Carol Novak
IPC分类号： A61B5/08
CPC分类号： A61B5/08 , A61B6/032 , G06F19/321
摘要： A method for evaluating an airway in a bronchial tree, includes: segmenting a bronchial tree; modeling the segmented bronchial tree; computing a first ratio for an airway in the segmented and modeled bronchial tree, wherein the first ratio is a ratio between a diameter of the airway lumen and a diameter of an artery accompanying the airway; computing a second ratio for the airway, wherein the second ratio is a ratio between the diameter of the artery and a thickness of the airway wall; or computing a tapering index for the airway, wherein the tapering index indicates a tapering of the diameter of the airway lumen; scoring and color coding the first ratio, second ratio or tapering index; and visualizing the segmented and modeled bronchial tree color coded according to the first ratio, second ratio or tapering index.
摘要翻译：一种用于评估支气管树中气道的方法，包括：分割支气管树; 建模分段支气管树; 计算分段和建模的支气管树中的气道的第一比率，其中所述第一比率是所述气道腔的直径和伴随所述气道的动脉的直径之间的比率; 计算所述气道的第二比率，其中所述第二比率是所述动脉的直径与所述气道壁的厚度之间的比率; 或计算气道的锥形折射率，其中锥形指数表示气道腔的直径的渐缩; 第一比例，第二比例或渐变指数的得分和颜色编码; 并根据第一比率，第二比例或渐缩指数可视化分段和建模的支气管树颜色编码。

15. 发明申请

US20050002548A1 Automatic detection of growing nodules 审中-公开
标题翻译：自动检测生长结节
公开(公告)号：US20050002548A1
公开(公告)日：2005-01-06
申请号：US10869291
申请日：2004-06-16
申请人： Carol Novak , Hong Shen , Benjamin Odry
发明人： Carol Novak , Hong Shen , Benjamin Odry
IPC分类号： G06K9/00 , G06K9/68 , G06T7/00
CPC分类号： G06T7/0012 , G06T2207/30061
摘要： A system and method for detecting a growing nodule in multi-slice data detects a nodule candidate in a later scan, and matches a location of the nodule candidate in the later scan to a location in an earlier scan, wherein the earlier and later scans are of the same patient. The system and method segments the nodule candidate in the earlier and later scans, compares volumes from each segmentation, and determines a nodule, wherein the nodule is determined to be larger or newly appeared in the later scan as compared to the earlier scan.
摘要翻译：用于检测多切片数据中的生长结节的系统和方法在稍后的扫描中检测结节候选，并将稍后扫描中的结节候选的位置与早期扫描中的位置相匹配，其中较早和较晚的扫描是的同一病人。系统和方法在较早和较晚的扫描中分割结节候选者，比较每个分割的体积，并确定结节，其中确定结节比较早的扫描更晚或新出现在稍后的扫描中。

16. 发明申请

US20150018664A1 Assessment of Traumatic Brain Injury 有权
标题翻译：创伤性脑损伤评估
公开(公告)号：US20150018664A1
公开(公告)日：2015-01-15
申请号：US14330814
申请日：2014-07-14
申请人： Francisco Pereira , Benjamin Odry , Hasan Ertan Cetingul
发明人： Francisco Pereira , Benjamin Odry , Hasan Ertan Cetingul
IPC分类号： A61B5/055 , A61B5/00
CPC分类号： A61B5/055 , A61B5/0042 , A61B5/4064 , A61B5/7267 , G06F19/00 , G06T7/11 , G06T2207/10088 , G06T2207/20128 , G06T2207/30016 , G16H50/20
摘要： Traumatic brain injury (TBI) in a patient is assessed. A TBI diagnosis for the patient is determined based on features from MRI data, such as anatomical features, functional features, diffusion features, connectivity features from functional MRI, connectivity features from diffusion MRI, and/or network features from the connectivity features. The TBI diagnosis is determined using a trained classifier. The classifier synthesizes the features into a single number (e.g., a confidence in the prediction of the diagnosis) and indicates the features most responsible for the diagnosis. The disease trajectory for a given patient may be predicted using the trained classifier.
摘要翻译：评估患者的创伤性脑损伤（TBI）。根据MRI数据的特征（如解剖特征，功能特征，扩散特征，功能MRI的连接特征，扩散MRI的连接特征和/或来自连接特征的网络特征）确定患者的TBI诊断。使用训练有素的分类器确定TBI诊断。分类器将特征合成为单个数字（例如，对诊断的预测的置信度），并且指示对诊断最负责的特征。可以使用经过训练的分类器来预测给定患者的疾病轨迹。

17. 发明授权

US07756316B2 Method and system for automatic lung segmentation 有权
标题翻译：自动肺分割的方法和系统
公开(公告)号：US07756316B2
公开(公告)日：2010-07-13
申请号：US11565711
申请日：2006-12-01
申请人： Benjamin Odry , Shuping Qing , Hong Shen
发明人： Benjamin Odry , Shuping Qing , Hong Shen
IPC分类号： G06K9/00
CPC分类号： G06K9/4638 , G06K2209/05 , G06T7/11 , G06T7/12 , G06T2207/10081 , G06T2207/30061
摘要： Disclosed is a systematic way of automatically segmenting lung regions. To increase the efficiency of a lung segmentation technique, a region-based technique, such as region growing, is performed by a computer on a middle slice of the CT volume. A contour-based technique is then used for a plurality of non-middle slices of the CT volume. This allows the implementation to be multithreaded and results in an improvement in the segmentation algorithm's efficiency.
摘要翻译：公开了一种自动分割肺部区域的系统方法。为了提高肺分割技术的效率，基于区域生长的区域技术由计算机在CT体积的中间切片上进行。然后将基于轮廓的技术用于CT体积的多个非中间切片。这允许实现是多线程的，并且导致分段算法的效率的改进。

18. 发明申请

US20070127800A1 Branch Extension Method For Airway Segmentation 有权
标题翻译：分支延伸方法用于气道分割
公开(公告)号：US20070127800A1
公开(公告)日：2007-06-07
申请号：US11565720
申请日：2006-12-01
申请人： Bjoern Coenen , Atilla Kiraly , Carol Novak , Benjamin Odry
发明人： Bjoern Coenen , Atilla Kiraly , Carol Novak , Benjamin Odry
IPC分类号： G06K9/00
CPC分类号： G06T7/11 , G06T2207/10072 , G06T2207/20101 , G06T2207/30061
摘要： A branch extension method and system for segmenting airways in 3D image data is disclosed. An initial airway segmentation is obtained from the 3D image data. Terminal branches of segmented airways of the initial airway segmentation are identified. The segmentation of the terminal branches is then extended. The segmentation of the terminal branches can be extended using various segmentation techniques. This method can use complex segmentation techniques to extend the terminal branches without having a large impact to the overall speed of the segmentation.
摘要翻译：公开了一种用于分割3D图像数据中的气道的分支扩展方法和系统。从3D图像数据获得初始气道分割。确定初始气道分割的分段气道末端分支。然后扩展终端分支的分段。可以使用各种分割技术来扩展终端分支的分割。该方法可以使用复杂的分割技术来扩展终端分支，而不会对分割的整体速度产生很大的影响。

19. 发明申请

US20070064988A1 SYSTEM AND METHOD FOR GROUPING AIRWAYS AND ARTERIES FOR QUANTITATIVE ANALYSIS 失效
标题翻译：用于定量分析的航空和航空分类系统和方法
公开(公告)号：US20070064988A1
公开(公告)日：2007-03-22
申请号：US11470294
申请日：2006-09-06
申请人： Benjamin Odry , Atilla Kiraly , Carol Novak
发明人： Benjamin Odry , Atilla Kiraly , Carol Novak
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2207/30101
摘要： A method for grouping airway and artery pairs, includes: computing a two-dimensional (2D) cross-section of an airway; identifying regions of high-intensity in the 2D cross-section; computing a first indicator for each of the high intensity regions, wherein the first indicator is an orientation measure of the high intensity region with respect to the airway; computing a second indicator for each of the high intensity regions, wherein the second indicator is a circularity measure of the high intensity region; computing a third indicator for each of the high intensity regions, wherein the third indicator is a proximity measure of the high intensity region with respect to the airway; summing the first through third indicators for each of the high intensity regions to obtain a score for each of the high intensity regions; and determining which of the high intensity regions is an artery corresponding to the airway based on its score.
摘要翻译：一种用于分组气道和动脉对的方法，包括：计算气道的二维（2D）横截面; 识别2D横截面中高强度的区域; 计算每个所述高强度区域的第一指示符，其中所述第一指示符是所述高强度区域相对于所述气道的取向测量; 计算每个高强度区域的第二指示符，其中第二指示符是高强度区域的圆度度量; 计算每个高强度区域的第三指示符，其中第三指示符是相对于气道的高强度区域的接近度量; 对每个高强度区域的第一至第三指标求和，以获得每个高强度区域的得分; 并且基于其得分确定哪个高强度区域是对应于气道的动脉。

20. 发明申请

US20070049840A1 SYSTEM AND METHOD FOR DETERMINING A SIZE OF AN AIRWAY LUMEN AND A THICKNESS OF AN AIRWAY WALL 有权
标题翻译：用于确定航空公司的大小和航空的厚度的系统和方法
公开(公告)号：US20070049840A1
公开(公告)日：2007-03-01
申请号：US11465516
申请日：2006-08-18
申请人： Benjamin Odry , Atilla Kiraly , Carol Novak
发明人： Benjamin Odry , Atilla Kiraly , Carol Novak
IPC分类号： A61B5/08
CPC分类号： A61B5/08 , A61B6/032 , G06F19/00 , G06F19/321 , G06T7/12 , G06T7/13 , G06T7/155 , G06T7/62 , G06T2207/20044 , G06T2207/30061 , G06T2207/30172
摘要： A method for determining a size of an airway lumen and a thickness of an airway wall includes: computing a centerline of an airway; computing a three-dimensional (3D) gradient of a volume of the airway within a first threshold; positioning a tube along the centerline; iteratively expanding the tube by increasing its radius until the radius of the tube reaches the first threshold; determining inner and outer radii of the tube by checking the 3D gradient computed along an x-axis and a y-axis of the tube at a boundary of the tube at each iteration; and fitting the tube to the airway by using the determined inner and outer radii, wherein the inner radius of the fit tube is half a diameter of the airway lumen and the outer radius of the fit tube minus the inner radius of the fit tube is a thickness of the airway wall.
摘要翻译：用于确定气道腔的尺寸和气道壁的厚度的方法包括：计算气道的中心线; 计算在第一阈值内的气道体积的三维（3D）梯度; 沿着中心线定位管; 通过增加其半径直到管的半径达到第一阈值来迭代地膨胀管; 通过检查在每次迭代的管的边界处沿着管的x轴和y轴计算的3D梯度来确定管的内部和外部半径; 并且通过使用所确定的内半径和外半径将管装配到气道，其中配合管的内半径为气道腔的直径的一半，并且配合管的外半径减去配合管的内半径为气道壁厚度。

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