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    • 11. 发明申请
    • ADHESIVE PATCH
    • 胶粘贴
    • US20140234393A1
    • 2014-08-21
    • US14241622
    • 2012-08-31
    • Toshikazu Komoda
    • Toshikazu Komoda
    • A61K9/70A61K31/27
    • A61K9/7061A61K31/27
    • Provided is an adhesive patch which has excellent rivastigmine storage stability and an increased skin permeability of rivastigmine to such an extent that the amount of percutaneous absorption required for treating Alzheimer's disease is obtained.This adhesive patch includes a backing and an adhesive layer containing rivastigmine and an alkyl(meth)acrylate-based copolymer that does not contain any acrylic monomer component having a carboxy group, the adhesive layer being laid on one side of and integrated with the backing.
    • 本发明提供一种胶粘贴剂,其具有极佳的利伐斯的明储存稳定性和增加的拉伐斯的明皮肤渗透性,使得获得治疗阿尔茨海默氏病所需的经皮吸收量。 该粘合贴剂包括背衬和粘合剂层,该粘合剂层含有不含任何具有羧基的丙烯酸类单体组分的(或)(甲基)丙烯酸烷基酯共聚物,所述粘合剂层铺设在背衬的一侧并与其一体化。