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11. 发明授权

US07766846B2 Rapid blood expression and sampling 有权
标题翻译：快速血液表达和抽样
公开(公告)号：US07766846B2
公开(公告)日：2010-08-03
申请号：US12020766
申请日：2008-01-28
申请人： Daniel Wong , Paul Patel
发明人： Daniel Wong , Paul Patel
IPC分类号： A61B5/00 , A61B17/14 , A61B17/32 , B65D81/00
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150152 , A61B5/150358 , A61B5/150419 , A61B5/150427 , A61B5/150503 , A61B5/150816 , A61B5/150824 , A61B5/150954 , A61B5/15109 , A61B5/15113 , A61B5/15123
摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, the device further comprising a fluid receiving means remotely spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.
摘要翻译：体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，所述装置还包括与收集区远离间隔开的流体接收装置，使得收集区中的体液不会最初接触流体接收装置。收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。流体接收装置可以具有用于进行分析反应的测试区域。来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。

12. 发明申请

US20090118752A1 DEVICES AND METHODS FOR EXPRESSION OF BODILY FLUIDS FROM AN INCISION 有权
标题翻译：用于从侵入体表达体液的装置和方法
公开(公告)号：US20090118752A1
公开(公告)日：2009-05-07
申请号：US12353666
申请日：2009-01-14
申请人： Edward Perez , Charles C. Raney , Paul Patel
发明人： Edward Perez , Charles C. Raney , Paul Patel
IPC分类号： A61B17/32 , A61B19/00 , A61B5/00
CPC分类号： A61B5/14514 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/15194
摘要： Systems and methods for the expression of bodily fluid from an incision in the skin include devices which bear against the skin in a manner to retain the fluid adjacent the incision site and urge the fluid inwardly toward the incision. Systems utilize a constricting member, a bi-stable expression member, or a pressing member. The present invention further encompasses combinations of the foregoing expression systems with each other, as well as with other expression devices known in the art. Moreover, the invention includes the combination of the expression systems with incising, sampling and/or testing systems, particularly in a single, integrated device. The present invention also contemplates the associated methods for expressing bodily fluid from an incision, including in combination with methods for incising, sampling and/or testing of the bodily fluid.
摘要翻译：用于从皮肤切口表达体液的系统和方法包括以保持与切口部位相邻的流体并将流体向内朝向切口推动的方式抵靠皮肤的装置。系统利用收缩构件，双稳态表达构件或按压构件。本发明还包括上述表达系统彼此的组合，以及本领域已知的其它表达装置。此外，本发明包括表达系统与切割，采样和/或测试系统的组合，特别是在单个集成设备中。本发明还考虑了用于从切口表达体液的相关方法，包括结合用于切开，取样和/或测试体液的方法。

13. 发明授权

US07488298B2 Integrated lancing test strip with capillary transfer sheet 失效
标题翻译：带毛细管转移片的集成穿刺试纸
公开(公告)号：US07488298B2
公开(公告)日：2009-02-10
申请号：US10961640
申请日：2004-10-08
申请人： Paul Patel , Edward P. Perez
发明人： Paul Patel , Edward P. Perez
IPC分类号： A61B5/00 , B65D81/00
CPC分类号： A61B5/14532
摘要： An integrated bodily fluid sampling device includes a lancet, a test strip attached to the lancet, and a flexible sheet extending from the test strip. The lancet and the flexible sheet form a gap sized to draw bodily fluid onto the test strip via capillary action. Further, a sampling end portion of the flexible sheet is shaped to enhance capillary action of the sheet. In one form, a removable film covers the lancet and forms a seal with the flexible sheet such that the seal surrounds a lancet tip. In another form, an insulating layer covers a portion of the lancet to prevent electrical interference between the lancet and an electrical testing system on the test strip and ensure an accurate analysis of the bodily fluid.
摘要翻译：整体式体液取样装置包括刺血针，连接到刺血针的测试条和从测试条延伸的柔性片。柳叶刀和柔性片形成一个间隙，其大小通过毛细管作用将体液吸引到测试条上。此外，柔性片的采样端部成形为增强片材的毛细作用。在一种形式中，可移除的膜覆盖刺血针并与柔性片形成密封，使得密封件围绕刺血针尖端。在另一种形式中，绝缘层覆盖刺血针的一部分，以防止刺血针与测试条上的电气测试系统之间的电干扰，并确保对体液的准确分析。

14. 发明授权

US09326718B2 Blood glucose measurement for small blood volume 有权
标题翻译：血糖测量小血量
公开(公告)号：US09326718B2
公开(公告)日：2016-05-03
申请号：US12845512
申请日：2010-07-28
申请人： Wolfgang Petrich , Christian Vrancic , Daniel Wong , Paul Patel
发明人： Wolfgang Petrich , Christian Vrancic , Daniel Wong , Paul Patel
IPC分类号： A61B5/157 , B65D81/00 , A61B5/15 , A61B5/145
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150152 , A61B5/150358 , A61B5/150419 , A61B5/150427 , A61B5/150503 , A61B5/150816 , A61B5/150824 , A61B5/150954 , A61B5/15109 , A61B5/15113 , A61B5/15123
摘要： A system is proposed for detection of at least one analyte in a body fluid, in particular for detection of blood glucose. The system is designed to generate a sample of the body fluid and to transfer at least some of the sample to at least one test element, in particular a test panel. The system is designed such that a time period between the generation of the sample and the application to the test element is less than 1 second, preferably less than 500 ms.
摘要翻译：提出了用于检测体液中至少一种分析物的系统，特别是用于检测血糖。该系统设计成产生体液样品并将至少一些样品转移到至少一个测试元件，特别是测试面板。该系统被设计成使得样品生成和应用到测试元件之间的时间段小于1秒，优选小于500ms。

15. 发明申请

US20060079810A1 Integrated lancing test strip with capillary transfer sheet 失效
公开(公告)号：US20060079810A1
公开(公告)日：2006-04-13
申请号：US10961640
申请日：2004-10-08
申请人： Paul Patel , Edward Perez
发明人： Paul Patel , Edward Perez
IPC分类号： A61B5/00
CPC分类号： A61B5/14532
摘要： An integrated bodily fluid sampling device includes a lancet, a test strip attached to the lancet, and a flexible sheet extending from the test strip. The lancet and the flexible sheet form a gap sized to draw bodily fluid onto the test strip via capillary action. Further, a sampling end portion of the flexible sheet is shaped to enhance capillary action of the sheet. In one form, a removable film covers the lancet and forms a seal with the flexible sheet such that the seal surrounds a lancet tip. In another form, an insulating layer covers a portion of the lancet to prevent electrical interference between the lancet and an electrical testing system on the test strip and ensure an accurate analysis of the bodily fluid.

16. 发明申请

US20060030788A1 Apparatus and method for extracting bodily fluid utilizing a flat lancet 审中-公开
标题翻译：使用扁平刺血针提取体液的装置和方法
公开(公告)号：US20060030788A1
公开(公告)日：2006-02-09
申请号：US10911252
申请日：2004-08-04
申请人： Daniel Wong , Charles Raney , Paul Patel , Steven Roe
发明人： Daniel Wong , Charles Raney , Paul Patel , Steven Roe
IPC分类号： A61B5/00
CPC分类号： A61B5/14514 , A61B5/150022 , A61B5/150106 , A61B5/150175 , A61B5/150213 , A61B5/150282 , A61B5/150358 , A61B5/150458 , A61B5/150465 , A61B5/150503 , A61B5/15113 , A61B5/1519 , A61B5/157
摘要： A bodily fluid sampling device is operable to rupture the skin surface at normal and oblique angles utilizing a flat lancet of specified thickness and at least one cutting surface inclined less than eighty degrees (80°) from the longitudinal axis of the flat lancet. The flat lancet thickness and cutting surface geometry minimize pain while maximizing the amount of emerged bodily fluid. The device limits the depth to which the flat lancet penetrates the skin to further minimize pain and may urge the bodily fluid from the rupture site. The bodily fluid emerging from the rupture site is transported to a test device that tests the bodily fluid for particular properties and characteristics.
摘要翻译：身体液体采样装置可操作以使用特定厚度的扁平的柳叶刀和从平胸针的纵轴倾斜小于八十度（80°）的至少一个切割表面以正常和倾斜的角度破裂皮肤表面。扁平的柳叶刀厚度和切割表面几何形状使疼痛减到最小，同时使出现的体液量达到最大。该装置限制了平刺血针穿透皮肤的深度，以进一步减少疼痛，并可以从破裂部位推动体液。从破裂部位出现的体液被运送到测试体液，以测试体液的特性和特性。

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