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11. 发明申请

US20080045594A1 Use of at Least One Conjugated Triene-Containing Fatty Acid for Preparing a Medicine for Treating Inflammation 审中-公开
标题翻译：使用至少一种含共轭三烯的脂肪酸来制备治疗炎症的药物
公开(公告)号：US20080045594A1
公开(公告)日：2008-02-21
申请号：US11572769
申请日：2005-07-20
申请人： Antoine Piccirilli , Nathalie Piccardi , Philippe Miska
发明人： Antoine Piccirilli , Nathalie Piccardi , Philippe Miska
IPC分类号： A61K31/20 , A61P29/00 , C07C51/41
CPC分类号： A61K31/202 , A61K36/185 , A61K36/28 , A61K36/42 , A61K36/428 , A61K36/73 , A61K36/84
摘要： The invention concerns the use of at least one conjugated triene-containing fatty acid for preparing a medicine for treating inflammation selected among the group consisting of alpha-eleostearic acid, catalpic acid, calendic acid, jacaric acid, licanic acid and beta-eleostearic acid for making a medicine for treating inflamatory diseases and/or metabolic disorders following an inflammation. The inflammatory diseases and/or metabolic disorders following an inflammation may be skin cancers, sun burn, benign summer light eruption, allergic and/or irritative reactions, gingivitis and periodontitis, vulvitis and vaginitis or arthritis and arthrosis. The medicine also enables healing to be promoted. Said fatty acid conjugates can also be used in the cosmetic treatment of cellulitis.
摘要翻译：本发明涉及使用至少一种含共轭三烯的脂肪酸来制备用于治疗炎症的药物，所述药物选自由α-蓖麻酸，catal酸，胼ic酸，茉莉酸，ican酸和β-蒿酸组成的组，其用于制造治疗炎性疾病和/或炎症后的代谢紊乱的药物。炎性疾病和/或炎症后的代谢紊乱可能是皮肤癌，太阳烧伤，良性夏季光线爆发，过敏性和/或刺激性反应，牙龈炎和牙周炎，外阴炎和阴道炎或关节炎和关节炎。该药也能使愈合得到提升。所述脂肪酸缀合物也可用于蜂窝织炎的美容治疗。

12. 发明申请

US20070098823A1 Maca extract and cosmetic composition containing such an extract 有权
标题翻译：含有这种提取物的麦汁提取物和化妆品组合物
公开(公告)号：US20070098823A1
公开(公告)日：2007-05-03
申请号：US10561271
申请日：2004-06-17
申请人： Nathalie Piccardi , Antoine Piccirilli , Philippe Msika , Francois Paul
发明人： Nathalie Piccardi , Antoine Piccirilli , Philippe Msika , Francois Paul
IPC分类号： A61K36/31
CPC分类号： A61K8/645 , A61K8/97 , A61Q19/08
摘要： The invention relates to a method for extracting substances from maca, to the obtained extract, to a cosmetic and pharmaceutical composition containing said extract, and to the use thereof as an anti-aging cosmetic agent. The method is characterized by a step involving the use of an enzymatic hydrolysis of proteins.
摘要翻译：本发明涉及从马卡提取物质，所得提取物，含有所述提取物的化妆品和药物组合物的方法及其作为抗衰老化妆剂的用途。该方法的特征在于涉及使用蛋白质的酶水解的步骤。

13. 发明申请

US20060194881A1 Composition comprising at least one alkanolamide to inhibit megration of langerhans cells and uses therof 有权
标题翻译：组合物，其包含至少一种烷醇酰胺以抑制朗格汉斯细胞的整理并使用该方法
公开(公告)号：US20060194881A1
公开(公告)日：2006-08-31
申请号：US11411870
申请日：2006-04-27
申请人： Philippe Msika , Nathalie Piccardi , Anthoine Piccirilli
发明人： Philippe Msika , Nathalie Piccardi , Anthoine Piccirilli
IPC分类号： A61K31/16
CPC分类号： A61K8/68 , A61K2800/75 , A61K2800/782 , A61Q19/00 , A61Q19/005
摘要： The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.
摘要翻译：本发明涉及至少含有烷醇酰胺的组合物，任选与至少一种化合物如金属蛋白酶抑制剂，PKC抑制剂，抗炎剂，舒缓剂，免疫抑制剂，离子螯合剂，恶唑啉，恶唑烷酮和氨基甲酸衍生物。本发明还涉及使用这样的组合物作为药物，特别是其用于预防或治疗过敏性和/或炎性和/或刺激性起源或由危险信号引起的皮肤病理学的用途。本发明还涉及一种用于美容治疗敏感的，刺激的，不耐受的，过敏倾向的，老化的皮肤和/或表现皮肤屏障障碍的皮肤或/或表现出非病理性免疫不平衡的方法，其包括将这样的组合物应用于皮肤和 /或粘膜。

14. 发明申请

US20060122246A1 Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite 有权
公开(公告)号：US20060122246A1
公开(公告)日：2006-06-08
申请号：US10561173
申请日：2004-06-17
申请人： Philippe Msika , Antoine Piccirlli , Nathalie Piccardi
发明人： Philippe Msika , Antoine Piccirlli , Nathalie Piccardi
IPC分类号： A61K31/421
CPC分类号： A61K8/49 , A61Q19/06
摘要： The invention relates to the cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product, and to an associated cosmetic treatment method. The invention also relates to the cosmetic use of a composition containing at least one oxazoline, serving as an active substance, for preventing and/or treating cellulite.

15. 发明授权

US08747815B2 Use of a cosmetic of pharmaceutical composition, comprising a lupeol-rich extract as an active ingredient for stimulating the synthesis of heat shock proteins 有权
标题翻译：使用药物组合物的化妆品，其包含富含富勒酚的提取物作为刺激热休克蛋白合成的活性成分
公开(公告)号：US08747815B2
公开(公告)日：2014-06-10
申请号：US10564785
申请日：2004-07-19
申请人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
发明人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
IPC分类号： A61K8/97 , A61K36/48 , A61K31/045 , A61Q19/00 , A61Q11/00
CPC分类号： A61K8/97 , A61K31/045 , A61K36/48 , A61Q11/00 , A61Q19/00 , A61Q19/08
摘要： The present invention relates to the use of a lupeol-rich extract for the production of a cosmetic or pharmaceutical composition for treating and/or preventing a connective tissue degeneration. Said invention also relates to the use of a lupeol-rich extract for the production of a pharmaceutical composition for preventing and/or treating non-inflammatory articular pathologies, periodontal diseases and stretch marks. The invention also relates to the use of a lupeol-rich extract for the production of a cosmetic composition as a cicatrizing agent, a restructuring agent and an anti-sagging agent for skin and/or mucosae.
摘要翻译：本发明涉及富含富勒索的提取物用于生产用于治疗和/或预防结缔组织变性的化妆品或药物组合物的用途。所述发明还涉及富含富勒酸的提取物用于制备用于预防和/或治疗非炎性关节病变，牙周疾病和妊娠纹的药物组合物的用途。本发明还涉及富含富勒酸的提取物用于生产化妆品组合物作为痤疮剂，重组剂和用于皮肤和/或粘膜的抗流挂剂的用途。

16. 发明授权

US08734865B2 Lupin total extract consisting of a lupin sugar extract and a lupin peptide extract, method for the production and use thereof 有权
标题翻译：由羽扇豆糖提取物和羽扇豆肽提取物组成的羽扇豆总提取物，其生产和使用方法
公开(公告)号：US08734865B2
公开(公告)日：2014-05-27
申请号：US11547031
申请日：2005-04-04
申请人： Jean-Christophe Choulot , Antoine Piccirilli , Nathalie Piccardi , Philippe Msika , François Paul
发明人： Jean-Christophe Choulot , Antoine Piccirilli , Nathalie Piccardi , Philippe Msika , François Paul
IPC分类号： A61K36/48 , A61Q5/02 , A61K31/715 , A61K8/97 , A61K36/00
CPC分类号： A61K8/645 , A61K8/64 , A61K8/73 , A61K8/97 , A61K36/48 , A61Q17/00 , A61Q19/00 , A61Q19/08
摘要： The invention relates to a composition comprising a lupin total extract consisting of a lupin sugar extract, comprising at least 50% galactooligosaccharides by weight, in relation to the weight of dry matter, and a lupin peptide extract. The composition can also contain a chromane derivative or a chromene derivative. The invention also relates to a pharmaceutical and/or cosmetic composition comprising said lupin total extract, used advantageously as an anti-inflammatory agent, which repairs the cutaneous barrier and heals, used particularly in the prevention and/or treatment of erythemas.
摘要翻译：本发明涉及包含由羽扇豆糖提取物组成的羽扇豆总提取物的组合物，所述羽扇蛋白提取物包含相对于干物质重量的至少50重量％的低聚半乳寡糖和羽扇豆肽提取物。该组合物还可以含有色度衍生物或色烯衍生物。本发明还涉及一种药物和/或化妆品组合物，其包含有利地作为抗炎剂的所述羽扇豆总提取物，其修复特别用于预防和/或治疗红斑的皮肤屏障和愈合。

17. 发明授权

US08653117B2 Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof 有权
标题翻译：包含至少一种恶唑啉以抑制朗格汉斯细胞迁移的组合物及其用途
公开(公告)号：US08653117B2
公开(公告)日：2014-02-18
申请号：US12352973
申请日：2009-01-13
申请人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
发明人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
IPC分类号： A61K31/421 , A61K38/02 , A61P35/00
CPC分类号： A61K31/42 , A61K8/49 , A61K2800/51 , A61K2800/70 , A61K2800/75 , A61K2800/782 , A61Q19/00 , A61Q19/005 , A61Q19/08 , Y10S514/861
摘要： The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
摘要翻译：本发明涉及至少含有恶唑啉的组合物，任选地与至少一种化合物如金属蛋白酶抑制剂，PKC抑制剂，抗炎剂，舒缓剂，免疫抑制剂，离子螯合剂，链烷醇酰胺，恶唑烷酮和氨基甲酸衍生物。本发明还涉及使用这种组合物作为药物，特别是用于预防或治疗过敏和/或炎性和/或刺激性起源或由危险信号引起的皮肤病理学。本发明还涉及一种用于美容治疗敏感的，刺激的，不耐受的，过敏倾向的，老化的皮肤和/或表现皮肤屏障障碍的皮肤或/或表现出非病理性免疫不平衡的皮肤和/或粘膜的方法，其包括在皮肤和/ 或粘膜。

18. 发明授权

US07629371B2 Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite 有权
标题翻译：含有至少一种作为活性物质的恶唑啉作为减肥产品和/或用于预防和/或治疗脂肪团的组合物的化妆品使用
公开(公告)号：US07629371B2
公开(公告)日：2009-12-08
申请号：US10561173
申请日：2004-06-17
申请人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
发明人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
IPC分类号： A61K31/41 , A61K31/42 , A61K31/421 , A61K8/33 , A61P17/00
CPC分类号： A61K8/49 , A61Q19/06
摘要： The invention relates to the cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product, and to an associated cosmetic treatment method. The invention also relates to the cosmetic use of a composition containing at least one oxazoline, serving as an active substance, for preventing and/or treating cellulite.
摘要翻译：本发明涉及包含至少一种作为活性物质的恶唑啉作为减肥产品的组合物的化妆品用途以及相关的美容治疗方法。本发明还涉及包含至少一种用作预防和/或治疗脂肪团的恶唑啉作为活性物质的组合物的化妆品用途。

19. 发明授权

US07511010B2 Pharmaceutical or cosmetic composition and use of a PKC inhibitor with an MMP inhibitor for inhibiting Langerhans' cell migration 有权
标题翻译：药物或化妆品组合物和PKC抑制剂与MMP抑制剂的用途，用于抑制朗格汉斯细胞迁移
公开(公告)号：US07511010B2
公开(公告)日：2009-03-31
申请号：US10416464
申请日：2001-11-14
申请人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
发明人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
IPC分类号： A61K38/00 , A61K31/13
CPC分类号： A61K31/13 , A61K8/41 , A61K8/68 , A61K31/045 , A61K31/56 , A61K36/48 , A61K2800/75 , A61Q19/00 , A61Q19/005 , A61K2300/00
摘要： The invention concerns a pharmaceutical or cosmetic composition, characterised in that it comprises at least a compound for inhibiting Langerhans' cell migration, said active compound being selected in the group consisting of protein kinase C (PKC) inhibiting compounds, matrix metalloprotease (MMP) inhibiting compounds, and combinations thereof, and at least a pharmaceutically or cosmetically acceptable carrier. Said composition enables to inhibit considerably Langerhans' cell migration induced by the presence or an allergenic agent.
摘要翻译：本发明涉及药物或化妆品组合物，其特征在于其至少包含用于抑制朗格汉斯细胞迁移的化合物，所述活性化合物选自蛋白激酶C（PKC）抑制化合物，基质金属蛋白酶（MMP）抑制剂化合物及其组合，以及至少一种药学上或化妆品上可接受的载体。所述组合物能够显着抑制由存在或变应原剂引起的朗格汉斯细胞迁移。

20. 发明申请

US20080292613A1 Food Supplement Based on Group B Vitamins, Trace Elements and -3 and/or 6- Fatty Acids and Use of This Food Supplement in the Simultaneous Treatment of Localized Cellulite and Slackening of the Skin 审中-公开
标题翻译：基于B组维生素，微量元素和-3和/或6-脂肪酸的食品补充剂和本食品补充剂同时治疗局部脂肪团和松弛皮肤的食品补充剂
公开(公告)号：US20080292613A1
公开(公告)日：2008-11-27
申请号：US12097505
申请日：2006-12-15
申请人： Philippe Msika , Nathalie Piccardi , Pascale Cochet , Michel Moreau
发明人： Philippe Msika , Nathalie Piccardi , Pascale Cochet , Michel Moreau
IPC分类号： A61K38/48 , A61K33/30 , A61K33/06 , A61K33/34 , A61K33/04 , A61P3/04 , A61K33/24 , A61K33/26 , A61K33/32
CPC分类号： A61K33/24 , A23L33/12 , A23L33/15 , A23L33/16 , A23L33/30 , A23V2002/00 , A61K31/08 , A61K31/201 , A61K31/202 , A61K33/04 , A61K33/06 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K2300/00 , A23V2200/318 , A23V2250/704 , A23V2250/1642 , A23V2250/161 , A23V2250/1882
摘要： The present invention relates to the use of a combination of group B vitamins, trace element(s), at least one oil comprising essential Ω-3 and/or Ω-6 fatty acids and an excipient suitable for oral administration, for use in the simultaneous treatment of excess weight and slackening of the skin localized in the same area. The invention also relates to a corresponding food supplement.
摘要翻译：本发明涉及B组维生素，微量元素，至少一种包含必需的ω-3和/或ω-6脂肪酸的油和适于口服给药的赋形剂的组合的用途，用于同时治疗局部在同一区域的多余重量和松弛的皮肤。本发明还涉及相应的食品补充剂。

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