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    • 12. 发明授权
    • Octalactone-containing composition, fermentation process for producing
same and organoleptic uses thereof
    • 含有八聚内酯的组合物,用于生产其的发酵方法及其感官用途
    • US5112803A
    • 1992-05-12
    • US719154
    • 1991-06-21
    • Mohamad I. FarboodLynda B. McLeanJames A. MorrisHenry A. Bondarovich
    • Mohamad I. FarboodLynda B. McLeanJames A. MorrisHenry A. Bondarovich
    • A24B15/40C11B9/00C11D3/50C12P17/04
    • C11B9/0076A24B15/406C11D3/50C12P17/04
    • Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures: ##STR2## by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure: ##STR3## wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of:Mortierella isabellina, ATCC 44583;Mortierella isabellina, ATCC 38063;Syncephalastrum racemosum, NRRL A-5889;Mortierella isabellina, IFO 7884;Mortierella ramanniana var. angulispora, IFO 8187;Mortierella isabellina, CBS 221.29; andMortierella isabellina, IFO 7873whereby gamma hydroxy octanoic acid or ester thereof defined according to the structure: ##STR4## is formed; and (ii) lactonization of the resulting gamma hydroxy octanoic acid by means of simultaneous acidification and heating according to the reaction sequence:
    • 描述了根据以下结构定义的含有八聚核苷酸的物质组合物的方法:其包括具有以下结构的立体异构体:其中包括具有以下结构的顺式步骤:(i)辛酸发酵 酸或根据通用结构定义的辛酸乙酯:其中R是氢或乙基,使用选自以下的微生物:高山被孢霉(Mortierella isabellina),ATCC 44583; 被孢霉(Mortierella isabellina),ATCC 38063; 沙门氏菌,NRRL A-5889; 高山被孢霉,IFO 7884; 高山被孢霉 angulispora,IFO 8187; 高山被孢霉,CBS 221.29; 和高山被孢霉(Mortierella isabellina),IFO 7873,由此形成根据以下结构定义的γ羟基辛酸或其酯: 和(ii)通过根据反应顺序的同时酸化和加热来对所得的γ-羟基辛酸进行内酯化: